
Jamie Luoto Fuses Gothic Pin‑Ups with Freudian Surrealism
Good morning from @jamie_luoto - a woman who is trying to meld the illustrational, the figurative, calendar art, pin-ups, the gothic and horror, with an under win of Freudian surrealism and self-consciousness.
Confidence Myths Debunked: It's Learned, Not Inherited
5 Common Myths About Confidence: 1. You Are Born With It. 2. You Need To Feel Confident To Take Action. 3. Confident People Are Never Insecure. 4. It Requires Being Loud Or Arrogant. 5. It Comes From Massive Success.

Great Ideas Rarely Stem From Sudden Lightning‑bolt Moments
When you think of a creative breakthrough, what do you picture? If you're like most people, you probably imagine a lone genius struck by a sudden flash of inspiration — the famous lightning bolt moment. But creativity researcher Dr. George Newman...
Janet Jackson’s ‘Would You Mind’ Gets Deep‑Cut Spotlight
I wrote about the Janet Jackson song that miscellaneous uncs were shooting poison during, "Would You Mind," for @Spin's Deep Cut Friday column this week: https://t.co/pcJXNqRJbm
International Mega-Analysis Shows Psychedelics Alter Brain Circuit Function
An international mega-analysis of psychedelic drug effects on brain circuit function lots of great researchers involved in this paper. (whole article) https://t.co/vKhH0duJqv
Let Kids Be Bored: It Sparks True Creativity
Every time I notice my son or daughter acting bored, I feel guilty and tempted to save them from it. If I am not busy, I will nudge them towards something. But when I am busy and just ignore it, they...
Embrace Interruptions: They Spark Your Best Creative Ideas
Interruptions are not the enemy of a productive day. They're often where the best creative work happens. At the studio we call them drive-bys. And rather than treating them as disruptions, we've built them in. Meetings happen with the doors open...
Music Becomes a Portal: Katie Greer's Mind‑Blowing Insight
I asked KATIE ALICE GREER about music as place-channeling and her answer really floored me https://open.substack.com/pub/thefutureisourstomake/p/one-question-interview-with-katie
AI Frees Time, Dissolving Work‑life Ambition Tradeoff
What will you do with the time AI frees up? I think this will be one of the most important questions of our time. And most people aren't asking it yet I'll be honest about where I've landed I rarely work past noon...
Emerging From Depression: The Unexpected Lightness
What It Felt Like to Come Back From Depression (Content note: this post includes discussion of depression, suicidality, and eating disorders.)

Use the 5‑by‑5 Rule to Reframe Worries
When you start to worry about something, use the 5-by-5 rule. Will this matter in 5 days? In 5 hours? In 5 years? Try to put things in perspective and look at the big picture. It's hard to do. Sometimes...
Love the Process, Not the Market, for Lasting Success
You have to love the game. You have to love figuring things out. You have to love the people you are working with. You DO NOT have to love the market you're in. You need to love the machine. You...
Foundation Pledges $1B, Faces Conflict-of-Interest Concerns
The foundation aims to disburse at least $1 billion over the next year. However, critics are still very concerned about conflicts of interest between the foundation and the for-profit OpenAI Group. Mike Scutari Reports: https://tinyurl.com/3aumvkb5 Related IP Resources: OpenAI Foundation -https://tinyurl.com/yck5tsmu Grants for Science...
Sex Drives Distinct Immune Aging Patterns and Disease Risks
The way our immune cells age differs substantially by sex, from single-cell analysis of ~1,000 people. Implications for propensity for autoimmune diseases (women), vulnerability to cancer (men), immunosenescence and inflammaging @NatureAging https://t.co/GjcuZ8luNM

Wedding Night Thriller Trailer Starring William Moseley Drops
Wedding Night Thriller 'An Enemy Within' Trailer with William Moseley https://t.co/T9E1LoaukR #AnEnemyWithin #WilliamMoseley #thriller https://t.co/6eserkFYkd
Personalized CRISPR Fixes Baby KJ’s Genetic Defect
In just 6 months a team at @ChildrensPhila & @PennMedicine designed a personalized CRISPR based Rx to correct the single misspelled letter in Baby KJ’s DNA that results in CPS1 deficiency. Recent advances in mRNA science & CRISPR gene...

