
Rapid growth of biosimilars is reshaping retinal therapeutics, with ranibizumab biosimilars already market leaders and aflibercept biosimilars poised to follow. The two drugs differ fundamentally in manufacturing: ranibizumab is produced in Escherichia coli, requiring complex refolding of inclusion bodies, while aflibercept is expressed in CHO cells, enabling proper folding and glycosylation. These divergent platforms affect yields, cost, and process variability, giving aflibercept biosimilars a manufacturing advantage. Consequently, production efficiency may become as decisive as clinical equivalence for market uptake and patient access.

A recent study highlights additive manufacturing as a flexible alternative for producing bespoke bioreactors used in cell and gene therapy. Unlike traditional injection‑molded single‑use devices, 3D printing allows unlimited shape and size changes without new molds. Although per‑part costs are...

Within weeks, two state Departments of Human Services suffered separate data breaches, exposing personal information for nearly one million residents. In Illinois, a misconfigured map inadvertently displayed details of about 700,000 individuals, including Medicaid recipients, while Minnesota’s MnCHOICES system was...

Google Search Console treats a URL that appears in both an AI Overview and the traditional blue‑link list as a single impression. John Mueller confirmed that the platform aggregates multiple appearances of the same URL on a SERP into one...

Small merchants often see strong sales but still struggle with cash flow because money leaves their business long before it returns from credit‑card settlements and inventory turnover. About 60 percent of SMBs report this timing gap as a primary financial pain...
U.S. consumers in 2025 prioritized smaller discretionary purchases—used goods, apparel, and dining—over big‑ticket items like electronics, furniture, and travel, according to Bank of America Institute data. A weakening labor market and waning sentiment drove this cautious behavior, a trend Moody’s...

SEC Chairman Paul Atkins praised Israel’s innovation ecosystem during a speech at the Tel Aviv Stock Exchange. He emphasized that Israel generates the highest number of startups per capita and ranks second globally in venture‑capital per capita, despite its small...

At Pharmapack 2026, ACG Packing unveiled SuperPod™, a new cold‑form blister laminate that reduces cavity size by up to 39% and triples the number of blisters per shot. The multi‑layer construction enables deeper draws without compromising the aluminum barrier, cutting material...

Johnson & Johnson downplayed the impact of the new Most‑Favored‑Nation (MFN) pricing clause on its earnings, asserting that existing contracts and a diversified portfolio cushion any downside. The company projected a robust growth trajectory through 2026, driven by its oncology...

OpenAI’s CFO Sarah Friar outlined a rapid monetization push, linking a three‑fold increase in compute capacity to a surge in annual recurring revenue that topped $20 billion in the last year. The company now faces $1.4 trillion of spending commitments through 2034,...
Researchers at NUS Medicine identified the transcription factor DMTF1 as a key driver of neural stem‑cell function in the aging brain. Experiments using human‑derived and telomere‑dysfunctional stem cells showed that DMTF1 levels drop with age, and restoring its expression revives...
Oracle has disclosed CVE‑2026‑21962, a critical flaw in its Fusion Middleware WebLogic proxy plug‑ins that permits unauthenticated attackers to compromise Oracle HTTP Server over HTTP. The vulnerability affects Oracle HTTP Server versions 12.2.1.4.0, 14.1.1.0.0 and 14.1.2.0.0, as well as the...

OpenEvidence, a Miami‑based AI medical search platform, closed a $250 million Series D round that doubled its valuation to $12 billion. The funding, led by Thrive Capital and DST with participation from GV, Sequoia, Kleiner Perkins and Coatue, brings total capital raised to...

Tanabe Pharma announced that its oral melanocortin‑1 receptor (MC1R) agonist achieved its primary endpoint in a Phase 2 trial for a rare blood disorder, delivering a 60% response rate among patients. The pill offers a non‑injectable option that could reduce transfusion...

Ollama, the platform for running AI models locally, has launched an experimental image‑generation feature for macOS. The initial release includes two models: Alibaba’s Z‑Image Turbo, a 6‑billion‑parameter photorealistic generator, and Black Forest Labs’ Flux 2 Klein, offered in 4‑billion and 9‑billion‑parameter variants....

Barnes & Noble reversed its decline by re‑imagining stores as community‑focused bookshops rather than traditional retailers. After hitting a low of roughly 600 locations, the chain opened 60 new stores in 2025 and plans another 60 in 2026, bringing its...

