Research Square – News/Updates

Research Square – News/Updates

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Navigating the Quantum Resource Landscape of Entropy Vector Space Using Machine Learning and Optimization
NewsApr 3, 2026

Navigating the Quantum Resource Landscape of Entropy Vector Space Using Machine Learning and Optimization

A new preprint introduces a machine‑learning framework that maps entropy‑vector dynamics to identify quantum states violating Ingleton’s inequality, a boundary respected by stabilizer and holographic states. The authors prove pure‑state violations are impossible for five qubits or fewer, establishing six...

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Machine Learning-Based Prediction of SARS-CoV-2 Bioactivity: Integrating IC50 Regression and Activity Classification Using Multi-Task Neural Networks
NewsApr 3, 2026

Machine Learning-Based Prediction of SARS-CoV-2 Bioactivity: Integrating IC50 Regression and Activity Classification Using Multi-Task Neural Networks

Researchers introduced an integrated machine‑learning framework to predict SARS‑CoV‑2 compound potency. The system combines an IC50 regression model, a binary activity classifier, and a multi‑task neural network that performs both tasks simultaneously. Incorporating ligand efficiency as a classification criterion, the...

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Factors Associated with SARS-CoV-2 Infection Among Healthcare Workers: A European Multicentre Cohort Study, May 2021–April 2024
NewsApr 3, 2026

Factors Associated with SARS-CoV-2 Infection Among Healthcare Workers: A European Multicentre Cohort Study, May 2021–April 2024

A European multicentre cohort of 18 hospitals tracked 4,705 healthcare workers from May 2021 to April 2024, dividing the data into pre‑Omicron, Omicron, and post‑Omicron periods. The analysis revealed that ancillary personnel faced the highest infection risk before Omicron (aHR 3.86) and that...

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Effect of Zero-Valent Iron Activated Sodium Hypochlorite on Sludge Dewatering Performance
NewsApr 3, 2026

Effect of Zero-Valent Iron Activated Sodium Hypochlorite on Sludge Dewatering Performance

Researchers evaluated zero‑valent iron (ZVI) activated sodium hypochlorite (NaClO) as a sludge conditioning agent. Under optimal acidic conditions (pH 3, 75 mg Fe per g dry solids, 100 mg NaClO per g dry solids) the capillary suction time fell from 192.7 s to 51.3 s...

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City Birds Are Smaller but Noisier: Morphology, Body Condition, and Song Variation Between Rufous-Collared Sparrows (Zonotrichia Capensis) From Urban and...
NewsApr 2, 2026

City Birds Are Smaller but Noisier: Morphology, Body Condition, and Song Variation Between Rufous-Collared Sparrows (Zonotrichia Capensis) From Urban and...

A recent study of Rufous‑collared Sparrows (Zonotrichia capensis) in central Chile compared individuals from urban and wild habitats. Researchers measured 34 urban and 64 wild birds, documenting morphology and song during the breeding season. Urban birds were significantly smaller, lighter,...

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Development And Validation Of Prognostic Scale In Respiratory Condition for Physiotherapist in ICU
NewsApr 1, 2026

Development And Validation Of Prognostic Scale In Respiratory Condition for Physiotherapist in ICU

Researchers have designed and validated a prognostic scale tailored for physiotherapists treating respiratory conditions in intensive care units. The scale achieved a content validity ratio of 0.846, indicating strong reliability, while Cohen’s kappa testing demonstrated perfect inter‑rater agreement (p < 0.05). Validation...

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Phenotypic Behaviour and Association Analysis of Agronomic Traits, Proximate, Nutrients and Quality Attributes of West Africa
NewsApr 1, 2026

Phenotypic Behaviour and Association Analysis of Agronomic Traits, Proximate, Nutrients and Quality Attributes of West Africa

A study of 21 West African okra accessions revealed extensive genetic variability in yield, protein, fiber, zinc, ash and viscosity. Genotypes OK18, OK14 and OK17 delivered the highest fruit yields, while OK3, OK5 and OK6 excelled in protein, ash and...

