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Autophagy Interventions Like Rapamycin Show Promise for Extending Healthspan

A recent review by Ebata and Hansen (2026) consolidates evidence that dietary restriction, intermittent fasting, spermidine‑rich foods, exercise, sleep hygiene, and hormetic temperature stress all activate autophagy, a cellular recycling process linked to longer healthspan. In model organisms these interventions require core autophagy genes to extend lifespan, while human data remain limited.

One Drink Harms Health: Quit Alcohol Now
SocialApr 14, 2026

One Drink Harms Health: Quit Alcohol Now

Friends, stop drinking alcohol. Not cut back. Eliminate. > alcohol increases cortisol > disrupts REM sleep > accelerates epigenetic aging > shrinks hippocampal volume > elevates resting heart rate > raises inflammatory markers > impairs glucose metabolism for 16 hrs One drink does that.

By Bryan Johnson
Rory McIlroy’s Diet: High Protein
SocialApr 13, 2026

Rory McIlroy’s Diet: High Protein

If you want to fuel like Rory McIlroy, it’s actually pretty consistent with my recommendations as a registered dietitian and certified sports nutritionist. He prioritizes protein first (around 170–180g daily) to support muscle, recovery, and stable energy. Then he adds in...

By Wendi Irlbeck, MS, RDN, CISSN
Osteoporosis Exercise Scientist: The Lifting Protocol That Reduces Fractures by 78% Dr Belinda Beck
VideoApr 13, 2026

Osteoporosis Exercise Scientist: The Lifting Protocol That Reduces Fractures by 78% Dr Belinda Beck

The video features Dr. Belinda Beck, a bone‑densitometry expert, who challenges the long‑standing belief that osteoporosis patients cannot safely engage in heavy resistance exercise. She explains that mechanical loading, proven in animal studies, triggers a dose‑response in bone tissue, and...

By Simon Hill – The Proof
Optimize Fertility: Hormone Health, Testing, and Lifestyle Choices
SocialApr 13, 2026

Optimize Fertility: Hormone Health, Testing, and Lifestyle Choices

The new Huberman Lab episode is out: How Women Can Improve Their Fertility & Hormone Health | Dr. Natalie Crawford (@ncrawfordmd) 0:00 Natalie Crawford 2:26 Fertility as a Health Marker, Infertility 5:34 Perimenopause, Menopause, Hormone Replacement Theory 11:01 Sponsors: David & BetterHelp 13:35 Hormone Therapy,...

By Andrew Huberman – Huberman Lab
Skip Meals Around Sleep to Improve Metabolism
SocialApr 13, 2026

Skip Meals Around Sleep to Improve Metabolism

If you are struggling with the symptoms of metabolic issues, such as blood glucose fluctuations, high body fat percentage/inability to lose weight, low heart rate variability, high heart rate, etc., then it’s pretty likely you would benefit from not eating...

By Ben Greenfield
She Was Told MS Was Irreversible… Then She Walked Again
VideoApr 13, 2026

She Was Told MS Was Irreversible… Then She Walked Again

The Longevity Technology Unlocked podcast featured Dr. Terry Walls, a neurologist‑researcher who transformed her own secondary progressive multiple sclerosis (MS) from wheelchair‑bound to walking and biking by combining a rigorously designed paleo diet, targeted supplements, electrical muscle stimulation and strength...

By Longevity.Technology
30‑Minute Sauna Spike Boosts Immune Cells
SocialApr 13, 2026

30‑Minute Sauna Spike Boosts Immune Cells

Sauna bathing mobilizes circulating immune cells. A single 30-minute session at ~165°F (enough to elevate body temperature to 101°F) increased levels of several immune cells including lymphocytes and neutrophils for up to 30 minutes. This occurred in non-users and people who used...

By Rhonda Patrick, PhD
Calorie Cutting Lowers Epigenetic Age and Inflammaging Protein C3a
SocialApr 13, 2026

Calorie Cutting Lowers Epigenetic Age and Inflammaging Protein C3a

Caloric restriction (CR) slows aging in rodents. People who cut calories by 14% over 2 years had lower epigenetic ages of some tissues & inflammatory protein C3a, regardless of BMI. In mice, lowering C3a levels reduced inflammaging, especially in fat....

By David Sinclair, PhD
You're Not Tired. Your Mitochondria Are. The Estrogen Connection in Perimenopause No One Explains
VideoApr 13, 2026

You're Not Tired. Your Mitochondria Are. The Estrogen Connection in Perimenopause No One Explains

The video explains how declining estrogen during perimenopause triggers a cascade of mitochondrial dysfunction, leaving many women feeling a sudden loss of energy compared with men’s gradual decline. It frames mitochondria as cellular power plants whose efficiency depends on hormonal...

