Inside India’s $1 Trillion Venture Revolution W/ Kalaari Capital, General Catalyst, DM Gupta & Lightspeed India
The episode examines India’s rapidly evolving venture ecosystem, highlighting how women investors and family offices are driving a shift toward a $1 trillion wealth era and reshaping where capital flows. Panelists Vani Kola, Priya Mohan, Aarti Gupta, and Shruvi Shrivastava discuss the need to democratize opportunity, rethink traditional venture models, and leverage the power of smaller funds and premiumization in tech. Insights include the impact of the General Catalyst‑Venture Highway merger, the rise of family‑office‑backed investments, and the importance of inclusion in scaling Indian startups. The conversation underscores that women leaders are at the forefront of this transformation, offering fresh perspectives on scaling capital and innovation in India.
Rocket Mortgage CEO: Here’s How to Fix the Housing Crisis
In this episode, Alex Rampell and Rocket Mortgage CEO Varun Krishna dissect how asset inflation has turned homeownership into a wealth‑transfer mechanism, pushing the median first‑time buyer’s age from 30 to 38. They explain Rocket’s strategy of owning the entire...
#174 Investrio: QuickBooks for the People
In this episode, founders Joyce and Laura pitch Investrio, an AI‑driven bookkeeping platform designed to replace clunky finance tools like QuickBooks for solopreneurs. They explain how the product automates expense tracking, tax prep, and cash‑flow insights, and discuss early traction...
Lee Edwards of Root VC: "Let's Get Technical!" -- An Engineer Becomes a VC
In this episode, Lee Edwards, a former CTO and mechanical/software engineer turned General Partner at Root VC, shares how his hands‑on engineering background informs his seed‑stage investing in deep‑tech, AI, and devtools. He dives into the value of pair programming,...
Founder10x - From $500M Exit to Reinventing Software - Shay Levi, Co-Founder & CEO, Unframe
In this episode, Shay Levi recounts his journey from co‑founding Noname Security, which sold to Akamai for $500 million, to launching Unframe—a venture that promises to build custom software for free and charge only when it delivers measurable impact, leveraging AI...
How to Get Funded Now: VCs Reid Hoffman, Aileen Lee, and Stacy Brown-Philpot, with Van Jones
In this Masters of Scale session, Reid Hoffman, Aileen Lee, and Stacy Brown-Philpot discuss how venture capital strategies have shifted in 2025, emphasizing a more selective, founder‑centric approach amid rapid AI growth. They outline the key green‑lights—clear product‑market fit, defensible...
E649 | Mariette Roesink, Curie Capital: Backing Life Sciences, Unicorns & Zero Bankruptcies
Mariette Roesink, co‑founder of Curie Capital, explains the firm’s biotech‑focused VC model that seeks both outsized financial returns and meaningful patient outcomes. She showcases a track record of two unicorn exits, €200 M raised in a single year, and zero bankruptcies...
From Yext to Roam: Howard Lerman’s Second Act
In this episode, Howard Lerman reflects on the challenges of launching a second venture after Yext’s success, describing how he founded Roam as an AI‑augmented "Office of the Future" that lets people work from anywhere. He discusses the solitude that...
20VC: Benchmark's Newest General Partner Ev Randle on Why Margins Matter Less in AI | Why Mega Funds Will Not...
In this episode, Benchmark GP Ev Randle argues that traditional profit margins matter less for AI startups, emphasizing growth, data advantage, and network effects over short‑term profitability. He warns that mega‑funds will struggle to deliver strong returns because capital scarcity...
Collection: Curate People
In this episode, Naval and host Nivi argue that recruiting is the founder's most critical, non‑outsourcable function, shaping a startup's DNA and ensuring a high‑performing, low‑ego team that can execute the product vision. They stress that early hires must match...
20Sales: Why You Need a CRO Pre-Product | Why Remote Sales Teams Do Not Work | How Snowflake Built a...
In this episode, host Harry Stebbings and sales veteran Chad Peets explore why SaaS startups should appoint a Chief Revenue Officer before product launch, argue that fully remote sales teams often fail without strong structure, and dissect how Snowflake engineered...
Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease
Mark Zuckerberg and Priscilla Chan explain how the Chan Zuckerberg Initiative is creating AI‑driven computational tools—like the open‑source Cell Atlas and virtual cell models—to accelerate discovery, test high‑risk hypotheses in silico, and ultimately cure, prevent, and manage all disease by...
