Latency-Aware Optimization of Backend Interactions in Microservices-Based Architectures
A new integrated ship navigation guidance system leverages data‑mining to extract key navigation and environmental information. Adaptive K‑means clustering identifies critical features, while an enhanced genetic algorithm generates optimal, obstacle‑aware routes. The system presents real‑time guidance through an intuitive human‑computer interface, enabling safer, more reliable voyages. Experimental trials confirm improved route efficiency and reduced collision risk.
Semantic-Aware Decoding of Covert Inner Speech: A Multimodal EEG–EMG–Audio Framework
Researchers introduced a multimodal EEG‑EMG framework that learns semantic representations from overt speech to decode covert inner‑speech commands. Ten participants uttered four everyday commands, providing synchronized EEG, EMG and audio for overt trials and EEG‑EMG only for covert trials. Using...
Efficient Optimization of Large Language Models via Parameter-Efficient Tuning and Adaptive Inference
The paper introduces a unified framework that merges data‑centric learning, parameter‑efficient fine‑tuning, and adaptive inference to streamline large language model (LLM) optimization. By targeting scalability and computational cost, the method trims memory footprints and accelerates inference without sacrificing accuracy. Experimental...
Effect of Seed Layers on the Growth of Novel 3D TiO 2 Nanorod Thin Films by Hydrothermal Method
Researchers synthesized TiO₂ nanorod thin films on FTO glass using a low‑temperature hydrothermal process, comparing growth with and without a spin‑coated TiO₂ seed layer. The seed layer dramatically increased nucleation sites, yielding uniformly distributed nanorods, whereas seed‑free samples produced larger,...
Stochastic Methods for Forecasting and Power System Mode Optimization with a High Share of Renewable Energy Sources: A Case Study...
The study introduces a hybrid forecasting framework that combines Long Short‑Term Memory (LSTM) neural networks with GARCH econometric models to predict solar generation in Tajikistan’s hydro‑centric power system. Tested on 2021‑2023 data, the two‑loop algorithm achieved a Mean Absolute Percentage...
Repeated Identification of Two Novel Poleroviruses in the Virome of French Grain Cereals
A five‑year metagenomic survey of French wheat and barley identified two novel poleroviruses, including barley virus H (BVH), which appears in 2.3 % of samples. BVH shares typical polerovirus genome organization but lacks ORF6 and ORF7, distinguishing it from known species. The...
Bronchial Branch Tracing with Cone-Beam CT Tool-in-Lesion Confirmation for Peripheral Pulmonary Nodules
A prospective single‑center study evaluated adding cone‑beam computed tomography (CBCT) to a bronchial branch tracing and radial EBUS workflow for peripheral pulmonary nodules. CBCT‑guided re‑navigation boosted navigational yield from 75% to 90% and raised diagnostic yield to 80%, compared with...
Comparison of Axillary Lymph Node Size in Breast Cancer and Non-Cancer Female Cadavers
A cadaveric study of 29 women—8 with prior breast cancer and 21 controls—found that axillary lymph nodes are significantly larger in the cancer group, with an average area increase of 56.7 mm² (p < 0.001). Nodes from all six anatomical chains showed the...
Long-Term Follow-Up Results of Topical Imiquimod for High-Grade Cervical Intraepithelial Neoplasia in Young Women: An Original Research
A retrospective single‑arm cohort studied topical imiquimod in nulliparous women under 35 with CIN 2/3 to avoid cervical excision. After eight weekly applications, 96% of lesions regressed to at least CIN 1 and 47% cleared high‑risk HPV. Long‑term follow‑up showed 81.6% complete...
Unexpected Red Blood Cell Antibodies in Transfusion Recipients: A 10-Year Retrospective Analysis of Prevalence, Specificity, and Clinical Significance
Researchers analyzed 44,830 Chinese transfusion recipients over ten years, finding that 0.46% harbored unexpected red blood cell antibodies and 0.39% were alloimmunized. Rh system antibodies dominated (58.3%), with anti‑E, anti‑M and anti‑D as the most frequent specificities, while anti‑K was...
