Facile Green Biosynthesis of High-Purity Silver Nanoparticles Utilizing Bambusa Blumeana Using Response Surface Methodology
Researchers compared a hands‑on experimental protocol with a statistically modeled approach for green synthesis of silver nanoparticles using Bambusa blumeana leaf extract. The experimental route produced a sharp surface plasmon resonance at 400 nm with an absorbance of 4.2 a.u., yielding spherical particles 22‑41 nm in size and a –29 mV zeta potential. In contrast, the response‑surface‑methodology prediction generated a broader 425 nm peak, larger 49‑71 nm particles and a +14.7 mV zeta potential, indicating poorer stability. All synthesis variables—AgNO₃ concentration, extract volume, temperature, time, and pH—proved statistically significant.
Functional Trait Expression Determines Contrasting Temporal Trends of Lepidoptera Inside and Outside Protected Areas
Researchers analyzed a 1960‑2022 Lepidoptera dataset from northern Austria to assess how functional traits evolve inside versus outside larger protected areas. Inside protected zones, mean species body weight increased, while outside, host‑plant diversity and dispersal ability rose and monophagous species...
Vaginal Natural Orifice Transluminal Endoscopic Surgery versus Conventional Multiport Laparoscopy for Hemorrhagic Ovarian Cyst Rupture with Hemoperitoneum: A Multicenter Retrospective...
A multicenter retrospective cohort of 42 hemodynamically stable women compared vaginal natural orifice transluminal endoscopic surgery (vNOTES) with conventional multi‑port laparoscopy (CML) for ruptured hemorrhagic ovarian cysts. Operative time, blood loss and transfusion rates were statistically similar, while 12‑hour postoperative...
Determinants of Artificial Intelligence Adoption in Student Support Information Systems: Evidence From Vietnamese Higher Education
A new study of 450 Vietnamese higher‑education administrators, faculty and students investigates AI adoption in student‑support information systems. It finds that robust management information systems (MIS) improve data quality, which in turn raises AI readiness. While AI readiness correlates with...
Impact of Infertility Etiology on Clinical Pregnancy, Cumulative Live Birth Rate, and Time to Live Birth After IVF/ICSI: A Retrospective...
A retrospective cohort of 2,444 first‑time IVF/ICSI patients examined how infertility cause influences outcomes. Tubal‑factor infertility was most common (39.6%), while ovulatory dysfunction yielded the highest cumulative live‑birth rate (76.8%) and shortest median time to live birth (11 months). Diminished...
Laboratory Predictors of Sudden Unexpected Death in Patients Receiving Palliative Care.
A retrospective analysis of 530 palliative‑care patients identified laboratory markers that signal sudden unexpected death (SUD). Twenty‑one percent of the cohort experienced SUD, defined as death within 24 hours of a stable assessment. Multivariable modeling linked prior chemotherapy, serum sodium,...
The Development of Breast Apocrine Carcinoma (BAC) Score that Distinguishes Breast and Cutaneous Apocrine Carcinomas
Researchers have created a Breast Apocrine Carcinoma (BAC) score that reliably separates breast‑origin apocrine cancers from cutaneous apocrine carcinomas. The classifier was built from multi‑cohort transcriptomic data using a LASSO logistic regression model and leverages distinct hormone‑signaling and proliferative signatures....
Natural Disasters, Mineral Resources, and Armed Conflict: A Spatial Durbin Model Analysis of the African Great Lakes Region
The study applies a Spatial Durbin Model to panel data from 2000‑2023 across the Democratic Republic of the Congo, Uganda, Rwanda, Burundi and Zambia, examining how mineral resource dependence and natural disasters affect armed conflict. It finds that reliance on...
Neuroscientific Evaluation of Fear Appeal in Television Advertising: An Eye-Tracking and Biometric Study of Viewer Attention
A neuroscientific study of 28 participants used eye‑tracking and galvanic skin response to compare fear‑based versus neutral TV ads. Fear‑based spots produced faster initial fixations, longer dwell times, and significantly higher skin conductance, indicating stronger visual engagement and physiological arousal....
