Great City Design Makes Walking Effortless
25,208 steps today in Montreal. I didn’t plan to walk that much. The city just made it easy to keep going. That’s the thing about good environments — they do the work for you. https://t.co/yTw0fDi8HO
Living in Memory Blinds You to the Present
When you live within your memory, you cannot see what is right in front of you. #SadhguruQuotes https://t.co/AduvGSMRMR
The Conversation Demands Evidence Links; Awaiting Book Tour Dates
The Conversation (TB Times picked it up through syndication) has very strict guidelines for what they will publish. Links to evidence are required, and they're all in the article. This book tour sounds cool though; hope someone sends me the...
Excuses Kill Success; Vision and Preparation Drive Achievement
"Ninety-nine percent of the failures come from people who have the habit of making excuses. There is no short cut to achievement. Life requires thorough preparation. Where there is no vision. There is no hope." -George Washington Carver
Genetic Bridge Links Ageing Theory to Lifespan Interventions
Dynamics of genetic and somatic trade-offs in ageing and mortality “These findings provide a genetic bridge between evolutionary theories of ageing and molecular mechanisms that can guide interventions to extend healthy lifespan.” https://t.co/HFGnELAIqH https://t.co/gAlE7D4OCh
Epidemiology Insights: Tackling Pandemic Threats with Prof Rimoin
Great to host my extraordinary colleague/friend Prof Anne Rimoin @arimoin @UCLAFSPH UCLA Fielding School of Public Health here at @TXMedCenter @BCM_TropMed @TexasChildrens discussing her important work tomorrow on epidemiological approaches to pandemic threats and public health https://t.co/mKRffWimMv
Crowdfunded Rapamycin‑Exercise Trial Shows Promising Aging Data
Five years ago, @BradStanfieldMD reached out with an idea: a crowdfunded clinical trial testing rapamycin combined with exercise in older adults. The results are now published — and Brad and I just sat down for a full 42-minute breakdown...
Juvenile Reflects on New Orleans, Aging Gracefully in Rap
This @ocksportello piece is nominally an interview with Juvenile, but it's also a rumination on the wonders of New Orleans, aging gracefully in rap, and not taking anything for granted in life. It's also a fantastic interview with Juvenile. https://t.co/8aoxjoFcBN @juviethegreat
Reviving Mayagüez's Heritage: Charm Preserved in Renovation
Always feels good when someone renovates an old derelict building and keeps the original charm. This time in Mayaguez, PR https://t.co/tmszTPQhfW
Constant Self‑tracking Feels Exhausting; I Need a Break
idk if I can keep this up you guys. I just got one more to do: a five min warm eye compress before bed. I do endless things every day. From the moment I wake up to bedtime, and even...
Our Brain's Built‑in Lies Boost Motivation
“Your brain evolved to lie to you about your chances, your control, and your capabilities…” Sounds very very similar to my recent article on “useful falsehoods”
Guard Against Arrogance When Success Arrives
All of us need to be on guard against arrogance, which knocks at the door whenever you are successful. —Steve Jobs https://t.co/ySumBVrZQh
True Success Is Working Hard Despite Fatigue
Those times when you get up early and you work hard. Those times when you don’t feel like working, you are too tired, you don’t want to push yourself, but you do it anyway; that is actually the dream. —Kobe Bryant...
Scrotal Sun Myths Debunked: UV Boosts Testosterone Generally
Sorry to be the bearer of bad news but this is bullshit. The 1939 paper referenced is a study conducted on institutionalized men with documented depression, measuring a urinary testosterone byproduct, not serum levels, and without a control group. There...
Increase Training Volume for Sustainable Performance Gains
Your training volume sets your performance limit. Sure you can do intervals for a couple of months to get a temporary boost. But, for lasting, sustained improvement, the only way forward is to figure out how you can do (and absorb) more.
Defend Creative Courage: Silencing Haters, Embracing Challenge
How to neutralize haters – e.e. cummings, creative courage, and the importance of protecting the artist's right to challenge the status quo https://t.co/TaDLKht5KZ
Lab Culture: Marriage Okay, Pregnancy Discouraged During PhD
One of my wife's best friends started a bench science PhD at an ivy league When she got engaged after her first year, her PI took her aside and said, "Getting married while working in my lab is a perfect time...
