Alnylam Unites With Tenaya in Potential $1B+ Pact To Find New Genetic Heart Disease Targets
Alnylam Pharmaceuticals has signed a deal with Tenaya Therapeutics, providing $10 million upfront and the potential for up to $1.13 billion in milestones to discover up to 15 new genetic targets for heart disease. Tenaya will apply its modality‑agnostic platform to validate these targets, after which Alnylam will assume development and commercialization using its RNA‑interference expertise. The agreement expands Alnylam’s cardiovascular portfolio beyond its approved ATTR‑CM therapy, Amvuttra, and adds a pipeline of disease‑modifying candidates. The partnership reflects a broader resurgence of biotech investment in genetic cardiovascular solutions.
BJ Earnings: BJ’s Wholesale Club Q4 2025 Profit Increases, Beats Estimates
BJ Wholesale Club reported adjusted earnings of $0.96 per share for Q4 2025, up from $0.93 a year earlier and ahead of analyst expectations. Net income rose to $125.9 million, while membership fee revenue climbed 10.9% YoY to $129.8 million. Net sales increased 5.5%...
Former PlayStation and Xbox Hiring Lead Launches Rocket Game Talent
Former Sony PlayStation and Xbox Game Studios talent leader Fiona Cherbak has founded Rocket Game Talent, a boutique fractional talent firm. The company targets indie developers, startups, and growing studios that lack the hiring infrastructure of major publishers. It will...
Middle East War Jitters See Boxship Rates Jump 20% on Asia-Europe
Container freight rates on the Asia‑to‑North‑Europe lane have jumped sharply after the outbreak of war in the Middle East. Spot rates are up roughly 20%, while forward contracts for the next weeks and months are priced 20‑30% higher. The surge...
Original Content on Social: Harder to Find, but More Important for Brands to Nail
A new Sprout Social report shows just 56% of social users think brands deliver truly original content. Meanwhile, about one‑third find trend‑jacking embarrassing and only 27% consider it effective if executed within 48 hours. Marketers are prioritizing AI‑generated assets, yet...
Three Surprising Insights From The Forrester Wave™: Merchant Payment Providers, Q1 2026
The latest Forrester Wave™ for Merchant Payment Providers reveals that uptime is no longer a competitive edge; instead, strategic factors dominate. Five of nine evaluated vendors have recently undergone leadership or ownership changes, prompting potential shifts in pricing, packaging, and...
12 Best Rank Tracker Tools I've Tested
Rank tracker tools monitor keyword positions across search engines, offering daily updates, SERP‑feature insights, and competitor analysis. The article reviews twelve leading solutions—from Surfer and Ahrefs to Nightwatch and AccuRanker—highlighting each platform’s unique capabilities such as local‑level tracking, AI‑driven overviews,...
Inside a Startup Building Tools for AI Agents
Circuit & Chisel, a New York startup founded by former Stripe crypto executives, raised $19.2 million to launch ATXP, an agent transaction protocol that enables AI agents to navigate and execute payments autonomously. The company’s backers include Stripe, Polygon Labs, and Samsung Next, signaling strong...
Building the ROI Case for AP Automation – Webinar Highlights
Controllers Council hosted a webinar, sponsored by AvidXchange, on building a data‑driven ROI case for accounts‑payable (AP) automation. Speakers highlighted the hidden costs of paper‑based AP, from lost invoices to error‑driven delays, and outlined six ROI categories such as labor...
Investcorp Picks up More than $1.25bn to Close Second GP Staking Fund
Investcorp has closed its second general‑partner (GP) staking fund, raising more than $1.25 billion from a diversified investor base. The vehicle will acquire minority equity positions in private‑equity and hedge‑fund managers, offering them liquidity and strategic support. Compared with the firm’s...
SEC Announces Roundtable on Options Market Structure Reform
The U.S. Securities and Exchange Commission will hold a public roundtable on April 16, 2026, to examine the structure of listed options markets. The discussion will address competition in a quote‑driven environment, the retail investor surge, and the overall customer...
SONAR Launches New Geopolitical Alert and Fuel Dashboards to Help Supply Chains Navigate Iran Conflict Volatility
SONAR introduced two platform enhancements—a Geopolitical Alert on its Executive Dashboard and a Fuel Dashboard within Truckload Insights—to give logistics professionals real‑time visibility into Iran‑related conflict risks and energy price swings. The Geopolitical Alert supplies immediate context, curated resources, and...