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Impact of Subsidy Modes on Herders&rsquo; Grassland Carbon Sink Investment Strategies: Resource Allocation Theory
NewsApr 1, 2026

Impact of Subsidy Modes on Herders&rsquo; Grassland Carbon Sink Investment Strategies: Resource Allocation Theory

The paper applies resource‑allocation theory to evaluate how different subsidy policies affect herders’ decisions between grazing and grassland carbon‑sink investment. Three optimisation models—no‑subsidy, carbon‑sink revenue subsidy, and grazing‑product subsidy—are compared across constraint scenarios. Results show that carbon‑sink revenue subsidies encourage...

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Autonomous Atomic-Scale Self-Healing in Two-Dimensional MXenes via Diffusion-Driven Lattice Reconstruction
NewsApr 1, 2026

Autonomous Atomic-Scale Self-Healing in Two-Dimensional MXenes via Diffusion-Driven Lattice Reconstruction

Researchers used in‑situ scanning transmission electron microscopy to capture the first intrinsic self‑healing events in two‑dimensional MXenes, occurring without external stimuli. Nanopores created in titanium‑carbide (Ti‑C) and medium‑entropy MXenes closed spontaneously at room temperature, and heating to 250 °C and 500 °C...

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Endogenous Glandular Chemistry and Methyl Eugenol–Derived Metabolites in the Pheromone Communication of Bactrocera Umbrosa
NewsApr 1, 2026

Endogenous Glandular Chemistry and Methyl Eugenol–Derived Metabolites in the Pheromone Communication of Bactrocera Umbrosa

Researchers decoded the pheromone system of the fruit fly Bactrocera umbrosa, identifying four endogenous volatiles in immature males and six additional compounds in mature males, including two previously unknown diols. After feeding on methyl eugenol, males accumulated six specific metabolites....

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Design of Polyvinyl Alcohol/Bacterial Cellulose/Sodium Alginate/MXene@Polydopamine Hydrogel Evaporator for Fresh Water Acquisition
NewsApr 1, 2026

Design of Polyvinyl Alcohol/Bacterial Cellulose/Sodium Alginate/MXene@Polydopamine Hydrogel Evaporator for Fresh Water Acquisition

Researchers have engineered a physically cross‑linked multi‑network hydrogel combining polyvinyl alcohol, sodium alginate and bacterial cellulose, reinforced with MXene@Polydopamine photothermal particles. The resulting evaporator delivers a high solar‑driven evaporation rate while maintaining cyclic stability and salt tolerance. Laboratory tests show...

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A Longitudinal Multi‑proxy Geospatial Classification of Peri‑urban Transitions Across Community Health Units in Coastal Kenya
NewsApr 1, 2026

A Longitudinal Multi‑proxy Geospatial Classification of Peri‑urban Transitions Across Community Health Units in Coastal Kenya

The study applied five publicly available geospatial proxies to classify settlement dynamics across ten Community Health Units in coastal Kenya from 2017 to 2024. Median cumulative changes were 62% for nighttime lights, 111% for Sentinel‑2 built‑up, 34% for WorldPop built‑up,...

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Adaptive Mesh Refinement (H-Adaptive FEM) for High-Fidelity Thermal Simulation of Microchip Cooling Systems
NewsApr 1, 2026

Adaptive Mesh Refinement (H-Adaptive FEM) for High-Fidelity Thermal Simulation of Microchip Cooling Systems

The paper introduces an h‑adaptive finite element method for solving the two‑dimensional Poisson equation in microchip thermal analysis. By employing a nodal‑based a‑posteriori error estimator, the mesh automatically refines around high‑power components, capturing steep temperature gradients with linear triangular (P1)...

