🎯 Today's Biohacking Pulse
Statins Cut Frailty Risk by 24% in Older Veterans
A retrospective cohort study of 987,301 U.S. veterans aged 67 and older found that starting statin therapy was linked to a 24% lower incidence of frailty over an average 5.3‑year follow‑up. The analysis, published in the European Heart Journal, controlled for a broad range of health and demographic variables.
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Left-Handed DNA Tubes Double Cancer Drug Killing by Boosting Cell Uptake
Researchers in the lab of Cancer Center at Illinois (CCIL) member Xing Wang have discovered the influential role of structural chirality, or "handedness," of a DNA nanostructure to dictate cancer cell response to targeted therapeutics. The team's findings are reported in Advanced Materials.
Medical Xpress
Cleared to Run Again After an Injury? This 9-Step Plan Helps You Come Back Stronger Than Ever
Resist the urge to pick up where you left off. A structured progression will help you safely return to running and reduce the risk of setbacks along the way.
Runners World
New Research Helps Explain Rachel Entrekin’s Historic Cocodona 250 Win. Here’s What You Can Learn From the Findings.
It all comes down to durability.
Runners World
CRISPR Shreds Undruggable Cancer Cells with Precision
“Guardian of the genome,” p53 is now therapeutically accessible using CRISPR-based technology from Jennifer Doudna’s lab. The approach uses RNA signatures to identify and destroy traditionally undruggable cancer cells. The post CRISPR Shreds Undruggable Cancer Cells with Precision appeared first on GEN - Genetic Engineering and Biotechnology News.
GEN (Genetic Engineering & Biotechnology News)
Low Dose Continuous Rapamycin Favorably Alters the Aging Immune System
Rapamycin is an immunosuppressant long used in transplant medicine at relatively high doses. At lower doses, it slows aging and extends life in animal studies by mimicking some of the beneficial metabolic reactions to calorie restriction, such as increased autophagy. A fair number of people use rapamycin with the hopes of achieving the same outcome, though the human data for this use case and dosage remains sparse. Normally rapamyin is taken once a week, but here researchers mix it in with the diet in a study of immune aging in mice. Aging is the gradual accumulation of structural and functional changes in an organism over time, including immune remodeling and a progressive increase in basal inflammation, or inflammaging. The mTOR pathway is a central driver […]
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Thread by @Tomnutritionist
Biotic supplements improve sleep in athletes 💤 This new meta-analysis compiled data from 6 studies (180 participants) to establish the effects of probiotic and synbiotic supplementation on sleep in athletes 🔍 Here is what they found ⬇️ 🗓️ Interventions lasted 4 - 17 weeks 😴 Overall, 9 of 12 sleep parameters were improved with biotic supplementation Benefits were most consistent for… 💤 subjective sleep quality ⏱️ sleep latency Secondary outcomes showed occasional reductions in… ✅ stress
Tweet by @SandCResearch
Sleep loss is known to affect workout performance negatively. It does this by increasing pain sensitivity, which reduces our ability to produce maximum levels of motor unit recruitment by reducing the maximum tolerable perception of effort. https://t.co/n3hOSrmXE4