7shifts Accelerates Growth and Industry Leadership with Major Customer Expansions, Product Innovation, and Workplace Recognition
7shifts announced a wave of enterprise rollouts, adding marquee franchise partners such as IHOP and HCI Hospitality while expanding its payroll and compliance suite. The company introduced Multi‑EIN payroll, ADP Workforce Now integration, and the Clair Earned Wage Access feature...
Codenotary Trust Delivers Autonomous AI Security for Linux and Kubernetes
Codenotary unveiled Codenotary Trust, a SaaS platform that leverages artificial intelligence to detect, prioritize, and autonomously remediate security, configuration, and performance issues across Linux, containers, VMs, and applications. The solution is built for junior and mid‑level administrators, addressing the talent gap...
US, China and Allies Pressure Ghana over Proposed Gold Royalty Hike
Ghana plans to replace its fixed 5% gold royalty with a sliding scale of 5‑12% tied to bullion prices, aiming to capture more revenue as gold hits record highs. A coordinated diplomatic push from the US, China, the UK, Canada,...
Revolut Names US CEO as It Seeks New Banking Licence
Revolut has appointed former Raisin chief executive Cetin Duransoy as its U.S. CEO, coinciding with the fintech’s application for a national bank charter from the OCC and FDIC. The company aims to operate as Revolut Bank US, giving it direct...
Sensing Your Way to a Smoother Supply Chain
Supply chain management is being transformed by rapid advances in sensor technology, with the logistics sensor market projected to grow from $10.5 billion in 2024 to $25.8 billion by 2033. Ambient IoT, exemplified by Wiliot’s battery‑free Pixel tags, is giving Walmart item‑level...
Validio Closes $30M Series A to Address Enterprise Data Quality Challenges
Validio secured a $30 million Series A round led by Plural, bringing total funding to $47 million, to scale its AI‑focused data‑quality platform. The solution automates monitoring, anomaly detection, and lineage cataloguing, replacing thousands of manual checks for enterprises in regulated sectors. Customers...
Affordability Posts Mild Gains in Second Half of 2025 but Crisis Continues
The NAHB/Wells Fargo Cost of Housing Index shows a modest uptick in affordability in Q4 2025, with a median‑priced new home requiring 34 % of a typical family’s income and an existing home 34 % as well. Low‑income households still face severe strain, needing...
AMV BBDO's Nadja Lossgott and Nick Hulley Prepare to Exit
AMV BBDO announced that longtime partners Nadja Lossgott and Nick Hulley will leave the agency at the end of April. Both have been instrumental in driving the firm’s integrated campaigns and client wins over the past decade. Their exit comes...
Databricks Built a RAG Agent It Says Can Handle Every Kind of Enterprise Search
Databricks unveiled KARL, a reinforcement‑learning‑driven RAG agent that tackles six distinct enterprise search behaviors in a single model. The system matches Claude Opus 4.6 on the proprietary KARLBench benchmark while delivering 33% lower cost per query and 47% reduced latency. KARL...
No Missiles, No Drones: What Happens When Rare Earths Stop Flowing?
China controls roughly 90‑95% of global rare‑earth processing, creating a strategic vulnerability for U.S. defense and high‑tech sectors. In response, REalloys (NASDAQ: ALOY) is building North America’s first fully integrated, China‑free heavy rare‑earth supply chain, with a production facility in...
Revolut Business Introduces Titan in the UK, Offering 10GB Global Data, Other Incentives
Revolut Business has launched Titan, a premium Visa‑linked corporate card for UK companies, bundling 10 GB of global mobile data, unlimited airport lounge access, and a 1:1 RevPoints rewards scheme. The card integrates real‑time expense tracking, receipt matching, and instant reconciliation...
Nigeria’s Loan Apps Are Pulling Back From the Small Loans that Built Them
Nigeria’s digital lending boom built on instant nano‑loans of ₦5‑10,000 is receding. Regulatory crackdowns on intrusive phone‑data and new FCCPC fines have stripped lenders of cheap risk tools, while credit‑bureau fees and high recovery costs make tiny loans unprofitable. Lenders...
