ScienceDaily – Neuroscience - Latest News and Information
Technology Pulse
EMAIL DIGESTS
Daily
Every morning
Weekly
Tuesday recap
EMAIL DIGESTS
Daily
Every morning
Weekly
Tuesday recap
A study published in Gastroenterology demonstrates that stress during early life rewires gut‑brain pathways, increasing the risk of chronic digestive disorders. Mouse experiments showed sex‑specific motility changes and identified separate neural, hormonal, and serotonin mechanisms. Large human cohorts—over 40,000 Danish children and nearly 12,000 participants in the U.S. ABCD study—linked maternal depression and adverse childhood experiences to higher rates of IBS, constipation, colic and other gastrointestinal symptoms. Researchers argue that these insights could enable more precise, mechanism‑based treatments for gut‑brain disorders.
Scientists from VIB and KU Leuven have identified the mechanism by which lecanemab (Leqembi) clears amyloid plaques in Alzheimer’s disease. Their study shows that the antibody’s Fc fragment engages microglia, reprogramming them to phagocytose and degrade plaques. Removing the Fc...
A UCLA Health study links long‑term residential exposure to the pesticide chlorpyrifos with a more than 2.5‑fold increase in Parkinson's disease risk. Researchers analyzed 829 Parkinson's patients and 824 controls, estimating exposure through California pesticide records, and corroborated findings with...
Researchers at Houston Methodist identified the ALS‑linked protein TDP43 as a regulator of DNA mismatch repair genes. Dysregulated TDP43—whether under‑ or over‑expressed—triggers abnormal repair activity that destabilizes the genome. Analysis of large cancer datasets revealed that tumors with high TDP43...
Researchers have identified five biological pathways through which microplastics can damage the brain, potentially accelerating Alzheimer’s and Parkinson’s disease. The systematic review, led by University of Technology Sydney and Auburn University, highlights inflammation, oxidative stress, blood‑brain barrier disruption, mitochondrial impairment,...
