
Endpoints has launched a daily Pulse Poll to capture biopharma sentiment ahead of the J.P. Morgan Healthcare Conference 2024. The survey asks participants to compare current mood with last year, assess the 2026 risk‑reward balance, and identify the most critical success factor for the sector. It also probes whether the recent rally is fundamentals‑ or sentiment‑driven and records attendance intentions. Responses are anonymous, allowing industry insiders to contribute without attending the event.
Would you wear an AI camera hanging around your neck? @Looki_ai shows off an AI listening and assisting device. My 12th #CES2026 report. What if the data is all yours? Soon many of us will be wearing cameras on glasses. I would, but...

If you’re a student or a professional using AI daily, you’ve seen this happen. A prompt works great today. Tomorrow it gives a weird answer. Next week it breaks after a model update 😅 A prompt that works once for one model isn’t reliable. A...
Advanced Robotics: UC Berkeley This is course is from Peter Abbeel and covers a review on reinforcement learning and continues to applications in robotics. If you work on robotics… this one is worth bookmarking‼️ MDPs: Exact Methods Discretization of Continuous...

Micron unveiled the 3610, a PCIe Gen5 QLC SSD, at CES 2026, marking its first Gen5 G9 QLC client drive and the first single‑sided M.2 2230 offering up to 4 TB. The drive claims sequential reads up to 11 GB/s and writes up to 9.3 GB/s, with...
I was on a call with a Founder the other day. His growth was stuck. So we got to diagnose the issue. The culprit? They had sent 15,000 emails. And got back zero real responses. They tried blogging. Posting online....

The Royal Astronomical Society unveiled its 2026 award winners at the A&G Highlights Meeting on 9 January. Professor Shrinivas Kulkarni received the Gold Medal in Astronomy for pioneering work in time‑domain and multi‑wavelength transient astrophysics, while Professor Andrew Jackson earned the...
Why most AI products fail: Lessons from 50+ AI deployments at OpenAI, Google & Amazon @Aish_Reganti and @KiritiBadam have built 50+ enterprise AI products across companies like @OpenAI, @Google, @Amazon, and @Databricks. Based on these experiences, they’ve developed a small set...
Good morning on this Sunday before #JPM26! I wrote a JPM opener newsletter with some advice for all of you: Chill out. The super-sized gathering of the biopharma universe is important, but it’s not going to make or break the...
SpaceX successfully launched NASA’s Pandora exoplanet telescope aboard a Falcon 9 from Vandenberg, marking the rocket’s fifth first‑stage recovery and a landing on the West Coast. Pandora, a smallsat designed to repeatedly observe 20 known transiting exoplanet host stars, flew alongside...
8 types of LLMs powering modern AI agents — clearly mapped in one visual. From GPTs and MoE to Reasoning Models (LRM), Vision-Language Models (VLM), Action Models (LAM), and Hierarchical Reasoning (HRM), this shows how agents are no longer “just...

SpaceX’s Falcon 9 "Twilight" rideshare launched on Jan. 11 from Vandenberg, deploying 40 spacecraft into a dusk‑dawn sun‑synchronous orbit. The manifest included three NASA astrophysics cubesats—SPARCS, BlackCAT and Pandora—alongside commercial constellations from Kepler Communications, Spire, Plan‑S, Hawkeye 360, Capella Space, ICEYE and Umbra....

French AI ambassador Clara Chappaz called X’s decision to place Grok’s public image‑generation behind a paywall a “scam,” condemning the move as profiteering from illegal deep‑fake sexual content. Malaysia and Indonesia have already suspended Grok, while France, the UK, Australia and...
Researchers at Tsinghua University introduced DrugCLIP, an AI framework that can virtually screen millions of compounds against thousands of protein targets in hours, a speedup of up to ten million times over traditional docking methods. The system converts both molecules...
Online cryptocurrency activity is expanding rapidly, increasing the need for clear analysis of complex blockchain transactions. Justice Trace positions itself as a neutral cyber‑trace investigation platform that reconstructs on‑chain activity without participating in trading or providing financial advice. The brief...