VC10X Micro - The Reason Behind 100,000 Layoffs in 2025 - VC10X Micro
In this micro‑episode, Prashant Choubey explains why even profit‑rich giants like Meta and Amazon are cutting thousands of jobs in 2025, attributing the wave to three forces: the "Great AI Re‑allocation" that shifts talent to automation, a newly permanent "Year...
From Billion-Dollar Brand to Blank Slate: Bobbi Brown’s Comeback
In this episode, Bobbi Brown recounts how she grew Bobbi Brown Cosmetics into a billion‑dollar powerhouse and the fraught split with Estée Lauder that forced her to choose between retirement and reinvention. She shares hard‑won lessons on scaling a brand, navigating...
Seeing The Future From AI Companions to Personal Software
In this episode, Eugenia Kuyda, the founder of Replika and CEO of Wabi, discusses how AI‑driven personal software will shift from a developer‑only tool to a creative medium accessible to anyone, likening command‑line AI interfaces to the early days of...
#173 STAG: The Tesla of Construction Equipment?!
In this episode, founders Adam and Patrik pitch STAG, an electric mini skid‑steer they describe as the "Tesla of construction equipment," highlighting its multi‑function design, Made‑in‑USA manufacturing, and early traction with major dealers like Bobcat. They explain the market opportunity...
E646 | Alper, Agave Games & Enis Hulli, E2vc: Pivoting Models & Building Global Gaming Success From Turkey
In this episode Alper Oner, co‑founder of Agave Games, and VC Enis Hulli discuss Agave’s evolution from a publisher to an in‑house studio that struck global success with the hidden‑object hit “Find the Cat” and is now scaling its next...
ElevenLabs CEO: Why Voice Is the Next AI Interface
In this episode, ElevenLabs CEO Mati Staniszewski explains how his small, autonomous, globally‑hired team ships research‑grade AI—text‑to‑speech, licensed AI music, and real‑time voice agents—at lightning speed, arguing that voice will become the primary human‑computer interface. He details the Voice Marketplace’s creator‑centric...
The Startup Building Edible Insulation to Tackle a 1.4 Gigaton CO2 Problem
In this episode, host Tom Britton talks with Theresa Hoffmann, founder of Nanoplume, about their bio‑aerogel insulation that is three times more effective and 60% thinner than conventional materials, a non‑toxic product so safe she even eats it during demos....
VC10X - What Is A Continuum Fund? - Michelle Urben, Managing & General Partner, Synergos Fund
In this episode, Michelle Urben explains Synergos Fund’s "continuum fund" model, which provides patient, evergreen capital to companies from seed through commercialization, rejecting the traditional exit‑focused VC mindset. She highlights how the fund aligns with conscious capitalism, offering flexible, transparent...
David Sacks: AI, Crypto, China, Dems, and SF
In this episode, White House AI and Crypto Czar David Sacks joins Marc, Ben, and Erik to dissect the Trump administration’s approach to AI and crypto, highlighting a regulatory capture strategy by major AI firms. He argues that open‑source technology...
Rebuilding Front for the AI Era | CEO Dan O’Connell
In this episode, Dan O’Connell, the new CEO of Front, discusses how the company is navigating the AI revolution by balancing legacy systems with innovative technology, emphasizing that the toughest part of transformation is deciding what to let go of....
Why Speed, Not Size, Will Define the Next War
In this episode, Horacio Rozanski of Booz Allen Hamilton and Gary Shield of Shield AI explain how speed, software agility, and public‑private partnerships are reshaping U.S. defense amid rising global tensions. They draw lessons from the Ukraine and Taiwan conflicts,...
Beyond Chatbots: Marc Andreessen and Ben Horowitz on AI's Future
In the closing keynote of a16z’s Runtime conference, host Erik Torenberg chats with co‑founders Marc Andreessen and Ben Horowitz about the event’s highlights, the current capabilities of large language models, and why massive AI capital expenditures don’t signal a bubble....
20VC: Tim Ferriss: Why I Walked Away From Angel Investing After Uber | How I Accidentally Lost $150 Million |...
In this episode, Tim Ferriss reflects on why he stepped away from angel investing after his early involvement with Uber, recounting a costly $150 million mistake and how money both solved and later complicated his personal challenges. He shares insights on...