By High Performance Health
Boost Athletic Recovery: Nutrition-Optimized Sleep Workshop
SocialApr 13, 2026

Boost Athletic Recovery: Nutrition-Optimized Sleep Workshop

LAST CHANCE to register https://t.co/6Nswtdw8XP Can you improve sleep with nutrition? Learn how to optimise sleep for better recovery, adaptation and performance in sport. https://t.co/OaGTE28Goh

By Asker Jeukendrup, PhD
Systems Thinking Unlocks Leverage to Slow Aging
SocialApr 13, 2026

Systems Thinking Unlocks Leverage to Slow Aging

The breakthrough in longevity science is systems thinking. When we map how aging actually works, we gain leverage to slow it down. https://t.co/hheOmHsWX7

By Brett King
You Have 5 Years Left." She Proved Them Wrong - Twice! With Leslie Kenny
VideoApr 13, 2026

You Have 5 Years Left." She Proved Them Wrong - Twice! With Leslie Kenny

The episode of "Better with Dr. Stephanie" centers on spermidine, a naturally occurring polyamine, and its capacity to counteract the twelve hallmarks of aging. Host Dr. Stephanie Estima interviews Leslie Kenny, who survived multiple autoimmune diagnoses and a five‑year mortality...

By Dr. Stephanie Estima
South Korea Survey Shows 70% of Adults Lack Adequate Sleep, Sparking Mental‑Health Concerns
NewsApr 13, 2026

South Korea Survey Shows 70% of Adults Lack Adequate Sleep, Sparking Mental‑Health Concerns

The 2026 Korea Sleep Health Report, released by Simmons Korea and the Korean Society of Sleep Medicine, found that 69.2% of South Korean adults aged 19‑69 get less than seven hours of sleep per night. The study links heavy caffeine...

By Pulse
Vogue Highlights Walking as Simple Habit to Lower Cortisol and Boost Recovery
NewsApr 13, 2026

Vogue Highlights Walking as Simple Habit to Lower Cortisol and Boost Recovery

Vogue published a piece promoting daily walks as a habit that can lower cortisol, referencing Mel Robbins' assertion that walking solves 93% of problems. The article positions the activity as an affordable, science‑backed way for fitness enthusiasts to improve recovery...

By Pulse
Yoga Cuts Teen Gaming Addiction Risk in NIMHANS Study
NewsApr 13, 2026

Yoga Cuts Teen Gaming Addiction Risk in NIMHANS Study

Researchers at India's National Institute of Mental Health and Neurosciences (NIMHANS) reported that an eight‑week yoga program slashed core symptoms of Internet Gaming Disorder in 14‑ to 15‑year‑olds. The trial involved 120 adolescents split between yoga and conventional activities, with...

By Pulse
The Cellular Incinerator: How Interventions Like Rapamycin Hijack Autophagy to Hack Aging
BlogApr 13, 2026

The Cellular Incinerator: How Interventions Like Rapamycin Hijack Autophagy to Hack Aging

A recent review by Ebata and Hansen (2026) synthesizes evidence that dietary restriction, intermittent fasting, spermidine‑rich foods, exercise, sleep hygiene, and hormetic temperature stress all stimulate autophagy—a cellular recycling process linked to longer healthspan. In model organisms, these interventions require...

By Rapamycin News
Advanced Meditation Techniques Linked to Younger Brain Age During Sleep
NewsApr 13, 2026

Advanced Meditation Techniques Linked to Younger Brain Age During Sleep

Researchers measured sleep EEGs of 34 long‑term meditators and found their brains appeared biologically about six years younger than their chronological age. The younger brain age was driven by high‑amplitude bursts during light sleep, despite the meditators sleeping fewer hours...

By PsyPost
Whoop 5.0 Review: A Fitness Tracker Focused on Performance and Longevity
NewsApr 13, 2026

Whoop 5.0 Review: A Fitness Tracker Focused on Performance and Longevity

Whoop’s fifth‑generation band adds a two‑week battery, faster processor and a new Healthspan suite that estimates biological age. The device remains screenless, streaming all data to a subscription‑based app with three membership tiers—One, Peak and Life—priced from $199 to $359...

By CNET – Gaming
Time‑restricted Eating Cuts Glucose, Insulin Resistance, HbA1c
SocialApr 13, 2026

Time‑restricted Eating Cuts Glucose, Insulin Resistance, HbA1c

Efficacy of different types of intermittent fasting in improving glycemic control in adults with overweight or obesity: a systematic review and network meta-analysis "Compared with a CON, TRE resulted in a larger reduction in fasting glucose... insulin resistance... HbA1c..." https://t.co/Jq9EpoAy3u

By David Barzilai, MD PhD