Technology Social Media and Updates

Predicting Late‑Stage Trial Outcomes Could Speed Drug Development
SocialMar 30, 2026

Predicting Late‑Stage Trial Outcomes Could Speed Drug Development

Accurately predicting success and failure rate of late stage trials for new drugs could legitimately accelerate pharma. The late stages are where most of the time and money go, and are a bottleneck on bringing drugs to market today.

By Ramez Naam
Prediction Claims 100% Success for MLTX in Psoriatic Arthritis
SocialMar 30, 2026

Prediction Claims 100% Success for MLTX in Psoriatic Arthritis

Really interesting. One of their predictions is 100% success chance for $MLTX in psoriatic arthritis.

By Peter Suzman
LLMs Now Threatening Software Security, Experts Confirm
SocialMar 30, 2026

LLMs Now Threatening Software Security, Experts Confirm

Thomas on LLMs vis software security, or, the thing that has been theorized for years is now, in the judgement of local domain experts, actually happening.

By Patrick McKenzie
Google Search Console Reports Spike on Merchant Filters
SocialMar 30, 2026

Google Search Console Reports Spike on Merchant Filters

ICYMI: Google Search Console performance reports spiking for some filters, like merchant/product filters https://t.co/R8urwCAUnm https://t.co/uVdoDw9I5u

By Barry Schwartz
Amazon Aims to Win the Ad Game
SocialMar 30, 2026

Amazon Aims to Win the Ad Game

Amazon is playing to win in advertising $AMZN The LightShed Podcast, Ep. 306. With @BrandoLightShed and @WaltLightShed https://t.co/Pzx5rhEa8x

By Rich Greenfield
Top AI Coding Agent Ignored Despite Benchmark Victory
SocialMar 30, 2026

Top AI Coding Agent Ignored Despite Benchmark Victory

Built an AI agent that took #1 on Terminal-Bench 2.0 — "the industry benchmark for coding agents". 82.0% across 445 trials. Validated by the maintainer 3 days ago. "Ready to merge." Still not on the leaderboard. LinkedIn DM — no response. Discord —...

By Aleksei Petrov
New Have I Been Pwned Features Boost Privacy, Usability, Performance
SocialMar 30, 2026

New Have I Been Pwned Features Boost Privacy, Usability, Performance

Today, after many months of hard work, we're launching a bunch of new @haveibeenpwned features that improve privacy, usability and performance. We're a little team, but we've done a lot since this pic in November. Here are all the details:...

By Troy Hunt
Enterprise Agentic AI Signal Gets Major Refresh
SocialMar 30, 2026

Enterprise Agentic AI Signal Gets Major Refresh

I’m in the midst of a major refresh of my Agentic AI Signal for the Enterprise🚨 New vendors arriving. Major new capabilities emerging. Entirely updated platform rankings. Still the most comprehensive assessment of enterprise agentic AI platforms + the landscape just changed.🤖 https://t.co/KBHkBfIhdu

By Dion Hinchcliffe
Scale with SAP Business One, Ditch Manual Entry
SocialMar 30, 2026

Scale with SAP Business One, Ditch Manual Entry

Stop the manual entry race. 🏎️ SAP Business One shifts you to agentic oversight, giving you the control to scale. Check the blog: https://t.co/YT5H1uDNYW #SAPBusinessOne #Manufacturing #ERP #SupplyChain #Wholesale $SAP https://t.co/rFoq85DRI4

By David Strausser
Diagram Mislabels PrSM: Shows Liquid Engine, Not Solid
SocialMar 30, 2026

Diagram Mislabels PrSM: Shows Liquid Engine, Not Solid

This exploded diagram appears to shows a liquid propellant rocket engine (two tanks, plus an engine); PrSM is a solid rocket motor. What gives? https://t.co/GvxUeeiaqs

By Jeffrey Lewis
Apple Metal Direct Inference Threatens NVIDIA's Software Moat
SocialMar 30, 2026

Apple Metal Direct Inference Threatens NVIDIA's Software Moat

1/ It's amazing to see consumer hardware do inference on gigantic models, but that's not the big deal. @danveloper went straight to the Apple metal with Claude help, circumventing all the frameworks. NVIDIA's software moat may be now easily breakable, via ......

