Fujifilm Biotechnologies Opens New QC Lab in Denmark
Fujifilm Biotechnologies has opened a 2,000‑square‑meter GMP‑approved quality control laboratory at its Hillerød, Denmark site. The facility, designed for bioassay and virology work, will accommodate roughly 100 quality‑team members and features robotics, airlocks and a new LIMS for digital data integrity. It expands the QC footprint to match the plant’s recent capacity boost to twelve 20,000‑liter bioreactors. Operations are slated to begin in May 2026 after Danish Medicines Agency approval.
Digital Twin Process Could Slash Microbial Protein Costs
A consortium led by Novasign has built an end‑to‑end digital twin of the microbial protein production process, promising to cut experimental runs by roughly 70% compared with traditional design‑of‑experiments approaches. The model spans upstream to downstream steps, offering real‑time deviation...
Ultra- and Diafiltration Clear Leachables Effectively
A new study from the National Institute for Bioprocessing Research demonstrates that ultrafiltration and diafiltration (UF/DF) consistently remove over 98% of 24 out of 28 tested leachable compounds across three distinct protein processes. The clearance is largely driven by the...
IPSC-Based Manufacture Vs. Autologous Model Production Costs Examined via Financial Analysis
A new Cellistic white paper quantifies the cost advantage of using induced pluripotent stem cells (iPSCs) to manufacture NK cell therapies. The analysis shows cost of goods per dose can drop to roughly $5,000, a 95% reduction compared with $115,000...
Biopharma Adopting AI Despite Remaining GMP Compliance Questions
Biopharma firms are rapidly integrating artificial intelligence and machine learning into manufacturing, but regulatory‑compliant use cases remain a hurdle. Thermo Fisher’s senior director emphasizes that AI should augment, not replace, validated processes and must operate within a clear GMP framework....
Novel Targets for Complex Cancer Revealed by Genetic Regulatory Node Mapping
Researchers at Rockefeller University unveiled PerturbFate, a single‑cell platform that maps how diverse genetic variations reshape cellular behavior over time. By profiling DNA accessibility, RNA output, and chromatin state in thousands of cells, the system identified common regulatory nodes that...
CAR T Cell Therapy Biomanufactured by Cellares Infused Into First Two Patients
Cellares has successfully infused the first two patients with rese‑cel, Cabaletta Bio’s investigational autologous CAR‑T therapy, using its automated Cell Shuttle manufacturing platform. The product met all GMP release criteria, demonstrating that a low‑cost, high‑capacity process can produce clinical‑grade cell...
GLP-1 Drug Improves Liver Health Independent of Weight Loss, Mouse Study Finds
Researchers at Toronto’s Sinai Health discovered that semaglutide, a GLP‑1 agonist, improves liver function by acting directly on liver sinusoidal endothelial cells, independent of weight loss. The study, published in Cell Metabolism, used mouse models of metabolic dysfunction‑associated steatohepatitis (MASH)...
From Colossal to Chickens: The Scientists Behind Neion Bio’s Biologics Platform
Neion Bio, founded by Dimi Kellari and Sam Levin, is developing a chicken‑based platform that inserts therapeutic proteins into the ovalbumin gene so that eggs become biologic factories. The company recruited former Colossal Biosciences veterans Sven Bocklandt (CSO) and James...
Sex-Related Differences in Immune System Aging May Impact Disease Susceptibility
Researchers at Barcelona Supercomputing Center used single‑cell RNA sequencing on nearly 1,000 blood samples to map how immune aging differs between men and women. The analysis revealed that women experience a pronounced increase in inflammatory immune cells with age, which...
Salk to Lead $41.3M ARPA-H Effort to Advance Sonogenetics Therapies
The Salk Institute secured a $41.3 million ARPA‑H award to advance sonogenetics, a technique that uses low‑intensity ultrasound to control engineered cellular proteins. Over the next five years, Salk’s Dr. Sreekanth Chalasani and a multi‑institutional team will develop ultrasound‑responsive proteins, wearable...
AACR 2026: Professional Awards Acknowledge Community’s Contributions to Cancer Research
The American Association for Cancer Research unveiled its 2026 professional award winners at the San Diego meeting (April 17‑22). Honorees span the spectrum of oncology, from James P. Allison’s seminal CTLA‑4 work to the Broad Institute’s Cancer Dependency Map team that charted...
Advancing Fully Walkaway Automation in Genomics Workflows
SPT Labtech and the European Molecular Biology Laboratory’s GeneCore facility in Heidelberg have partnered to install the firefly®+ all‑in‑one liquid‑handling platform, aiming to deliver fully walkaway automated genomics workflows. The system combines pipetting, dispensing, incubation and shaking, and will run...
StockWatch: IPO Market Shows Sign of Life with Avalyn Filing
Avalyn Pharma, a Boston‑based biotech, filed an S‑1 on Wednesday seeking up to $100 million to advance its inhaled antifibrotic pipeline for pulmonary fibrosis. The filing marks the first biotech IPO since Generate: Biomedicines raised $400 million and revives a market that...
First Detailed Insight Into Bornavirus Nucleoprotein–RNA Complex Reveals Unique Assembly
Researchers from Kyoto, Osaka Dental, and Osaka Metropolitan Universities used cryo‑electron microscopy to obtain the first high‑resolution structure of the Borna disease virus 1 (BoDV‑1) nucleoprotein‑RNA complex. The study revealed ring‑like assemblies where each nucleoprotein subunit binds eight RNA nucleotides,...
