De-Influencing Your Perimenopause Skincare: What Works & What to Quit with Dr. Mamina Turegano

Why It Matters

Clear, practical guidance helps middle-aged women prioritize evidence-based measures—proper sunscreen use and consistent basic routines—over transient influencer trends, directly reducing photoaging and skin cancer risk while better managing perimenopausal skin changes.

Summary

Dermatologist Dr. Mamina Turegano, on Dr. Stephanie’s podcast, lays out a simplified perimenopausal skincare playbook: splash with water and apply broad-spectrum sunscreen each morning, and wash makeup off and moisturize each night. She stresses correct sunscreen dosing (about 1/4–1/2 teaspoon for the face, more for neck/ears/hands; about an ounce for the body), reapplication outdoors, and prefers creams over sprays for reliable coverage. Turegano warns against overhyped trends and unnecessary early use of actives (e.g., teens using retinol), and addresses common perimenopausal concerns including dryness, hyperpigmentation, melasma and inflammatory conditions. The episode also touches on digestive enzyme supplementation for age-related bloating and nutrient absorption.

Original Description

If you have been getting your skincare advice from 60-second reels and 18-year-old influencers, this episode is your reset.

Dr. Mamina Turegano is not your average dermatologist. Triple board-certified in dermatology, internal medicine, and dermatopathology, she has spent 16 years in practice connecting what shows up on the surface to what is happening inside the body. Today, she is here to de-influence your skincare routine and give you the science-backed truth about what perimenopausal skin actually needs.

This is the episode to send to every Betty who has ever felt overwhelmed in the skincare aisle. The answer is simpler -- and more internal -- than the industry wants you to believe.

Episode Overview:

0:00 Intro/Teaser

5:03 How to actually wear sunscreen

8:05 What estrogen loss does to skin in perimenopause

16:40 Estrogen cream on the face

20:55 Melasma and hyperpigmentation

30:00 Retinol vs tretinoin, how to onboard, and the skin-thinning myth busted

49:00 Eczema, psoriasis, gut health, fiber, and stress-triggered skin conditions in midlife

1:09:33 Collagen peptides, niacinamide, polypodium leucotomos, urolithin A

1:25:32 Home device ratings: red light therapy, microneedling, microcurrent

1:36:13 Why strength training and glutes improve your skin

1:41:08 After-party with Dr. Stephanie

Resources mentioned: https://drstephanieestima.com/podcasts/ep470

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**P.S. When you're ready, here are two ways Dr. Stephanie can help you:

Subscribe: The Mini Pause — My weekly newsletter packed with the most actionable, evidence-based tools for women 40+ to thrive in midlife. https://drstephanieestima.com/newsletter

Build Muscle: LIFT — My progressive strength training program designed for women in midlife. Form-focused, joint-friendly, and built for real results. https://drstephanie.ca/lift