News•Jan 9, 2026
GRIm Score Predicts Nivolumab Efficacy in Melanoma
A recent multicenter trial found that the Glasgow Prognostic and Immune (GRIm) score reliably predicts response to nivolumab in advanced melanoma. Patients with high GRIm scores achieved a 45% objective response rate, while low‑score patients showed markedly shorter progression‑free survival. The score, which integrates neutrophil count, lactate dehydrogenase (LDH) and serum albumin, was validated in a cohort of 312 participants across three continents. These findings suggest the GRIm score could serve as a practical, cost‑effective biomarker for immunotherapy selection.
By Bioengineer.org
News•Jan 9, 2026
Novartis to Build Fourth US Radiotherapy Factory in Florida
Novartis announced the construction of its fourth U.S. radiotherapy manufacturing facility, a 35,000‑square‑foot plant in Winter Garden, Florida. The new site is part of the company’s broader $23 billion pledge to expand domestic production across the United States. The factory will...
By Endpoints News
Social•Jan 9, 2026
ROSE Metric: Essential Profitability Gauge for SaaS
Free SaaS Template Fridays 📈 All paths to profitability lead to the ROSE Metric. I created the ROSE Metric years ago, b/c Revenue per FTE can be very misleading. And Rev per FTE is thrown around so much that we've...
By Ben Murray
News•Jan 9, 2026
Tuina Vs. Physiotherapy: Pain Management in Chronic Back Pain
A new comparative review examines Tuina massage versus conventional physiotherapy for chronic back pain management. The analysis cites recent randomized trials indicating both modalities achieve similar reductions in pain intensity for mild-to-moderate cases. Tuina’s manual pressure and meridian focus contrast...
By Bioengineer.org
News•Jan 9, 2026
Smart Leggings Boost Muscle Strength in Seniors
A biotech startup unveiled smart leggings embedded with low‑level electrical stimulation and motion sensors that claim to increase muscle strength in adults over 65. In a 12‑week clinical trial, participants wearing the leggings improved grip strength by 15% and leg...
By Bioengineer.org
News•Jan 9, 2026
2026 FinTech Funding Faces Holiday Hangover
FinTech funding entered 2026 with a post‑holiday lull, recording only six rounds this week. Despite the thin pipeline, three mega‑deals topped $100 million, pushing total capital raised to $734 million. Cyera led the pack with a $400 million Series F that values the AI‑security...
By Fintech Global
News•Jan 9, 2026
BioNTech, UPenn Team up for $50M Seed Fund
BioNTech and the University of Pennsylvania have announced a $50 million seed‑stage venture fund focused on mRNA‑based technologies. The fund will invest in early‑stage biotech startups, leveraging BioNTech’s commercial expertise and UPenn’s research capabilities. By targeting vaccine and therapeutic platforms, the...
By Endpoints News
Social•Jan 9, 2026
AI Landscape Visualized: From ML to Generative Models
Core concepts in Artificial Intelligence — clearly mapped in one visual. From Machine Learning and Deep Learning to NLP, Computer Vision, Reinforcement Learning, Robotics, and Generative Models, this overview highlights how the AI ecosystem fits together and where each discipline...
By Giuliano Liguori
News•Jan 9, 2026
Single-Cell Tests Predict Mycobacterial Infection Outcomes
A new study demonstrates that single‑cell transcriptional profiling can accurately predict outcomes of mycobacterial infections, distinguishing patients who will progress to active disease from those who remain latent. Researchers analyzed thousands of individual immune cells from blood samples, identifying distinct...
By Bioengineer.org
Blog•Jan 9, 2026
Why Your Social Media Growth Stalled (And The Algorithm Isn’t The Problem)
The article debunks the myth that social‑media algorithms are solely to blame for stagnant growth, pointing instead to strategic missteps. It outlines 20 common pitfalls—from creating algorithm‑centric content to inconsistent posting and weak community engagement—and offers concrete fixes such as...
By BloggingWizard
News•Jan 9, 2026
MTHFD2: Key to DNA Repair and LUAD Resistance
Researchers have identified the mitochondrial enzyme MTHFD2 as a pivotal driver of DNA repair mechanisms that enable lung adenocarcinoma (LUAD) cells to survive chemotherapy and targeted therapies. Experimental knockdown of MTHFD2 reduces homologous recombination efficiency and sensitizes tumors to platinum‑based...
By Bioengineer.org
News•Jan 9, 2026
Macy’s to Close 14 Underperforming Stores Even as It Touts ‘Bold New Chapter’ Performance
Macy’s announced the closure of 14 underperforming stores in 12 states as part of its "Bold New Chapter" transformation. CEO Tony Spring highlighted stronger results from the "Reimagine 125" pilot stores and growth in luxury banners Bloomingdale’s and Bluemercury. The...
