Predicting Severe Diabetes Complications Using Administrative Claims Data in Maryland
A Maryland‑wide predictive model using Medicare fee‑for‑service claims and publicly available social‑determinant data generated risk scores for 346,614 beneficiaries, released on June 7 2024. The model retained 95 statistically significant factors out of 219 candidates and produced a mean score of 0.0124, indicating a 1.24% monthly chance of a severe diabetes complication. In the month following release, the top 10% of scores captured 56.9% of actual severe events, far surpassing the 37.5% captured by traditional Hierarchical Condition Category (HCC) scores. The model is now operational in Maryland’s primary‑care network, guiding proactive interventions.
Preventive Strategies to Lower Hand-Foot Syndrome Risk
Researchers published a meta‑analysis of 19 randomized trials showing that topical diclofenac gel significantly reduces the incidence of grade 2 or higher chemotherapy‑induced hand‑foot syndrome, especially in patients receiving capecitabine. The analysis also identified topical silymarin, pyridoxine 400 mg, and celecoxib as...
Somerset Indus Capital Partners Raises $288M in Fund III
Somerset Indus Capital Partners announced the closing of its third fund with $288 million in commitments, surpassing the $250 million target. The fund, backed by development finance institutions, global investors and family offices across Europe, the U.S. and Southeast Asia, will target...
Healthcare Recruiting Platform Lands $14.5M
Carefam, a conversational AI platform for healthcare staffing, emerged from stealth with a $14.5 million Series A led by Pitango HealthTech and backed by Emerge. The solution automates candidate outreach, interview scheduling, and credential verification, escalating only complex decisions to human HR...
COVID-19 Infection May Pose Greater Risks for Developing Kidney Disease Vs. Influenza
A new retrospective cohort study of over 3 million commercially insured U.S. adults found that COVID‑19 infection dramatically increases the risk of kidney complications compared with influenza. Adjusted hazard ratios show nearly double the risk of any kidney disease (HR 1.93), a...
Medicare Just Crossed $200 a Month. What It Means for Retirees
Medicare Part B premiums jumped to $202.90 a month in 2026, the first time they have cleared the $200 threshold. The Social Security cost‑of‑living adjustment added $56 to the average benefit, leaving retirees with a net gain of only about $38...
FDA Warns of Seizure Risk with some Parkinson’s Drugs
The FDA’s recent safety alert warns that high‑dose levodopa/carbidopa regimens can provoke seizures when patients develop vitamin B6 deficiency. Fourteen post‑marketing cases, including two fatalities, involved doses exceeding 1,000 mg daily and featured focal‑onset seizures that generalized. Vitamin B6 supplementation halted...
Kali Therapeutics Partners with Sanofi for KT501 in a ~$1.2B Deal
Kali Therapeutics has signed a license agreement with Sanofi granting the French giant exclusive worldwide rights to KT501, a next‑generation tri‑specific T‑cell engager aimed at B‑cell‑mediated autoimmune diseases. The deal provides Kali with $180 million in upfront and near‑term payments and...
Owner of Now-Closed Milwaukee Prenatal Care Coordination Company Sentenced to 60 Months’ Imprisonment for Healthcare Fraud Scheme
Lakia Jackson, 36, was sentenced to 60 months in federal prison for a Medicaid fraud scheme that siphoned $2.66 million intended for at‑risk pregnant women and young children in Wisconsin. She pleaded guilty to healthcare fraud and aggravated identity theft after...
Liqcreate Launches Dental Resin Designed to Eliminate Separating Agents in Orthodontic and Prosthetic Acrylic Workflows
Netherlands‑based Liqcreate has launched Separation Model, a dental photopolymer that embeds a non‑adhesive agent, removing the need for separate separating media in acrylic orthodontic and prosthetic workflows. The resin is compatible with most DLP, MSLA and laser 3‑D printers operating...
New Playbook for Private Healthcare Marketing in a Data-Driven Era
Private healthcare marketing is evolving from a standalone communications function into an integrated layer of the digital health stack, directly linked to EHRs, scheduling and telehealth platforms. This new model treats campaigns as dynamic demand‑orchestration tools that respond to real‑time...
Photon-Counting CT Better than Conventional CT in Lung Cancer
A prospective study of 200 adults compared low‑dose photon‑counting CT (PCCT) with conventional energy‑integrating detector CT for lung cancer imaging. PCCT reduced effective radiation dose by 66% (1.36 mSv vs. 4.04 mSv) and iodine load by 27%, while adverse reactions fell to...