Researchers at Shandong University presented EMIRIS at NDSS 2025, demonstrating that electromagnetic emissions from near‑infrared iris sensors can be captured and used to reconstruct iris patterns. By reverse‑engineering the sensor’s data transmission format and applying a diffusion‑based inverse‑problem solver, the...

The MarkTechPost tutorial walks readers through a targeted data‑poisoning experiment that flips a portion of CIFAR‑10 labels from a chosen class to a malicious class using PyTorch. By constructing parallel clean and poisoned training pipelines with a lightweight ResNet‑18, the...
You need a better reason for someone to act rather than a “better” CTA. • Scarcity is fake. • Urgency is overused. Be clear, specific, and honest. People aren’t dumb, they’re just overloaded with garbage. Stand out by not insulting...
Dear Leaders and experts in fields relating to “Artificial Intelligence” (all types and tools including specifics of how human data is used as the origin or basis for any system design and use) and “Ethics” (meaning formal philosophy, law, policy...

Sender is an email and SMS marketing platform that offers a free‑forever plan with full‑feature access, positioning itself as a low‑cost alternative to legacy ESPs. The service claims a 99.98% inbox placement rate thanks to dedicated sending infrastructure and continuous...
Never hire anyone in sales that doesn't care about money You'll see
Shopify is building the foundation for agentic commerce. Universal Commerce Protocol, which we co-developed with Google, is now live. UCP will make it faster for agents and retailers to integrate. It’s open by default, so platforms and agents can use UCP to...

California's Privacy Protection Agency fined data‑broker Datamasters $45,000 and barred it from selling Californians' personal health information after it failed to register under the California Delete Act. The agency also ordered the firm to delete millions of records by the...
I was recently chatting with Dan Pfister (author of Million Dollar Winback) about the real reasons SaaS companies lose customers. He shared a story of how one SaaS company dropped churn from 18% to 3% by changing who they sold...

Researchers from CAMEL AI, Eigent AI and partners released SETA, an open‑source stack that couples a terminal‑focused toolkit with 400 synthetic reinforcement‑learning tasks. The framework delivers state‑of‑the‑art results on the Terminal Bench benchmark, hitting 46.5% accuracy on version 2.0 with a...
Hiring slowdowns aren’t isolated right now. Many companies are holding headcount flat, protecting capital, and waiting for more clarity before expanding teams. Attrition is also unusually low, which tells you something about uncertainty in the market. 👉 Efficiency, not expansion, is the current...

Researchers at Kyoto University identified a ventral striatum‑to‑ventral pallidum (VS‑VP) circuit that functions as a "motivation brake" suppressing action initiation under stressful conditions. Using chemogenetic inhibition in macaque monkeys, they showed that silencing this pathway restored willingness to start tasks...
Sometimes it’s not what you say, but how you say it. Or, as a brain scientist would would say, how you frame it. The words you choose can make the difference between someone liking your product or not. Someone agreeing...

Space Forge announced the first plasma generation aboard its ForgeStar‑1 satellite, marking the inaugural commercial in‑orbit semiconductor factory. The miniature furnace produced plasma at 1,000 °C, proving that gas‑phase crystal growth can be achieved in low‑Earth orbit. The company plans to...

Google unveiled the Universal Commerce Protocol (UCP), an open standard that lets AI agents handle end‑to‑end shopping experiences. Developed with retailers such as Shopify, Walmart and Target, UCP streamlines discovery, checkout and post‑purchase support across platforms. The protocol will power...

In this episode, Tristan Handy talks with Lauren Anderson, head of Okta's enterprise data platform, about how identity underpins the emerging challenges of AI agents and open data lakes. Lauren explains the need for central governance and a shared semantic...

In the first full week of January, biotech companies collectively raised about $4.9 billion, marking a rapid funding surge ahead of the J.P. Morgan Healthcare Conference. Private‑stage firms attracted roughly $3.2 billion, while publicly listed biotechs secured around $1.7 billion through secondary offerings...
Surgerii Robotics announced a $100 million financing round to accelerate the global deployment of its purpose‑built single‑port surgical robot. The capital infusion, led by leading healthcare venture firms, will fund regulatory approvals, manufacturing scale‑up, and market entry across North America, Europe,...