A new arXiv study proposes deploying radio dishes on the Moon to create an Earth‑Moon interferometer capable of sub‑microarcsecond resolution. By leveraging the lunar radius as a baseline, the array could resolve black‑hole shadows as small as one‑tenth of a...

Bloomingdale’s is turning its Carousel space at the 59th Street flagship into a Wuthering Heights‑themed shop through Feb 22, 2026. The activation features a 35‑piece exclusive Aqua collection plus licensed items from Hanky Panky, Slip, Art of Tea, Maude’s and Dear...

CyberNut, a Miami‑based startup, closed a $5 million minority growth equity round led by Growth Street Partners to scale its K‑12 cybersecurity awareness platform. The company, which emerged from stealth in May 2024 after raising $800,000 in pre‑seed capital, already serves over...

Aliisa Rosenthal, OpenAI’s first sales leader, has become a general partner at venture‑capital firm Acrew Capital. During her three‑year stint at OpenAI she built an enterprise sales organization that launched products such as DALL·E, ChatGPT, and Sora. Rosenthal says AI startups...

IntraBio announced that its experimental therapy for ataxia‑telangiectasia (A‑T) achieved statistically significant improvement in motor function in a pivotal Phase 3 trial. The study met its primary endpoint and demonstrated a favorable safety profile across a genetically defined patient cohort....
Johnson & Johnson reported a 9.1% rise in fourth‑quarter sales to $24.6 billion and projected full‑year revenue of $100‑101 billion for 2026, up from $94.2 billion. The company’s growth is driven by strong cancer and immune‑therapy sales, offsetting a steep decline in its...
The article argues that AI knowledge bases must go beyond listing policies and include explicit "don’ts" to prevent harmful behavior. By integrating negative examples, decision‑logic trees, and relational knowledge graphs, organizations can give agents contextual guardrails and judgment akin to...
University of Oxford engineers quantum‑enabled proteins, creating magneto‑sensitive fluorescent proteins (MFPs) that respond to magnetic and radio‑frequency fields when illuminated. Published in Nature, the study demonstrates deliberate design of quantum mechanical processes inside biomolecules, moving beyond observation of natural quantum...

The UK government has launched the £20 million Westcott Space Hub in Buckinghamshire, a 62,000‑sq‑ft facility designed to accelerate space‑technology development. Backed by the UK Space Agency and a mix of public and private partners, the hub offers testing infrastructure, collaborative...

AppOmni released an ROI report showing SaaS security delivers tangible operational benefits quickly. Customers reported saving roughly 146 manual hours each month and a 24% reduction in audit findings after gaining visibility. The study found measurable value within two weeks...

The Vigx π6 is a lightweight, AI‑powered exoskeleton that assists walking, standing and light fitness activities. Weighing just 2 kg and folding to umbrella size, it uses a built‑in camera and AI processor to analyze terrain and modulate power every 30 milliseconds, improving...

At Davos, Google DeepMind CEO Demis Hassabis said there are no plans to embed advertisements in its Gemini AI assistant. This contrasts with OpenAI, which announced it will pilot ads in the free and Go versions of ChatGPT, sparking user...

Zucora, Canada’s leading home‑furnishing protection provider, has launched Champions, an AI‑driven, mobile training platform for retail sales associates, offered free to its SmartOne partners. The platform delivers bite‑sized, gamified modules, virtual webinars, and a points‑based incentive system that rewards learning...
Gartner forecasts that by 2028 fewer than 20 companies will move humanoid robots from pilot projects to full‑scale production in manufacturing and supply‑chain environments. While chief supply‑chain officers are attracted to the human‑like form factor for labor‑cost challenges, the research...
Researchers at MD Anderson and Stanford engineered bispecific nanobodies that anchor viral particles to the respiratory mucus, boosting the airway’s first‑line defense. In preclinical mouse models the nanobodies reduced infection rates for influenza and SARS‑CoV‑2 and cut viral transmission. The...
Northwestern researchers have demonstrated that in multi‑user quantum communication networks, increasing the amount of shared entanglement can paradoxically degrade overall fidelity when each pair routes selfishly. By modeling non‑cooperative routing decisions, they showed that mixed entangled states generate a quantum...
The Biotech CEO Sisterhood’s pink‑themed gathering at the J.P. Morgan Healthcare Conference drew up to 1,000 participants, underscoring a growing movement to spotlight women executives in biopharma. Since its 2022 launch, the group has expanded to about 350 members and...