The Future of Community-Based Healthcare Models
Community‑based healthcare is evolving from a peripheral add‑on to a primary delivery model, driven by decentralization, digital platforms, and value‑based economics. The approach embeds local clinics, health workers, and digital ecosystems to provide continuous, location‑specific care. Membership structures and managed...
Gut Health Research Is Changing Patient Care Models
Gut health research has moved from niche science to a core component of healthcare delivery. Recent FDA approval of Seres Therapeutics' Vowst and the rise of bioactive‑based microbiome products signal a shift toward industrialized, reproducible therapies. Companies across biotech, nutrition...
Henlius Receives NMPA IND Clearance for HLX18 (Biosimilar, Opdivo)
Henlius announced that China’s National Medical Products Administration (NMPA) has granted IND clearance for HLX18, a biosimilar of Opdivo (nivolumab), targeting resected solid tumours. The company also reported first‑patient dosing in Phase I trials for HLX17 (Keytruda biosimilar) and HLX13...
Xilio Therapeutics Announces Pipeline and Business Updates and Fourth Quarter and Full Year 2025 Financial Results
Xilio Therapeutics reported a strong cash position of $137.5 million, extending its runway to the end of 2027, and highlighted significant pipeline advances. The company plans to file an IND for its bispecific PD‑1/masked IL‑2 candidate XTX501 in mid‑2026 and start...
Mobile App Development in Telehealth Matters Now More Than Ever
Telehealth has evolved from a supplemental channel into the primary interface for care delivery, driven by mature infrastructure and patient expectations. Mobile app development—especially Android due to its worldwide device penetration—has become the core conduit for patient access, provider coordination,...
Man Wins $10M Jury Verdict After ED Physicians Order Wrong Imaging Exam
A Washington man was awarded a $10 million jury verdict after emergency‑department physicians ordered the wrong imaging study, delaying treatment of a spinal epidural abscess. The misstep resulted in a 17‑hour wait, during which his paralysis progressed and became permanent. The...
STAT+: Insmed Drug Benefits Patients with Rare, Bacterial Lung Disease, Study Shows
Insmed announced that a Phase 3 trial showed adding its inhaled antibiotic Arikayce to standard therapy significantly improved respiratory symptoms and boosted culture conversion rates in patients with newly diagnosed mycobacterium avium complex (MAC) lung infection. The study met its primary...
Staten Island Boasts Best Numbers Among Troubling NYC EMS Response Times
The Independent Budget Office report shows Staten Island achieved the fastest advanced life support (ALS) EMS response in New York City in 2024, with 82% of calls answered within ten minutes. Across all boroughs, response times have slipped over the...
Avalo Therapeutics Reports 2025 Financial Results and Recent Business Updates
Avalo Therapeutics announced its 2025 financial results, reporting $98.3 million in cash and short‑term investments that should fund operations into 2028. Research and development expenses jumped to $50.1 million, driven by the Phase 2 LOTUS trial of abdakibart (AVTX‑009) for hidradenitis suppurativa. The...
Daymark Health Builds Clinical Advisory Board
Daymark Health, a Philadelphia‑based cancer‑care platform, announced the creation of a Clinical Advisory Board to steer its value‑based, full‑risk care strategy. The board brings together leading oncologists, health‑policy experts, patient advocates and former government officials, including Dr. Ezekiel Emanuel and...
STAT+: Pfizer’s Lyme Vaccine Shows Efficacy, but Misses Key Statistical Hurdle
Pfizer and Valneva’s experimental Lyme vaccine cut the risk of infection by more than 70% in a late‑stage trial, offering a promising preventive tool for a disease that affects roughly 476,000 Americans annually. The study, however, missed its primary statistical...
STAT+: Apogee Therapeutics Data Show Long-Acting Eczema Drug Induced Relief with Less Frequent Injections
Apogee Therapeutics reported that its experimental long‑acting eczema biologic, zumilokibart, achieved sustained skin‑clearance in a mid‑stage trial. Seventy‑five percent of patients receiving the drug every three months and 85 % of those dosed every six months maintained an EASI‑75 response after...
IntraBio Reports the US FDA’s sNDA Submission of Aqneursa for Ataxia-Telangiectasia
IntraBio has filed a supplemental New Drug Application (sNDA) with the U.S. FDA seeking approval of Aqneursa (levacetylleucine) for Ataxia‑Telangiectasia (A‑T). The filing is supported by a Phase III trial that met its primary and key secondary endpoints and demonstrated a...