Dreaming of a Colonial Bungalow Atop Tropical Mountains
My idea of Heaven is a simple British Colonial style bungalow high up in the mountains of a peaceful tropical country, with a large verandah, a terraced garden and breathtaking views. #architecture #British #colonial #verandah #garden

AI Predicts Heart Failure Five Years Early via CT
AI to detect risk of heart failure 5 years ahead of symptoms via CT scan epicardial fat tissue https://t.co/RuZu8pSIAy @JACCJournals https://t.co/Gz052Ajj4X

Metabolism, Not Plaques, Drives Early Alzheimer’s Decline
As a medical school professor, I now believe the biggest mistake in Alzheimer's research was ignoring metabolism. A comprehensive Frontiers in Neurology review makes the case clear: mitochondrial dysfunction and metabolic failure happen YEARS before amyloid plaques or memory loss. The evidence...
Ultrasound Enables Non‑Invasive Control of Body Cells
"Sonogenics" is an emerging scientific field that uses ultrasound to non-invasively control and manipulate specific cells in the body, such as neurons or heart cells

Reflecting on RHCP's Rise, Flea's HONORA, and Mixed Feel
Hey, I wrote about the recent Netflix doc about the Red Hot Chili Peppers' early years and Flea's solo album HONORA, with tangents on John Frusciante's solo output and my ambivalent feelings about this absurd (absurdly successful) band. https://t.co/qk1vyaAJGy https://t.co/o5HSjjtY8T
Hourly Walks Boost Uterine Blood Flow for Conception
We know that blood flow to the uterus directly affects endometrial thickness and implantation. We also know prolonged sitting reduces blood flow to your lower body. So if you are sitting at a desk for 8 hours a day without...

Pitching Is a Trainable Skill, Not a Fixed Trait
Loved reading @dannyfontaine's book "Pitch: How to Captivate and Convince Any Audience". I used to be terrified of pitching. During my first book tour (for my first book, Hooked), I realized that every talk I gave about the book was...

Quality Attention Beats Hours of Time Together
REAL ATTENTION MAY MATTER MORE THAN LONG HOURS TOGETHER. • Micro-moments build attachment. • Eye contact fills emotional tank. • Consistency > duration. • Presence beats proximity. Try tonight. #QualityTime #IntentionalParenting #AttachmentParenting #ParentLife #FamilyFirst
Kid Questions My Texan Fluency Before Book Festival
I was reminding my kid that I’m heading to Texas for a book festival this weekend & that I won’t see him for a few days but that I’d make sure to call and bring him back something. His immediate...

New Brutal Chinese Action Thriller Trailer Drops
Brutal Chinese Action Thriller Film 'The Butcher's Blade' Official Trailer https://t.co/jk8afzFZzP #China #TheButchersBlade #actionmovie #FengchaoLiu #FufuYuan #ShanshanChunyu https://t.co/aTvqyGwp1c
Set a Fixed Time and Place for Habits
A quick and easy tip for building habits that last: Pick a standard time and place to do it. It’s easier to wake up knowing “I exercise at 4 pm” than to decide each time when to fit a habit into your...

Strengthen Knees and Boost Ankle Mobility for Pain‑free Movement
Knee pain | knee stability routine 6 exercises to strengthen the muscles around your knees while improving ankle and foot mobility. Knee pain is often linked to poor control and limited mobility, not just the knee itself. Better mobility below and strength...

