Allogeneic Stem Cells Safely Boost Function in Frail Adults
Allogeneic Mesenchymal Stem Cells Ameliorate Aging Frailty: A Phase II Randomized, Double-Blind, Placebo-Controlled Clinical Trial “Treated groups had remarkable improvements in physical performance measures and inflammatory biomarkers, both of which characterize the frailty syndrome. Given the excellent safety and efficacy profiles demonstrated in this study, larger clinical trials are warranted to establish the efficacy of hMSCs in this multisystem disorder.” 🔑 Key findings “ The CRATUS trial is a randomized, double-blind, placebo-controlled evaluation of allo-hMCSs to treat the signs and symptoms of frailty. The results support the safety and feasibility of administering allo-hMSCs in this population. With regard to efficacy, there was a preferential effect towards improvement of functional capacity and patient reported outcome measures in patients receiving lower dose MSCs, although immunologic bioactivity was evident with both doses. Together, these findings suggest that allo-hMSCs may be an effective biological modifier of aging frailty, and support ongoing investigation of allo-hMSCs alone or as an adjunct to current physical training strategies for aging frailty.” https://t.co/BKh5TaWT1J
Poste Italiane Bids €10.8bn for Telecom Italia
The re-Post Officication of telecoms was not something I expected to read this morning: Poste Italiane launches €10.8bn bid for Telecom Italia via @FT https://t.co/gR3vmnrlkX
Airline Puts Woman, Child in Cockpit to Dodge Compensation
Woman And Child Flew Six Hours In Cockpit Jumpseats — Airline Avoided Paying Overbooking Compensation - View from the Wing https://t.co/22hFCb7EkB
Space Policy Week Brims with Unmissable Highlights
Impossible to choose just one "pick of the week." SO much going on... What’s Happening in Space Policy March 22-28, 2026 https://t.co/PBNQ87f5RZ
California Batteries Power Significant Evening Electricity Supply
Batteries (purple) in CA already a significant part of the electricity supply in the evenings. And even a little in the early morning. https://t.co/zBs7Yb51Qy https://t.co/h8vRfr4sXx
Early Helium Alerts Now Gaining Wider Attention
I told you about Helium since day one of the Hormuz crisis… now people are catching up to it !
Spot Consistent Creators Who Post Daily, Regardless of Size
Dear Algo, send me the creators who are showing up every single day even when the numbers are small.
Australian-Backed Rooftop Solar Powers Remote Samoa
Australia-backed rooftop solar to power remote Samoan communities #energysky -- via pv magazine global: https://t.co/tbaM3Iwf0s https://t.co/GFAcZQNY94
Tesla Secretly Uses LiDAR for Vision Training, Not Production
This is getting dunked somewhat unfairly. Tesla is using LiDAR to get training data to improve their vision-only systems. That should raise some eyebrows - LiDAR is clearly valuable in ways Elon denies. But it's not the same as using...
AI‑first Workflow Builds $10k/Mo E‑com Brand
How To Build A $10,000/mo AI Ecom Brand in 2026 (Full Guide) WATCH HERE 👉 https://t.co/VuFsAF4ETI The "Old Way" of E-commerce is dead. In 2026, if your store looks like "dropshipping," it won't convert. I’m showing you the exact AI-first workflow...
Whiteboard Tactics Unlock NHS Negotiation Success
The Whiteboard Windfall: A Lesson in NHS Negotiations by @Timothy_Hughes https://t.co/2JqnBxsbKP @DLAIgnite #SocialSelling #DigitalSelling #Sales #SalesTips #SalesLeader #Salesforce #SalesEnablement #RevOps #Leadership #Marketing #SalesNegotiation https://t.co/QfAUP3Lf1B
Try Build‑to‑Rent Before Dismissing It
Don’t knock it until you’ve tried it. Follow @chasecalhoun.realestate for more on build-to-rent and real estate investing. #realestate #investmentproperty #buildtorent
Considering a Used F250 Purchase This Summer
I’ve been in the market for a used F250. Thinking this summer might be a good opportunity. https://t.co/hlsi7GwL5b
Why the “Never Take
This is why I don't like the "never take anything off the table" chestnut. It was dumb with Hillary said it about nuclear weapons in Afghanistan; it's dumb now. (And no, I don't think he means it.)
Polymarket Predicts 28% Chance Hormuz Reopens by April
Polymarket, a large prediction market, shows only a 28% chance that the Strait of Hormuz will open for normal traffic by the end of April. TRUMP & NETANYAHU’S WAR ON IRAN = MASSIVE COSTS. https://t.co/slk6gIZTUJ
Specify the Target; Attacking a Nuclear Plant Is Illegal
"Guess again" is an interesting answer when you could just state the target you have in mind and then affirm that targeting an operational nuclear power plant would be a crime.
