Leukemia Drug HHT Delays Aging, Extends Mouse Lifespan
Homoharringtonine exhibits senotherapeutic activity that mitigates diet- and age-associated obesity and insulin resistance and extends lifespan in mice [an FDA-approved anti-leukemic drug; authors found that "HHT treatment delays aging and extends the lifespan in progeroid and aged mice"] https://t.co/LEegM8XUtR
Longevity Expert Dr. Charlop Joins FOX Business Roundtable
Dr. Gregory Charlop here. I’m excited to announce I’m a featured longevity expert on FOX Business. I’ll be appearing on the Barron’s Roundtable to discuss common-sense health solutions for executives and family offices.
First FDA‑approved Longevity Drug Targets Dogs First
NEW Exclusive Interview: This miracle pill could make dogs live longer, with Celine Halioua, Founder & CEO of Loyal @celinehalioua is building the first drug ever FDA-approved for lifespan extension itself — starting with dogs. We sat down on Onward to...
Centenarians Retain Youthful Immune Profile, Hinting at Longevity
Centenarians show immune function found in younger individuals. Their immune system show reduced inflammatory signaling, enhanced autophagy, and controlled cellular senescence. They have low or no autoimmune disease, robust immunity against cancer and a distinct immune cell profile. Together, these...
Plasma Spermidine Mirrors Diet Slightly; Muscle Levels Regulated
"Spermidine, a polyamine abundant in plant-based and fermented foods, has been associated with reduced cardiovascular and all-cause mortality. However, whether dietary spermidine intake is reflected in circulating and skeletal muscle concentrations remains unclear, and tissue data are scarce... These findings...
2026‑2035 Longevity Metatr
I've spent decades studying exponential tech, and this longevity report is one of the most important I've done. My 2026–2035 Longevity Metatrends Report covers the breakthroughs that will redefine healthspan, performance, and the meaning of aging. Read it here: https://t.co/mLVBlpmmCg
Unproven “Mitochondrial Activator” Risks Echo Deadly DNP
Some functional medicine doctors are prescribing a drug with essentially zero human safety data. The drug is called SLU-PP-332. It’s being marketed in some circles as a “mitochondrial activator” or exercise mimetic. Here’s the problem: as far as I can tell, there...
Longevity Biotech Matures: Precise Indication‑Focused Drug Development
The longevity biotechnology field is coming of age in the best possible way. A recent analysis captures how the sector has learned to speak pharma’s language fluently—moving from broad claims about “slowing aging” to precise, indication-focused drug development with conventional endpoints,...
Methylene Blue: From Dye to Mitochondrial Therapeutic Breakthrough
As a medical school professor, I have watched methylene blue go from a 19th-century dye to a serious mitochondrial story. A new paper adds a striking chapter. (1/4)
Ovarian Age Clocks Predict Menopause Years Early
Know Exactly When You Stop Ovulating As a medical school professor, I keep coming back to one number women have never had access to: when your ovaries will actually stop. A new generation of "ovarian age clocks" — blood-based and follicular markers...
Genes Only Explain Up to Half of Lifespan
5 Longevity Myths the Latest Science Has Just Debunked As a medical school professor, I just published a piece walking through 5 longevity beliefs that the latest peer-reviewed evidence has flipped. 1. "Your genes determine how long you live." A 1996 twin...
Meet Kate Tolo: First Ultra‑Measured Woman for Free Health Data
We now have a female Bryan Johnson. It’s Kate Tolo. She will become the most measured female in history. +$2 million of spend per year + Developing a female-specific protocol + Sharing everything for free To start, she will spend 3 months mapping her baseline....
Essential Anti‑Aging Habits Most People Overlook
The “anti-aging stack” most people miss: - getting lean (3,500 mg of dietary potassium a day
Exercise Remodels Mitochondrial Quality Control to Slow Aging
The role of exercise-mediated mitochondrial quality control remodeling in aging https://t.co/EYmKmjpRDA Mechanisms by which Different Exercise Modes Regulate MQC to Delay Aging. 👇👨⚕️ https://t.co/Dz5bQtrExK
Blood Reveals and Controls Aging Mechanisms
Blood as the mirror and modulator of aging: mechanistic insights and rejuvenation strategies https://t.co/WayE8XIBWp https://t.co/dZt8wHQ2yp