By Vijay Pande
Only 38% Believe AI Progress Matches Their Expectations
SocialMar 30, 2026

Only 38% Believe AI Progress Matches Their Expectations

Something extremely funny to me about this poll showing that 38% of Americans say the pace of AI development is happening roughly in line with their estimates. https://t.co/MoKRVrsRKY https://t.co/Wrnpsj1pp7

By Joe Weisenthal
China Unveils Modular Humanoid Robot with Interchangeable Heads
SocialMar 30, 2026

China Unveils Modular Humanoid Robot with Interchangeable Heads

Meet Xiaoling: China’s Modular Humanoid #Robot with Swappable Heads and Multi-Role Capabilities by @StarSnap_1 #Robotics #Engineering #ArtificialIntelligence #Technology https://t.co/m7OjhgGMrY

By Ron van Loon
AI Success Hinges on QA and DevOps Maturity
SocialMar 30, 2026

AI Success Hinges on QA and DevOps Maturity

RT 77% of orgs are confident in AI outputs? while many still lack secure CI/CD, automated audit trails, and even basic defect escape metrics. Your QA and DevOps maturity will make or break AI agents in production. #AI #DevOps #QA @Star_CIO ...

By Isaac Sacolick
ARC-AGI-3 Designed for Zero AI Score, Watch Progress
SocialMar 30, 2026

ARC-AGI-3 Designed for Zero AI Score, Watch Progress

This is true, but ARC-AGI-3 is also a test designed so that AI gets zero today, just as the earlier ARC-AGI tests were designed . Those tests were then mostly saturated with a year or two. The thing to watch with...

By Ethan Mollick
Peptides Shift From Biomarkers to Feeling Control, Raising Risks
SocialMar 30, 2026

Peptides Shift From Biomarkers to Feeling Control, Raising Risks

I think peptides are popular because they give people a feeling of power and control. One feels helpless when they can't sleep, stop scrolling, eat well or exercise consistently. A few injections wrestles back a feeling of control. Evidence...

By Bryan Johnson
Discussing AI-Driven Wireless Evolution From 5G to 6G
SocialMar 30, 2026

Discussing AI-Driven Wireless Evolution From 5G to 6G

Tomorrow I'll be speaking on the @FierceNetwork_ Virtual Research Summit: AI-driven wireless: From 5G to 6G. I'll be joining the likes of @malleven33 @RogerEntner @chetansharma and others. Details here: https://t.co/U97rmogo5N JOIN ME!

By Mike Dano
90-Day AI Sprint Gives CEOs Exponential Competitive Edge
SocialMar 30, 2026

90-Day AI Sprint Gives CEOs Exponential Competitive Edge

The 90-Day Sprint to Exponential Advantage: A CEO’s AI Integration Playbook by @Timothy_Hughes https://t.co/NVCiMQZBWN @DLAIgnite #SocialSelling #DigitalSelling #Leadership #ArtificialIntelligence #Tech #TechNews #AgenticAI #AIAgents #Agentic #AI #FutureOfWork #Strategy https://t.co/23V7UWSB4O

By Tim Hughes
Setidegrasib’s KRAS Degradation Still Unproven in Cancer
SocialMar 30, 2026

Setidegrasib’s KRAS Degradation Still Unproven in Cancer

Elegant in theory, unproven in practice: setidegrasib and the case (or not) for KRAS degradation in NSCLC and pancreatic cancer: https://t.co/NuaOJ2amgn https://t.co/i9FpK4W19W

By Sally Church
Claude Is a Tool, Not the AI Itself
SocialMar 30, 2026

Claude Is a Tool, Not the AI Itself

Dear non-technical folks: Repeat after me👇 Claude is NOT AI Claude is an app built with AI models Claude runs on LLM like claude 3 opus Claude is the tool u interact with, while LLM is the underlying AI model that powers it AI is...

