The Connected Care Continuum: Enhancing Patient Care Across Settings
Healthcare providers are accelerating the shift toward a connected care continuum that spans hospitals, ambulatory clinics, post‑acute facilities and the home. Leaders at NewYork‑Presbyterian and PointClickCare stress that seamless, standardized data—delivered through integrated EHRs and modern APIs—must be actionable across all settings. Multi‑modal engagement tools such as portals, apps and remote‑monitoring platforms are essential to improve outcomes, cut costs, and enhance patient experience. Building this ecosystem relies on hybrid‑cloud infrastructure, HIPAA‑compliant security, and scalable interoperability standards like FHIR.
Sub-Q Bionics Closes $1.5M Pre-Seed
Sub‑Q Bionics announced the close of a $1.5 million pre‑seed round to fund its next‑generation lymphedema medical devices. The financing includes capital from the Mayo Clinic, Yeda – the Weizmann Institute’s tech transfer arm – and several private investors, with the...
Evolution of Pharmacotherapy in STEMI
The podcast examines how STEMI pharmacotherapy has transformed over the past 46 years, moving from routine fibrinolysis to routine primary PCI with potent antiplatelet regimens. It highlights the recent approval of zalunfiban, a fast‑acting glycoprotein IIb/IIIa inhibitor, for administration at first medical...
Pfizer, BioNTech to Pause COVID Vaccine Study Due to Low Enrollment
Pfizer and BioNTech announced the suspension of a FDA‑mandated post‑marketing study of their COVID‑19 vaccine due to insufficient participant enrollment. The trial, aimed at 25,500 adults aged 50‑64, was designed to assess safety, immune response, and efficacy against infection. Companies...
They Thought Their Hearing Was Gone Forever—Until Doctors Tried Something Radical
A 2025 Nature Medicine study showed that delivering a functional OTOF gene via an adeno‑associated virus dramatically improves hearing in patients with genetic deafness. Ten participants aged 1 to 24 across five Chinese hospitals experienced a reduction in hearing threshold...
Graphene 'Scaffold' Recruits Bone Cells and Helps the Body Regenerate Fractures
Researchers in Brazil have created a graphene‑based scaffold that repaired nearly 90% of bone fractures in rats within a month, outperforming existing biomaterials. The scaffold combines graphene with chitosan‑xanthan polymers derived from waste black liquor, a pulp‑and‑paper by‑product. Acting as...
Kailera Plots IPO to Fuel Obesity Pipeline
Kailera Therapeutics, after raising $1 billion across a $400 million Series A and $600 million Series B, is preparing an IPO to fund its obesity drug pipeline. Its lead candidate, ribupatide, has delivered up to 23.6% weight loss in Phase 3 injectable trials and 12.1% loss...
20/20 BioLabs Expands Longevity Test with Kidney Risk Tech
20/20 BioLabs announced an exclusive U.S. license with South Korea’s ROKIT Healthcare to embed its chronic kidney disease (CKD) prediction algorithm into the company’s OneTest for Longevity platform. The addition expands the test beyond inflammation biomarkers to provide early kidney...
Eli Lilly Opposes Push to Pass Trump's Drug Pricing Deals Into Law, CEO Says
Eli Lilly is publicly opposing the White House’s effort to turn its voluntary “most‑favored‑nation” (MFN) drug‑pricing agreements into law. The company, along with more than a dozen peers, signed MFN deals in 2025 to align U.S. prices with those in other...
Enlivex Clears Pivotal FDA Hurdle in Knee Osteoarthritis
Enlivex has secured FDA Investigational New Drug (IND) clearance to launch a global Phase 2b trial of its immunotherapy Allocetra for moderate‑to‑severe age‑related knee osteoarthritis. The study will be randomized, double‑blind, and placebo‑controlled, building on promising Phase 1/2a data from 134 patients....
CDC Tweaks Recommendations for ‘Rabbit Fever’
The U.S. Centers for Disease Control and Prevention has issued its first revision in nearly 25 years to the prevention and treatment guidelines for tularemia, a zoonotic disease also known as rabbit fever. The new recommendations reorganize guidance into distinct...
Study: Eye Microbiome Unchanged by Contact Lens Wear
A new study published in Microbiology Spectrum examined the ocular surface microbiome and tear proteome of 25 contact‑lens wearers and 23 non‑wearers. The researchers found no significant differences in bacterial composition or tear protein expression between the two groups. While...
