AI-Designed Enzymes Poised to Replace Petrochemicals in Everyday Products
The detergent you use. The fabric on your Gore-Tex jacket. The fragrance in your shampoo. For a century, making these products meant petrochemicals and harsh industrial chemistry. AI protein design is changing the underlying process. @ArzedaCo builds custom enzymes for real industrial conditions: the pH, temperature, and substrate concentrations that actually exist in manufacturing, not idealized lab settings. The proof is in deployment, not the preprint. @biopraxis, co-founder and CEO of Arzeda, presents at SynBioBeta 2026 alongside Neil Parry, R&D Director at @Unilever, Paul Bielewicz of W.L. Gore, and Guus Gerritsen of MANE, the global fragrance and flavor company. Moderated by @ElisabethBrier of Forbes. The question: when AI-designed enzymes show up in everyday products on shelf, what does that actually look like? SynBioBeta 2026 is May 4-7th in San Jose, California, you can learn more about the conference and get your tickets here: https://t.co/8abYWJ1GbK
KRAS Targeting Fuels $30B Valuation for RVMD
The race to catch KRAS, pancreatic cancer’s ‘greasy ball,’ and create the most promising drug in decades Or, how $RVMD is now worth $30B https://t.co/iFilUpezjn via @angRchen #AACR26
The Strokes Spark Controversy with Anti‑war Montage at Coachella
The Strokes Stir Political Passions at Coachella With Video Montage Condemning U.S. and Israeli Bombings in Iran and Gaza https://t.co/cKcO3p87ZW via @variety
True Connection Empowers, Attachment Traps
Connection VS Attachment Connection: • Present-Focused. • Vulnerability. • Freedom. • Heart-Centered. Attachment: • Fear-Based. • Transactional. • Possession. • Mind-Centered.
If Everyone Gets a Penthouse, No One Has One
“Everyone can have a penthouse if they want” So the building will just be all penthouses then? Then which one’s the real penthouse?
True Decisions Feel Like Bodily Relaxation, Not Approval
You'll know it's the right decision when your body relaxes, not when everyone agrees with you.
Mario Galaxy Film Hits $2B, Ranks
#TheSuperMarioGalaxyMovie wins weekend with $35M (-49%) as global total hits $747.5M as the franchise tops $2B to become #10 animated franchise all-time https://t.co/ry67xkq3do
Joy, Ignorance, Optimism: Early-Career Superpowers, Says Nvidia CEO
Nvidia CEO on the early career benefits and superpowers of joy, ignorance and optimism https://t.co/n4dgUEgWAa
AI's 15‑Year Journey and Future Unveiled
If you're interested in how AI grew up over the past 15 years, and where it's headed, this new book tells the story in a riveting, page-turner way. In the new Ground Truths with @scmallaby https://t.co/B7ElqyDBPM
USC Compound Halts Alzheimer-Linked Brain Inflammation
As a medical school professor at USC, this one is personal. My colleagues at Keck School of Medicine developed a compound that stops brain inflammation linked to Alzheimer's -- while preserving normal brain function. The target: cPLA2, an enzyme that drives inflammation...
Millennial Overwhelmed by Vitamin Craze, Wants Simplicity
As an elder millennial I am so overwhelmed with the vitamins and supplements. I take a multivitamin, fish oil, and collagen and now I’m like do I need 100 more things? Please say no.
Milan Design Week: Inspiring Masculine Architecture Mastery
My trips to Milan for Design Week always leave me feeling completely inspired. Milan has this imposing but balanced masculine architecture. You see up close the work of Piero Portaluppi (of which I’m a big fan), and Borsani, and Ponti… and...
QCTiP2026 Launches in Oxford with Five Quantum Talks
#QCTiP2026 is about to begin in Oxford. Given the rapid progress in the field, this conference on quantum computing theory in practice could hardly be more timely: https://t.co/FCb3yhGhgD was a real pleasure to host #QCTiP2025 in Berlin last year, and...
Default Function Values Can Quietly Corrupt Bioinformatics Analyses
1/ Bioinformaticians: The default value of a function could silently break your analysis. Here’s a real example. Let’s dive in. https://t.co/FqIgiOU47G
Two Decades Later, We Still Explore Meditations Together
My wife samagerie bought this copy of Meditations back in 2007 just a month or so after we met. I wrote this on a page when we were reading it together. Almost 20 years later, we’re still reading it, but...
