Today's Healthcare Pulse
Abridge teams with Eli Lilly and Nvidia to expand AI scribe platform
Abridge announced a strategic investment from Eli Lilly and a partnership with Nvidia to build a foundation model for clinical conversations. The collaboration aims to broaden Abridge’s AI‑scribe services across more health systems and integrate with payers. The company already supports over 300 health systems.
Also developing:
Are Complete Dentures Right for You? Key Benefits Explained
The American Dental Association reports roughly 40.2 million U.S. adults are edentulous, underscoring a sizable market for tooth replacement. Modern complete dentures have evolved with digital scanning, computer‑aided design, and customized aesthetics, delivering better fit, comfort, and facial support. Immediate dentures bridge the gap after extractions, preserving confidence while tissues heal. Compared with implants, dentures remain the most affordable, quickly delivered solution, though they require ongoing maintenance to sustain function and appearance.
Op-Ed | Dietary Guidelines for (Some) Americans: The Impact of Ignoring Health Equity in the DGA
The 2025‑2030 Dietary Guidelines for Americans (DGA) rejected 30 of the 56 recommendations from the Dietary Guidelines Advisory Committee (DGAC) after labeling the committee’s health‑equity focus as biased. Instead, the administration relied on a newly commissioned “Scientific Foundation” report that...
Glaukos to Present Multiple Scientific Abstracts at the 2026 American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting
Glaukos Corporation will present a slate of scientific abstracts at the 2026 American Society of Cataract and Refractive Surgery (ASCRS) meeting in Washington, D.C., and will exhibit at booth #407. The company is also sponsoring an educational symposium on Epioxa™,...
Bausch + Lomb Announces New Scientific Data, Educational Events at the American Society of Cataract and Refractive Surgery Annual Meeting
Bausch + Lomb announced it will present 45 scientific papers and posters at the American Society of Cataract and Refractive Surgery (ASCRS) annual meeting in Washington, D.C., from April 9‑13, 2026. The sessions will feature data on its ELIOS minimally‑invasive...
African Patients and Trialists Largely Left Out of CV Research
A new study reveals that African populations are dramatically underrepresented in cardiovascular clinical trials, with less than 4 % of 2,472 randomized controlled trials (RCTs) conducted exclusively in Africa and only 0.6 % appearing in top cardiology journals. Lead author Bamba Gaye...
5 Warning Signs of a Skull Fracture That May Turn Fatal
Skull fractures can become fatal if five key warning signs are missed: loss of consciousness, unequal pupils, worsening headache, fluid leaking from the nose or ears, and seizures. These symptoms indicate brain injury, bleeding, or increased intracranial pressure and require...
STAT+: Pharmalittle: We’re Reading About an FDA Delay Forcing a Biotech to Close, a Neurocrine Deal, and More
In February, Kezar Life Sciences secured an FDA agreement for a clinical trial on autoimmune hepatitis, but the meeting was cancelled four months late, prompting the biotech to begin winding down. Meanwhile, U.S. physicians are increasingly prescribing oral GLP‑1 weight‑loss...
Hypercortisolism Common in Patients with Resistant Hypertension
The MOMENTUM study of 1,086 patients with resistant hypertension found that 27.3% had endogenous hypercortisolism. Nearly a quarter of those positive cases displayed adrenal nodules, and 21.5% also had primary hyperaldosteronism, with 5.9% harboring both disorders. Hypercortisolism was associated with...
Key Takeaways From AACE’s 2026 Type 2 Diabetes Algorithm
American Association of Clinical Endocrinology (AACE) released its 2026 consensus algorithm for managing adult type 2 diabetes, the first revision since 2023. The update introduces a diagnostic classification chart to confirm type 2 diabetes and adds metabolic dysfunction‑associated steatotic liver disease (MASLD)...
Rethinking eCOA: Why Earlier Input by Data Managers Is Needed
Electronic clinical outcome assessment (eCOA) is a mature technology, yet its adoption lags behind other digital trial tools. The traditional siloed approach forces data managers to engage only after data collection, inflating costs and extending timelines. Involving data managers early...
Engineered Antibodies Pry Apart The Most Difficult Viruses
Researchers have engineered a bifunctional antibody fragment that simultaneously blocks Marburg virus attachment and neutralizes the exposed receptor‑binding site after the virus undergoes its conformational change. By mimicking the host cell receptor, the antibody tightly binds the viral protein, shutting...
Democratizing Innovation with Agentic AI
Microsoft’s new low‑code AI platform lets healthcare staff build custom agents without programming expertise, enabling rapid solutions for clinical and back‑office challenges. By offering drag‑and‑drop interfaces and pre‑built connectors to electronic health records and billing systems, the tool democratizes agentic...
Neurocrine to Acquire Prader-Will Drug in $2.9B Soleno Buyout
Neurocrine Biosciences agreed to acquire Soleno Therapeutics for $2.9 billion, securing the rare‑disease drug Vykat XR. Vykat generated $190 million in 2025 sales, including $92 million in the fourth quarter, but recent safety concerns and a slowdown in new patient starts have clouded its...
CuraTeQ Biologics Gets ‘Positive’ Results in Phase Study of Omalizumab
CuraTeQ Biologics, a subsidiary of Aurobindo Pharma, announced positive top‑line results from its Phase 3 trial of BP11, a biosimilar to omalizumab (Xolair). The study enrolled 608 patients across 80 sites in seven European countries and India, meeting all primary endpoints...
Ghent, Porto, Wroclaw: Future European HealthTech and MedTech Hubs
The European MedTech sector is entering a phase of industrial maturity, with the global market projected to grow from $549.5 billion in 2025 to $853.4 billion by 2035 at a 4.5% CAGR. Investment is concentrating in three emerging hubs—Ghent, Porto, and Wroclaw—each...