FDA Open To More Data On Rare Disease Drug Ersodetug Despite Missed Phase 3 Endpoint
Rezolute announced that the FDA remains open to reviewing additional data from its Phase 3 trial of the rare‑disease hypoglycemia drug ersodetug, despite the study missing its primary efficacy endpoint. The agency’s willingness suggests the experimental therapy could still move toward...
Single Payer Isn’t The Only Alternative Healthcare System For The U.S.
After the Affordable Care Act subsidies expired, millions of Americans saw premiums surge, reviving concerns about the uninsured. Lawmakers are pushing single‑payer proposals such as Medicare for All, but a Pew 2025 survey shows only 35% of adults support a...
Newly Qualified Paramedics Told to Apply for Jobs Abroad Due to Hire Freeze
The Welsh Ambulance Service has imposed a hiring freeze on newly qualified paramedics, leaving around 70 graduates without NHS band‑5 positions. Despite receiving millions of pounds in bursary funding (≈$1.3 million USD), students are being advised to look for work in...
Test Maps Circadian Rhythm Via Hair Sample
Researchers at Charité have created a hair‑based diagnostic that reads the activity of 17 clock‑related genes to pinpoint an individual’s chronotype. In a study of over 4,000 volunteers, the test showed that lifestyle factors—especially employment—shift internal clocks more than genetics...
TCTMD’s Top 10 Most Popular Stories for March 2026
March 2026’s most‑read TCTMD stories were dominated by ACC conference data and new dyslipidemia guidelines emphasizing earlier, intensive LDL lowering and routine CAC and Lp(a) screening. Large trials showed that Impella mechanical circulatory support did not improve outcomes in anterior...
Researchers Unlock the Key to Axon Regeneration
Researchers at Icahn School of Medicine discovered that the aryl hydrocarbon receptor (AHR) acts as a molecular brake preventing axon regeneration after nerve injury. Genetic deletion or pharmacological inhibition of AHR in mouse models redirected neurons from a stress‑survival mode...
Report Shows How NIH Funding Ripples Through State, Local Economies Nationwide
United for Medical Research’s 2026 report finds NIH’s $36.5 billion FY ’25 budget produced a 250 % return, generating roughly $94 billion in economic activity and supporting over 390,000 jobs. The analysis maps the ripple effect of research dollars through equipment manufacturers, service...
Novo Cuts 400 Jobs in Indiana as Scholar Rock Refiles Drug Linked to the Factory
Novo Nordisk announced it will cut approximately 400 positions at its recently acquired Bloomington, Indiana manufacturing plant. The cuts follow FDA rejections of drug products from three contract companies that used the facility, citing manufacturing deficiencies. The issues stem from...
FDA Revises Recommendation on First Full Epcoritamab Dose in R/R DLBCL to Allow Outpatient Monitoring
The FDA has revised the label for epcoritamab (Epkinly) to permit outpatient monitoring of the first full 48‑mg dose in relapsed/refractory diffuse large B‑cell lymphoma (R/R DLBCL). The change follows interim EPCORE‑NHL‑6 data showing the dose can be safely administered...
Korsana Biosciences Announces Merger With Cyclerion Therapeutics, Concurrent $380 Million Private Financing
Korsana Biosciences announced a merger with Cyclerion Therapeutics, accompanied by a $380 million private placement. The financing round was led by Fairmount and Venrock Healthcare Capital, with participation from a slate of prominent venture and institutional investors. Cooley LLP represented the...
Paralympian Initiates Advocacy for Eye Care
Paralympian Amy Dixon has founded Vision Without Limits, a nonprofit that trains and employs eye‑care patient advocates. She created the Certified Ophthalmology Patient Advocate (COPA) program with Alchemy Vision, a six‑week online course that leads to certification and Medicare‑reimbursable services....
JAMA Study: AI Scribes Deliver Modest EHR Time Savings Across 5 Major Health Systems
Researchers published a JAMA study analyzing 8,581 ambulatory clinicians across five academic health systems, including 1,809 AI‑scribe adopters. AI scribes reduced total EHR time by 13.4 minutes and documentation time by 16 minutes per eight‑hour shift, yielding a modest 0.49‑visit...
‘Vaginal Estrogen as a Face Filler? I Think Not’: Experts Critique the New Skincare Trend
A viral TikTok trend is encouraging users to apply vaginal estrogen cream as a facial filler, citing its purported collagen‑boosting effects. Dermatology experts caution that the practice is off‑label, lacks robust clinical evidence, and may lead to systemic hormone absorption...
