
Designing With Chaos: The New Paradigm in Nanoelectronics
The lecture reframes electronic noise from a nuisance to a design asset in nanoelectronics, arguing that stochastic fluctuations become indispensable as device dimensions shrink to a few hundred atoms. Traditional engineering seeks to suppress noise, but at the nanoscale the signal‑to‑noise ratio drops dramatically, making thermal jitter comparable to the signal itself. Key mechanisms are explored: stochastic resonance, where an optimal noise level lifts sub‑threshold signals above detection thresholds; Brownian ratchets that harvest asymmetric potentials and thermal kicks to generate directed transport, exemplified by molecular motors like kinesin; and noise‑enhanced stability, which uses thermal activation to escape local minima and improve magnetic memory reliability via heat‑assisted recording. The speaker also discusses noise‑induced phase transitions and the role of multiplicative noise in stabilizing genetic toggle switches. Illustrative examples include crayfish mechanoreceptors that exploit ambient water noise, single‑electron transistors that operate near the Coulomb‑blockade threshold using charge fluctuations, and stochastic‑computing architectures that encode probabilities in random bit streams. Fundamental relations such as the fluctuation‑dissipation theorem and Crooks’ theorem are invoked to show how noise quantifies dissipation and can even serve as a measurement tool. The takeaway for engineers is a set of design principles: align device energy barriers with ~10‑50 kBT thermal energy, embed spatial or temporal asymmetry to bias stochastic dynamics, and supply non‑equilibrium energy (chemical, electrical, or thermal) to sustain functionality. These concepts promise ultra‑low‑power neuromorphic and probabilistic processors, but practical hurdles—precise noise control, temperature management, and device variability—must be overcome to translate the paradigm into commercial technology.

From Molecules to Metaphors: When Science Inspires Fiction with Julia Kalow
The Nanocape episode spotlights Dr. Julia Kalow, a Northwestern chemist who bridges nanotechnology research with a background in creative writing. Kalow explains how storytelling techniques sharpen her scientific thinking, from drafting grant proposals to framing experimental questions, and how she...