VC10X Micro - Intel's Epic Turnaround: Up 100% in 6 Months📈🤯
The episode dissects Intel’s dramatic reversal from an $18.8 billion loss to a $4.1 billion profit in six months under new CEO Lip‑Bu Tan, highlighting his outsider‑driven turnaround playbook that emphasized strategic capital, ruthless focus, and rapid execution, even attracting a $5 billion investment...
"Is There an AI Bubble?” Gavin Baker and David George
In this a16z Runtime conversation, Managing Partner Gavin Baker and GP David George examine the macro forces driving the AI surge, including the trillion‑dollar data‑center expansion and shifting economics of GPU pricing. They assess whether the rapid growth signals a...
E643 | Sebastian Peck, KOMPAS VC: Europe’s Industrial Tech Moment: Decarbonisation, AI & the Risk Appetite Gap
In this episode, Andreas Munk Holm talks with Sebastian Peck, a partner at KOMPAS VC, about why industrial tech—focused on decarbonisation, productivity and resilience—is finally gaining traction in European venture capital. Peck highlights the divergent energy strategies across regions, the...
20VC: A16z Raises $10BN in New Funds | Mercor Raises $350M at a $10BN Valuation | OpenAI Restructuring: Who Wins...
The episode breaks down four major topics: OpenAI's restructuring and its impact on stakeholders; Andreessen Horowitz's $10 billion fundraise; Mercor's $350 million raise at a $10 billion valuation; and a critique of IRR as a VC metric, followed by three actionable strategies to...
Building the Real-World Infrastructure for AI, with Google, Cisco & A16z
In this episode, a16z’s Raghu Raghuram talks with Google’s Amin Vahdat and Cisco’s Jeetu Patel about the massive physical build‑out required for AI, covering everything from custom chips and power grids to global data‑center networks. They frame this as an...
#172 My Town AI: ChatGPT Meets SimCity
In this episode, founder and mayor‑pro‑tem Nichole Sterling pitches My Town AI, an AI‑driven civic‑intelligence platform that gives small towns access to data, workflow automation and low‑cost digital twins to solve grant‑writing bottlenecks and operational blind spots. She illustrates how...
How Anastasia Soare Built a Beauty Brand Worth Billions
In this episode, Anastasia Soare recounts her journey from a Romanian immigrant running a one‑room Beverly Hills salon to creating a global beauty empire valued at roughly $3 billion, highlighting the power of relentless focus on a niche—eyebrows. She shares key...
Founder10x - Can AI Beat The Top Investors? - Jan Szilagyi, Co-Founder, Reflexivity
In this episode, Jan Szilagyi, co‑founder of Reflexivity, explains how his AI‑driven market research platform transforms raw market data into an analytical partner for top hedge funds, embedding principles from legends like Stanley Druckenmiller. He details the platform’s differentiation, its...
Chobani & Patagonia CEOs Break Down Where Values Meet Profit
In the episode, Patagonia CEO Ryan Gellert and Chobani founder Hamdi Ulukaya discuss how they align values with profit, navigating activist government pressure and anticipatory compliance while scaling their businesses. They share strategies for integrating environmental stewardship and immigration support...
Raghu Raghuram: AI, Robotics, and the Rebirth of Infrastructure
Raghu Raghuram reflects on his front‑row experience of the early internet wars, the Netscape‑Microsoft browser battles, and the landmark VMware acquisition of Nicira that reshaped networking. He and the a16z hosts discuss how VMware grew from a modest startup to...
ElevenLabs’ Vision for Voice Interfaces | CEO Mati Staniszewski
In this episode, ElevenLabs co‑founder and CEO Mati Staniszewski discusses how the company’s emotion‑driven voice AI is reshaping sectors such as personalized healthcare and film production. He explains the technology’s ability to generate nuanced, expressive speech that can adapt to...
20VC: Sequoia's David Cahn on The Winners and Losers in AI | The $0-$100M Revenue Club: Is Triple, Triple, Double,...
In this episode, Sequoia partner David Cahn argues we’re in an AI bubble but sees lasting moats in physical data‑center infrastructure, while mapping out which companies will thrive or falter as AI reshapes markets. He discusses the impact of big‑tech...
20Growth: How to Build a Paid Marketing Machine: ROAS (Return on Ad Spend) 101 | The Rise of User Generated...