Discovery of Novel 11 Beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitor by Machine Learning Enabled Large-Scale Virtual Screening
Researchers applied a machine‑learning‑driven virtual screening workflow to the Mcule catalog of roughly 139.6 million compounds, ultimately identifying a single top candidate, MCULE‑6869845113, as a potent 11beta‑HSD1 inhibitor. The Gradient Boosting Classifier achieved an AUC of 0.88 and Matthews Correlation Coefficient...
Four Decades of Glioblastoma Targeted Therapy: A Bibliometric and Pharmacological Perspective on Translational Failure and Future Directions
Over the past four decades, more than 5,000 studies have examined targeted therapies for glioblastoma (GBM), yet clinical success remains elusive. The United States and China dominate the research output, with the field progressing through four phases: molecular discovery, first‑generation...
Cross-View Detection of Large Vessel Occlusion in Computed Tomography Angiography
Large vessel occlusion (LVO) is a leading cause of severe ischemic stroke and demands swift diagnosis. Researchers introduced a cross‑view detection system that independently scans axial, coronal, and sagittal CTA images, then fuses the results in a common 3‑D space....
Latent Profiles of Mindfulness and Psychological Capital Among Preschool Teachers: Associations With Perceived Organizational Climate and Occupational Well-Being
The study of 977 preschool teachers uncovered four distinct latent profiles combining mindfulness and psychological capital. Teachers with higher perceived organizational climate were more likely to belong to the resource‑rich profiles. Those in the high psychological capital groups reported the...
Clinical Efficacy Analysis of Single-Port Endoscopy and Unilateral Biportal Endoscopy in the Treatment of Lumbar Spinal Tuberculosis
A retrospective study of 48 lumbar spinal tuberculosis patients compared single‑hole split endoscopy (OSE) with unilateral biportal endoscopy (UBE). The OSE group (n=26) showed significantly shorter operative times, reduced blood loss, and faster early pain relief than the UBE group...
Dimensionless Numbers for Evaluating Mechanization in Agroforestry Systems Based on UN SDG Indicators
The researchers applied UN Sustainable Development Goal metrics and dimensional analysis to devise five dimensionless indicators for judging agricultural machinery in agroforestry systems. Testing three machines across two family‑farm agroforestry layouts revealed that smaller equipment, particularly a coastal brushcutter, delivers...
A Multi-Parametric Study of The Impact of Aβ on Astrocytes Ca2+ Oscillations Under Fuzzy Environment
Calcium signaling in astrocytes is essential for brain homeostasis, but amyloid‑β disrupts these oscillations, especially when extracellular potassium is elevated. Researchers built a multi‑parametric mathematical model that incorporates voltage‑gated channels, SERCA pumps, and mitochondrial fluxes, using triangular fuzzy numbers to...
Developing Drug System Standards in Primary Care Units Using the SMART Model: A Participatory Action Research Study in Northern Thailand
A pharmacist‑led quality improvement program called the SMART model was piloted in five primary care units (PCUs) in northern Thailand from January to September 2025. Using a participatory action research framework, the intervention targeted all five national pharmacy‑standard domains and...
Athletic Performance in Virtual Reality: The Use of Virtual Reality for Training in Professional Football Players
A quasi‑experimental study of 39 male footballers aged 18‑19 compared virtual‑reality (VR) assisted training with traditional drills and a control group. The VR cohort showed statistically significant gains in balance, speed and leg strength, while the traditional group only improved...
Analysis of the Production Cost of a Unit of Biodiesel Production in the Biodiesel Plant
The study evaluates the unit production cost of biodiesel at a Skopje, North Macedonia plant with a baseline capacity of 20,000 tons per year. It compares cost impacts of scaling the facility to 25,000 and 30,000 tons annually and examines how increasing...
Gesture Recognition Using EMGMOAT From Wrist Surface Electromyographic Signals
Researchers introduced EMGMOAT, a mobile convolutional model with attention, for hand‑gesture recognition using wrist‑surface EMG signals. Benchmarks show EMGMOAT outperforms classical classifiers, achieving the highest accuracy among four methods evaluated. A comparative study also found wrist‑collected signals consistently surpass forearm...
Automated Grading of Radiation Dermatitis in Breast Cancer Radiotherapy with Dual-Head Supervision and Rule-Based Fusion: A Multicenter Study
Researchers introduced a dual‑head deep‑learning framework with rule‑based fusion to automatically grade radiation dermatitis in breast‑cancer radiotherapy. The model was trained on 10,685 skin images from 1,021 patients and validated internally, externally, and across cancer types. It achieved 94.7% accuracy...