Impact of Perioperative Multimodal Blood Management of Bone Tumors of Hip on Early Postoperative Functional Recovery: A Retrospective Cohort Study
A retrospective cohort of 38 hip bone tumor patients compared a peri‑operative multimodal blood‑management protocol—erythropoietin, iron supplements, and restrictive transfusion—to standard care. The multimodal group (n=14) entered surgery with lower hemoglobin and longer operative times but showed significantly higher FACIT‑Fatigue...
Anemia and Amino Acid Profiles Among Stunted Children in Rural Areas
A cross‑sectional study of 80 rural children examined anemia and amino‑acid status in 54 stunted versus 26 non‑stunted participants. Sixty‑three percent of stunted children were anemic, with 24.1% displaying iron‑deficiency anemia. Compared with peers, stunted children had lower albumin, total...
Accounting for Imperfect Displacement in Life Cycle Assessment for Refurbishing and Remanufacturing Operations
A new study proposes endogenizing the displacement rate (DR) in life‑cycle assessment for refurbishing and remanufacturing by modeling firm and customer decisions. The method calculates a market‑driven DR and compares it to a break‑even DR required for net environmental savings....
Evaluation of Machine Learning Models in the Prediction of Water Quality Index for Selected Water Sources in Uyo, Akwa Ibom...
A recent study in Uyo, Akwa Ibom State, Nigeria evaluated six machine‑learning algorithms to predict the groundwater quality index (GWQI) using thirteen physicochemical parameters. The LassoLarsCV model achieved a perfect R² of 1.0000 with zero RMSE and MAE, outperforming Ridge Regression,...
Outcomes of Treatment for Methicillin-Resistant Staphylococcus Aureus Ventilator-Associated Pneumonia
A retrospective study of 125 patients with MRSA‑associated ventilator‑associated pneumonia compared trimethoprim‑sulfamethoxazole (SMX‑TMP) to the standard vancomycin therapy. Mortality was 28% with SMX‑TMP versus 37% with vancomycin, a difference that was not statistically significant. Clinical cure rates at day 5 and...
Temperature Rise Characteristics of UHV AC Composite Insulators Under Type Fault Conditions
Researchers at the UHVAC Test Laboratory evaluated temperature rise in ultra‑high‑voltage AC composite insulators under several fault scenarios. Tests in a climate chamber showed that grading‑ring misalignment, reduced insertion depth, or complete absence significantly increase temperatures, with the greatest rise...
The Timing of Schedule-Induced Behavior
Researchers investigated schedule‑induced drinking (SID) in rats to see if the timing of excessive licking could be shifted away from the immediate post‑pellet interval. In Experiment 1, lick‑contingent delays failed to move SID, while a signaling cue actually amplified licking through...
Motivational Composition in Digitally Supported and Conventional Prevention Programs: A Three-Wave Study Based on Self-Determination Theory
A three‑wave quasi‑experimental study compared a digitally supported occupational prevention program with a conventional in‑person format among 163 German employees. While the digital cohort logged significantly higher attendance over 12 and 24 weeks, its Relative Autonomy Index—a measure of autonomous...
Frailty-Related and Hepatic Prognostic Markers in Acute Biliary Tract Infections: A Diagnosis-Stratified Retrospective Cohort Study
A retrospective cohort of 94 adults with acute biliary tract infections revealed markedly higher 30‑day mortality in acute cholangitis (30%) versus acute cholecystitis (4.1%). Patients with cholangitis also showed lower prognostic nutritional index, higher FIB‑4 scores, reduced albumin and hemoglobin,...
Peripheral Inflammatory Profiles in Acute Schizophrenia Relapse: Associations with 6- Month Antipsychotic Treatment Coverage
A retrospective analysis of 127 adults hospitalized for acute schizophrenia relapse examined how six‑month antipsychotic coverage—long‑acting injectable (LAI) monotherapy, regular oral monotherapy, or no treatment—relates to peripheral inflammatory markers. The study found that LAI treatment was consistently associated with lower...
Forecast-Driven Dynamic Physician Staffing in a Pediatric Emergency Department: A Prospective Quasi-Experimental Pilot Study
A prospective quasi‑experimental pilot at Hacettepe University Children’s Hospital tested forecast‑driven physician scheduling in its pediatric emergency department. Using the TiDE‑RIN deep‑learning demand model and linear programming, daily evening shift staffing was adjusted between three and six physicians. Compared with...