Target Insulin Resistance, Inflammation for Superior Diet Benefits
As a medical school professor, I teach my students about DASH, Mediterranean, and other "healthy" diets. They all help. But new research shows they're not targeting the right pathways. A massive study of 205,852 adults followed for 32 YEARS found that metabolic...
Open‑mindedness Matters More than Being Smart
“It’s less about smart versus not smart, and more about having an open mind versus not having an open mind.” ~@arbesman
The Weakest Link's Drive Shapes the Whole Squadron
Research out of the US Air Force Academy found that the motivation of the least fit person in the squadron determined how much the entire squadron improved (or didn’t) on their fitness tests. Surround yourself wisely.
Loyalty to Outdated Things Masks True Financial Health
Most people aren't broke. They're just loyal to things that stopped serving them years ago.
New Neuroscience Reveals Hidden Consciousness in Brain‑Injured Patients
In-depth piece in @nytimes - out yesterday - all about the neuroscience detecting covert consciousness after brain injury, and the ethics of communicating with these patients. Featuring (of course) the pioneering work of @Comadork @CIFAR_News https://t.co/lZw8eMaWOw
Children Deserve Inherent Worth, Not Earned Validation
Your child needs to hear, "Your worth isn't something you earn. You were born with it already."
Strict Diets Breed Guilt—Choose Flexibility over Perfection
It’s normal to have meals and full days of eating that aren’t “perfect.” 🚨The key is to make sure those moments don’t feel like you’re falling off the wagon. If the swing is so extreme that you have feelings of...
Tech Shows You Really Need Easy Training
On tech… The real purpose of lactate meters, metabolic carts, HR monitors, etc? To tell you: “Yes… you really do need to train that easy.” Without it, most athletes never figure that out.
Don't Stifle Kids' Passions over Fear of Mess
Life is too short to nix your children's interests because you don't want to del with mess afterward.
We’re Enough: Unity, Love, and Purpose Beyond Destruction
What I’ve learned from the Artemis II mission and Integrity crew: You are already enough. Science and faith can co-exist. The Earth has everything we need. Humans are meant to create, not destroy. Sending love to the moon expands joy. We will...
True “Pay Your Dues” Means Learning Professionalism, Not Token Effort
What Does It Really Mean To “Pay Your Dues”? It's really about learning how to be a professional, it's worth recognizing that there IS a bad version of paying your dues. https://t.co/WMeBzgXy76 #advicers
Turn Every Conversation Into Immediate Leadership Insight
Every conversation is an opportunity but most people miss it. Listen carefully. Suspend judgment. Crystallize the learning. The best leaders don’t take minutes to learn - they do it in seconds. https://t.co/fUU3FsJbX7
Senior Official Calls for Orion Valve Redesign, Embraces Transparency
During the final Artemis II mission briefing yesterday there were lots of questions about Orion's helium valves. Lower level officials were hesitant to provide too much information on the consequences. Halfway through the senior official on stage, Amit Kshatriya, clearly...
Upcoming arXiv Overlay Will Flag Errors in Papers
I expect that in a few months, someone will create an arxiv overlay that will summarize the small errors (or big ones) in each paper. That will be tremendously useful (once it's reliable).
Live Longer: Eat Less, Move More, Laugh Plenty
“The secret to living well and longer: eat half, walk double, laugh triple, and love without measure.”
Functional Training: Outcome‑Driven, Not Exercise Labels
The authors claim "strong evidence" or "significant impacts," but with fair-to-poor primary studies and no quantitative meta-analysis, this is optimistic. Limitations section in the paper itself notes small samples, lack of controls, and need for better research. Core Semantic Issue is...
Take a Break: Skip CPI, Play Golf
You know you don't have to write a 1000 word tweet or a new substack article on the CPI print right? Life has choices. Maybe go play or watch golf instead of jumping on the...
Write a Book in 30 Days: 7 Simple Steps
Want to write your first book by next month? Here's how (in 7 simple steps): I can now write an entire 228-page book in 30 days. After self-publishing 11 books, I developed a simple process. Here's my 7-step framework:
Alaska Lounge Reopens to Priority Pass at SFO, $15 Co‑Pay
Alaska Lounge Returns To Priority Pass At SFO With A $15 Co-Pay — After Pulling Back Flights There - View from the Wing https://t.co/iyQ5wPOBBI
Chang'e‑7 Mission Targets Lunar South Pole Exploration
The Planetary Society has a nice summary of what Chang’e-7 will do at the lunar South Pole. https://t.co/wmotppdsyf
Decorative Pillows: Style Over Sleep Comfort?
Why do girls want the bed to be full of decorative pillows that you don't use But then at night you have to remove all those pillows Like what's the reasoning here, it's completely form over function huh
Katherine Johnson Stresses Math's Vital Role in Space
Katherine Johnson, the brilliant mathematician who helped @NASA put a man on the Moon talks about the importance of math https://t.co/bgRPTeCXVc