
Fastest/cheapest inference for image generation? @FlyMy_AI gets added to @ArtificialAnlys /image as a provider, check out their speed vs cost running Qwen https://t.co/bIWEXQxuC1
SaaS companies that have an Ideal Customer Profile have a 68% higher win rate. Early-Stage Companies are more likely to hit true Product Market Fit once they do a proper Ideal Customer Profile exercise. Mid-Stage Companies are able to accelerate...
Would the #CDC's principal deputy director view it as a public health loss for the US if the country loses its #measles elimination status? "Not really," Dr. Ralph Abraham said at a press conference today. https://t.co/JXb3tlOrsu
In case you missed it, one apparent winner in today's bipartisan healthcare deal is the diagnostics firm Grail. $GRAL The company’s "multi-cancer early detection" test is already available, but in order to succeed it must leap multiple hurdles, including receiving...

Was doing a basic analysis of direct traffic as a % of all my traffic, holy smokes. its over 2x'ed since Q3 2024. That @randfish guy was on to something. https://t.co/p12mK9lV8b

One thing I learned by visiting @maticrobots today and seeing how they make floor cleaning robots (I have a video I might put up later this week) is that it's going to be very hard for a humanoid robot to...
our last 10 investments were: - 3 dev tools/infra - 3 vertical niche b2b - 2 deep tech - 1 consumer hardware - 1 general agent would be fun to look at some consumer AI this quarter

When you estimate the impact of your GEO work, you must determine what % of your tracked prompts are answered by training data vs web search. Why? Because Gemini 3 launched on Nov 2025, it's training cut off was Jan 2025. So...
You can't begin to agree on what # to hit unless you understand the market you're in. You can make a spreadsheet say anything. And of course your investors want double-digit growth this year. Will your market allow it? Is...
This AI startup scaled to $500M by betting on a market most tech startups overlook. Here’s how Listen Labs made it happen 👇 User research has always sat in an odd place. Everyone agrees it’s important. Very few teams run...
I'm lucky to have been through a few acquisitions in my career. You learn pretty quickly that the spreadsheets, decks, and integration plans matter, but they’re not what tell you if it’s going to work. People do. There’s a moment,...
me/air street 2014: begin investing in ai startups 2016: what wall st misses on nvidia 2017: why go long on ai 2021: the ai revolution is just starting 2024: ai is not the dot com bubble 2025: a monumental 12 months in ai 2026: lesgooooo ref:...

Really wild to see authoritative health publishers who have dominated in SEO for many years get hit so hard by this last core update, across various media networks Wondering if there is some cycle where content is now being answered by...

day #8 of the prompting game how many characters will it take you to get the AI to guess today's phrase? play at https://t.co/jmmguoWeQG https://t.co/jlL6jelBe9
I gave my Ops leader Lewis one prompt: forget faster. What's possible now that wasn't before? He said hold my Monster Energy and did the wildest thing. A lot of Ops people might have tried to keep this all to...
What sets @acquiredotcom apart? Our M&A advisory. We guide you through every step of your acquisition to maximize your exit. This M&A Insights Call showcases how Rainier Nanquil leads calls and gives guidance to founders. Learn more here: https://t.co/5hGUQheGfG https://t.co/6GklAPQyK5
before all these agents, i always had a python script that would traverse all the folders and files to concat into a single file so i could copy/paste easily into chatgpt

What a pleasure to have @adam_wills1 visiting us for this week to discuss notions of #quantumerrorcorrection. https://t.co/07pCKcT4pv
Financial relationships take time. Consumers kick the tires before committing fully, just like buying a used car. Digital players understand this patience. https://t.co/2BdOuNRPaG

Fed continues stonewalling all requests for transparency regarding its oversight of Synapse, arguing it is confidential supervisory information: https://t.co/VQcPyPqkNw
Blue Origin's own Laura Stiles, Dir of New Shepard Launch Operations, will get a chance to fly on New Shepard herself tomorrow bc one of the scheduled passengers (Andrew Yaffe) is ill and she'll take that seat.
I bootstrapped my first startup to $13m ARR in 26 months with only one sales rep doing OUTBOUND sales. The crazy part? Diana Ross did the same demo over 2,000 times using the same 10-slide deck. 👇 I just re-discovered...
You can build a ChatGPT app in 30 minutes that reaches 800 million users. This is the kind of distribution opportunity that comes around once or twice a decade—like the App Store in 2008 or SEO in the early 2000s....

After a decade of success, the modern data stack has entered consolidation. What comes next? The postmodern data stack is AI. The modern data stack created more than $100 billion in market cap with a simple promise : move the data via...
Being a MechE at Sunday isn’t about building flashy dancing robots. It’s about deep system thinking and the urgency to make robots genuinely useful for millions of homes.
January always gives me just enough quiet to think, right before the calendar fills up and momentum takes over. This year, I’ve been asking myself one simple question: What do I want to do differently in 2026? Not bigger. Not...