In this episode, growth veteran Sandy Diao shares the biggest lessons she learned scaling products at Pinterest, Meta, and Descript, emphasizing how to craft strong growth hypotheses and avoid common strategic pitfalls. She breaks down the fundamentals of Return on...
20VC: Why VC Today Is Worse Than 2021 | Why Vertical SaaS Is a Bad Investment Today | Why We...
The episode critiques the current venture‑capital climate, arguing it’s as over‑hyped as the 2021 COVID boom and warning that vertical SaaS and legal‑SaaS investments are now unattractive. Host Harry Stebbings and guests discuss Revolut’s $3 bn raise at a $75 bn valuation...
Marc Andreessen and Amjad Masad: English As the New Programming Language
In this episode Marc Andreessen, Erik Torenberg, and Replit CEO Amjad Masad explore how AI agents are reshaping programming, arguing that English‑based prompts are becoming the new coding language. Masad explains how reinforcement learning unlocked reasoning in large models, how...
Why Creativity Will Matter More Than Code
In this episode, a16z partner Anish Acharya and host Kevin Rose discuss how AI is sparking a new consumer technology renaissance, emphasizing that the next wave of products will blend emotion, utility, and creativity rather than just code. They explore...
#171 Doctours: VC Funded Hair Transplants?!
Doctours founder Girum shares his personal experience with medical tourism that saved his brother, launching a marketplace that matches U.S. patients to vetted overseas clinics, starting with elective hair‑transplant procedures in Turkey. The platform handles patient intake, clinic verification, reviews,...
Temperate: The Tech Beaming Heat Into Space to Disrupt the Trillion-Dollar Cooling Market | Angel Insights
The episode spotlights several deep‑tech and angel‑investment stories, beginning with Charlie of Temperate who converts heat to light and beams it into space, offering a refrigerant‑free cooling system up to 20× more efficient for data‑centers and HVAC markets. It then...
Founder10x - Are AI Agents The Future of Doctor's Office? - Ganesh Padmanabhan, Founder, Autonomize AI
In this episode, host Prashant Choubey talks with Ganesh Padmanabhan, founder of Autonomize AI, about the emerging role of AI agents in medical practices. They explore how autonomous AI assistants can handle patient triage, appointment scheduling, and routine follow‑ups, potentially...
How Kong Was Born: APIs, Hustle, and the Future of AI Infrastructure
In this episode, a16z host Martin Casado interviews Kong co‑founder and CEO Augusto "Aghi" Marietti about his journey from a Milan garage to building a leading API infrastructure firm, highlighting the relentless grind, near‑death moments, and the bootstrap funding that...
Reid Hoffman on AI, Consciousness, and the Future of Humanity
Reid Hoffman, alongside Erik Torenberg and Alex Rampell, explores how AI will transform work, science, and humanity, emphasizing that the most impactful breakthroughs will arise beyond obvious productivity tools. They discuss current AI’s reasoning limits, debate whether consciousness is required...
95% Faster Video Production with Synthesia | Victor Riparbelli
In this episode, Victor Riparbelli, co‑founder and CEO of Synthesia, explains how his AI‑driven platform lets anyone create video without cameras, cutting production time by up to 95% and opening new possibilities for content creators. He and Kleiner Perkins partner...
20VC: The Startup Adding $1M ARR Every Week | Competing Against OpenAI's Codex and Claude Code: Who Wins | Why...
In this episode, host Harry Stebbings talks with Zach Lloyd, founder and CEO of Warp, about the startup’s rapid growth—adding $1M ARR each week—and its battle against AI coding assistants like OpenAI's Codex, Anthropic's Claude, and Google's Gemini. Lloyd explains...
Keith Rabois: Israel, OpenAI, Opendoor, and DOGE
Keith Rabois argues that the U.S. is on the cusp of a new AI‑driven economic expansion that could boost GDP growth to around 5%, emphasizing the rise of sovereign AI projects and the nation’s ability to grow out of debt....
Brené Brown & Reid Hoffman on the Skills Every Leader Needs Now
In this 23‑minute conversation, Brené Brown and Reid Hoffman explore the essential, often overlooked skills leaders need today, emphasizing courageous vulnerability, active listening, and the power of compassion. Brown argues that true leadership thrives on empathy and psychological safety, while...