Correlates of Viral Load Suppression Among People Living with HIV on Antiretroviral Treatment in Mbujimayi, Democratic Republic of Congo: A...
A cross‑sectional study of 561 people living with HIV in Mbujimayi, Democratic Republic of Congo identified key behavioral determinants of viral load suppression. Strict antiretroviral therapy (ART) adherence increased suppression odds elevenfold, while having no casual sexual partners doubled the...
Association of Cervical Pessary Use with Preterm Birth in Singleton Pregnancies with a Short Cervix and Threatened Preterm Labor: A...
A retrospective cohort of 180 singleton pregnancies with threatened preterm labor and cervical length ≤25 mm compared cervical pessary use (2021‑2024) to historical controls (2017‑2020). Preterm birth before 37 weeks fell from 51.2 % to 20.9 % with pessary. Adjusted odds ratio 4.65...
Pulsed Intra-Arterial Infusion with Synchronously Controlled Blood Flow: A Novel Strategy for Optimizing Intra-Arterial Chemotherapy
Researchers introduced a pulsed intra‑arterial infusion technique with synchronized blood‑flow control (PBC‑IA) to improve chemotherapy delivery. In rabbit models, the method produced more than 20‑fold higher doxorubicin concentrations in the target gastrocnemius muscle compared with standard intravenous injection, while heart...
Gastropods (Mollusca) of the Priority Marine Region to Conserve Biodiversity No. 31 &Ldquo;Tlacoyunque”, Mexico, Associated with the Rocky Intertidal
Researchers surveyed the rocky intertidal of Mexico’s Marine Region 31, sampling nine 10 m² sites in 2015, 2016 and 2018. They identified 103 gastropod species, raising the regional total from 216 to 236, with inventory completeness between 78% and 89%. Five families...
A Comprehensive Method to Integrate Unbiased Fisheries Data in Spatially-Explicit Population Dynamics Models
The authors introduce a systematic method for preparing unbiased fisheries data for spatially‑explicit population dynamics models such as SEAPODYM. By grouping fishing operations into distinct fisheries with uniform catchability and selectivity, and preserving linear catch‑to‑biomass relationships at high‑resolution grid cells,...
Spring Greening Reduces Autumnal Runoff Across High Northern Latitudes
Spring greening across the high northern latitudes has increased leaf area and transpiration, leading to notable soil moisture depletion in summer. By combining satellite vegetation indices, runoff data from 297 watersheds, and LPJ‑GUESS model simulations, researchers found that this greening...
The Clinical Value of Genetic Testing in Lung Squamous Cell Carcinoma: A Retrospective Study
Researchers evaluated 1,515 lung squamous cell carcinoma patients, of whom 292 underwent genetic testing, uncovering a 19.2% driver mutation detection rate dominated by EGFR and MET alterations. Non‑smokers, females, and patients ≤65 years showed the highest mutation frequencies, especially EGFR...
Effect of a Multimodal Integrative Intervention on Quality of Recovery After Laparoscopic Colorectal Cancer Surgery: A Single-Center, Single-Blind, Pragmatic Randomized...
A single‑center, single‑blind randomized trial of 105 patients compared a multimodal integrative protocol—electroacupuncture, abdominal massage, breathing training and early ambulation—to standard postoperative care after laparoscopic colorectal cancer surgery. The primary Quality of Recovery‑15 (QoR‑15) scores showed no difference on days...
Gouty Tophi Within the Carpal Tunnel Leading to Severe Finger Flexion Contracture A Case Report and Short-Term Follow-Up
A 47‑year‑old man presented with a palmar wrist mass and severe ring‑finger flexion contracture caused by gouty tophi infiltrating the carpal tunnel. Imaging and intra‑operative findings confirmed extensive tophaceous involvement of the flexor tendons, leading to adhesion and nerve compression....
