Nonlinear and Sex-Specific Associations of Maternal Vitamin D in Early- and Mid-Pregnancy with Childhood Growth Trajectories From Birth to 6 Years...
A prospective cohort of 1,100 Chinese mother‑child pairs found nonlinear, sex‑specific associations between maternal vitamin D levels in early and mid‑pregnancy and offspring growth trajectories from birth to age six. Low early‑pregnancy vitamin D increased odds of rising height‑for‑age and BMI‑for‑age Z‑scores, while low mid‑pregnancy vitamin D raised odds of increasing weight‑for‑age and height‑for‑age Z‑scores. Conversely, high early‑pregnancy vitamin D was linked to higher BMI trajectories, especially in boys. The lowest risk of adverse trajectories occurred when maternal 25‑hydroxyvitamin D was between roughly 30‑75 nmol/L, suggesting both deficiency and excess are detrimental.
Metabolic Features in Plasma and Urine of Obese Children and Their Association with MAFLD Risk
Researchers analyzed plasma and urine from 160 obese Chinese children aged 7‑14, identifying four metabolites linked to metabolic dysfunction‑associated fatty liver disease (MAFLD). Elevated plasma alanine and proline were associated with higher MAFLD risk, while higher urinary hippuric acid and...
The Relationship Between Nutrition Status Indicators and Vitamin D Deficiency in Patients with Type 2 Diabetes Mellitus
A cross‑sectional analysis of 285 hospitalized type 2 diabetes patients in Hebei found that 62% were vitamin D deficient (25‑hydroxyvitamin D < 20 ng/mL). Lower total protein levels were significantly linked to higher odds of deficiency, with an adjusted odds ratio of 0.933 per gram‑per‑liter increase....
Maternal Serum Ferritin Across Gestation and Risk of Small-for-Gestational-Age: A Longitudinal Cohort Study
A longitudinal cohort of 17,451 Chinese pregnancies found that elevated maternal serum ferritin in the third trimester is linked to a higher incidence of small‑for‑gestational‑age (SGA) infants. Women with ferritin ≥18.1 ng/mL at 29‑31 weeks had a 42% greater adjusted odds of...
The Dish-I-Wish Open Dataset on Food Preferences and Parental Influence
The researchers have released the Dish‑I‑Wish open dataset, capturing food‑selection behavior of 203 Russian children aged 4‑14. Using a gamified web app, participants chose meals for themselves and indicated what they believed their parents would serve, providing both autonomous and...
Socioeconomic Stratification in the Association Between Tea Consumption and Skeletal Muscle Mass Among Oilfield Workers
A cross‑sectional study of 2,574 Chinese oilfield workers found that habitual tea consumption is linked to higher appendicular skeletal muscle mass (ASM). In fully adjusted models, low‑level tea intake raised the skeletal muscle index by 0.105 units and high‑level intake...
Vitamin D Status and Site-Specific Fracture Pattern Associations in Older Adults with Fragility Fractures: A Cross-Sectional Analysis of 2543 Patients
Researchers analyzed 2,543 patients aged 60 and older hospitalized for fragility fractures in China. They found that 35.9% were vitamin D deficient and 44.2% insufficient, with deficiency linked to older age, female sex, winter admission, and prior cerebral infarction. Serum 25(OH)D...
Hepatoprotective Potential of JHB, a Functional Beverage, in a Mouse Model of Acute Alcohol-Induced Liver Injury
The Frontiers in Nutrition study shows that Jiuxiangfeng Houwuyou Beverage (JHB), a flavonoid‑rich plant‑based drink, markedly protects mice from acute alcohol‑induced liver injury. Pretreatment lowered serum ALT and AST, reduced oxidative stress markers, suppressed inflammatory cytokines, and boosted ADH and...
Effects of Macro- and Micronutrient Intake on Bone Mineral Density, Osteoporotic Fracture Risk, Inflammation, and Functional Rehabilitation Outcomes in Orthopedic...
A systematic review of 95 studies examined macro‑ and micronutrient interventions in orthopedic patients, finding moderate improvements in bone mineral density (SMD 0.47) and large reductions in bone turnover markers (SMD ‑0.69) and inflammatory markers (SMD ‑1.34). Post‑operative recovery outcomes showed a strong...
Health Characteristics of Recreationally Active Female Cannabidiol Users: A Real-World Cross-Sectional Study
A cross‑sectional study of 149 recreationally active women aged 18‑40 examined real‑world cannabidiol (CBD) use. Current users (n=78) reported significantly lower physical activity, shorter sleep duration and poorer quality‑of‑life scores than non‑users, while dietary quality was modestly higher and tobacco...
Risk of Gastrointestinal Intolerance and Complications Associated with Homemade versus Commercial Enteral Nutrition in Critically Ill Patients: A Single-Center Retrospective...
A retrospective cohort of 605 ICU patients compared commercial enteral nutrition (CEN) with hospital‑compounded individualized commercial formulation (ICF). ICF patients experienced markedly lower diarrhea (13.6% vs 41.5%), fewer feeding interruptions, higher mean daily calories (951 kcal vs 893 kcal), and dramatically reduced...
An Evidence Mapping Study Based on Systematic Reviews of Traditional Chinese Medicine for Hyperuricemia
An umbrella review of eleven systematic reviews evaluated Traditional Chinese Medicine (TCM) and integrated TCM‑Western (ITCW) therapies for hyperuricemia. The pooled data suggest that both TCM monotherapy and ITCW reduce serum uric acid levels and improve total effective rates compared...
Novel Prediction Equations for Appendicular Skeletal Muscle Mass in Hemodialysis Patients: Referenced Against Bioelectrical Impedance Analysis
A cross‑sectional study of 111 maintenance hemodialysis patients found that three widely used anthropometric equations for estimating appendicular skeletal muscle mass (ASM) performed poorly against multi‑frequency bioelectrical impedance analysis (BIA). Researchers created two dialysis‑specific models, an advanced height‑weight (HW) equation...
Gastrointestinal Tolerance to a Standardized Milk-Based Hydration Strategy Is Similar Across Exercise Modalities
A randomized crossover trial compared gastrointestinal (GI) tolerance of low‑fat, lactose‑free A2 milk during treadmill running and stationary cycling, matching intensity, duration, and fluid volume. Overall GI symptom burden was statistically equivalent between the two modalities, despite cycling showing higher...
Male Sex and Iron Deficiency Risk at 6 Months: The Mediating Role of Rapid Weight Gain
A retrospective cohort of 355 term infants in Chengdu found that male infants had a significantly higher prevalence of iron deficiency (ID) at six months (27.9% vs 15.8% in females). Rapid weight gain during the first six months was independently...