By Omozara
Turn Spreadsheets Into Live AI Dashboards Instantly
SocialMar 30, 2026

Turn Spreadsheets Into Live AI Dashboards Instantly

Fastest way to build a business dashboard with AI in 2026: ↓ 1// Take any spreadsheet you already use to track business data. Revenue, leads, whatever you've been tracking manually. 2// Open Claude Code and tell it you want a live dashboard...

By Ev Chapman
AI Recreates Real Conversations Using Your Past Recordings
SocialMar 30, 2026

AI Recreates Real Conversations Using Your Past Recordings

This AI lets you have a real conversation with anyone. Upload her voicemails, old videos, phone recordings. Pantio builds a persona that sounds, talks and gives advice like a real person

By Hasan Toor
M365 Copilot Council Lets You Compare Multiple AI Models
SocialMar 30, 2026

M365 Copilot Council Lets You Compare Multiple AI Models

New in M365 Copilot: Council. You can run multiple models on the same prompt at the same time, so you can see where they align and diverge, and understand what each adds. https://t.co/2p7O14OLFp

By Satya Nadella
Start AI Projects with Clear Objectives, Then Structure Folders
SocialMar 30, 2026

Start AI Projects with Clear Objectives, Then Structure Folders

The simplest mistake I’ve seen consistently with creating AI project folders is doing so with no concrete direction. You always need to start with an objective in mind. Once you have the objective, the structure follows. EX - Here’s my setup...

By Davie Fogarty
Match Guest Post Style to Audience for Maximum Reach
SocialMar 30, 2026

Match Guest Post Style to Audience for Maximum Reach

RT @InspireToThrive Do they like personal stories, step-by-step advice, or opinion pieces? Read the full article: Writing Guest Posts for Blogging That Actually Grow Your Reach ▸ https://t.co/Fa7HOkHaR4

By Tom Pick
Self‑evolving Software and Meta‑harnesses Will Soon Evolve Themselves
SocialMar 30, 2026

Self‑evolving Software and Meta‑harnesses Will Soon Evolve Themselves

All software will be self-evolving soon. Meta-Harness is AutoResearch but for the agent harness itself. Imagine the meta-harness self-evolves as well.

By Matthew Berman
GamePal App Helps You Finally Finish Games
SocialMar 30, 2026

GamePal App Helps You Finally Finish Games

Much like with books, I start way too many video games and never finish them. This week's ⚡ Hiro Report features an app that finally solves that (@gamepalapp)... plus: → Akai's new portable beat maker that rivals the TE K.O. II → A...

By Hiro (Hiro Report)
Copilot M365 Disappointed Early Adopter Calls It Massive Fumble
SocialMar 30, 2026

Copilot M365 Disappointed Early Adopter Calls It Massive Fumble

I'm turning off Copilot M365. I was an early adopter and kept hoping for it to become something. After working with Manus for a week to work with my outlook its obvious I've been duped. Copilot M365 is such a...

By Mark Davis
Survive Q2: Validate Offer, Refresh Creative, Know Break‑Even ROAS
SocialMar 30, 2026

Survive Q2: Validate Offer, Refresh Creative, Know Break‑Even ROAS

Operators enter Q2 with the same targets they exited Q1 with. CPMs are about to rise 20-35% Creative fatigue compounds faster And the brands that survive it answered these 3 questions before April 1: 1. Does your offer convert at current CPMs...

By Kody Nordquist
Final Call: AI Coding Bootcamp Enrollment Ends Tomorrow
SocialMar 30, 2026

Final Call: AI Coding Bootcamp Enrollment Ends Tomorrow

Final call — the AI Coding Bootcamp closes enrollment tomorrow. We've been talking about this program for the past two weeks. Tomorrow — March 31 — is the last day to apply. 50 seats. First cohort. Once enrollment closes, it...