Integrated Analysis Identifies Disulfidptosis Related Tumor Antigens and Molecular Subtypes in Hepatocellular Carcinoma for mRNA Vaccine Development
Researchers developed a disulfidptosis‑based framework for hepatocellular carcinoma (HCC) that combines molecular subtyping, mRNA vaccine design, and prognostic modeling. Analysis of TCGA‑LIHC and GEO data identified 32 disulfidptosis‑related genes that separate HCC into two subtypes with distinct survival, immune infiltration,...
Overcoming the Semantic Bottleneck for Deterministic Structural Control in Text-to-Image Synthesis
The paper introduces Procedural Latent Prompt Injection (PLPI), a zero‑shot framework that embeds geometric priors directly into latent diffusion models, bypassing the need for extra training or language‑based conditioning. By modeling diffusion as a steerable stochastic differential equation, PLPI identifies...
Impact of Non-Intubated Spontaneous Breathing Versus Intubated General Anesthesia in Thoracoscopic Surgery on Postoperative Venous Thromboembolism
A retrospective study at Jinhua Central Hospital compared non‑intubated anesthesia with conventional endotracheal intubation in 55 lung‑cancer patients undergoing thoracoscopic surgery. The non‑intubated group showed earlier ambulation, more stable postoperative coagulation, and a reduced incidence of venous thromboembolism (VTE). No...
Persistent and Semivolatile Contaminants in Sediments of Nutrias Lagoon (Uruguay): Historical Trends and Potential Ecological Implications
Researchers examined a dated sediment core from Uruguay’s Nutrias Lagoon to trace historical levels of PCBs, PBDEs, mercury and PAHs. PCB‑52 was intermittently detected in late‑20th‑century layers, while PBDEs were absent and mercury remained stable at 65‑85 µg kg⁻¹, below international guidelines....
Statistical Investigation on the Failure of Misaligned Contaminated EHL Rolling Contacts Using Response Surface Methodology
Researchers used a Box‑Behnken experimental design and response surface methodology to model wear and surface roughness in misaligned, contaminated elastohydrodynamic lubrication (EHL) rolling contacts. Tests on steel disks varied misalignment angle, rotational velocity, load and contaminant concentration, revealing that rotational...
Projecting Environmental Improvements in Mineral Processing Pathways: The Case of Cathode Active Material Production
A new methodological framework evaluates future technological switches in mineral processing, focusing on cathode active material (CAM) production. By modeling seven switch categories, the study projects substantial environmental gains—up to 86% lower greenhouse‑gas impact, 99.8% reduction in human carcinogenic toxicity,...
Complementary Value of CEUS-Guided Hookwire Localization Combined with Methylene Blue Staining for Sentinel Lymph Node Detection, and the Predictive Role...
A single‑arm study of 76 patients evaluated contrast‑enhanced ultrasound (CEUS)‑guided hookwire localization combined with intra‑operative methylene blue staining for sentinel lymph node (SLN) detection. The dual‑modality approach identified SLNs in 73 patients, achieving a 96.05% overall detection rate, with each...
Reconstruction of Dialysis Access in an End-Stage Renal Disease Patient with Severe Peritonitis and Thoracic Deformity: A Case Report
A 39‑year‑old man with end‑stage renal disease, severe peritonitis, thoracic deformity, and extensive vascular calcification faced repeated dialysis access failures. After conventional fistula and graft attempts failed, clinicians placed a cuffed dialysis catheter via the left innominate vein using digital...
Exclosure Area Decreases the Spread of the Invasive Plant Senna Obtusifolia (L.) And Enhances Forage Value of Sahelian Rangelands
A four‑year grazing exclosure in Sahelian rangelands dramatically reduced the invasive Senna obtusifolia while boosting the abundance and diversity of native, high‑value forage species. Biomass, height and density of Senna fell sharply inside fenced plots, whereas companion species saw an...
Endothelial Erg Regulates Expression of Pulmonary Lymphatic Junctional and Inflammation Genes in Mouse Lungs Impacting Lymphatic Transport
Researchers created inducible, lymphatic‑endothelial‑specific Erg knockout mice to probe the transcription factor’s role in lung vasculature. Loss of ERG triggered an inflammatory gene signature and reduced expression of junctional proteins, compromising lymphatic endothelial cell (LEC) barrier integrity. Functional assays revealed...