Iranians May Soon Target Lucrative Data Center Assets
I wondered when the Iranians would get around to targeting data centers. They're pretty juicy, as potential targets go.
Weak Stock Prices Fueled 2015, 2018 Buybacks, M&A
BofA: Weaker stock prices were behind the jump in share buybacks and M&A spending in 2015 and 2018. https://t.co/zOxaox8YSB
Iran's Petrodollar Attack Meets 10 M
"Iran is going after the petrodollar system" Brother, they've already shut in 10 million barrels per day of Gulf crude oil production capacity. What petro?
Quebec-Queens Hydropower Line Could Light One Million NYC Homes
"Hydropower Line From Quebec to Queens Could Power a Million N.Y.C. Homes" https://t.co/CEfzSRT1cG "Its construction included the underwater installation of more than two million feet of cable imported from Sweden" https://t.co/xqTcpfviM5
Russia Repurposes S‑
The use of RM-48U is a growing issue, supplementing existing SRBMs. Russia is dedicating certain S-400 air defense units to this strike role. https://t.co/RPvaVKxyaE
Airlines' Abandoned Fuel Hedges Signal Rising Ticket Prices
Oh no! US airlines are no longer hedged against oil price shocks. Now we will all be paying in higher fares. Just like PJM states who didn't hedge against the recent increase. And California in 2000-2001. Hindsight is 20-20 but...
Houston TSA Delays Reach Two‑and‑half Hours
Two and a half hour wait for TSA in Houston? Is it too obvious to say? Houston, we have a problem. https://t.co/rUJvgxQ9c1
Tomorrow: CNBC Morning Call on AI Stock Winners
Look forward to being on the new show launch of @CNBCMorningCall tomorrow at 5:45 am with @MorganLBrennan to discuss tech stocks and navigating this white knuckle moment for AI winners @CNBC @CNBCtech 🏆🐂📺🍿☕️
Lifestyle Program Slows Aging and Boosts Function in Frail Seniors
A Multidomain Lifestyle Intervention Is Associated With Improved Functional Trajectories and Favorable Changes in Epigenetic Aging Markers in Frail Older Adults: A Randomized Controlled Trial https://t.co/8Ex1caVyLp
Short‑lived Traffic Managers Fuel Impending Carrier Revenge
The issue at many major shippers is that the tenure of the traffic manager is less than two years. They've never seen a carrier's market. They don't know what its like when truckers have the power. Carrier's Revenge is...
US Sanctions Expose Risk of Single‑government Payment Systems
Trump sanctioned French judge Guillou over the Netanyahu arrest warrant → Visa and Mastercard had to cut him off because they're American companies bound by US law. A European judge, debanked in Europe, by US sanctions. Maybe we actually need payment alternatives...
New Home Sales Yet to Slip Below 2022 Lows
If new homes can fall below the 2022 lows in sales for at least 5-7 months, that would do it, but their purchase application data hasn't shown that yet. https://t.co/Jv2eyLip1u
Freight Market Flipping: Unprecedented Capacity Churn Sparks Demand
The SONAR team has been telling shipper and broker clients for months that every capacity signal was warning that the freight market was flipping and it wasn't just holiday peaks or weather. Unprecedented capacity churn with early green shoots in...
Hackathon Targets Neural Repair, AI Surgery, Cryo Innovations
DEFEATING ENTROPY hackathon at @fiftyyears London HQ. Focus areas: Biomaterials for neural repair Engineered neural cells Tissue replacement AI for surgical robotics Advanced cryo methods Biostasis https://t.co/gMDDoo6Io4
Only 7% of Americans Back Trump's Iran Troop Threat
Only 7% of Americans support Trump's threat to send US ground troops into Iran. AMERICAN SUPPORT FOR THE US-ISRAELI WAR AGAINST IRAN = VIRTUALLY NONEXISTENT. https://t.co/5SDVzUht3L
Industry Often Chooses Worse Practices Over Real Improvements
I've said this a few times now, but I'll keep saying it: it's also a mistake to assume that the industry in general cares whether something is a clear improvement. We have a long history of adopting new practices that...
Nanostructured Silicon May Surpass Shockley‑Queisser Solar Limit
Nanostructured silicon could push solar cells beyond Shockley–Queisser limit #energysky -- via pv magazine global: https://t.co/3gDJBe2BOt https://t.co/QQOp2n12dC
Escalation Risks Iran Mining Hormuz, Deepening Humanitarian Crisis
At what point does this escalation by Trump-Netanyahu actually prompt Iran to mine the Straight of Hormuz... with these ships on it?! Then this humanitarian crisis goes from lock-down to existential pretty quickly.