By Ryan Allis
Automate HR Tasks, Focus on Leading Your Team
SocialMar 30, 2026

Automate HR Tasks, Focus on Leading Your Team

Employee requests shouldn't be a full-time job. Factorial HR automates time-off and documents so you can get back to leading your team. #HRTech #Factorial #Efficiency Schedule a meeting with me: https://t.co/ZsEwnG4p2n https://t.co/qXGdTm9Uzt

By David Strausser
Local Edge Data Boosts Safety Through Faster Action
SocialMar 30, 2026

Local Edge Data Boosts Safety Through Faster Action

Resilience doesn’t sit in the server room. It’s in the hands of the people who depend on low-latency to stay safe 🤝 See how Edge Control + T-Platform keeps data local, cuts latency, and helps teams act faster.↙️ https://t.co/wxAE44qfmi @TMobileBusiness Partner #EnterpriseResilience #DutyOfCare #EdgeControl...

By Prof. Sally Eaves
Use AI as Tutor, Not Shortcut, With Guardrails
SocialMar 30, 2026

Use AI as Tutor, Not Shortcut, With Guardrails

"How much should I use AI? What should I use it for?" This research project with students at UC Berkeley revealed some great insights: Use as a tutor (not a shortcut), build guardrails to protect learning, know when to turn...

By Richard Seroter
Democratic Oversight Essential to Prevent AI’s Anti‑human Future
SocialMar 30, 2026

Democratic Oversight Essential to Prevent AI’s Anti‑human Future

From early employee at Facebook @rosenstein and co-inventor of “Like” button affirming the core problem presented in “The AI Doc” about the reckless race driving an anti-human future. Justin offers clear recommendations on how we need more democratic control, ownership...

By Tristan Harris
Krikalev Vows Orel Descent Module Replica for Drop Tests
SocialMar 30, 2026

Krikalev Vows Orel Descent Module Replica for Drop Tests

Since the beginning of the year, Roskosmos officials had made a couple of "proof of life" statements regarding the decade-late PTK Orel spacecraft. The latest being Sergei Krikalev's promise to complete a high-fidelity copy of the Descent Module, VA, for...

By Anatoly Zak
Automation Frees Reps to Focus on Real GTM
SocialMar 30, 2026

Automation Frees Reps to Focus on Real GTM

Before every episode in our VC series, @PaulGTM and I talk through what we're seeing across founders, funds, and go-to-market teams right now. Here’s what we covered - available in full here on X. - Why the core of great GTM hasn't...

By Max Altschuler
Transparency in AI Prompts Will End Writing Authenticity Debate
SocialMar 30, 2026

Transparency in AI Prompts Will End Writing Authenticity Debate

The great “is ai assisted writing real writing” debate will be over once OpenAI or Anthropic let people publish pieces with full reasoning and prompt attribution visible and available to prompt through The reasoning of the human and bot is...

By Mat Dryhurst
Support Both OpenClaw and Claude—Zero Setup Required
SocialMar 30, 2026

Support Both OpenClaw and Claude—Zero Setup Required

OpenClaw or Claude? While every marketing team is debating which one to pick, we decided to support both. No extra setup. Any model, ready to go. Use both without wasting anytime for setup

By ai_topia_
Never Store Passports; Avoid KYC Data Leaks
SocialMar 30, 2026

Never Store Passports; Avoid KYC Data Leaks

I'm not sending anyone my passport anymore My Portuguese lawyer wanted me to email her a copy of my passport for KYC I rejected and she was confused "I've never been hacked" 99% of people are not aware any account probably can and will...