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Structural Controls and Mineralization Style of Baryte Deposits in the Azara Area, Central Benue Trough, Nigeria: Implications for Mineral Exploration
NewsApr 1, 2026

Structural Controls and Mineralization Style of Baryte Deposits in the Azara Area, Central Benue Trough, Nigeria: Implications for Mineral Exploration

Baryte mineralization in Nigeria’s Azara area of the central Benue Trough is hosted primarily in Cretaceous siliciclastic rocks and is tightly linked to a NE‑SW structural corridor that coincides with an anticlinal crest. Integrated surface mapping, satellite‑image processing, airborne radiometric...

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Investigation of the Element Content of Black Shale Samples by INAA and EDXRF
NewsApr 1, 2026

Investigation of the Element Content of Black Shale Samples by INAA and EDXRF

Researchers measured more than 50 elements in two black shale reference materials (SChS‑1A and SLg‑1A) using instrumental neutron activation analysis (INAA) and energy‑dispersive X‑ray fluorescence (EDXRF). Nine parallel 100 mg aliquots were analyzed, yielding mean values and 95 % confidence intervals with...

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Structural and Genetic Analysis of Neutralizing Antibodies Reveals Mechanisms of GII.4 Norovirus Antigenic Evolution
NewsMar 31, 2026

Structural and Genetic Analysis of Neutralizing Antibodies Reveals Mechanisms of GII.4 Norovirus Antigenic Evolution

Researchers solved the atomic structures of two neutralizing monoclonal antibodies against the pandemic GII.4 norovirus, targeting the principal antigenic sites A and G. The spatial positioning of site G was shown to shape neutralizing responses, while coordinated substitutions within these...

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The Infrastructure Paradox of AI Development in LMICs
NewsMar 31, 2026

The Infrastructure Paradox of AI Development in LMICs

A new cross‑sectional study of 91 AI practitioners across 27 low‑ and middle‑income countries uncovers an “Infrastructure Paradox” where the regions most poised to benefit from AI lack the foundational resources to develop it. The research identifies three non‑linear dynamics:...

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Fracture Characteristics From Well Flowrate Fluctuations: A Statistical Physics Approach
NewsMar 31, 2026

Fracture Characteristics From Well Flowrate Fluctuations: A Statistical Physics Approach

Researchers propose a statistical‑physics framework that treats well flow‑rate fluctuations as a proxy for subsurface strain changes. By applying Jaynes' maximum entropy principle with energy‑input constraints, they link covariance of inter‑well flow noise to non‑local stiffness tensors. This relationship enables...

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Impact of Energy Disruptions on Agri-Food Supply Chains
NewsMar 31, 2026

Impact of Energy Disruptions on Agri-Food Supply Chains

A blockade of the Strait of Hormuz has sparked a global oil supply shock that reverberates through agricultural and food supply chains in India, Pakistan, and the Philippines. Using the hypothetical extraction method and Asian Development Bank input‑output tables, researchers...

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Channel Pattern Morphology of the Bhagirathi Hooghly River Using GIS Techniques
NewsMar 31, 2026

Channel Pattern Morphology of the Bhagirathi Hooghly River Using GIS Techniques

A GIS‑based study examined the 486.5 km stretch of the Bhagirathi‑Hooghly River, dividing it into eight reaches to compute key geomorphological indices. The river displays a Braiding Index of 0.82 and a Sinuosity Index of 1.50, indicating moderate braiding alongside pronounced...

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Clinical Efficacy of Low-Level Laser Therapy as an Adjunct to Non-Surgical Treatment of Peri-Implantitis: A Systematic Review and Meta-Analysis
NewsMar 31, 2026

Clinical Efficacy of Low-Level Laser Therapy as an Adjunct to Non-Surgical Treatment of Peri-Implantitis: A Systematic Review and Meta-Analysis

A systematic review and meta‑analysis of 15 randomized trials involving 644 patients and 742 implants examined low‑level laser therapy (LLLT) and antimicrobial photodynamic therapy (aPDT) as adjuncts to non‑surgical debridement for peri‑implantitis. The analysis found modest but statistically significant reductions...