From Transparency to Action: Turning Price Data Into Lower Costs
The article argues that emerging price‑transparency data can dramatically lower U.S. health‑care costs if stakeholders use it to choose high‑value providers. It highlights stark price gaps—an MRI ranging from $125 to $2,565 and joint‑replacement fees varying 2.5‑fold across insurers. The...
Under the Magnifying Glass: A Wave of Drug Price Transparency
In late January and early February 2026, three federal initiatives – a Department of Labor proposed rule, the Consolidated Appropriations Act of 2026, and an FTC settlement with Express Scripts – introduced mandatory transparency reporting for pharmacy benefit managers (PBMs)....
Employers Can Now Save by Comparing Health Care Prices
Employers can now tap Hospital Price Transparency (HPT) and Transparency in Coverage (TiC) data to compare actual negotiated rates across carriers and facilities. A pilot by the Purchaser Business Group on Health (PBGH) and Milliman showed that Aetna’s rates for...
Teva Intensifies Biosimilar Competition with FDA Approval and Dual Filing Acceptance in US and Europe
Teva Pharmaceutical Industries received U.S. FDA approval for its denosumab‑adet biosimilar, covering all approved indications of Amgen’s Prolia, including osteoporosis and bone loss in cancer patients. The company also secured simultaneous acceptance of regulatory filings with the FDA and the...
Esketamine Nasal Spray Shows Rapid, Durable Effectiveness in Treatment-Resistant Depression
New real‑world evidence from the ECHO study confirms that esketamine nasal spray delivers rapid and durable symptom relief for adults with treatment‑resistant depression. In a European‑Israel cohort of 570 patients, average treatment lasted nine months, producing mean MADRS reductions of ‑10.3...
Amgen, Zai Lab Team up on DLL3; Janux Gets $35M Milestone Payment
Amgen and China‑based Zai Lab have announced a Phase 1b clinical study that combines Amgen’s T‑cell engager Imdelltra with Zai Lab’s experimental antibody‑drug conjugate zocilurtatug pelitecan, targeting the DLL3 protein in aggressive neuroendocrine cancers. The trial will evaluate safety and early...
Ambience Healthcare Launches Chart Chat for Nursing with Cleveland Clinic Pilot
Ambience Healthcare has introduced Chart Chat for Nursing, an EHR‑integrated conversational AI that lets inpatient nurses retrieve patient information with plain‑language queries. The tool debuted in a pilot with Cleveland Clinic, the first health system to test the technology after a...
A Paralyzed Musician Is Using a Brain Implant to Create Music
Research psychologist Galen Buckwalter, paralyzed since age 16, has six brain implants that translate his motor‑cortex activity into musical tones. The implants, each with 64 channels, provide 384 data streams that are decoded into pitch, allowing him to play a...
HNL Lab's Digital Pathology Platform Enables Faster Results and More
HNL Lab Medicine, part of Jefferson Health, digitized its anatomic pathology practice using six Leica GT450 scanners and Proscia’s Concentriq platform. The transition eliminated manual slide transport across a 14‑hospital network, enabling instant case sharing and remote work for pathologists....
Paragon Offshoot Korsana to Go Public in Reverse Merger for Alzheimer's Work
Paragon Therapeutics is spinning out its Alzheimer’s-focused unit, Korsana Biosciences, via a reverse merger that will list the company on a U.S. exchange. The deal, championed by Paragon co‑founder Jonathan Violin, merges Korsana with a publicly traded shell, providing immediate...
EHealth Gives Callers the Regal Treatment
eHealth partnered with Regal to launch Alice, an AI voice agent that handles Medicare Advantage, prescription drug and Medigap enrollment calls. The platform eliminated wait times, delivering zero‑second answer rates and a 27% higher purchase conversion than human screeners. After...
Rapid Response: How Boston Children’s Hospital Overcame the Stryker Cyberattack
Boston Children’s Hospital faced a massive wiper cyberattack that crippled Stryker’s Vocera communication platform, prompting an immediate, coordinated response. Within 30 minutes the hospital isolated the vendor network and began dismantling the compromised system. By evening, Epic Secure Chat was...
How a 20-Year Old Asthma Drug Is Boosting Food Allergy Research
A 20‑year‑old asthma medication, Xolair (omalizumab), is now accelerating food‑allergy research, especially for peanut sensitivities. Recent clinical trials combined the drug with oral immunotherapy, cutting severe reaction rates by roughly 70 percent. The FDA has recently cleared the first oral...