By Pieter Levels
MOKiN 8‑in‑1 USB‑C Hub Streamlines All Connections
SocialMar 30, 2026

MOKiN 8‑in‑1 USB‑C Hub Streamlines All Connections

Running out of ports or want to simplify plugging your notebook into your accessories, from keyboard to monitor? Then you'll really appreciate the MOKiN 8-In-1 USB-C Hub. It even has some secret functions that are pretty slick, as I demonstrate:...

By Dave Taylor
Finance Should Be Frictionless, Not App‑driven
SocialMar 30, 2026

Finance Should Be Frictionless, Not App‑driven

The neobank era taught us one thing: People don't want to think about money Agentic finance takes that to its logical conclusion Zero cognitive load Zero manual intervention Zero friction We're not building better apps We're building systems that make apps obsolete

By Lex Sokolin
AI Workflow Automation Demands an Ecosystem, Not a Single Tool
SocialMar 30, 2026

AI Workflow Automation Demands an Ecosystem, Not a Single Tool

Working with AI to automate an organization’s workflow goes far beyond just using tools like Claude or Claude Code. Once you’re dealing with real scale — large datasets, multiple systems, and thousands (or millions) of users — it becomes a full...

By Omozara
Sycamore: Enterprise Agent OS by Sri's Stellar Team
SocialMar 30, 2026

Sycamore: Enterprise Agent OS by Sri's Stellar Team

Sri is building Sycamore: an agent OS for the enterprise. Great team and great product concept. Can't wait for the launch :)

By François Chollet
MCP Server Bridges AI Bots to Trusted Human Handoffs
SocialMar 30, 2026

MCP Server Bridges AI Bots to Trusted Human Handoffs

Your First CX MCP Server: The Missing Link Between AI Agents and Trusted Human Handoffs https://t.co/5vTnmKjkbw Why your #AI #chatbot still doesn’t know who your customers should talk to... and the simple standard that fixes it. #MCP #customerexperience #AIagent #agennticAI...

By Annette Franz
Renewables Linked to Lower Prices; Fossil & Nuclear Drive Up
SocialMar 30, 2026

Renewables Linked to Lower Prices; Fossil & Nuclear Drive Up

Of course this guy is spewing nonsense. More fossil fuels and nuclear both correlate with higher prices worldwide. Only wind-water-solar correlates with lower prices. https://t.co/288jwtUdqr

By Mark Z. Jacobson
AI Doc: Accessible Primer on AI’s Best and Worst Scenarios
SocialMar 30, 2026

AI Doc: Accessible Primer on AI’s Best and Worst Scenarios

The AI Doc is good - worth seeing if you're interested in the topic, an approachable primer and pretty decent at teasing out the best and especially the worst case scenarios. Nice companion to Artificial Gamer (2021) about OpenAI's...

By Chris Fralic
SNX Emerges as Barometer for Q2 IT Demand
SocialMar 30, 2026

SNX Emerges as Barometer for Q2 IT Demand

The Week Ahead In Technology for March 30th. $SNX is the key tech earnings read, best proxy for IT channel demand into Q2. @intel ships its first 18A-based vPro commercial platform this week. Core Ultra Series 3 with vPro, 125+ designs,...

By Patrick Moorhead
TeraFab's All‑In‑One Chip Dream Deemed Impossible
SocialMar 30, 2026

TeraFab's All‑In‑One Chip Dream Deemed Impossible

Last week @elonmusk unveiled #TeraFab — a chipmaker aiming to produce logic chips, HBM4 memory, and advanced packaging under one roof. But an exhaustive analysis by @tomshardware reveals so many factors working against TeraFab that it appears highly unrealistic. Indeed,...

By Jeremy Kaplan
Make Subject Lines Short, Specific, and Evocative
SocialMar 30, 2026

Make Subject Lines Short, Specific, and Evocative

Your cold email subject line is killing your open rates. Stop being vague. Stop being long. Stop being logical. Be evocative. Examples that work: • "Beat Tableau" • "Avoid expensive mishires" • "Stop losing great people" Short. Painful. Specific. That's what gets opened.

By Chris Orlob