This Serial Entrepreneur Wants The FDA To Approve His AI Doctor
Serial entrepreneur Martin Varsavsky is launching Certuma, a startup aiming to create the first FDA‑approved AI doctor. The company raised $10 million in seed funding at a $60 million valuation and is targeting 25 low‑risk conditions such as UTIs and sore throats....
Examining Clinical, Public Perceptions of Hospice, Palliative Care
Recent research highlights three critical fronts in hospice and palliative care: a Community Hospice and Palliative Medicine (CHPM) fellowship at the University of Colorado is boosting mid‑career physicians' skills and confidence to address national workforce shortages; the Canadian PEACH program...
PointClickCare Launches Next-Gen EHR for Practice Groups
PointClickCare unveiled a next‑generation electronic health record tailored for practice groups, tightly integrated with its flagship post‑acute care platform used by over 30,000 organizations. The solution embeds AI‑driven Ambient Scribe and clinical risk insights directly into physician workflows, promising measurable...
Resmed’s Global Sleep Survey Reveals Sleep Is One of the Top Health Priorities, but Quality Rest Remains Out of Reach
Resmed’s sixth Global Sleep Survey of 30,000 respondents across 13 countries shows that 53% now rank sleep as the most important health behavior, ahead of diet and exercise. Yet more than half of participants report getting quality sleep only four...
“Mid-Life Health Crisis” Hits Millennials and Gen-Xers as Private Scans Soar
Britain’s mid‑life adults (30‑59) now account for 56% of all private diagnostic scans, a six‑fold increase since 2022, driven largely by chronic pain and preventive health concerns. With NHS waiting lists exceeding two million and delays over six weeks, private...
Ex-NFL Player Convicted in $328M Genetic Testing Fraud as Medicare Scrutiny Intensifies
A Dallas federal jury convicted former NFL player Keith J. Gray of orchestrating a $328 million Medicare fraud scheme that billed for unnecessary cardiovascular genetic tests. Gray, who owned Axis Professional Labs and Kingdom Health Laboratory, was found guilty of conspiracy,...
When Voters Worry About ‘Affordability,’ Many Point to Health Care
Voters who cite affordability as their top worry are overwhelmingly pointing to health‑care costs, according to recent polling. The trend has prompted Democrats to reframe their health‑care narrative around price rather than access, using the issue to energize their base....
Nominee for Ambassador to Hungary Co-Owns a Nursing Home That’s Suing the Trump Administration Over Medicare Payments
Benjamin Landa, a nursing‑home owner nominated by Donald Trump for U.S. ambassador to Hungary, is facing a lawsuit from his own facility, Pinnacle Multicare Nursing and Rehabilitation Center, which seeks to block a HHS audit that identified at least $31.2 million...
Risk, Readiness and Resilience
Life‑sciences firms are confronting compressed validation timelines, tighter regulatory oversight and fragile supply chains, prompting a shift from cost‑driven to confidence‑driven site selection. Middlesex County, New Jersey, offers that confidence through a highly educated talent pool, continuous university‑backed research, and deep...
Even With Dental Insurance, You Still Could Face a Large Bill
Even with dental insurance, many Americans still face sizable out‑of‑pocket bills. The article follows 65‑year‑old Russell Anthony, who expects to spend about $2,000 on dental care despite having coverage, illustrating the common "100/80/50" rule and annual benefit caps of $1,000‑$2,000....
ProPublica Adds Ownership Search to Nursing Home Inspect Database
ProPublica has upgraded its Nursing Home Inspect database with a searchable owner, manager, and officer function, letting users trace ownership across more than 14,000 facilities. The new tool reveals that a single individual can be linked to over 100 nursing...
HUTCHMED Initiates P-III Trial of HMPL-760 + R-GemOx for R/R Diffuse Large B-Cell Lymphoma in China
HUTCHMED has launched a Phase III trial of HMPL‑760 combined with R‑GemOx in relapsed/refractory diffuse large B‑cell lymphoma (DLBCL) patients in China, dosing the first patient on March 20, 2026. The study will enroll approximately 240 patients who have failed first‑line therapy and...
A Dynamic Yolk–Shell P–N Heterojunction With Coupled Shear Stress‐Triggered Tribo‐/Piezoelectric Effect for Catalytic Thrombolysis
Researchers introduced a yolk–shell BFO@tBT‑C nanoparticle that exploits shear stress at clot sites to trigger coupled tribo‑ and piezoelectric effects, generating reactive oxygen species for thrombolysis. The dynamic p–n heterojunction yields potentials 3.6‑ and 2.1‑fold higher than isolated triboelectric or...