By Retail TouchPoints
News•Jan 9, 2026
Cloudways in 60 Minutes: The Ultimate in Simplified Cloud Hosting
Cloudways markets itself as a managed cloud hosting platform that simplifies WordPress deployments, offering plans starting at $12 per month. The author completed a full WordPress site setup, including a WooCommerce demo, in under an hour, highlighting the platform’s intuitive...
By TechRadar
News•Jan 9, 2026
Chinese Pseudo-Company Building 3/4 Billion Dollar Rocket Factory
Chinese launch startup Space Epoch announced a 5.2 billion‑yuan ($740 million) factory to mass‑produce reusable, medium‑to‑large liquid‑fuel rockets that can land on sea platforms. The plant, slated to start operations soon, aims to build up to 25 rockets annually, targeting a launch...
By Behind the Black
News•Jan 9, 2026
System Can Diagnose Infections in 20 Minutes, Aiding Fight Against Drug Resistance
Researchers from the UK and China unveiled AutoEnricher, a microfluidic‑Raman platform that identifies bacterial and fungal pathogens in just 20 minutes. Validated on 305 patient samples, the system achieved 95 % accuracy and could detect mixed infections missed by conventional cultures....
By Phys.org – Biotechnology
Blog•Jan 9, 2026
A Bear’s Eye View of the Zanidatamab Data in Gastric Cancer
Jazz Pharmaceuticals presented zanidatamab data from the HERIZON‑GEA‑01 phase 3 trial at the ASCO GI Symposium, targeting HER2‑positive gastric cancer. The company touted the results as practice‑changing, prompting sell‑side analysts to echo the optimism. However, the stock fell 4‑5% as investors...
By Biotech Strategy Blog
Blog•Jan 9, 2026
Amazon Hypes Ambient AI: Always on in the Background
Amazon highlighted its "ambient AI" vision at CES 2026, promising products that operate invisibly until needed. The company also announced Peter DeSantis as head of a new unit covering AGI, custom chips and quantum computing, underscoring a long‑term conviction in breakthrough...
By EcommerceBytes
News•Jan 9, 2026
The Benefits of an Immune-Directed ADC Strategy
Lifordi Immunotherapeutics is pursuing an immune‑directed antibody‑drug conjugate (ADC) strategy that uses the VISTA protein to deliver potent steroids directly to immune cells. VISTA’s rapid internalization allows the ADC to release its payload intracellularly, aiming to avoid the systemic toxicities...
By Pharmaceutical Technology
Social•Jan 9, 2026
Eight Healthcare Tech Trends Shaping 2026 Patient Care
The 8 Biggest Healthcare Technology Trends to Watch in 2026 Healthcare tech is entering a new era: from AI diagnostics to digital wellness, these 8 trends could transform patient care and health management. Read more 👉 https://lnkd.in/e86HpWFZ #HealthTech #AI #FutureOfHealth...
By Bernard Marr
News•Jan 9, 2026
Ultrapex Pro Launches to Support ULTRAPEX Product Layering Across Diverse Usage Scenarios
Ultrapex Pro has been launched as a new application within ULTRAPEX’s evolving application‑layer architecture. The product is positioned as a complementary layer rather than a replacement, aiming to clarify segmentation across diverse usage scenarios. By separating functional components at the application...
By TechBullion
News•Jan 9, 2026
The Infrastructure of Leisure: Engineering Scale and Security for Southeast Asia’s Digital Economy
Southeast Asia’s mobile‑first digital economy is forcing a shift from centralized data centers to edge‑caching architectures to overcome the region’s fragmented, island‑based connectivity. Heavy‑weight leisure apps like Mega888 now push APKs and OBBs to micro‑data centers near users, slashing latency...
By TechBullion
Social•Jan 9, 2026
Latent Demand: Unseen Needs Outpace Traditional Unmet Wants
The concept of the problem-unaware buyer is a long-standing one, especially in tech, where the dream is to unlock and dominate a whole new market through innovation. It falls often into the category of latent demand - a very real...
By Liam Moroney
News•Jan 9, 2026
How Utility-Driven Crypto Presales Are Evolving in 2026
Crypto presales in 2026 have shifted from speed‑driven fundraising to utility‑focused models. Investors now demand clear token functions, realistic use cases, and phased funding structures rather than speculative hype. Projects that embed their token in payments, access or ongoing services...
By TechBullion
News•Jan 9, 2026
Hyper-Personalisation Reshapes the Future of WealthTech
Wealth management is undergoing a shift toward hyper‑personalisation, where advice is continuously tailored using real‑time data, predictive analytics, and behavioural insights. IntellectAI’s research highlights that over 70% of high‑net‑worth individuals tie personalised advice to firm loyalty, yet many firms still...