WebCatalog lets users convert any website into a standalone desktop application for macOS and Windows, offering a centralized hub that eliminates browser tab overload. The platform bundles features such as ad and tracker blocking, app‑level passwords, cloud sync, and customizable...
Michaels CEO David Boone says the retailer’s top priority is seizing market share left by Party City and Joann’s exits. The chain has rolled out a Party Shop and Knit & Sew section in every store, added balloon bars, and plans to...
India's indigenous UAV maker ideaForge will display its tactical drone ZOLT at the 77th Republic Day Parade, highlighting the country's push for homegrown defence solutions. ZOLT is a multi‑role, VTOL‑capable platform built for long‑range ISR and precision payload delivery in...

Attackers are abandoning noisy, brute‑force attacks for stealth‑first, multi‑stage malware that can linger for weeks. OPSWAT telemetry shows a 127% rise in malware complexity and an increase from eight to 18 behavioral nodes per sample in six months. Traditional signature‑based...

Ars Technica tested the free‑tier versions of OpenAI’s ChatGPT 5.2 and Google’s Gemini 3.2 Fast across eight diverse prompts, ranging from dad jokes to technical instructions. Gemini secured four wins, ChatGPT three, with one tie, highlighting Gemini’s gains in clarity, factual depth, and...
JAXA released preliminary findings on the December 2025 H3 launch failure, pinpointing premature fairing separation that damaged the satellite mounting section and ruptured the second‑stage fuel tubing. The damage halted engine combustion and caused the Michibiki‑5 satellite to detach when...

A sophisticated loan‑phishing campaign in Peru, uncovered by Group‑IB, uses fake loan applications to harvest valid bank card numbers and six‑digit PINs. The operation impersonates a leading Peruvian bank across 16 dedicated domains and more than 370 related sites, employing...

Upscale AI announced a $200 million Series A round led by Tiger Global, Premji Invest and Xora Innovation, taking its total financing above $300 million and earning unicorn status just months after a $100 million seed. The capital will accelerate the rollout of its...

Novo Nordisk announced a strategic deal to acquire Aspect Biosystems, a 3‑D bioprinting company specializing in cell‑based therapies. The acquisition aims to accelerate Novo's development of encapsulated beta‑cell products for type 1 diabetes, leveraging Aspect's platform to scale manufacturing. Financial terms...

Tonic.ai has added upsert capabilities to its test‑data platform, allowing teams to insert new records while updating existing ones without overwriting valuable test data. The feature supports preserving legacy fixtures, merging multiple data subsets, and retaining mock data for unreleased...
Check Point unveiled Exposure Management, a platform that fuses threat intelligence, vulnerability prioritization, and automated remediation into a single workflow. The solution offers real‑time situational awareness by correlating dark‑web insights, exploitability context, and attack‑surface visibility. It integrates with more than...

Microsoft Research unveiled Rho-alpha, the first robotics model built on its Phi vision-language series, extending capabilities with tactile sensing and bimanual manipulation. The model translates natural‑language commands into control signals, co‑training on physical demonstrations, simulated tasks, and web‑scale visual question‑answering...

Constant Contact’s 2025 Small Business Now survey highlights five marketing trends that will shape small‑business success in 2026. Email continues to deliver the highest engagement, even as only 41 % of owners view it as their primary channel. Social media is...

KalVista secured FDA approval for its oral on‑demand hereditary angioedema drug Ekterly after a delayed PDUFA review and reported political pressure. The pill is positioned as the only oral option in a market dominated by injectable therapies, targeting the $3.8‑6.5 billion...
Channel99 unveiled an AI‑driven Paid Search Optimization tool aimed at B2B marketers, shifting measurement from click‑based metrics to cost‑to‑engage target accounts. The platform scores keywords and ad groups by their ability to reach ideal customers, surfacing waste and recommending budget...

Spanish family-owned Zamora Company has appointed creative agency Motel to develop an integrated global campaign for its premium limoncello brand, Villa Massa. The partnership follows Zamora’s €2 million investment to double production capacity at its Sorrento plant, targeting expansion into the...