Dizal Reports the P-III (WU-KONG28) Trial Results on Zegfrovy (Sunvozertinib) in EGFRm NSCLC
Dizal announced topline results from its Phase 3 WU‑KONG28 trial, comparing oral once‑daily Zegfrovy (sunvozertinib) to platinum‑based chemotherapy as first‑line treatment for advanced NSCLC with EGFR exon 20 insertion mutations. The study met its primary endpoint, demonstrating a statistically significant improvement in...
US Weight Loss Drugmakers Slash Prices in Fight to Win Customers
U.S. weight‑loss drugmakers are slashing GLP‑1 prices to win cash‑pay customers as insurers balk at coverage. Eli Lilly reduced Zepbound’s monthly cost by $50‑$100, bringing it to $299, while Wegovy now sells for $149 a month, far below its $1,600 launch...
Which Critically Ill Patients Are More Susceptible to the Adverse Effects Associated with Feeding Intolerance? A Secondary Analysis of a...
A secondary analysis of the multicenter NEED trial found that feeding intolerance (FI) in critically ill patients receiving early enteral nutrition was linked to higher 28‑day mortality after multivariable adjustment (adjusted OR 1.37). FI also resulted in longer ICU stays, fewer...
Professional Perspectives on PN Among Registered Dietitians in Saudi Arabia: A Mixed-Methods Assessment
The study surveyed 88 registered dietitians in Saudi Arabia to assess attitudes and readiness for personalized nutrition (PN) and multi‑omics technologies. Adoption of PN technologies was low at 16%, with work experience showing a modest positive correlation to perceived usefulness,...
Clinical Implications of Malnutrition in Huntington's Disease Progression: Evidence From a Chinese Cohort and Mendelian Randomization
Researchers evaluated nutritional status in 113 Chinese Huntington’s disease patients using CONUT, GNRI, and PNI scores and compared them with matched healthy controls. Malnutrition was markedly more common in HD, especially by CONUT (34.5% vs 13.3%) and GNRI (8% vs...
Associations of Inflammation-Related Nutritional and Metabolic Status Indices CAR and CTI with 90-Day Unfavorable Functional Outcomes in Patients with Acute...
A Korean stroke registry of 1,484 acute ischemic stroke patients examined whether the C‑reactive protein‑to‑albumin ratio (CAR) and the CRP‑triglyceride‑glucose index (CTI) predict 90‑day functional outcomes. After multivariable adjustment, higher CAR (OR 1.25) and higher CTI (OR 1.38) were independently associated with...
Powering the Next Wave of Cell Therapy: From iPSC-Derived Cells to In Vivo Reprogramming
Induced pluripotent stem cells (iPSCs) are being engineered into diverse therapeutic cell types, while in vivo reprogramming aims to convert resident cells directly within patients, eliminating traditional cell‑manufacturing steps. Both strategies depend on precise recombinant growth factors, cytokines, extracellular matrix proteins...
Reinforced Biotubes: Readily Available Regenerative Vascular Grafts
Researchers Cheng, Zhi and Midgley have unveiled reinforced biotubes—bioengineered vascular grafts that combine living cells with nanofibrous reinforcement—to address durability and availability limits of current grafts. The tubes are fabricated in bioreactors, seeded with smooth‑muscle and endothelial progenitor cells, and...
Gene Therapies for Hearing Loss Strike an Encouraging Note in Embattled Modality
Gene‑therapy candidates for hereditary hearing loss are gaining traction as safety concerns ease with localized delivery. Regeneron’s DB‑OTO and Eli Lilly’s AK‑OTOF have each demonstrated clinically meaningful hearing improvements in early‑stage trials, positioning them as frontrunners for the first approved deafness...
Bayada Nonprofit Executive Director On The At-Home Care Medicaid Squeeze, Industry Consolidation
Sue Chapman Moss, Bayada’s senior vice president of payer strategy and new executive director of Hearts for Home Care, warned that state Medicaid reimbursement is tightening after the One Big Beautiful Bill, pressuring home‑based providers with lower rates and reduced...
Are There Disadvantages of Knee Replacement Surgery?
Knee replacement remains one of the most common orthopaedic procedures, with roughly 800,000 surgeries performed annually in the United States. Advances such as cementless implants, robotics and refined soft‑tissue balancing have improved precision and reduced recovery time, making about half...