Air France Cancels Business Ticket, Then Charges $1,800
Air France Cancelled A Business Class Ticket, Said They Could Fix It — Then Demanded $1,800 More To Travel Anyway - View from the Wing https://t.co/ifCmuZaDyQ
Check Out Klipsch X Devon Ojas K0‑R2 Speakers in Milan
If you are in Milan this week you need to stop in to see the @klipschaudio x @devonojas kO-R2 speakers in the listening room at the Foundation Luigi Rovati 🔊 You can book an appointment on @devonojas profile 🔗
Behaviors Reveal Fear, Overwhelm, Stress, and Self‑Protection
Here's a quick behavior decode: Lying = they're scared of your reaction Not listening = they're overwhelmed, not ignoring you Whining = their nervous system is maxed out Hitting = big feeling, zero words for it Shutting down = the only way they know...
5 Hidden Lab Numbers Reveal Why You Feel Unwell
Your labs are "normal." But you haven't felt normal in years. There are 5 numbers your doctor probably isn't checking — and they tell a very different story. Free live webinar: May 5, 5 PM PT → 30dayhealth.co/webinar
From Foster Care to Neuroscience: A Success Story
What happens when a young person is released from the child welfare system? Join me with David Sussillo (@SussilloDavid) , a neuroscientist who has just written about his emergence from a difficult childhood to a successful life. https://t.co/CQWGwHcJHg https://t.co/f2Z0biRVw5
Space and Silence Reveal the Creative Stillness Within
Space and silence are two aspects of the same thing. The same no-thing. They are externalization of inner space and inner silence, which is stillness: the infinitely creative womb of all existence. - Eckhart Tolle https://t.co/uo7ENXqRv0
Wallace Explains Why Reading Feels Impossible Today
David Foster Wallace on why people struggle to read books: (this was filmed in 2003 but is even more true today) https://t.co/PorIzDMb0t
Leon Thomas' EP Overlooked Despite Strong Tracks
i thought that the ep leon thomas released last year had some of his best stuff, disappointing that its streams and radio play are nonexistent compared to mutt
Future Medicine Targets Aging, Not Just Symptoms
The future of medicine is treating causes, not symptoms. Aging is the main cause of disease
Gratitude Fuels Practical Optimism, Shifts Your Perspective
On this Sunday am ☀️ let’s be grateful for the sheer insanity of even being born, the odds are so outrageous … and so no matter the challenges and even worse, no matter the entitlement and audacity that run through...
V Discusses Solo Future and ‘Arirang’ Plans
My interview with V! We talked about the future of his solo career, working on ‘Arirang,’ and more Text: https://t.co/hcdMHpGxgH Video:
Regex Streamlines Bioinformatics ID Cleaning and Merging
🧵Regular expressions can save your bioinformatics analysis. Here’s how to use them to clean up messy IDs and merge datasets. https://t.co/tkYo7lRJCq
Adapt Training to Any Gym’s Equipment for Maximum Impact
I’ve trained people from four of the top MMA gyms. I’ve trained people inside the PI and the coaches knew about it (and are lovely people, shout out to the PI s&c staff). I’ve trained people in many small...
Two Nutritious Meals a Day Suffice for Desk Workers
For people with a desk job, which is 80% of us, two nutritious meals a day usually provide all the calories we need. If you overdo it one day, the next day eat less
Even Elite Athletes Want to Quit—Training Overcomes It
Every world-class endurance athlete I've asked says the same thing: They want to quit during a race It's natural to want to quit. Your brain is looking for a 'better' alternative to escape the threat of pain. Doubts are normal The best...
Productivity Surge Returns: Early Signs of New Boom
MS: We Are Likely in the Early Stages of Another Productivity Boom Productivity Growth Appears To Be Turning Higher Again https://t.co/M5GiqJzWRW
DASH and Anti‑inflammatory Diets Lower SCD Risk, Boost Cognition
Dietary Patterns and Indicators of Cognitive Function “healthy diets, exemplified by the DASH diet for blood pressure control and diets with lower hyperinsulinemia and inflammation potentials, were associated with a lower SCD risk and better cognitive function” https://t.co/Km7DxqqtJa
LV CEO Calls Repair Shops Loyalty Investment, Not Profit
Louis Vuitton CEO on investing in repair shops to build consumer surplus "This is a significant investment, by the way. This is not a profit center. This is something we invest to develop customer loyalty. So well, most of the repairs...