By Fintech Global
News•Jan 9, 2026
Hacker Behind Wired.com Leak Now Selling Full 40M Condé Nast Records
A hacker using the alias “Lovely” is now offering nearly 40 million Condé Nast user records for sale, expanding on a prior leak of 2.3 million Wired.com accounts. The alleged dataset spans dozens of Condé Nast‑owned sites, including high‑traffic titles such as Vanity Fair,...
By HackRead
News•Jan 9, 2026
AAAI Presidential Panel – AI Reasoning
The panel, moderated by former AAAI President Francesca Rossi, examined AI reasoning as outlined in the AAAI’s 2025 Future of AI Research report. Experts Holger Hoos and Subbarao Kambhampati discussed how to define and implement reasoning in AI, emphasizing planning...
By AIhub
Social•Jan 9, 2026
Boost Growth by Optimizing Customers, Churn, and Sales Focus
Best things to do when .. you don't know what to do: 1/ More time w/existing customers. Meet 5/mo IRL. 5/week on Zoom. 2/ Hire 1 great VP 3/ Drive down churn. You grow faster even w/o more leads 4/ Join more sales calls....
By Jason Lemkin
News•Jan 9, 2026
Digital Wealth Management: Three Trends Reshaping 2026
European wealth managers face heightened volatility, tighter regulation, and soaring digital expectations in 2026. Firms must translate abundant market data into clear, confidence‑building insights through scalable digital platforms. A premium experience now depends on intuitive interfaces, seamless onboarding, and truly...
By Fintech Global
Social•Jan 9, 2026
Dashboards Show History, Not Growth Opportunities
the problem with dashboards: they don’t tell you where to grow. They tell you where you’ve been. Mid-market teams don’t lack data. They have plenty of dashboards: CAC. LTV. Funnel conversion. Segment performance. I remember attending a weekly meeting w/...
By Anna Furmanov
News•Jan 9, 2026
Krystal Biotech Says It Can Deliver Native Protein to Cystic Fibrosis Patients
Krystal Biotech announced early data showing its mutation‑agnostic platform can deliver functional native CFTR protein to the lungs of cystic fibrosis patients. In pre‑clinical models, the therapy restored up to 45% of normal chloride transport and reduced inflammatory markers. The...
By Endpoints News
News•Jan 9, 2026
Insmed Jumps on ‘Blowout’ Sales Beat for Bronchiectasis Drug Brinsupri
Insmed reported that its newly approved bronchiectasis therapy Brinsupri generated $144.6 million in Q4 2025 sales, nearly three times analyst forecasts. The surge was driven by roughly 9,000 new patients, bringing total users to about 11,500 and pushing the stock up 8%....
By BioSpace
Blog•Jan 9, 2026
Baker Hughes Invites Brian Solis to Keynote Its Annual Meeting in Florence, Italy
Baker Hughes has invited digital futurist Brian Solis to deliver the keynote at its 2026 Annual Meeting in Florence, Italy. The event, now in its 27th year, will spotlight "The Next Industrial Renaissance: Unlocking Human Potential in the Age of...
By Brian Solis
News•Jan 9, 2026
Tim Kosiba Named NSA Deputy Director
Timothy Kosiba has been appointed the National Security Agency’s 21st Deputy Director, a role confirmed by President Donald J. Trump after designation by Secretary of War Pete Hegseth and DNI Tulsi Gabbard. Kosiba returns as the agency’s most senior civilian...
By SecurityWeek
News•Jan 9, 2026
Affirmative Becomes Nacha Preferred Partner
Nacha announced that Affirmative, a leading ACH risk‑management, compliance and fraud‑monitoring provider, has become a Nacha Preferred Partner for Compliance, Fraud Monitoring, Risk and Fraud Prevention. The partnership gives banks and credit unions a centralized view of both originated and...
By Finextra
News•Jan 9, 2026
Prometeo Joins FDATA
Fintech infrastructure provider Prometeo has joined the Financial Data and Technology Association (FDATA), expanding the trade group’s roster to more than 30 members across the United States and Canada. Prometeo offers bank connectivity, account verification, payment initiation, and data‑access services...
By Finextra
News•Jan 9, 2026
OWASP CRS Flaw Lets Encoded Attacks Slip Past WAFs
A critical vulnerability (CVE-2026-21876) in the OWASP Core Rule Set lets attackers bypass charset validation, enabling encoded XSS payloads to slip past web application firewalls. The flaw resides in rule 922110, which only inspects the final part of multipart requests,...
By eSecurity Planet
News•Jan 9, 2026
Mollie Becomes European Payments Initiative Principal Member
Mollie has become a Principal Member of the European Payments Initiative (EPI) and will launch the Wero unified payment solution on its platform. As a Principal Member, Mollie will connect merchants directly to the real‑time, account‑to‑account Wero network, which aims...