Sleep Loss Damages Brain, Fuels Anxiety and Depression
Hard truth: Sleep deprivation isn't just making you tired—it's causing brain damage, anxiety, and depression that doctors are missing. Your body doesn't adapt to sleep loss. It breaks. Slowly, then all at once. Stop treating sleep like it's optional in 2026. Comment SLEEPFIX...
Fundamentals Beat Supplements for Athletic Performance
Dear student athletes protein powders and creatine gummies will not make up for your lack of consistency in these crucial controllable habits 👇: ✔️ 7-9 hours of sleep ✔️ 3-4 balanced meals daily ✔️ Eating at least 3-4 fruits and veggies ✔️ Carbs and...
44‑Year‑Old PED‑Free Squats 625 Lb, Eyes Nationals
Squatting 625 for 2 at 44 years old PED free 4 weeks ‘til nationals. BRING IT https://t.co/DxBsaYt6kP
Columnless Midiprep: Pool Minipreps, Elute at Quarter Volume
Nice. Good midiprep. Gonna use this for some gene gun optimizations. All columnless, simply combining a few minipreps and eluting in ¼th volume. https://t.co/0unMuxJTIc
AI Uncovered Missed ADHD Diagnosis at Age 70
I was diagnosed with adult ADHD last year. At 70. Decades of excellent therapists had missed it. Not because they weren't skilled—because each one only saw a slice of me. AI saw the whole picture. Then I brought it to my doctors. https://t.co/V6hjnDkJRX
Beyoncé's Act I/II
beyonce act i/act ii has led to a lot of artists and fans saying interminably boring and stupid-sounding things about what genre their next album is going to be or should be
Rehydrate, Refuel, and Supplement for Optimal Recovery
🧽Your muscles are like a sponge once a training session or game is finished 💪 Immediately: 💦 Rehydrate with 16-20 oz H20 Within 30-60 min ⛽️Repair + rebuild with 25-40g of protein + 30-60g of carbs •Chocolate milk + banana + HB eggs •Turkey sandwich +...
Seeing Earth as a Pixel to Hunt Life
🌎 For Earth Day, consider our pale blue dot as a single pixel 🔵 like Cassini saw looking back at Earth from Saturn. What might we glean from a single...
Fear Setting Turns Worst-Case Thoughts
Business is hard. Stressful. Difficult. But always dwelling and thinking about the worst thing that can possibly happen will cripple you and slow you down. Instead, I prefer to do an exercise called “fear setting” where you write down all...
Kids Take on MLB The Show 26, Yankees Assigned
Playing MLB The Show 26 with my sons 👌 11 year old drew the short straw so he has to be the Yankees https://t.co/rqTcrS5rK4
Find Powerful Why's or Rethink Your Goals
If you aren’t making progress, you need to spend more time creating an intense, emotional set of reasons driving you toward your goals. Or, you need to be honest with yourself if you don’t have strong enough reasons for that goal,...
Shingles Vaccine Cuts Dementia Risk by Half.
Have you had your shingles shot? A major 2026 study of over 300,000 people age 65 and older found that the shingles vaccine reduces the risk of dementia by up to 50%. Remarkably, men, women, and folks across age and ethnic...
Age‑and Sex‑Specific Genes Shape Lifespan Trade‑offs
Delighted to have contributed to this new study @Nature on the genetics of ageing and mortality 🧬 Using a large mouse cohort, we uncover age- and sex-specific genetic effects, including trade-offs where variants are beneficial early in life but detrimental later.
Effortless Idea Capture Unlocks Productivity Success
Most productivity systems don’t fail at execution… they fail at the very first step: Collection. If capturing ideas feels like a chore, your system is already leaking energy. In this video, I break down how to make collection effortless, friction-free, and...
Artemis II Validates Laser Links as Orbital Compute Backbone
Artemis II wasn’t just a deep space mission, it proved that laser communications will be the backbone of compute in orbit, with transceivers from @ObservableSpace Observable will move terabits between Earth and space, enabling datacenters, and more, in space. Observable...
Opportunities Constantly Knock—Learn to Hear Them
Opportunity doesn’t knock just once. It knocks all the time; though you may not recognize the sound. Pay attention. Opportunities are everywhere and often overlooked. #businessbuilding #growthmindset #virtualcoaching #frippvt
Sell Smarts, Not Software: Reframe to Close Deals
In 2012 I was a college dropout SDR making $36K a year with a kid on the way. I had no business being in tech sales. But I also had no backup plan, which turned out to be the only competitive advantage...