Data centers now consume about 1.5% of global electricity, and AI‑driven workloads are set to double demand by 2030. Traditional air‑cooling struggles with rising power density, prompting a shift toward liquid cooling, which can remove heat up to 3,000 times...

The 2026 biotech outlook hinges on six pivotal questions that will shape the industry’s trajectory. After a turbulent 2025 marked by regulatory shifts, financing volatility, and rapid scientific advances, stakeholders are reassessing strategies. Key themes include FDA reform, capital availability,...
The Next Generation of Multi-Functional I&I Therapeutics | Ep. 903 How to Pick Winners From a Crowded Cytokine War Bispecifics are everywhere, China biotech is running every combo possible including the ones you have not thought of yet. Trispecifics are next, and...
"If I had 2 more great humans, I'd hire them tomorrow. If they were truly great. But a Pretty Good AI agent is better than ... hiring a human that isn't great. We don't need placeholder hires anymore. AI Agents...

A recent preclinical study links mitochondrial dysfunction to peripheral hypersensitivity, a key driver of migraine attacks. Researchers demonstrated that impaired mitochondrial energy production in trigeminal sensory neurons heightens neuronal excitability and amplifies pain signaling. Using genetically modified mouse models, the...

AI tools aren’t the edge. System design is. Chatbots = interface Automation = leverage Knowledge = memory Data + workflows = ROI Tools are replaceable. Capabilities aren’t. https://t.co/wpNCwkjyBo
I spoke to a founder who sent 15,000 cold emails. The result? Near zero responses. He fired his marketer. Hired an expensive agency. Still zero results. The problem wasn't the execution. It was the STRATEGY. Here is the 6-step GTM framework that works...

Mirador Therapeutics announced a $250 million Series B financing round, led by top venture capital firms. The capital will accelerate its precision‑medicine platform aimed at immune‑mediated diseases. Mirador plans to broaden its R&D pipeline, establish new manufacturing capacity, and recruit leading...
Biotech capital markets are clearly open for business: $2.6B in public FOPO so far in January, the most ever pre-JPM conference. Private VC financings of over >$2B in the same period. Investors clearly have cash to put to work......
Walmart is hedging its AI bets. Gemini from Google, ChatGPT from OpenAI. When consumers start shopping through chatbots, retailers can’t afford to be absent. Link: https://t.co/fjexyHFvSa
#Meningococcal disease has been rare. But when it occurs, it is devastating. High death rate. Survivors often lose limbs, as this person did. There's no way to accurately assess who is at risk. And yet meningococcal vaxes are no longer...
Incredible work by @mikulaja @kontigo_app was at best a naive puppet for sanctions violations At worst a knowing participant. The whole stablecoin industry is on notice Get your AML and Sanctions controls buttoned up or there will be blowback It's when not...

Free tutorial: bulk RNAseq analysis from fastq to GSEA analysis (watch the full playlist) https://t.co/v0UHRSqJ63 https://t.co/LtdxPNYG5Y

Most startups don't fail because they build bad products. They fail because they try to serve everyone. One of the biggest lessons for us this past year at Univid was narrowing down the niche harder - not expanding it. https://t.co/RlCp4pBsvI

Looking at bioinformaticians’ profiles these days, you'd think everyone has decades of experience in cutting-edge single-cell and AI-driven bioinformatics. But something’s missing… 👇 https://t.co/yvmvcwXWyr

Fintech Biz Weekly just dropped: Y Combinator & Coinbase invested in a Venezuelan sanctions evasion app linked to the Maduro regime, including, rumors say, the son of Nícolas Maduro: @kontigo_app The story is a LONG one. You know where...
Build your startup like you’re going to run it forever but prepare it so you could sell it tomorrow. > Organized books > Standardized operations > Product that works without you That’s how you create real leverage with buyers.