Enhanced Teleconnection Between El Niño and Northern South China Sea Shelf Winter SST During Positive Atlantic Multidecadal Oscillation
Winter sea surface temperatures on the northern South China Sea (NSCS) shelf are strongly linked to El Niño, but the strength of this teleconnection varies across multidecadal scales. Researchers found that during the positive phase of the Atlantic Multidecadal Oscillation (AMO)...
Suction-Assisted Ureteroscopy for Renal Stones &Le; 2 Cm: A Systematic Review, Bayesian Network Meta-Analysis and Meta-Regression
A Bayesian network meta‑analysis of 13 studies (2,694 patients) compared suction‑enhanced flexible ureteroscopy (FANS), direct in‑scope suction (DISS) and conventional URS for renal stones ≤2 cm. FANS demonstrated a 2.5‑fold increase in stone‑free odds and reduced operative time by roughly 4.5...
Optimizing Arsenic Removal Using Surface-Modified Magnetic Nanoparticles via Taguchi Experimental Design
Researchers enhanced iron‑oxide magnetic nanoparticles with humic acid, raising their specific surface area from 48.2 to 92.2 m²/g and dramatically improving arsenic(V) adsorption. Using the Taguchi experimental design, optimal conditions—pH 3, 5 g/L adsorbent dosage, 180 minutes contact time, and 20 mg/L co‑existing ions—delivered a...
Assessing the Role of Distinct Intra-Annual Inflow Patterns in Hydropower Scheduling Beyond Conventional Unevenness Metrics
A new study of the Longyangxia reservoir on the Upper Yellow River shows that intra‑annual inflow patterns, identified through k‑means clustering of 67 years of monthly data, significantly affect hydropower scheduling. Nine distinct patterns were found, and their frequency shifts...
Dynamical Analysis of Infectious Disease Models Considering Awareness Factors and Neural Network Numerical Simulation
The authors extend the classic SIR epidemic framework by splitting the susceptible pool into “aware” and “unaware” groups and embedding media transmission dynamics. Analytical equilibrium and stability analysis show that media exposure reduces the basic reproduction number (R0) and flattens...
Phenomic Prediction in Drought-Stressed Faba Bean Across Spectral, Structural, and Fused Canopy Predictors
The study evaluated scanner‑derived vegetation indices (VI), three‑dimensional (3D) canopy traits, and their fusion to predict agronomic and physiological performance of drought‑stressed faba bean. Combined VI + 3D models achieved the strongest predictive power, reaching an R² of 0.75 for total grain...
ORIS v0.1 — Open Radiographic Imaging Schema for Dental Panoramic Reports: A Digital Dental-Formula Analogue for Documenting Imaging Findings
The Open Radiographic Imaging Schema (ORIS) version 0.1 introduces a machine‑readable, MIT‑licensed framework for documenting dental panoramic radiograph findings. It assigns a six‑character universal code to each tooth position and defines 14 object types, covering natural teeth, implants, and prosthetics....
Synthesis and In-Vitro Cytotoxicity Evaluation of 1,2,3-Triazole Incorporated 1,3,4- Oxadiazole-Imidazole-Pyridine Derivatives as Anticancer Agents
Researchers synthesized a novel series of 1,2,3‑triazole‑incorporated 1,3,4‑oxadiazole‑imidazole‑pyridine compounds (27a‑j) and characterized them fully. In vitro cytotoxicity testing against MCF‑7, A549, Colo‑205 and A2780 cell lines showed that three analogues—27a, 27b and 27i—outperformed the reference drug etoposide. Compound 27a was...
Machine Learning and Uncertainty Quantification for Predicting Weld Bead Geometry of AISI 304L in Micro-Size A-TIG Welding
Researchers tackled the data‑scarcity problem in micro‑size A‑TIG welding by combining experiments with machine‑learning models to predict weld bead geometry for AISI 304L stainless steel. Using a 45‑run design matrix, they compared linear Ridge regression with nonlinear XGBoost, the latter achieving...
Soil Type and Wastewater Contaminants Drive Antibiotic Resistance Genes, Mobile Genetic Elements, and Bacterial Communities in Soil, Cilantro Rhizosphere, and...
