Eating for Better Sleep & Foods that Improve Metabolic Health | Dr. Marie-Pierre St-Onge

Andrew Huberman – Huberman Lab
Andrew Huberman – Huberman LabJun 8, 2026

Why It Matters

Adequate, high‑quality sleep directly regulates hunger hormones and food choices, making it a simple lever to prevent weight gain and metabolic disease.

Key Takeaways

  • Short sleep raises ghrelin in men, lowers GLP‑1 in women.
  • Higher fiber intake boosts deep slow‑wave sleep; saturated fat reduces it.
  • Sleep‑restricted individuals consume 250‑400 extra calories nightly on average.
  • Refined carbs and sugars increase nocturnal arousals and disrupt REM.
  • Consistent 7‑8 h sleep prevents modest weight gain over weeks.

Summary

The Huberman Lab episode spotlights Dr. Marie‑Pierre St‑Onge’s pioneering work on the two‑way link between sleep duration and dietary choices. By combining population data with controlled laboratory studies, her team shows how even modest sleep curtailment reshapes appetite hormones, brain reward circuits, and subsequent food intake. Key findings reveal sex‑specific hormonal shifts: men experience a ghrelin surge, while women show reduced GLP‑1, both driving higher caloric consumption—about 250‑400 extra calories per night. Nutrient composition matters too; higher fiber correlates with deeper slow‑wave sleep, whereas saturated fats blunt deep sleep and refined carbs trigger more arousals and lighter REM. St‑Onge notes, “When sleep is restricted, reward centers light up, making high‑sugar, high‑fat foods more appealing,” and cites a two‑week trial where participants sleeping five hours gained roughly half a kilogram. The research also links chronic short sleep to gradual weight gain, echoing long‑term cohort studies of nurses who slept less than seven hours. For consumers and policymakers, the data suggest that prioritizing 7‑8 hours of quality sleep and a fiber‑rich diet can curb overeating, improve metabolic health, and blunt obesity risk, offering a low‑cost, evidence‑based strategy for public health interventions.

Original Description

Dr. Marie-Pierre St-Onge, PhD⁠, is a professor of nutritional medicine at Columbia University School of Medicine and an expert on the bidirectional relationship between nutrition and sleep. We discuss how even moderate sleep loss increases appetite, changes hunger-related hormones, and causes weight gain, even when calories are not increased. We also explain how meal timing and specific foods, like fiber, ginger, saturated fat, and various oils, affect sleep onset, sleep quality, and metabolism. Throughout the conversation, we discuss specific foods and diets that directly support weight loss, better sleep, and long-term cardiometabolic health.
Thank you to our sponsors
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Dr. Marie-Pierre St-Onge
Eat Better, Sleep Better (book): https://amzn.to/4uqgvq9
Timestamps
00:00:00 Marie-Pierre St-Onge
00:02:29 Sleep Loss & Appetite, Men vs Women
00:10:20 Sponsors: David & BetterHelp
00:12:39 Sleep Loss, Overeating & Cardiometabolic Health
00:21:56 Weight Gain & Sleep Loss, Tool: Informed Food Choices
00:27:59 Diet & Sleep, Insomnia; Tool: Mediterranean Diet, DASH Diet
00:33:25 Food Choices & Sleep Quality, Food Timing
00:39:33 Sponsor: AG1
00:40:52 Personal Circadian Clock, Shift Work; Naps; Running & Yoga
00:53:00 Snoring, Sleep Apnea & Testing
00:56:46 Kefir; Coffee Mannooligosaccharides & Weight Loss; Ginger; Fiber
01:09:49 Sponsor: Helix Sleep
01:11:23 Food Timing & Burning Fat, Tool: Early Meals
01:17:20 Medium-Chain Triglycerides (MCTs), Body Composition & Weight Loss
01:22:54 Tools: Eating for Sleep & Metabolism; Portion Size; Portfolio Diet
01:34:38 Corn Oil, Seed Oils & Processed Foods, Smoke Points
01:41:20 Industry-Sponsored Studies
01:50:41 Supplements, Whole Foods, Fiber
01:54:25 Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter
#hubermanlab #metabolichealth #health
Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

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