Mandalorian Pre‑sales Signal Weakest Star Wars Debut Yet
And yeah, ticket pre-sales kicked off on FRI for #TheMandalorianAndGrogu at US #BoxOffice, and oh boy… Unless #StarWars became less fanboy and more walk up heavy after 7 years absent from theatres, the MANDO film starring #PedroPascal might be on track to break #SOLO’s record as the lowest debut for the #StarWars franchise in the U.S. Pre-sales kicked off just 1.1x ahead of #MissionImpossibleTheFinalReckoning (and the #MissionImposdible movies are not nearly as fanboy heavy as a #StarWars film should be, and it was facing juggernaut #LiloAndStitch opening on the same weekend, while MANDO is all by itself). If things don’t improve, it might need the whole 4-day stretch to gross what #SOLO grossed its pure 3-day weekend. But not all is bad news, as the film should even so very likely debut within the Top20 biggest openings ever for that #MemorialDay 4-day holiday. It’s on course to beat #TheFinalReckoning and #XMenApocalypse 4-day openings as the #15 BIGGEST #MemorialDay EVER, but the big question is if it’s going to be able to challenge #BruceAlmighty & #TheDayAfterTomorrow’s overall debuts back in 2003 & 2004. #TheDayAfterTomorrow for instance had a 85.8M 4-day #MemorialDay & a 68,7M 3-day weekend. But there comes the catch: Differently from any #StarWars film prior to it, #MANDO built its audience across 8 years being the biggest live-action streaming series hit on #DisneyPlus, with Grogu specially being big among kids. We’ve seen recently how much franchises such as #Moana & #LiloAndStitch benefited from the exposition gained throughout #DisneyPlus when they finally returned to theatres. So I would not rule out completely the chance of MANDO ending up behaving like a family film rather than the typical fan-driven movie. In that case, the scenario would change completely, because families don’t buy in advance as much as fanboys rush to do. So what looks underwhelming now could in this case be just a demo metamorphosis, what could result in a slow burning pre-sales period and strong walk up business driven by families. If this becomes the case, a much better debut closer to #TheLittleMermaid’s territory could be in play, what would largely beat #SOLO’s debut. Right now though, I wouldn’t count on that unless the pre-sales trajectory shows that this could be the case. Also, as we always remind folks, this was just the first day of pre-sales, and so much can change depending on how well the marketing team plays their cards from now onwards. #TheMandalorianAndGrogu debuts on MAY 22
Quiet Moments Pack More Than Busy Days
One day, silence your phone. Leave it in the other room. Sit with your coffee or tea in the calm stillness of silence and watch the light in the room move across the floor. Nothing will happen. Yet you'll feel that...
Gates Foundation Funds One Quarter of Global Health
In my lecture this week on NGOs versus government programs in public health, I focused on the Gates Foundation. Why? Because ALONE they fund around 25% of all programs in global health. They have over $80 billion in assets and their operating...
Supplements Offer Small Endurance Gains, Unclear Adaptation Benefits
Supplements like sodium bicarbonate, beta-alanine, beetroot juice, and caffeine can boost endurance by ~1-3%. What about their impact on adaptation? Read the blog: https://t.co/nOvClAp15h https://t.co/R0OaDs8m92
NovaSeq 6000 Two‑color Chemistry Creates T>G Artifact
NovaSeq 6000's two-color chemistry introduces a recurrent T>G substitution artifact that doesn't show up on HiSeq X10's four-color chemistry. Germline and high-VAF somatic calls are fine. Low-VAF mosaicism calls are not. https://t.co/9PknN8Vyrb
Complexity Isn’t the Problem; Mindset Is.
Koan #55 “[process] isn't working.” “You're doing it wrong.” “But we got certified, read books, watched videos, and used templates.” "You're doing it wrong; it's more complex and subtle than all that.” "Then it's too hard to do right.” And the student was enlightened.
Fever in Babies Under 60 Days Signals Serious Risk
🚨Fever in young babies should be taken seriously. Infants less than 60 days old are very susceptible to serious infections like blood infection. Sometimes feve
Fertility Journey Delayed: Three IUIs Failed, Awaiting FET
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Kids Can Be Scared and Brave Simultaneously
Your child needs to hear, "Being scared and being brave can happen at the same time."
Overexplaining: A Nervous System Habit, Not a Personality Trait
I'm a neurodivergent health researcher. Here are 9 ways overexplaining is a learned nervous system habit, not a personality trait (and what you can do): 1. You explain your reasons before anyone has even questioned them (your body is bracing for misunderstanding...
Treat Your Inner Voice Like a Kind Friend
Our self talk speaks volumes. Be careful about the words you say to yourself. Use empowering language and be kind. A good rule is to speak to yourself the same way that you would speak to a dear friend. #SaturdayMorning...