By Finextra
Social•Jan 9, 2026
UCB Should Demand Label Change; Sonelokimab Inferior
“THAT WILL DECIMATE THE COMPETITION” If the FDA is dumb enough to put a 29% delta on the $MLTX label, UCB should simply request a label change to include *their* P2 efficacy data on the label….where their delta was ***36%***. 36>29 for...
By Adam May
Social•Jan 9, 2026
Zero‑downtime Migration of 5+ PB From AWS to On‑prem
Jeremy, a 19-year veteran of 37signals, calmly walks through the process moving 5+ petabytes of data and billions of individual files off AWS and onto our own on-prem storage setup without a second of downtime. The how, the time, and the...
By Jason Fried
News•Jan 9, 2026
The Future of Personal Injury Law: AI and Legal Tech in Philadelphia
Philadelphia personal injury firms are rapidly integrating AI and legal tech, especially predictive analytics, to enhance case management and outcome forecasting. These tools enable lawyers to analyze vast datasets, assess risks, and develop evidence‑based strategies, shifting practice from intuition to...
By Artificial Intelligence News
Social•Jan 9, 2026
CHIP Clones Raise Cardiovascular Risk in Cancer Survivors
More evidence that blood stem cell clones (CHIP), common with increasing age, increase the risk of cardiovascular events, from people treated with cancer https://t.co/56YDjxshjg https://t.co/kdUksoCFmI
By Eric Topol
Social•Jan 9, 2026
Red Blood Cells Drive Vascular Damage in Long‑Term Type 2 Diabetes
Implicating red cells as an underpinning of the vascular damage seen with long duration Type 2 diabetes https://t.co/FzvmreCtn7 https://t.co/MdgpHmpRvo
By Eric Topol
Social•Jan 9, 2026
Anthropic's Provider Lockdown Seen As Customer Hostility
I love the models Anthropic are offering, but I seriously hope it's a mistake that they're blocking alternative harness providers, like @opencode, from working with their subscriptions. Seems very customer hostile. https://t.co/afxEQ0XTFb
By David Heinemeier Hansson
Social•Jan 9, 2026
Nominate Under‑35 Biotech Trailblazers for 2026 Award
Do you know an up and coming someone killing it in biotech? If they're under 35 years of age, please nominate them for the 2026 Technology Review 35 Innovators Under 35 Award. (or just email me. address is in bio) https://t.co/90fwj4GjNU
By Antonio Regalado
Social•Jan 9, 2026
Eric Schmidt's Foundation Launches New Observatory System
Former Google CEO Eric Schmidt announced late Wednesday that @schmidtsciences, one of his philanthropies, would build the Eric and Wendy Schmidt Observatory System. https://t.co/MJJA9jqN9O
By Payload
Social•Jan 9, 2026
Zanidatamab Gastric Cancer Data Faces Seven Bearish Concerns
It's good to see new trial readouts at #GI26, although there are 7 reasons to be bearish about the zanidatamab data in gastric cancer: https://t.co/g2MbrPI7Iu https://t.co/tBY2yJ6YMe
By Sally Church
Social•Jan 9, 2026
Stablecoins Fuel Illicit Activity, Undermining U.S. Sanctions
Stablecoins dominate illicit crypto activities, eclipsing Bitcoin Sanctions architecture challenged: Stablecoins providing dollar liquidity to sanctioned actors. Geopolitical irony - U.S.-based stablecoins undermining U.S. financial sanctions effectiveness. Regulation can't stop what's already on-chain https://t.co/3msm9cw1YP
By Efi Pylarinou
Social•Jan 9, 2026
APOE Ε3/Ε4 Alleles Drive Majority of Alzheimer’s Cases
A new report claims that the APOE gene alleles accounts for the vast majority of Alzheimer's cases: "Without strong underlying risks from APOE ε3 and ε4, almost all AD and half of all dementia would not occur." https://t.co/KgRFx36WOn
By Eric Topol
Social•Jan 9, 2026
Linking DNA Mutations to Gene Expression in Single Cells
Genotype-to-phenotype mapping of somatic clonal mosaicism via single-cell co-capture of DNA mutations and mRNA transcripts https://t.co/6Lss1ukbvp https://t.co/bGwnmQEYfI
By Ming Tang
Social•Jan 9, 2026
AI-Driven Efficiency Fuels Flat Hiring and Lean Teams
Noticing fewer job openings in 2026? Big companies like Shopify and Chime are keeping headcount flat. 66% of leaders want to stay pat or even cut roles. Why? Uncertainty, a focus on capital efficiency, and a big bet on AI driving productivity. Lean teams...
By Eric Siu