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GEN (Genetic Engineering & Biotechnology News)

GEN (Genetic Engineering & Biotechnology News)

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Genetic Engineering & Biotechnology News (GEN) offers global news and information on biotech and genetic engineering, including analysis, industry data, and technology updates.

Recent Posts

Beam Therapeutics Secures $500M Strategic Financing From Sixth Street
Deals•Feb 24, 2026

Beam Therapeutics Secures $500M Strategic Financing From Sixth Street

Beam Therapeutics announced a $500 million strategic financing agreement with Sixth Street to fund the potential launch of its sickle cell disease therapy and advance its BEAM‑304 program for phenylketonuria. The financing will support development of the gene‑editing platform and related clinical programs.

GEN (Genetic Engineering & Biotechnology News)
Boltz PBC Launches with $28M to Democratize AI Platforms for Drug Discovery
News•Jan 9, 2026

Boltz PBC Launches with $28M to Democratize AI Platforms for Drug Discovery

Boltz, a public benefit corporation founded by MIT CSAIL researchers, announced a $28 million seed round led by Amplify, a16z and Zetta Venture Partners. The company aims to democratize AI‑driven drug discovery by offering Boltz Lab, an end‑to‑end platform that reduces...

By GEN (Genetic Engineering & Biotechnology News)
Aragen Launches CHOMax Cell Line Development and Manufacturing Platform
News•Jan 9, 2026

Aragen Launches CHOMax Cell Line Development and Manufacturing Platform

Aragen Biologics introduced CHOMax, an integrated cell line development and early manufacturing platform for standard IgG monoclonal antibodies. Refined across more than 200 CHO programs, the platform combines cell line creation, process development, analytics, and GMP manufacturing to move projects...

By GEN (Genetic Engineering & Biotechnology News)
Proteomics at Scale: Current Approaches and Emerging Technologies
News•Jan 9, 2026

Proteomics at Scale: Current Approaches and Emerging Technologies

The new eBook "Proteomics at Scale" examines how emerging and traditional proteomics platforms balance protein coverage with analytical detail. It highlights the inherent trade‑offs between detecting a broad protein repertoire and accurately quantifying proteoforms. The publication introduces Nautilus™’ Iterative Mapping...

By GEN (Genetic Engineering & Biotechnology News)
Cellares and City of Hope Sign Deal to Automate Solid Tumor CAR T Cell Therapy Manufacturing
News•Jan 9, 2026

Cellares and City of Hope Sign Deal to Automate Solid Tumor CAR T Cell Therapy Manufacturing

Biotech firm Cellares and cancer research center City of Hope have entered a partnership to evaluate Cellares’ automated Cell Shuttle manufacturing platform and Cell Q quality‑control system for City of Hope’s investigational CARpool IL13RA2‑EGFR CAR‑T therapy targeting glioblastoma multiforme. The...

By GEN (Genetic Engineering & Biotechnology News)
Bone Marrow Immune Cell Map Boosts Survival, Relapse Prediction in Multiple Myeloma
News•Jan 9, 2026

Bone Marrow Immune Cell Map Boosts Survival, Relapse Prediction in Multiple Myeloma

Researchers created a single‑cell immune atlas of bone‑marrow cells from 337 newly diagnosed multiple myeloma patients, profiling nearly 1.4 million plasma and immune cells. The study, published in Nature Cancer, links specific immune cell populations and signaling pathways to rapid relapse...

By GEN (Genetic Engineering & Biotechnology News)
New Single‑Cell Testing Measures How Effectively Antibiotics Kill Bacteria
News•Jan 9, 2026

New Single‑Cell Testing Measures How Effectively Antibiotics Kill Bacteria

Researchers at the University of Basel introduced Antimicrobial Single‑Cell Testing (ASCT), a high‑throughput live‑cell imaging platform that quantifies antibiotic killing at single‑cell resolution. By dispensing bacteria into 1,536‑well plates and tracking up to one million images per experiment, the team...