Writing Demands Deep Self‑Listening and Embracing Shadows
Enjoyed @Joseph_Fasano_ inspiring advice to an inquisitive #writer. Sharing fragments for insight: -writing is witnessing -the life of a writer is learning to listen deeply to the self -rid yourself of old ghosts -Hope, but don't turn from the shadows #myprocessingchilddeath https://t.co/urX6jXkvDG
Weekend Work Sprints Boost Weekly Productivity and Clarity
Waking up & getting tf after it. Love a good work sprint on a Saturday/Sunday. Those ~3 hours make the week way better. And gives me a clear head on the weekend. Monty loves it too. https://t.co/8vTogysPao
Speak the Host Language: A Timeless Immigrant Guideline
As an immigrant, outside of the home try to speak the language of your host country as an example to your children, and do your best to assimilate. These were the rules my most recent family to immigrate (over a century...
Never Confuse DNA Plus/Minus Strands Again
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Implausible Apple Cider Vinegar Weight‑Loss Study Retracted
Implausible Apple Cider Vinegar Weight Loss Study Retracted When a trial has results that defy basic biology, it’s reasonable to be skeptical. @PharmacistScott https://t.co/ahEkiEmP7l https://t.co/yVyazUwXou
Travel Becomes a Search for Lost Indian Childhood
Travel, for me, stopped being about destinations a long time ago. It became a proxy for a childhood I left behind in India in the 1990s and have never stopped looking for. I finally wrote about it. https://t.co/7OILYtgC5Y https://t.co/Cdz8xRAvOn
White Vs. Red: Which Grand Central Chowder Wins?
Which do you prefer at the Grand Central Oyster Bar, white or red clam chowder? https://t.co/01Gk5drvy7
Emotional Stability Beats IQ in Investing Success
“If you’ve got a 150 IQ and you’re in my business, go sell 20 or 30 points to somebody else because you really don’t need it. You need emotional stability. You need to be able to detach yourself from fear...
Stress Less: Be Selectively Ignorant, Focus Wisely
To reduce your stress, try not to have strong and loud opinions about everything. Smart people are selectively ignorant about most things, and focused on some things.
Early Saturday Wake‑ups: Parenting's Toughest Challenge
Change my mind: There’s nothing harder than waking up your tween aged daughter at 545am on a Saturday.
Keto Diet Induces Ulcerative Colitis Remission, Challenges Conventional Care
A ketogenic diet put his ulcerative colitis into complete remission — off all medications, confirmed on colonoscopy. Dr. Nick Norwitz (PhD Oxford, MD Harvard) explains why "evidence-based" care isn't always optimal care, how keto rewires the gut and brain, and...
Quiet Inner Strength Enables Thoughtful Decisions Under Pressure
True toughness is quiet and comes deep from within. It’s about making the right choice under stress, uncertainty and fatigue. It requires emotional control: cultivating the power to respond—not react—and thus making thoughtful, deliberate decisions during pressure-filled situations.
Magdalena Bay's 'Imaginal Disk' Debuts at 2026 Tribeca Festival
Magdalena Bay’s 'Imaginal Disk' movie will premiere this June at the 2026 Tribeca Festival https://t.co/MxyhjHE45o
Our Loss of Real Megafauna Makes Charisma Tragically Ironic
*Charismatic megafauna* is tragically funny given how many authentic members of that class we’ve extirpated.
Zeal Fuels Growth; Envy Drags Others Down
“Zeal is what spurs you to achieve more, to excellence. Envy is about destroying other people to bring them down to your level.” ~@costofglory
Choosing Patience over Anger when Kids Borrow Cars
When your kid is home from college and scratches the car while borrowing it for the weekend, what if you don't get upset?
Hemingway's Letter: Love Endures Beyond Death
"Very few people ever really are alive and those that are never die; no matter if they are gone. No one you love is ever dead." Hemingway's extraordinary letter to a couple who lost their son, crowned with his only overt...
Shame Undermines Sustainable Behavior Change in Healthcare
When someone uses shame as “motivation,” it usually means they don’t understand how behavior change actually works (and are completely ignoring the science behind it). Shame *might* get some short-term action… but it increases stress, avoidance, and all-or-nothing thinking. That's EXACTLY...
Neck Training Boosts Core Power and Overall Strength
Train the neck hard and irradiation spreads: stronger traps, tighter core, locked shoulders, better force through the whole chain. It’s not just protection it upgrades the system. Bonus? A thick, developed neck simply looks stronger and more capable. https://t.co/pyfiZS4v9u
Organizations Must Prioritize Licensed Professionals at Black Mental Health Conferences
If you want the Black community to take mental health care seriously then our organizations must do the same. Having national conferences that include panels on mental health topics without a licensed mental health professional present shows that you do...