A column experiment compared untreated and treated wastewater irrigation on two contrasting soils—sandy Leptosol and clay‑rich Vertisol—planted with cilantro. Spiking the water with antibiotics and disinfectants markedly increased the abundance of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs),...
Climate Variability in the Last 12,500 Years Has Shaped Vegetation Dynamics Differently Across West African Savannas and Forests
A new pollen‑based study reconstructs West African vegetation over the past 12,500 years, linking climate variability from the Younger Dryas to today with changes in savanna and forest plant communities. Researchers harmonised fossil pollen with TRY trait data, revealing that...
Rehabilitation of Achilles Tendon Injuries Through Patient-Specific Scaffold Design Using FDM-Based 3D Printing of Thermoplastic Polyurethane (TPU)
Researchers demonstrated that thermoplastic polyurethane (TPU) scaffolds fabricated via fused deposition modeling (FDM) can be customized for Achilles tendon repair. Patient‑specific designs using AutoCAD and Cura produced spiral and lattice geometries with semi‑crystalline structure, confirmed by X‑ray diffraction. SEM revealed...
AImoclips: Benchmarking Emotion Conveyance in Text-to-Music Generation Using a Dimensional Valence-Arousal Framework
Researchers introduced AImoclips, a benchmark that measures how well text‑to‑music generators convey emotions using a valence‑arousal framework. The study gathered 991 instrumental clips from six commercial and open‑source systems, each prompted with 12 emotion words, and collected 6,162 human ratings...
Financial Flexibility and Firm Performance: Evidence From an Emerging Market
A new study of 25 non‑financial BIST30 firms in Turkey, covering 2010Q1‑2025Q2, shows that return on assets (ROA) positively influences financial flexibility while leverage and firm size have strong negative effects. Net profit margin proved statistically insignificant. The research employs...
Spontaneous Ignition of Vertically Oriented Wood Exposed to Convection and Time-Dependent Thermal Radiation: Experimental and Analytical Prediction
Researchers examined spontaneous ignition of vertically oriented structural timber under combined transient thermal radiation and cross‑wind. Using five heat‑flux increase rates and five wind speeds, they measured surface temperature, mass‑loss rate, and ignition time, then validated a one‑dimensional heat‑conduction model....
Development of a Predictive Nomogram for Intraoperative Massive Transfusion in Patients with Placenta Accreta Spectrum: A Retrospective Cohort Study
A retrospective cohort of 87 placenta accreta spectrum (PAS) patients identified a 36.7% incidence of intraoperative massive transfusion. Using LASSO and multivariate logistic regression, the authors built a nomogram incorporating gestational bleeding, pre‑operative hemoglobin, and PAS subtype (increta/percreta vs. accreta)....
Effects of Calcium Channel Blockers on Intracellular Calcium Distribution and Expression of Calcium Signaling-Related Genes in Sophora Tonkinensis
Researchers treated Sophora tonkinensis with three calcium‑signaling inhibitors—LaCl₃, Na₃VO₄, and EGTA—to map subcellular calcium distribution and gene expression over 20‑60 days. LaCl₃ triggered early calcium buildup then activated alternative efflux in leaves and extracellular deposition in root tips. Na₃VO₄ caused...
Single-Cell Dissection of BCAA Metabolism Unveils ACAT1-Dependent CS Acetylation as a Metabolic Checkpoint for Immunosuppression in Prostate Cancer
The study applied single‑cell RNA sequencing to stratify prostate cancers by branched‑chain amino‑acid (BCAA) catabolism and discovered that BCAA‑HIGH tumors suppress CD8⁺ T‑cell infiltration, cytotoxicity, and proliferation. Mechanistically, high BCAA levels activate ACAT1, which acetylates citrate synthase (CS), raising CS...
Network Architecture Determines Delay Robustness in the Spindle Assembly Checkpoint
The preprint introduces a distributed‑delay framework to study how timing lags affect the spindle assembly checkpoint (SAC). By embedding experimentally realistic delays into several mechanistic SAC models, the authors discover two distinct architecture classes: delay‑robust designs that sustain strong APC/C...