FDA Confirms Another Recall for Johnson & Johnson’s Impella Heart Pumps
The FDA has issued a Class I recall for Johnson & Johnson MedTech’s Impella purge cassettes, affecting over 33,000 devices. Leaking cassettes can cause low purge pressure, biomaterial ingress, pump stoppage, and potentially patient death. Four serious injuries have been linked to the...
Johns Hopkins Medicine and ATA Launch Interstate Telehealth Initiative
Johns Hopkins Medicine and the American Telemedicine Association have launched the LIFTT Initiative, a three‑year effort to push federal legislation that eases state licensure barriers for telehealth. The program seeks tailored federal pathways that complement, not replace, state oversight, aiming...
IO Biotech Will File for Bankruptcy After Failure of Cancer Vaccine in Key Trial
Danish biotech IO Biotech announced it will file for Chapter 11 bankruptcy after its lead cancer vaccine failed to demonstrate efficacy in a pivotal trial. The vaccine, designed to treat aggressive solid tumors, showed no statistically significant benefit, prompting the...
Partners Seek to Integrate Dental Care Into Nationwide HIE Infrastructure
CareQuest Innovation Partners and federally designated QHIN Kno2 have announced a partnership to embed dental data into the nation’s health‑information‑exchange (HIE) infrastructure. The collaboration targets bidirectional data flow between dental and medical providers, aiming for a production go‑live within six...
Link Found Between Antibiotics and Depression in Pregnancy
A large Japanese cohort of 94,490 pregnant women found a stepwise association between antibiotic use and psychological distress in early‑to‑mid pregnancy. Women who took antibiotics both before conception and after pregnancy recognition faced a 50% higher odds of severe distress...
Multiple CGM Sensors May Be Used with Automated Insulin Delivery
The FDA cleared Medtronic’s MiniMed 780G pump to operate with Abbott’s Instinct CGM sensor, expanding sensor options for automated insulin delivery. A real‑world study of 13,967 U.S. users showed time‑in‑range rose modestly from 75.1% with Guardian 4 to 77% with Instinct. Automated...
Elevance Sidesteps Medicare Advantage Sanctions for Now
Elevance Health avoided immediate Medicare Advantage sanctions after CMS granted a deadline extension to May 30 to correct years of faulty risk‑adjustment data reporting. The regulator had warned that non‑compliance would trigger enrollment bans and communication suspensions for its MA...
Lambert–Eaton Myasthenic Syndrome: Early Recognition, Diagnostic Precision, and Therapeutic Advances in Small Cell Lung Cancer
Lambert‑Eaton Myasthenic Syndrome (LEMS) is increasingly recognized as a prodromal marker for small‑cell lung cancer (SCLC), prompting clinicians to screen earlier. Recent advances in auto‑antibody assays and electrophysiological testing have sharpened diagnostic precision, allowing treatment to begin before overt tumor...
$235K Grant Boosts Lifesaving Gear for Pa. Ambulance Service
The Pennsylvania Department of Community and Economic Development awarded a $235,000 grant to the McCandless‑Franklin Park Ambulance Authority. The funds will purchase six LUCAS mechanical chest‑compression devices and a LIFEPAK 35 heart monitor‑defibrillator, which costs about $65,000. Each ambulance will receive...
Changemaker Awardee: HIMSS Involvement Fosters Career Growth
Cedric Truss, a Georgia State University student, joined HIMSS as a member and progressed to volunteer on multiple HIMSS committees and task forces. His hands‑on involvement gave him industry‑relevant skills, mentorship, and a robust professional network. Today, Truss actively encourages...
How 3D Medical Animations Transform Conference Presentations
Medical conferences are saturated with static slide decks that struggle to convey complex mechanisms, leading to audience fatigue and low retention. 3D medical animations replace static visuals with dynamic, motion‑driven storytelling, allowing presenters to illustrate molecular interactions, device usage, and...
STAT+: Insilico Medicine CEO on How Best to Use AI in Drug Development
Insilico Medicine, a veteran AI‑driven drug discovery firm, announced a partnership with Eli Lilly that includes a $115 million upfront payment and up to $2.75 billion in milestone‑based total consideration. The deal leverages Insilico’s generative‑AI platform to co‑develop novel therapeutics, primarily targeting metabolic...