Female Doctors Deliver Better Care, Yet Face Unrewarded Burden
Female doctors get their patients better outcomes. Female doctors do not outlive their male colleagues. The trade is not an accident. Dr. Noemi Adame, board-certified pediatrician and founder of Culver Pediatric Center, sat with this on The Podcast by KevinMD. ...
Small Choices Define Mastery, Not Grand Gestures
The real craft is in the small decisions: the extra set you didn’t skip, the cue you actually applied, the recovery you didn’t negotiate away.
Use Comparison as Cheat Code, Not a Trap
Comparison isn't the problem. How you use it is. Looking at someone and: • Feeling behind: Trap • Extracting their moves: Cheat code.
Three‑Minute Nightly Brain Dump Fuels Morning Writing
This dead-simple 3-minute habit has helped me write every morning for 90 minutes, no matter what. Here’s how it works: I don't: • Wake up • Open a blank doc • And start typing If I did, the dreaded blinking cursor on the blank page would...
Boost ROI with 2‑3 Weekly Hinge, Pull, Lunge Sessions
The BEST thing you can do for a 1x/ week client? Show them the value of 2-3 time per week by using the following blueprint for the BIGGEST ROI. 1️⃣ Hinge Emphasis 2️⃣ Pull Emphasis 3️⃣ Lunge Emphasis These movement patterns tend to...
Dad-Powered Pun Machine Sparks Eye Rolls and Laughter
The only machine that runs on bad puns and dad pride. Warning: side effects may include eye rolls, reluctant laughter, and an uncontrollable urge to tell your kids. App from Brian Briggs. https://t.co/nrOlnv1jue
Antibodies: Essential Protectors Often Misunderstood, Says Vonn
Our Immune Systems keep us healthy Antibodies are some of the key protectors to our health and wellness and also some of the most interesting and informative - but they can be misunderstood @lindseyvonn is talking about antibodies, and why they...
Hospitals Must Prioritize Nutrition, Not Just Medication
When are hospitals going to realise that good nutrition will support many patients to improve their health alongside meds. The food my mum is currently being served can only be described as cold, brown sludge.
104‑Year‑Old Sprinter Credits Sleep, Stress‑Free Life, Vodka
Stanisław Kowalski, a 104-year-old Polish guy set a European record in 2014 in the 100-meter sprint for the 100-year-old age group with a time of 32.79 seconds He says his secret is avoiding stress, lots of sleep, and the occasional vodka https://t.co/tyVGWukUTI
Side‑lying Nursing Adds an Hour of Precious Sleep
One thing I did not master until my third baby is side-lying breastfeeding. With my second I would get up and sit in bed every time the baby needed to feed at night. That is a lot of fully waking...
Whitman's Leaves of Grass Guides Authentic Self‑Discovery
Walt Whitman's field guide to being yourself – the trial and triumph of "Leaves of Grass" https://t.co/onkPp36yE5 #longreads #traversal
Embrace Discomfort: It's Essential for Growth
As Carl Jung put it, "Man needs difficulties. They are necessary for health." Yet most people instinctually avoid pain. This is true whether we are talking about building the body (e.g., weight lifting) or the mind (e.g., frustration, mental struggle,...
From Failed Startups to $3 Billion Success
This is the greatest comeback story in history: After his father's murder... This kid moved to America & lost his life savings on 3 failed startups. With nothing left, he had ONE final idea that turned into $3 BILLION. Here are his 3...
French Publishers Alarmed as Sansal Sparks Author Exodus
The Sansal virus is out of the bag. Even the French are finally waking up to his extremist agenda. Crise chez Grasset en France : après l'arrivée de Boualem Sansal, hémorragie d'écrivains https://t.co/WinzX1FoTC
Study Shows Modern Palestinians Share Iron Age Levant DNA
I sent a link to a peer-reviewed research paper from 2025 that shows modern Palestinians have strong DNA links to Iron Age inhabitants of the Levant. Apparently this is "misinformation".
Cross‑Disciplinary Maintenance Insights Boost Cybersecurity Programs
The Maintenance of Everything Studying how other fields think about maintenance and sustainment is extremely useful. These areas are rich in lessons to apply to cybersecurity. Stewart Brand’s Maintenance of Everything is a brilliant overview of many of these fields. It’s...
Sweetener and Plastic Microplastics Trigger Worm Obesity
Sucralose and PMMA Microplastics Synergistically Induce Obesity with Altered Locomotion and Metabolism in Caenorhabditis elegans https://t.co/TExtjah4cV
Sue Bird Urges Young Athletes to Bring Themselves Fully
Sue Bird Reminds Youth Athletes ‘You Have to Bring Yourself’ in Everything You Do (Exclusive) https://t.co/eTRHifYFEx via @sheknows
Trust Fuels Your Daughter's Journey to Independence
Supporting your daughter’s independence starts with trust. 🎧 Hear more in this episode: https://t.co/c39rpq5ZqO #ParentingJourney