Balancing Ecosystem Carbon Storage and Economic Development: An Environmental Disparity Perspective in China
A new study quantifies the spatial mismatch between ecosystem carbon storage and economic output across China. Western regions hold 74.6% of the nation’s carbon stocks but generate less than 5% of carbon‑adjusted GDP, while the east dominates carbon‑adjusted GDP with...
Effects of Standardized Near Activities on Retinal and Choroidal Structure, Microcirculation, and Visual Outcomes in Children with Anisometropic Amblyopia: Study...
A prospective, single‑center randomized trial will enroll 80 children with hyperopic anisometropic amblyopia to evaluate whether a standardized 15‑minute near‑activity task, added to conventional patching, produces measurable changes in retinal and choroidal structure and microcirculation. Optical coherence tomography and OCT‑angiography...
Multi-Scale Thermal Homeostasis: Plants Achieve Temperature Control Through Hierarchical Regulation
Researchers combined custom nanothermometric probes with time‑gated imaging to map internal temperatures of living plants. In Nicotiana benthamiana leaves, a 21 °C external swing (24 °C → 45 °C) produced only a 10 °C rise near the cell wall, less than 7 °C in the cytoplasm, and...
Impact of Maternal Thyroid Dysfunction on Neonatal Thyroid Profile and Blood Glucose Levels: A Comparative Study
A prospective study of 100 newborns compared infants of mothers with hypothyroidism to those of euthyroid mothers. Neonates of hypothyroid mothers exhibited significantly higher TSH (8.42 mIU/L vs 5.61 mIU/L) and lower FT4 (1.21 ng/dL vs 1.48 ng/dL). Their blood glucose at two hours...
Knowledge, Attitude, and Practice Regarding Multi-Parameter Monitor Alarms Among ICU Nurses: A Multi-Center Cross-Sectional Study
A multi‑center cross‑sectional study of 813 ICU nurses in nine Chinese tertiary hospitals measured knowledge, attitudes, and practices (KAP) toward multi‑parameter monitor alarms. The average KAP score was 66.22 ± 6.70, translating to an 80.76% score rate, indicating a moderate competency level....
Internet of Things and Artificial Intelligence for Carbon Emissions Monitoring and ForecastingA Systematic Review of Smart Environmental Accounting Systems
A systematic review of 100 peer‑reviewed studies finds that Internet of Things (IoT) sensor networks enable real‑time carbon emissions monitoring, while artificial intelligence (AI) models can reliably forecast emission trends. The analysis highlights strong performance in data collection and prediction...
Soil-Transmitted Helminth Contamination Around Sanitation Facilities in Ile-Ife, Nigeria: The Role of Latrine Type, Soil Characteristic, and Community Knowledge
A cross‑sectional study of 200 households in Ile‑Ife, Nigeria, found 78.5% of soil samples within 100 m of latrines contaminated with soil‑transmitted helminth eggs, chiefly Ascaris lumbricoides and hookworm. Pit latrines showed the highest mean egg count, while pour‑flush latrines had...
MDT-Based Comprehensive Management of Type 3 Von Willebrand Disease in Pregnancy: From Preimplantation Genetic Testing to Antenatal Care, Delivery and...
Researchers reported the first use of recombinant von Willebrand factor (rVWF) in China to manage a pregnancy complicated by type 3 von Willebrand disease. A 36‑year‑old patient conceived via IVF and received target‑guided rVWF dosing before amniocentesis and elective caesarean, achieving activity...
Patient Perspectives on Gene Therapies and Gene Editing for Familial Cardiomyopathies
Early‑phase trials are testing gene replacement and editing for hypertrophic and dilated cardiomyopathies, yet patient viewpoints remain understudied. Interviews with 21 adults (average age 57, 57% female) revealed four decision drivers: perceived disease severity, quality‑of‑life impact, treatment safety and delivery,...
Favorable Long-Term Functional Outcome Following Left-Sided Compartmental Epaxial Muscle Resection (T13-L7) for a Longissimus Lumborum Liposarcoma in a Dog: A...
A 10‑year‑old Border Collie was diagnosed with a well‑differentiated liposarcoma spanning the left longissimus lumborum from L1 to L6. Surgeons performed a unilateral compartmental excision of the multifidus, longissimus and iliocostalis muscles, managing intra‑operative hemorrhage with a blood transfusion. Post‑operative...