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Comparison of Capillary Microsampling and Venous Blood for Multi-Pathogen Serosurveillance
NewsMar 31, 2026

Comparison of Capillary Microsampling and Venous Blood for Multi-Pathogen Serosurveillance

A pre‑print study compared capillary dried blood spot (DBS) microsampling—including filter‑paper punches and Mitra volumetric absorptive microsamplers—with venous plasma for multiplex serosurveillance of seven vaccine‑preventable diseases. The analysis showed strong agreement for six pathogens, with ≥93% of paired measurements within...

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Predicting Mental Health Treatment Seeking in the Technology Industry Using Machine Learning: A Comparative Analysis of Supervised Classification Models
NewsMar 31, 2026

Predicting Mental Health Treatment Seeking in the Technology Industry Using Machine Learning: A Comparative Analysis of Supervised Classification Models

Researchers applied five supervised machine learning models to the 2016 OSMI survey of tech workers to predict mental health treatment seeking. XGBoost delivered the top accuracy at 88.7%, slightly ahead of Random Forest and Logistic Regression. Prior diagnosis and family...

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The Early-Universe Dust Formation Crisis: A StochasticThreshold Solution
NewsMar 29, 2026

The Early-Universe Dust Formation Crisis: A StochasticThreshold Solution

Observations of massive dust reservoirs in high‑redshift galaxies clash with traditional, slow dust‑production theories. Researchers introduced a stochastic, non‑equilibrium model that couples gas, metals, and dust across diffuse, cold, and molecular phases, incorporating burst‑driven star formation and time‑delay effects. A...

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Stability of Immature Platelets Present in Single Donor Units During Hemoconcentration
NewsMar 28, 2026

Stability of Immature Platelets Present in Single Donor Units During Hemoconcentration

The study examined how routine plasma‑reduction and centrifugation affect immature platelets in single‑donor units. Centrifugation increased platelet concentration per milliliter, while total counts of both platelets and immature platelets remained unchanged. The ratio of immature to mature platelets and their...

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A Latent Profile Analysis of Prenatal Depression and Anxiety in Chinese Women with Twin Pregnancies
NewsMar 28, 2026

A Latent Profile Analysis of Prenatal Depression and Anxiety in Chinese Women with Twin Pregnancies

A cross‑sectional study of 334 Chinese women carrying twins applied latent profile analysis to uncover distinct patterns of prenatal depression and anxiety. Researchers identified two subgroups: a low‑risk group comprising 65% of participants and a high‑risk group representing 35%. Multivariate...

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Validation of the First Brazilian Instrument for Patient Engagement in Patient Safety
NewsMar 28, 2026

Validation of the First Brazilian Instrument for Patient Engagement in Patient Safety

Researchers have produced a Brazilian Portuguese version of the Patient Engagement in Patient Safety tool, adapting it through a six‑step cross‑cultural process and validating it with a Delphi panel of seven experts. The adaptation achieved 97.9% item equivalence, while content...

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Assessment of Caregiver Burden Amongst Parents of Children With Congenital Heart Disease in Two Tertiary Hospitals in Nigeria: A Cross-...
NewsMar 28, 2026

Assessment of Caregiver Burden Amongst Parents of Children With Congenital Heart Disease in Two Tertiary Hospitals in Nigeria: A Cross-...

A cross‑sectional study of 100 primary caregivers at two Nigerian tertiary hospitals measured caregiver burden among parents of children with congenital heart disease (CHD). The research found that 41% of caregivers experienced moderate burden and 26% severe burden, with emotional/psychological...

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Manual Pressure Techniques Activate Descending Pain-Modulatory Pathways and Reduce Headache Intensity in Chronic Tension-Type Headache: A Randomized Crossover Trial
NewsMar 28, 2026

Manual Pressure Techniques Activate Descending Pain-Modulatory Pathways and Reduce Headache Intensity in Chronic Tension-Type Headache: A Randomized Crossover Trial

A randomized crossover trial involving 37 chronic tension‑type headache patients found that manual pressure techniques and the cold pressor test both elevated pressure pain thresholds, indicating activation of descending pain‑modulatory pathways. However, only manual pressure produced a statistically significant reduction...

