Nature Neuroscience - Latest News and Information
Researchers recorded hundreds of neurons in the medial entorhinal cortex (MEC) and hippocampal CA1 of mice performing a spatial match‑to‑sample task. They found that during immobility the MEC population frequently decoded positions far from the animal, a phenomenon termed non‑local coding, which occurred in roughly half of immobility bouts and lasted about 270 ms. This remote representation was independent of CA1 sharp‑wave ripples and preferentially reflected task‑relevant reward locations. The findings suggest MEC can encode spatial associations without hippocampal coordination.
Researchers recorded dorsal (dHPC) and ventral (vHPC) hippocampal neurons in rats performing rewarded and aversive runs, then examined sleep periods. They found that neural assemblies from both regions reactivate strongly during early post‑sleep, with reactivation rates returning to baseline later....
The study reveals that medial prefrontal cortex (dmPFC) ensembles encode collective social variables such as huddle size, membership, and active versus passive entry decisions in mice facing cold stress. Using a custom SLEAP‑based multi‑animal pose‑tracking pipeline and calcium imaging, the...
Researchers built a whole‑brain atlas of 38 neuropeptide‑receptor genes, mapping their expression across 455 cortical, subcortical and hypothalamic regions. The receptors display a clear cortical‑subcortical gradient and two principal axes within hypothalamic nuclei that reflect developmental organization. Spatial overlap analysis...
Researchers used a 3‑T MRI‑compatible deep brain stimulation system to record extensive functional MRI data from 14 Parkinson’s disease patients over a year. Each participant completed 11.7 hours of fMRI across seven stimulation conditions at five longitudinal visits, alongside structural and...
