Longevity Social Media and Updates
Longevity Social Media and Updates
Longevity Pulse
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Tuesday recap
EMAIL DIGESTS
Daily
Every morning
Weekly
Tuesday recap
As a medical school professor, I teach that autophagy -- the body's cellular recycling system -- is one of the most powerful defenses against aging and disease. Now the first-ever human clinical trial proves a fasting mimicking diet activates it. Cedars-Sinai and UT Health San Antonio tested a 5-day FMD in 30 adults: -> Autophagy flux sig... https://fastforhealth.co/ https://pubmed.ncbi.nlm.nih.gov/41372565/ Autophagy #FastingMimickingDiet #MetabolicHealth #Longevity #HealthLongevitySecrets
As a medical school professor, I teach students that Alzheimer's has many risk factors. But this one is invisible -- and almost nobody talks about it. A massive study of 27.8 million Medicare beneficiaries just found that fine particle air pollution...
enjoying this piece on record life expectancy increasing over time - the *insane* linear regression in 1840 - 2010 period just tracking record life expectancy over time (I think trend not consistent since, partic w COVID) - how funny it is that...
A mutation in the IVNS1ABP gene causes a new disease combining premature aging and severe neurological decline by disrupting cell scaffolding, leading to DNA damage and “zombie-like” senescent cells. https://t.co/xtDrjy72h4
🤣 That’s why we make sure the reprogramming technologies we develop can’t take cells back in epigenetic age more than ~75%
Facial aging is not a surface-level process. It reflects progressive changes in bone structure, fat compartments, collagen architecture, UV exposure, and hormonal signaling over time. The important point is that many of these pathways are modifiable. Daily photoprotection, resistance training, adequate...
Longevity 2.0: Your next doctor won't prescribe pills—they'll prescribe gene therapies, epigenetic reprogramming, and personalized longevity protocols. Medicine is shifting from "treat symptoms" to "reverse aging at the cellular level."
Dehydration can shrink your brain by over 0.5%, and may be a reason you get a headache. Hydrate to maintain light yellow urine. Also hydrate before an MRI, as dehydration-related small decreases in brain volume can confound MRI-based assessment...
This study on visceral fat loss blew my mind... It found that sustained visceral fat reduction over years was linked to preserved brain volume and cognitive function in middle age. They tracked people for up to 16 years, and those who lost...
Astaxanthin is a major antioxidant that's 100x more potent than vitamin E and vitamin C - protects skin against UV damage - lowers inflammation and neuroinflammation - lowers lipids and blood pressure - protects against oxidation of fats - protects the eyes - senolytic properties - lowers...
One reason I dislike saying healthspan or lifespan & prefer aging as label for the field over longevity. Aging puts focus on its terrible consequences/pathology. It makes the field defensive like medicine not greedy as some see wanting more life...
As a medical school professor, I've seen textbooks call it "metabolically healthy obesity." A new study proves that label is dangerously misleading. Karolinska Institute tracked 7,275 children with obesity until age 30. The results in JAMA Pediatrics are staggering: -> 9% of "metabolically...
When 'Normal Labs' Are Unhealthy We sit down with Dr Sandeep Palakodeti —an Ivy League–trained internist who left elite institutions—to unpack why so much of healthcare reacts to disease instead of building durable health, and how treating your body like your...
As a medical school professor, I've recommended metformin to countless patients. But a new double-blind trial just revealed something alarming. Metformin BLUNTED the insulin-sensitizing benefits of exercise in adults at risk for metabolic syndrome. The findings from a 16-week RCT: -> Exercise +...
Lp(a) is the new Voldemort of cardiology—a genetically determined risk factor that can raise your risk of heart disease by >200%. And while elevated Lp(a) is largely written into your DNA, there’s good news: You may be able to neutralize its...
Paragon launched its 7th company today -- Korsana Biosciences, merging into the $CYCN public shell. New ticker will be $KRSA. Lead drug candidate is a shuttled anti-amyloid beta antibody for Alzheimer's disease in early studies. https://t.co/RcJ8adMakm
The longevity factor spermidine is part of a highly heritable complex erythrocyte phenotype associated with longevity https://t.co/rHT8XoWHFz
social disconnection is not just painful emotionally, it puts the body under biological stress. It is linked to higher inflammation, worse cardiovascular health, and a higher risk of early death, while stronger social relationships are consistently associated with better survival....
Sleep loss can causally drive heart disease. 1/2) Here's how it works: Sleep loss causes release of a brain hormone (hypocretin) --> goes to bone marrow to simulate the production of inflammatory cells --> these go to arteries and drive atherosclerosis But...