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Psychological Empowerment as a Moderator in the Pathway From Attitudes Toward Care of the Dying to Palliative Care Competency Among...
NewsMar 28, 2026

Psychological Empowerment as a Moderator in the Pathway From Attitudes Toward Care of the Dying to Palliative Care Competency Among...

A cross‑sectional survey of 996 nursing interns from 42 Chinese teaching hospitals examined how attitudes toward caring for the dying influence palliative care competence. The study found a strong positive effect (β = 0.594) and identified self‑efficacy and psychological resilience as sequential...

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Real-World Patterns of Peri-Procedural Antiplatelet Therapy and Concomitant Verapamil Use During Transradial Percutaneous Coronary Intervention
NewsMar 28, 2026

Real-World Patterns of Peri-Procedural Antiplatelet Therapy and Concomitant Verapamil Use During Transradial Percutaneous Coronary Intervention

A single‑center retrospective study of 204 transradial PCI cases (2024‑25) found verapamil used in 98.5% of procedures. Ticagrelor was administered in 33.3% of cases, and 97.1% of ticagrelor patients also received verapamil, yielding an overall co‑exposure rate of 32.4%. Ticagrelor...

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The Utilisation of Endocrine and Immunotherapy: Retrospective Study at a Tertiary Hospital in South Africa
NewsMar 28, 2026

The Utilisation of Endocrine and Immunotherapy: Retrospective Study at a Tertiary Hospital in South Africa

A retrospective study of 82 cancer patients at a Limpopo tertiary hospital found endocrine therapy used as first‑line or adjuvant treatment in 29.3% of cases, while immunotherapy was virtually absent, administered to only five patients overall. Significant associations emerged between...

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Normative Values of Evans&rsquo; Index and Cranial Dimensions on Brain CT Scans: Age- and Sex-Related Variations in a Southeastern Nigerian...
NewsMar 28, 2026

Normative Values of Evans&rsquo; Index and Cranial Dimensions on Brain CT Scans: Age- and Sex-Related Variations in a Southeastern Nigerian...

A retrospective analysis of 676 normal cranial CT scans from a southeastern Nigerian hospital established age‑ and sex‑specific normative values for Evans’ Index (EI). The overall median EI was 0.28 with a 95 % range of 0.22–0.32, and EI rose steadily...

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Geology and Depositional Characteristics of Early-Middle Miocene Fossil Woods (Central T&uuml;rkiye)
NewsMar 28, 2026

Geology and Depositional Characteristics of Early-Middle Miocene Fossil Woods (Central T&uuml;rkiye)

The study maps Early‑Middle Miocene silicified wood fossils within the Galatian Volcanic Complex (GVC) of central Turkey, pinpointing seven localities where the woods occur in stratified, scattered, or tightly packed horizons. These fossils are embedded in fine‑grained pyroclastic and sedimentary...

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Dynamic Modeling of a Standard Internal Tool Holder
NewsMar 28, 2026

Dynamic Modeling of a Standard Internal Tool Holder

The study presents a three‑span Euler‑Bernoulli model of an internal turning boring bar with free‑pinned‑pinned‑free constraints, deriving its characteristic equation via Krylov‑Duncan functions. Numerical calculations reveal the first natural frequencies and mode shapes, highlighting how overhang length and boundary conditions...

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CUVAE: Strengthening Latent Representations in Skip-Connection VAEs for High-Fidelity Medical Image Reconstruction
NewsMar 28, 2026

CUVAE: Strengthening Latent Representations in Skip-Connection VAEs for High-Fidelity Medical Image Reconstruction

The paper introduces CUVAE, a Constrained Unfolding Variational Autoencoder that adds weighted skip‑connections and batch‑normalized latent constraints to traditional VAEs. By addressing posterior collapse, CUVAE preserves a structured latent space while maintaining high‑fidelity image reconstruction. Experiments on Chest X‑ray (Pneumonia)...