Push Security Adds Malicious Browser Extension Detection to Block Threats in Employee Browsers
Push Security has introduced a malicious browser‑extension detection and blocking feature within its browser‑based security platform. The capability leverages a continuously updated intelligence database to automatically block known‑bad extensions and provide real‑time visibility into all extensions across employee browsers. Administrators...
Saba Capital Launches UK Investment Trust ETF: UKIT
Saba Capital Management has launched the UKIT, an actively managed UCITS ETF that invests in UK‑domiciled investment trusts trading at sizable discounts to net asset value. The fund targets a diversified portfolio of 40‑60 trusts across equities, bonds, real estate...
Assessing North Korea’s New Economic Five-Year Plan
North Korea’s Ninth Party Congress unveiled a five‑year plan focused on stabilization, consolidation and modest qualitative development rather than rapid growth. The agenda places the power sector at the core, linking factory construction, hospital building and agricultural mechanisation to reliable...
Italy Plans to Send Help to Gulf States After Iranian Strikes, Meloni Says
Italy announced it will send air‑defence assistance to Gulf states following Iranian strikes, aligning with the UK, France and Germany. Prime Minister Giorgia Meloni emphasized the move protects thousands of Italian expatriates and roughly 2,000 troops stationed in the region while...
SaaSpocalypse: What’s Next for Europe’s SaaS Scaleups and Investors?
A new Claude AI tool for the legal sector triggered a sell‑off in major SaaS stocks, reviving fears that AI‑native startups could displace traditional software giants. The Sifted podcast examines whether Europe’s VC‑backed SaaS scale‑ups can survive this “SaaSpocalypse” and...
Oh Jibbitz! LoveShackFancy Puts A Whimsical Spin On Crocs
LoveShackFancy has teamed with Crocs for a limited‑edition spring collection that debuts on March 5. The line includes classic clogs, platform clogs and ballet‑style flats, all drenched in the brand’s pastel floral prints, bows, gold accents and interchangeable Jibbitz charms. Prices...
Middle East War Could Trigger Currency Shock Across Africa - Fitch
Fitch Solutions warns that a broader US‑Iran conflict could trigger a sharp currency shock across sub‑Saharan Africa. In a prolonged escalation, Brent crude is projected to trade between $110 and $130 per barrel, raising energy costs and disrupting shipping routes....
The Verified Source Pack Agents Trust First via @Sejournal, @DuaneForrester
The article introduces the Verified Source Pack (VSP) as a new infrastructure layer that delivers machine‑readable, authoritative truth for AI agents. It outlines four core components—content, structure, provenance, and discoverability—and explains how VSPs complement existing pages and schema. The piece...
Exclusive: Founded By 2 Brothers In Their 20s, YC-Backed Denki Raises $4.1M To Automate Financial Audits
Denki, a YC‑backed AI startup founded by two brothers, raised $4.1 million to automate financial audits for public companies. The funding, led by Base10 Partners and Shine Capital, comes as fintech AI investment surged 27 % in 2025. Denki’s platform replaces manual,...
Looking to Grow Like a Top 100 Firm? Try CAS
Client accounting services (CAS) emerged as the fastest‑growing niche among the 2026 Top 100 accounting firms, with 85% of the 88 respondents reporting revenue gains—up five points from the prior year. The service line now spans bookkeeping, cash‑flow forecasting, budgeting, and...
Blaze Pizza Partners with Marvel Television's 'Daredevil: Born Again Season 2'
Blaze Pizza has launched a limited‑edition Sweet Heat pizza in partnership with Marvel Television’s Daredevil: Born Again Season 2, debuting on Disney+ March 24. The pizza, featuring spicy red sauce, double pepperoni, roasted red peppers, mozzarella and Mike’s Hot Honey, hit U.S....
Waynova Group Unveils Unified Technology Platform
Waynova Group has combined four specialized rail‑technology firms—ZEDAS, Railroad Software, Raspberry Software and Automated Rail—into a single international platform. The unified solution delivers software and hardware for asset management, maintenance, inspection, yard operations, revenue protection and field devices across North...
Guideline Launches Media Plan Management MCP Server, Enabling Agentic AI Workflows Across Media Planning & Buying
Guideline launched its Media Plan Management MCP Server, allowing agencies and advertisers to link any MCP‑compatible AI agent—such as Claude or ChatGPT—to its media planning platform. Built on the open Model Context Protocol, the server provides a plug‑and‑play, read‑only connection...