Using AI to prepare for a negotiation. For our free newsletter this week, we discuss AI shadow negotiators: invisible agents shaping human deals. @IrenaCronin and I write this newsletter every week. AI shadow negotiators are AI tools that quietly help people negotiate by...
Back in 2023, I gave a series of lectures at the Boulder Summer School on then-recent techniques we developed for error mitigation in NISQ devices, specifically how to combine Pauli twirling with probabilistic error cancellation to improve fidelity in noisy...
PAI is a super power. @DanielMiessler created features on top of Claude Code that increase its efficacy by 50%... and that's a lot based on how awesome Claude Code is. Incoming FREE workshop of PAI and other tools I'm using to...
📊 The 6 Dimensions of Data Science — a practical lens, not a buzzword map This framework is useful because it answers all the real questions leaders should ask: 1️⃣ Goals — Why Data Science? Insights, prediction, automation, optimization, and...
We're teaching everyone on the team to build AI workflows. Not to replace them. To unleash them. Most companies pick one of two paths: automate people out of jobs, or ignore AI and fall behind. We're doing neither. Customer experience....
What I see CEOs at struggling start-ups do: - Go dark - Hide - Lash out - Tweet about lots of things non-work - Invest time on tiny expenses - Argue internally What should do: - Be Present - Be Honest - Be the Rock - Be Realistic/Optimistic You just plain grow...
RFK Jr. is moving to remake a panel involved in that compensating people who are injured by vaccines. It could have big consequences. By @ChelseaCirruzzo. https://t.co/S98hMN6Vd0
Longevity biotech now targets root causes rather than single diseases. This is a paradigm shift in medicine
2025 will be remembered as the year AI stopped feeling “emerging” and started feeling like infrastructure. It quietly seeped into every layer of marketing—creative, media, analytics, and even how leaders frame strategy and risk. At the same time, the social...

Decoding the spatial dynamics of tumor and immune cell interactions in solid cancers https://t.co/AHgt77Ee2t https://t.co/1Xxkt45JlD
AI is messing with SaaS Conversion Benchmarks across the board. It’s time to reset expectations. We’re teaming up with Kyle Poyar @ Growth Unhinged and ChartMogul to build the 2026 SaaS Conversion Benchmarks. There’s too much anecdotal advice, and not...
A wave of AI startups is about to die - and most of them don't see it coming. not because their product is bad. because they built on someone else's data, and the landlords are changing the locks. For a...
The moments that change everything at work are rarely the big ones. They’re the passing comments, the tone in a reply, even the way a leader shows up in the in-between. These “insignificant” moments quietly shape trust, performance, and culture...
The most overlooked way to increase response? Give someone a choice. When you have a choice, you’re in control. And all humans crave control. We want to feel some agency. We don’t like to feel forced… Or backed into a...
Fintech is quietly back in the spotlight. It now captures 11% of global venture funding, second only to AI. Rounds are getting larger, and investors are focusing less on hype and more on business models that actually scale. The signal matters. As...

Are you ready to level up your bioinformatics skills? Let’s talk about repetition—a key concept that can save you hours in real-world data analysis. https://t.co/2Dtc9hz46e
Tomorrow I'm doing something I've never done before: Putting on a FREE, 90 Minute Sales Kickoff (SKO) for ANYONE that wants to dramatically improve their sales skills and mindset for 2026 - B2B, B2C, sales leaders, soloists, this is for...
Shared clinical decision making was devised to help patients & their doctors make choices when the answer isn't clear cut. People who devised the approach fear it's being hijacked to undermine decades of study supporting #vaccines, @EricBoodman writes. https://t.co/JMmaHTI7eg
Vaccine proponents worry that Kennedy will drive manufacturers from the US market by adding autism to the vaccine injury compensation program & unleashing a flood of litigation. The path to that change is through a committee he's currently "acip-ing." (clearing...
With AI, what’s more important: EQ (Emotional Quotient) or IQ (Intelligence Quotient)? #sponsored Gary Nugent , CEO of Informa TechTarget says brands who master the “right-brain” EQ elements of the buying journey will win in the age of AI. Full...

You’re analyzing 10x Genomics single-cell RNA-seq and notice lots of intronic reads. Wait—wasn’t this a 3′ UMI-based assay for mature mRNA? Let’s unpack why introns show up—and why they matter. 🧵 https://t.co/cDeb8dfLAS
Most "personal brand" problems are messaging or offer problems in disguise Sell something people want Explain it so they know why they should want it Creating unignorable content becomes much easier
For all you marketers trying to generate demand for AI products or features, this one's for you: It's all about helping you understand the top trends and pains in AI Adoption in the Enterprise in 2026 so you can align...
After working on 500+ Ideal Customer Profiles, I’ve identified the top 3 mistakes most Founders make– and they’re costly. In fact, many Founders inside my Unstoppable Go-To-Market program joined because their ICP wasn’t delivering growth or results. The three most...