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Digital Health Divide and Its Impact on Access to Preventive Healthcare Services in Urban India
NewsMar 27, 2026

Digital Health Divide and Its Impact on Access to Preventive Healthcare Services in Urban India

A cross‑sectional study of 1,482 adults in Hyderabad found that 58.7% enjoy high digital health access while 41.3% do not. Those with low digital access are far less likely to use preventive healthcare services (32.4% vs 68.9%). Multivariate analysis links...

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A Precision Epigenetic Approach to Non-Invasive Lung Cancer Screening Using Gene- Specific cfDNA Methylation
NewsMar 27, 2026

A Precision Epigenetic Approach to Non-Invasive Lung Cancer Screening Using Gene- Specific cfDNA Methylation

A recent study demonstrates that promoter methylation of four genes—MAX, MTURN, HLA‑B and CAV1—can be detected in plasma circulating cell‑free DNA and used as a non‑invasive biomarker for lung cancer. In tumor tissue, MAX, MTURN and HLA‑B showed hypermethylation rates...

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Multi-Objective AI-Driven Optimization Guides the Discovery of High-Performance Organic Photovoltaics
NewsMar 27, 2026

Multi-Objective AI-Driven Optimization Guides the Discovery of High-Performance Organic Photovoltaics

Researchers unveiled a closed‑loop, multi‑objective Bayesian optimization workflow that streamlines the discovery of high‑performance organic photovoltaics. By navigating an eight‑dimensional space of composition and fabrication variables—covering roughly 2.2 × 10¹⁴ possible formulations—the system identified a power conversion efficiency above 20% in just...

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Low Climatic Niche Overlap Among Allopatric Woolly Opossum Species Reflects Phylogenetic and Geographic Influences in the Neotropics
NewsMar 27, 2026

Low Climatic Niche Overlap Among Allopatric Woolly Opossum Species Reflects Phylogenetic and Geographic Influences in the Neotropics

Researchers examined climatic niche overlap among three Neotropical marsupial species of the genus Caluromys using 1,158 cleaned occurrence records and 19 WorldClim bioclimatic variables. Contrary to expectations of high similarity, the analysis revealed generally low niche overlap, with the pair...

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Batten Disease with Narcolepsy and Functional Neurological Disorder: A Case Report
NewsMar 27, 2026

Batten Disease with Narcolepsy and Functional Neurological Disorder: A Case Report

Researchers report the first documented case of a 17‑year‑old with juvenile Batten disease (CLN3) who also developed functional neurological disorder and narcolepsy. Video‑EEG confirmed functional seizures, while Multiple Sleep Latency Testing diagnosed narcolepsy, and treatment with armodafinil dramatically reduced seizure...

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Global Research Trends in Robot-Assisted and 3D Printing Technologies for Total Knee Arthroplasty: An Analysis Based on Bibliometrics and Knowledge...
NewsMar 26, 2026

Global Research Trends in Robot-Assisted and 3D Printing Technologies for Total Knee Arthroplasty: An Analysis Based on Bibliometrics and Knowledge...

A bibliometric analysis of 180 papers from 2000‑2025 maps the rise of robot‑assisted and 3D‑printing technologies in total knee arthroplasty (TKA). Publication volume accelerated after 2016, with robotic systems leading the field while 3D printing expands into pre‑operative planning, guide‑plate...

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Associations of Racial Discrimination with Resting-State Network Topology: A Mechanism for Post-Traumatic Sensory Disruptions
NewsMar 26, 2026

Associations of Racial Discrimination with Resting-State Network Topology: A Mechanism for Post-Traumatic Sensory Disruptions

A new resting‑state fMRI study of 90 Black American women links higher exposure to racial discrimination with reduced clustering coefficient in the somatomotor network (SMN). This decrease in SMN clustering was found to amplify PTSD re‑experiencing symptoms, but only when...