How to Protect Yourself After Companies House Breach
I’m worried about the Companies House data breach, what can I do? - The Times and The Sunday Times https://t.co/Ob5FvbS46f
Trump Uses Iran Grid Threat to Bait NATO
Is Trump’s threat to destroy Iran's power grid a gambit to pull NATO and Europe into the Strait of Hormuz? It’s a smart leverage point, given that Europe and Turkey are the ones most vulnerable to a new refugee crisis.
Inside the Future of Artist Royalties and AI Music
went deep on artist royalties, AI music, @spotifyforartists features, and the streaming business with @andrew.southworth & @mypoint4cents. covered a lot of complex and important topics in the hour (but hopefully didn't make the expression in the thumbnail for more than...
Dollar-Oil Surge Cripples Emerging Markets, Unmodeled Squeeze
DXY up 3% in a month on safe-haven demand. Oil up 50%. Dollar up AND oil up simultaneously. Emerging markets are getting crushed from both sides. This is the squeeze nobody is modeling. https://t.co/xogAtPGq0m
Panic Undermines All Oil Market Stabilization Attempts
Ever wondered what’s really behind the complete failure of all oil-market stabilization efforts? elow is one source of the panic that nullify the impact on any mitigation that I talk about here: https://t.co/P9npOEgoFO
Long‑term Supply Contracts Now Standard Through 2028
Yep, and through 2028 now at least. Everyone in the supply chain we talk to is noting how LTA's extend with every customer conversation. Now multi-year is the standard--which is something if you know historical memory supplier agreements.
Waiving Restrictions Lets Putin Sell Oil at 2022‑level Prices
By what? Giving waver to Putin to sell his oil freely at prices we have not see since 2022? 😉
War Triggers Soaring Commodity Prices, Gas up 85%
Price increases since the start of the Iran war... European Natural Gas: +85% Heating Oil: +80% Brent Crude Oil: +54% Urea: +48% WTI Crude Oil: +46% Gasoline: +44% Diesel: +42% Sulfur: +25% Coal: +24% Fertilizer: +23% Palm Oil: +13% US Natural Gas: +8% Iron Ore: +7% Rice: +7%
Grid Collapse Sparks Propane, Then Water Wars Amid Unprecedented Heat
What happens when the grid fails? Prediction: propane wars will precede water wars... you'll want to keep those emergency generators for AC running until you die of thirst.
RSAC 2026 Promises Exciting Cyber Innovations and Announcements
Inbound for RSAC. Going to be an interesting week of cyber products, innovations and announcements. My initial thoughts: https://t.co/l36K8t0RcX #cio #ciso #rsac2026 #rsac https://t.co/BCThYsakyZ
Japan Harvests Power From Footsteps with Piezo Tiles
#WhatsNext? Electricity from walking? Japan is using piezoelectric floor tiles to generate clean electricity one step at a time. (Interesting World) #Alternate #Energy #JVGpost https://t.co/yp7Ce1RXGg
Residents Oppose New Homes Near Tube, Question Double Standards
A community outside of London, served by the Tube with a train every 7 minutes, opposing 150 more homes directly next to the station begs the question: would they have supported their home being built under the same logic? (Duncan...
AI Lab Boosts Content Speed and Research Depth
Tyler Bloom needed his content to be sharper, faster, and more research-backed—without hiring a bigger team. The AI Business Lab® Mastermind showed him how. His newsletter is now developed 1–2x faster with deeper research and greater impact. The Slack community and...
Higher Thymic Health Scores Predict Longer Healthspan
Your Thymus and Your Healthspan https://t.co/ENhIn2A2l3 High vs Low Thymic Health Scores and Outcomes https://t.co/oOz9sOK8RV
Iranian Regime Chaos Spreads as Security Forces Crumble
"With thousands of regime members killed—from top leaders to street-level grunts—Iranians are reporting that a sense of disorder is starting to take hold. Security forces are under stress and on the run as they threaten protesters to stay off the...
2026 Mazda CX-50 Hybrid Delivers Luxurious Compact SUV Experience
The 2026 Mazda CX-50 Hybrid AWD Premium Plus offers a refined, surprisingly luxurious drive experience. It's a solid compact SUV that I drove for a week. Here are my thoughts and commentary: https://t.co/ezHTzu1mqe #mazda #suv #cars #auto @mazdausa https://t.co/Qbs8FdjBGy