Order Set to Speed Psychedelic Drug Research Access
the order will dramatically accelerate access to new medical research and treatments based on psychedelic drugs
Growth Means Embracing Changing Opinions Over Time
Remember you have no obligation to maintain the same opinions you has 6 months ago. You have no obligations to maintain the same opinions you had 6 days ago. You should evolve. Your ideas should change. It's called growth.
BlueBird 7 Separation Unconfirmed, No Update From Blue
BlueBird 7 separation from the New Glenn second stage was scheduled for T+75 minutes, according to the timeline published before launch. But no updates from Blue on payload deployment or the earlier second burn of the upper stage.
Donut‑Shaped Phoenix Capsule Uses Inflatable Heat Shield
Phoenix space capsule: Donut-Shaped Capsule with Inflatable Heat Shield Returns Payloads to Earth by @spaceandtech_ #SpaceTech #AI #Engineering #Innovation #Technology https://t.co/WvjwMbAJaM
Educate, Act, Network: Blueprint to Escape Poverty
HOW TO GET RICH (and escape poverty): ☑ Step 1: Relentlessly self-educate like your livelihood depends on it (because it does). Books are free at the library. Podcasts are free. YouTube is free. Blog articles are free. ☑ Step 2: Take massive...
Glove Additives Mimic Microplastics, Complicating Detection
“…special substances added to disposable gloves to make them separate from molds more easily, called stearates, are chemically very similar to microplastics, making them almost impossible to distinguish in the lab.”
Morning Walk Sets the Tone for a Whole Day
"An early-morning walk is a blessing for the whole day." Henry David Thoreau 🌺 Please reply with a photo, an emoji, or words to describe what you saw on your walk today. 🚶♀️ #SundayMorning #walking #exerciseismedicine #health #pavingwellness #lifestylemedicine #ThinkBigSundayWithMarsha
Repay Early Belief by Becoming Who They Saw
There's something special about that one person who believed in you before anyone else. Before you had any evidence that their belief made sense. Before you even believed in yourself. That belief is a debt. You repay it by becoming...
Swap Overhead Press for Rotational, Stable Variations
Programming Around Shoulder Pain In The Overhead Press. Principles for success 1. Change The Angle: Landmine Press 2. Add Rotation: Arnold Press 3. Add Stability Requirement: KB Bottoms Up Press 4: Weight Bear: Pike To Toe Reach Real time problems require real time solutions
Postpartum Power Drink: Bone Broth, Goat Milk, Honey
I made up this postpartum morning drink and been loving it: - 1 cup bone broth - 1 cup goat milk - 1 to 2 tablespoons of honey - Pinch of salt It started as a postpartum recovery drink and I think it...
Old DSLRs, Custom Traps Reveal Masai Mara Secrets
'For nocturnal creatures, there's nothing better than camera traps' — how an award-winning wildlife photographer used old secondhand DSLRs and custom camera traps to make discoveries that 'stunned' Kenya's Masai Mara rangers https://www.techradar.com/cameras/photography/a-prize-winning-wildlife-photographer-used-old-secondhand-dslrs-and-custom-camera-traps-and-made-discoveries-that-stunned-kenyas-masai-mara-rangers
Courage Fuels Motivation when You Feel Stuck
If I have a motivation slump, I know I need to do something that takes courage.
Say No to Bad Opportunities, Attract the Right Ones
The moment you accept that not every opportunity deserves a yes… the right ones will start showing up on your calendar.
From Warm Battlefield Strolls to Chilly Night Winds
Yesterday was a rather warm day to walk around Kings Mountain National Battlefield. Today is Cowpens National Battlefield & a ride up to Saluda NC to the train museum. But first a trip to store for long pants...temp dropped overnight...
Rejuvenation Stems From Removing Old Blood, Not Young Transfusions
Munger was right to “avoid crazy” regarding young blood transfusions. While animal data is compelling, evidence shows rejuvenation (in mice) comes mostly from removing old blood components to dilute age-elevated factors. 🩸
Storytelling Gives Words to Understand and Redeem Ourselves
"One of the functions of art is to give people the words to know their own experience... Storytelling is a tool for knowing who we are and what we want." Ursula K. Le Guin on storytelling and the power of language...
Blue Origin Reuses New Glenn Booster, Boosting Launch Cadence
Well done to Blue Origin on successfully reusing a New Glenn booster for the first time, key to ramping up launch rate. https://t.co/n1kEUv1MlE