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Pan-Cancer Variance Decomposition Nominates Translationally Actionable Therapeutic Antigen Candidates Across 33 Cancer Types
NewsMar 26, 2026

Pan-Cancer Variance Decomposition Nominates Translationally Actionable Therapeutic Antigen Candidates Across 33 Cancer Types

Researchers applied a genome‑wide variance decomposition across TCGA’s 60,656 genes and 33 cancer types to prioritize therapeutic antigens, moving beyond traditional mean‑expression screens. The analysis yielded 17 candidates that met functional dependency, safety, and immune‑cold criteria, with three highlighted: CRIPTO/TDGF1,...

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Identification of Crucial Genes and Biological Pathways in Lung Adenocarcinoma by Network Pharmacology, Molecular Docking, and Simulation Studies
NewsMar 26, 2026

Identification of Crucial Genes and Biological Pathways in Lung Adenocarcinoma by Network Pharmacology, Molecular Docking, and Simulation Studies

Researchers applied network pharmacology, molecular docking, and molecular dynamics to assess bioactive compounds from Pleurotus membranaceus for lung adenocarcinoma therapy. Four compounds passed drug‑likeness filters, linking to 226 overlapping disease targets and highlighting five hub genes. Docking showed isosorbide binding...

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Multi-Scenario Land Use Change and Its Effects on Ecosystem Service Value and Ecological Compensation in the Middle Yangtze River
NewsMar 26, 2026

Multi-Scenario Land Use Change and Its Effects on Ecosystem Service Value and Ecological Compensation in the Middle Yangtze River

A new study applied high‑resolution land‑use data (2000‑2020) and the PLUS simulation model to project 2030 land‑use dynamics for the Middle Yangtze River Urban Agglomeration under four scenarios. The Business‑as‑Usual, Economic Development Priority, Ecological Protection Priority, and Ecological‑Economic Balance pathways...

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A Hybrid CNN–Transformer Network to EnhanceSolar Magnetogram Resolution for Flare PredictiveAnalytics
NewsMar 26, 2026

A Hybrid CNN–Transformer Network to EnhanceSolar Magnetogram Resolution for Flare PredictiveAnalytics

Researchers introduced MagRes‑Net, a hybrid convolutional neural network and transformer architecture that upscales low‑resolution SOHO/MDI magnetograms to match the detail of SDO/HMI observations. Trained on co‑aligned MDI‑HMI image pairs with physics‑aware constraints, the model restores fine magnetic structures while conserving...

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Stereoelectroencephalography in the Presurgical Evaluation of Drug–Resistant Epilepsy: Retrospective Analysis of Clinical Efficacy and Safety in 71 Procedures
NewsMar 26, 2026

Stereoelectroencephalography in the Presurgical Evaluation of Drug–Resistant Epilepsy: Retrospective Analysis of Clinical Efficacy and Safety in 71 Procedures

A retrospective review of 71 drug‑resistant epilepsy patients undergoing stereoelectroencephalography (SEEG) showed that the technique confirmed the pre‑implantation hypothesis in 85% of cases. SEEG‑guided radiofrequency thermocoagulation (RF‑TC) was performed in 52% of patients, yielding seizure improvement in 73% at 12...

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Phenylalanine-Associated Ocular Risk Stratification in Early-Treated Children with Phenylketonuria: A Cross-Sectional Study
NewsMar 26, 2026

Phenylalanine-Associated Ocular Risk Stratification in Early-Treated Children with Phenylketonuria: A Cross-Sectional Study

A cross‑sectional study of 33 early‑treated PKU children found ocular abnormalities common, linked to higher serum phenylalanine. Comprehensive eye exams revealed anterior and posterior segment issues. ROC analysis defined phenylalanine thresholds that predict elevated ocular risk. Findings suggest metabolic control...

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