Checking In Saves Lives, Even Without Reciprocity
I have homies that I will call and check on if I don’t hear from them in a while. They never return the favor. Ever 😮💨. I don’t take it personally. I still call those boys and make sure that...
Fenebrutinib Shows Promise, Yet Safety Concerns Loom
Relevant to $TGTX was the Roche $RHHBY fenebrutinib trial results recently announced. Excellent efficacy, but two cases of Hy's Law. Both resolved, but a patient might not be so lucky next time. Hard for me to see this gaining widespread...
Reverse Osmosis Cuts Microplastics, Add Mineral Drops
One of my first recommendations for people wanting to reduce their microplastic exposure at home is a reverse osmosis filter. They remove 99%+ of microplastic particles and other contaminants. But they also remove trace minerals, so adding them back with mineral...
Ticket Sales Signal Michael's Big Weekend Earnings
Looking at tickets sales for this weekend… I think #Michael is going to make a LOT of money https://t.co/yqAM2Kt0iC
Intense Exercise Boosts Belief, Cuts Depression and Anxiety
Physical Activity and Mental Health of Employed Adults: Mediation and Moderation Effects of Beliefs in the Benefits of Physical Activity “more intensive PA was related to a stronger belief in PA benefits, subsequently leading to reduced levels of depression and anxiety.” https://t.co/JBF1kDolZa
Mastering Managing Up: Purposeful Leadership Beyond Your Role
What do you think of "managing up"? Not your job? Something you do on purpose? I really liked this post from @wes_kao who explains what it's about, why it's important, and how to do it well. https://t.co/LlgRsfCQf4
Arsenal's Daily Therapy Turns EPL Into Drama
MyPOV - Daily therapy sessions for @Arsenal players and staff are now more than appropriate. Glad to see some suspense in the EPL. https://t.co/jjWTXiUSTy
First Cruise Was Surreal, I'm Totally Hooked
this @virginvoyages x @tiktok creator cruise was the most insanely amazing and surreal 3 days of my life omg. this was my first cruise but it really made me love that kind of travel 🥹🥹 i know there’s drama around...
Stay the Course: Short Stress, Long‑term Payoff
Never quit something with great long-term potential just because you can't deal with the stress of the moment.
Fatherhood Mistakes Teach Coaching Over Control
Mistakes are part of fatherhood. Bernard Drew opens up about missteps and learning to coach instead of control. Listen in: https://t.co/LwahS0TaDx
Mustard Chicken Shows How to Build Perfect Flavor
Chicken with mustard doesn’t sound like much. Until you taste it. Poulet à la Moutarde is one of those dishes that quietly teaches you everything that matters. How to build flavor, balance fat and acid, and make chicken actually taste like...
Innovation Keeps Crop Yields Ahead of Climate Threats
Ryan is correct. Crop yields continue to outpace the downward pressure of climate change and look likely to for the foreseeable future. There is risk of tipping points, to be clear, and those grow as temperatures rise. As of now,...
AI Discovers Chromogranin A Shields Brains From Alzheimer’s
20 to 30% of older adults have full blown Alzheimer's pathology in their brains (plaques, tangles etc.). But they never develop symptoms and nobody knew why. An AI just read thousands of human brains and named the reason: a protein...
Kids Mirror Your Fear Response: Model Courage Over Safety
Your kids are watching how you respond to fear. Every time you play it safe they learn that safe is the goal. Every time you bet on yourself they learn that ownership is possible. Teach them with your actions.
Tim Cook Admits Maps Flop, Celebrates Apple Watch Triumph
NEW: As his tenure as CEO winds down, Tim Cook shared with employees his biggest mistake and proudest moment in the role over the past 15 years. Here’s what he said — https://www.bloomberg.com/news/articles/2026-04-22/tim-cook-regrets-maps-flub-sees-apple-watch-as-his-proudest-work?srnd=undefined
Paxlovid Showed No Hospitalization Benefit in Vaccinated Seniors
In 2 randomized, open-label trials of Paxlovid there was lack of evidence of reduced hospitalizations among the participants, who were age 50+ with coexisting conditions, and who were vaccinated. The endpoint was very low (<1.2%) in the treatment and control...