HHS Launches Cybersecurity Module Within RISC 2.0 Toolkit
The Administration for Strategic Preparedness and Response (ASPR) has added a cybersecurity module to its Risk Identification and Site Criticality (RISC) 2.0 Toolkit, giving health systems a standardized way to assess cyber risk. The module uses a questionnaire scored against the...
PulsePoint Scales HCP Omnichannel Offering with Reddit Integration
PulsePoint announced an integration that lets healthcare marketers activate its proprietary HCP audience segments directly on Reddit. The self‑serve capability joins PulsePoint’s broader omnichannel ecosystem, enabling coordinated campaigns across social, programmatic display, EHR, DOOH and more. Marketers gain NPI‑level measurement...
Bridgepoint Mulls Options for Defence Investing Strategy
Bridgepoint is evaluating how to position its capital in Europe’s burgeoning defense sector. A recent Carlyle Group white paper projects that the continent could allocate up to €14 trillion to defense and related infrastructure over the next ten years. The magnitude...
WOMEN in ROBOTICS 2026 Awarded by International Federation of Robotics
The International Federation of Robotics (IFR) recognized eleven women in 2026 for their contributions to robotics, highlighting the growing role of female talent in the sector. Global industrial robot installations are expected to exceed 700,000 units by 2028, driven by...
Songs to Put You on Airplane Mode: Finnair Believes Music Should Be as Important as In-Flight Snacks
Finnair has launched a bespoke in‑flight soundscape composed by Finnish composer Lauri Porra, featuring a 12‑track, 45‑minute orchestral suite. The music is timed to each stage of the journey—from boarding to landing—and incorporates traditional Finnish instruments such as the kantele and...
Gaming Marketing Consultancy Open World Acquires Influencer Platform Drope.me to Scale Creator Campaigns
Open World, the marketing consultancy division of Loaded Holdings, has acquired influencer platform Drope.me to add automation and performance‑tracking tools to its gaming creator campaigns. The acquisition enables Open World to scale activations from dozens to thousands of creators simultaneously....
Vantage Aviation Appoints New CFO
Vantage Aviation announced the appointment of Torsten Schneider as its chief financial officer. Schneider joins from APP Jet Center, where he served as CFO of its FBO network, and previously led a finance team of over 25 at a ground‑handling...
Keep Slack Simple and Safeguard Deep Work in 12 Ways
Real‑time messaging in Slack is eroding deep work, with a 2023 Qatalog‑Cornell study showing 45% of workers feel digital tools hurt productivity. The article outlines twelve actionable tactics—ranging from personal Do‑Not‑Disturb schedules to team‑wide quiet‑hour agreements—to protect focus time without...
Marriott Monterey Hotel Receives $75M Refi
Sunshine‑Eichner arranged a $75 million non‑recourse first‑mortgage loan to refinance the Marriott Monterey hotel in downtown Monterey, California. The five‑year, interest‑only loan carries a fixed rate with an all‑in cost below 6% after securing a low‑200s credit spread among 19 competing...
Swedish Agaton Raises $10 Million Seed to Turn Customer Conversations Into Revenue Intelligence
Swedish AI startup Agaton secured a $10 million seed round led by Inception Fund and Alstin Capital to scale its agentic AI platform that transforms everyday customer conversations into real‑time revenue intelligence. The software detects buying intent, sentiment shifts and churn...
PE Weekly: Dealmakers Target the Enterprise—And the Workforce
This week’s middle‑market private‑equity roundup highlighted a wave of strategic acquisitions and a massive fundraising win. New State Capital Partners bought Vast Coworking, expanding its footprint in flexible office space, while Gryphon Investors took a majority stake in HRSoft, a...
Agentic Business Intelligence Startup WisdomAI Shifts From Insights to Action
WisdomAI, an AI‑native business intelligence startup, announced the launch of its Federated Agentic Intelligence platform, shifting its focus from passive insights to autonomous enterprise execution. The platform combines an Enterprise Context Layer, a Model Context Protocol client, and an Adaptive...
Men’s Wearhouse Grows Its Audience Through A Campaign Run Solely On Digital Audio
Men’s Wearhouse partnered with Ovative Group and The Trade Desk’s Kokai platform to run an audio‑only campaign across Spotify, iHeart, Acast and Pandora from March to June 2025. The campaign, aimed at younger “Stylish Steve” and older “Professional Paul” men,...