Vitamin B12 and D Deficiency as Cofactors of COVID-19 Vaccine-Induced Chronic Neurological Adverse Reactions: Two Cases and a Hypothesis
Researchers reported two severe, chronic neurological reactions following COVID‑19 vaccination that were linked to underlying vitamin deficiencies. A 43‑year‑old man receiving the Pfizer shot recovered completely after vitamin B12 replacement, even when symptoms recurred after a booster. A 30‑year‑old woman...
Development of a Culturally Sensitive Breast Cancer Patient Education Toolkit in Rwanda: A Methodological Approach
Breast cancer cases in Rwanda are expected to rise from 1,131 in 2018 to roughly 2,420 by 2040, creating a critical need for patient education. OAZIS Health responded with the ICYIZERE Initiative, developing a culturally sensitive education toolkit through four...
Multi-Target Gene Therapy for Osteoarthritis: Dual-Axis Modeling and In Silico Validation
A computational study proposes a multi‑target gene therapy for osteoarthritis that combines anti‑inflammatory, anabolic, and catabolic‑blocking transgenes delivered via a dual‑vector AAV system. Network perturbation modeling shows the multi‑axis approach achieves an ECM Recovery Score of 76.2, markedly higher than...
A Dimension-Stone-Specific GIS-AHP Framework for Regional Quarry Suitability Screening in Under-Mapped Precambrian Basement: Application to Cameroon’s West Region, Central African...
Researchers introduced a GIS‑AHP framework tailored to dimension‑stone quarry screening in Cameroon’s West Region, a Precambrian basement area largely unmapped for mining potential. The model integrates nine geological, environmental, topographic and infrastructural criteria, producing a weighted‑overlay suitability map that classifies...
Tailoring Water-Resistant Hybrid Geopolymers with Triethoxyvinylsilane and Hexadecyl-Trimethoxy-Silane: A Comparative Study
Researchers enhanced metakaolin‑based geopolymers with two silane agents—triethoxyvinylsilane (TEVS) and hexadecyltrimethoxysilane (HTS)—to create water‑resistant composites. The untreated geopolymer showed a hydrophilic contact angle of 30°, while TEVS and HTS raised angles to 135° and 128°, respectively, confirming strong hydrophobic surfaces....
Gallbladder Volvulus and the Use of Indocyanine Green
A 65‑year‑old woman with a necrotic gallbladder volvulus underwent laparoscopic cholecystectomy aided by pre‑operative indocyanine green (ICG) fluorescence imaging. ICG enabled real‑time visualization of the common bile duct, necrotic cystic duct, and thrombosed cystic artery, facilitating safe detorsion and confirmation...
Image-Based Honeybee Colony Conditions Detection Using a Hybrid CNN–ANN Framework
A new hybrid deep‑learning system combines a dual‑branch CNN with a Multi‑Layer Feedback ANN to classify six honeybee health conditions from images. The model achieved 97.61% overall accuracy and a macro‑F1 score of 0.96, surpassing a traditional CNN‑Softmax baseline that...
Assessing Digital and AI-Readiness in Medical Education: A Delphi-Based Development of a Digital Health Competency Questionnaire
A Delphi-driven study created a 25‑item questionnaire to gauge medical students' digital health and AI competencies. Twelve experts, including ten educators and two senior students, refined an initial 26‑item draft over two consensus rounds, achieving a 96% agreement rate. The...
Association Between Leisure-Time Physical Activity and Health-Related Quality of Life of Corporate Bank Workers in Resource-Limited City
A cross‑sectional survey of 178 corporate bank workers in Ghana examined leisure‑time physical activity (LTPA) and health‑related quality of life (HRQoL). Most participants reported low to moderate LTPA levels while rating their HRQoL as generally high. Regression analysis revealed that...
Landslide Susceptibility Mapping Around Alkumru Dam (Siirt, Türkiye) Using Machine Learning and Ensemble Models
Researchers applied six machine‑learning algorithms and an ensemble model to map landslide susceptibility around Turkey’s Alkumru Dam reservoir. All models delivered strong predictive power, with AUC scores ranging from 0.877 to 0.959, and the Naive Bayes classifier achieved the highest...