By GEN (Genetic Engineering & Biotechnology News)
Stem Cell-Derived Neurons Navigate to Form Connections in the Injured Brain
News•Jan 8, 2026

Stem Cell-Derived Neurons Navigate to Form Connections in the Injured Brain

Researchers at Sanford Burnham Prebys and Duke‑NUS have demonstrated that human embryonic stem cell‑derived cortical neurons can be grafted directly into the lesion cavity of mice after ischemic stroke, survive, mature into NeuN‑positive neurons, and re‑establish long‑range connections. By tracing...

By GEN (Genetic Engineering & Biotechnology News)
Synaffix and Sidewinder Agree to Advance Next-Generation Bispecific ADC Development
News•Jan 8, 2026

Synaffix and Sidewinder Agree to Advance Next-Generation Bispecific ADC Development

Synaffix, a Lonza company, and Sidewinder Therapeutics have signed a multi‑target licensing agreement to co‑develop first‑in‑class bispecific antibody‑drug conjugates (ADCs) for solid‑tumor indications. The deal gives Sidewinder access to Synaffix’s GlycoConnect antibody‑conjugation, HydraSpace polar spacer, and toxSYN linker‑payload technologies, while...

By GEN (Genetic Engineering & Biotechnology News)
Cas12a3 CRISPR System Targets tRNA Without Destroying Host Cell
News•Jan 8, 2026

Cas12a3 CRISPR System Targets tRNA Without Destroying Host Cell

Researchers at Utah State University identified a novel CRISPR nuclease, Cas12a3, that selectively cleaves the 3′ CCA tails of transfer RNAs, halting protein synthesis without damaging host DNA. Unlike Cas9, which makes a single cut in DNA, Cas12a3 is activated...

By GEN (Genetic Engineering & Biotechnology News)
Novel Gene Therapy Approach Targets Pain Centers in the Brain
News•Jan 8, 2026

Novel Gene Therapy Approach Targets Pain Centers in the Brain

Researchers at the University of Pennsylvania have unveiled the first central‑nervous‑system‑targeted gene therapy designed to relieve chronic pain by modulating cortical opioid circuits. Using an AI‑driven mouse model, they identified a persistent affective pain signature that morphine reverses, then engineered...

By GEN (Genetic Engineering & Biotechnology News)
Advances in Extracellular Vesicle Separation and Isolation
News•Jan 7, 2026

Advances in Extracellular Vesicle Separation and Isolation

Finnish researchers reviewed the latest size‑, charge‑, and affinity‑based methods for extracellular vesicle (EV) isolation as exosome therapeutics move toward clinical use. They highlighted emerging size‑based techniques such as deterministic lateral displacement (DLD) with thermally‑oxidized tapered structures and viscoelastic microfluidic...

By GEN (Genetic Engineering & Biotechnology News)
Fungus with Hidden Talent Leads to Rethink on Making Classic Cancer Drug
News•Jan 7, 2026

Fungus with Hidden Talent Leads to Rethink on Making Classic Cancer Drug

Researchers have identified an endophytic fungus, *Colletotrichum siamense*, living inside the Madagascar periwinkle that can synthesize the chemotherapy drug vinblastine. The fungus produced the compound at a modest 138 µg per liter, matching the plant‑derived molecular signature. Laboratory tests confirmed that...

By GEN (Genetic Engineering & Biotechnology News)
Automated Lab of the Future May Herald Lower-Cost Therapies
News•Jan 7, 2026

Automated Lab of the Future May Herald Lower-Cost Therapies

German researchers at TU Berlin’s KIWI‑biolab have built a self‑driving laboratory that uses robotics, AI and bioinformatics to automate the development of new biomolecules. The system runs E. coli cultures in 10‑100 mL bioreactors, validates processes up to 100 L, and relies on...

By GEN (Genetic Engineering & Biotechnology News)
CCGT Sector Needs Purpose-Built Quality Management Systems
News•Jan 7, 2026

CCGT Sector Needs Purpose-Built Quality Management Systems

Researchers argue that traditional quality management systems, built for large‑scale protein drugs, are ill‑suited for cell and gene therapy (CGT) manufacturing. Manual, paper‑based processes have evolved into fragile eQMS platforms that struggle with the lean, modular nature of CGT production....

By GEN (Genetic Engineering & Biotechnology News)

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