Update on Brad Stanfield's Rapamycin Clinical Study in NZ

Summary

LukeMV: I hesitate to take it again since none of us really know what the best way to take it is. There seems to be a relatively small margin of error with the dosing. If we mess it up, it can be a net negative. I don’t think that’s true. The mouse studies show greater benefits with higher doses and we haven’t even found the dose that is too high for mice. Since they take a lot relative to humans I don’t think that’s suggestive of small margin of error. I don’t think rapamycin has a narrow therapeutic range, and for people that are concerned about getting in the range of taking too much, just stay on the safe side and take a very moderate dose. In general, the lower the dose you take the lower the chances that any benefits will be small enough to not reach significance. However the lower the dose, the higher the chances of the benefit/risk ratio being higher.