WELL Health Partners with AliveCor for Cardiac Monitoring in Canada
WELL Health announced a partnership with AliveCor to bring the Kardia mobile ECG platform to Canadian patients. The collaboration enables remote cardiac monitoring and real‑time cardiologist review through WELL Health’s telehealth network. By integrating AliveCor’s FDA‑cleared devices, the service aims...
How Multidisciplinary Care and Smarter Tools Can Transform MS Management: Steven Kheloussi, PharmD
Steven Kheloussi, PharmD, argues that smarter clinical decision‑support tools and multidisciplinary teams are essential for effective multiple sclerosis (MS) management. He highlights how integrated EHR‑embedded tools can consolidate relapse history, MRI data, and patient preferences to guide personalized therapy, while...
Complex Cataracts: Choosing the Right Fixation Technique
The article reviews current intraocular lens (IOL) fixation methods for complex cataract surgery, focusing on scleral‑sutured, Yamane‑type sutureless intrascleral, iris‑claw, and piggyback lenses. It highlights the Yamane technique’s advantages in reducing inflammation, eliminating suture‑related complications, and delivering stable centration. Iris‑claw...
When Algorithms Decide Visibility: Ben Beckley, CEO of RevHealth on the Future of Pharma
Ben Beckley, CEO of RevHealth, warns that AI is now the primary gateway to pharmaceutical information, turning search into zero‑click answer delivery. Pharma must move from traditional content publishing to engineering discoverability with machine‑readable, citation‑dense data that AI can surface...
From Data Ownership to Learning Velocity in Direct-to-Consumer Healthcare
Healthcare brands are shifting toward direct‑to‑consumer (DTC) engagement, expanding patient portals and digital front doors. Traditional commercialization stacks—data providers, manual intelligence, and media execution—remain siloed, limiting how quickly insights can be applied. While enterprises build internal data lakes and proprietary...
Complex Careers May Cut Dementia Risk More Than Education
Getting an education is important for a lot of reasons, but there might be one reason you haven’t heard — it could lower your risk of dementia later in life. Decades of research have supported this claim, with one study...
From Noncovalent Fragment to (Non)covalent Leads Against PLPro
Researchers at Vanderbilt have leveraged a protein‑observed NMR fragment screen to revive interest in SARS‑CoV‑2 papain‑like protease (PLPro), an essential viral enzyme with few existing inhibitors. From 13,824 fragments, 77 hits were confirmed, leading to a non‑covalent series that progressed...
Not All Hospitals Have Equal Resources — Knowledge Sharing Can Help Level the Playing Field
Rural and children’s hospitals in the United States face severe financial strain, with 45% operating at a loss and more than 300 at risk of closing. The Centers for Medicare & Medicaid Services has launched the Rural Health Transformation program,...
STAT+: Stealth Biotech Stipple Bets on Secretive ADCs
Stealth biotech Stipple is quietly advancing secretive antibody‑drug conjugates (ADCs) as the market races toward targeted cancer therapies. A recent four‑month FDA review delay forced a cash‑strapped small biotech to shut down, underscoring the existential risk of regulatory setbacks for...
Quemliclustat
Quemliclustat (AB680) is a highly potent (5 pM) selective CD73 inhibitor that completed a Phase I trial in healthy volunteers, demonstrating a pharmacokinetic profile suitable for biweekly intravenous dosing. Early clinical data showed promising activity, prompting a successful Phase II study in pancreatic...
Advisors Should Keep an Eye on Healthcare Sector Amid Stronger-than-Expected Jobs Numbers
U.S. non‑farm payrolls rose by 178,000 in March, far exceeding expectations, while the unemployment rate held at 4.3%. The healthcare sector drove much of the gain, adding 76,000 jobs, with ambulatory services and physicians’ offices leading the surge. Healthcare stocks...
Pharma’s Silent Operational Killer: Lifecycle Change Management
Pharmaceutical companies face a hidden operational crisis: managing thousands of post‑approval changes across hundreds of markets using outdated, spreadsheet‑based processes. A typical large firm evaluates about 6,000 changes annually, generating roughly 90,000 country‑level regulatory filings that can take three to...
FDA Grants IND and Fast Track for Cartography Bio’s T‑Cell Engager CBI‑1214 in Colorectal Cancer
Cartography Bio secured FDA approval of an investigational new drug application and fast‑track designation for its T‑cell engager CBI‑1214, aimed at colorectal cancer. The clearance lets the company launch a Phase 1 study, marking a milestone for cellular immunotherapy in a...
How a Hidden Genetic Mutation Creates a Severe Pediatric Anesthesia Risk
A rare mitochondrial DNA point mutation (mtND4 m.11232T>C) has been linked to catastrophic neurologic injury in children exposed to the volatile anesthetic sevoflurane. The mutation, maternally inherited and prevalent among people of Venezuelan ancestry, was identified after decades of isolated...
Workers’ Comp Provider Networks Cut Total Claim Costs by 26%, Drive Faster Access to Care
A Workers’ Compensation Research Institute study of over seven thousand lost‑time claims across 34 states finds that provider networks lower total claim costs by 26%, saving roughly $11,820 per claim at 36 months. Medical payments drop 27%, about $3,500 per...
Strategies for Hospices Supporting Family Caregivers
Family caregiving in the United States has surged to 63 million adults, a 45% increase since 2015, placing unprecedented strain on hospice providers. End‑of‑life caregivers average 20 hours of support per week, juggling medical, logistical, and emotional duties. Hospices are responding by...
Optimal Sleep for Insulin Resistance: 7 Hours 18 Minutes
As a medical school professor, I teach that sleep matters for metabolism. But now we have the precise number. A study of 23,475 adults published in BMJ Open Diabetes Research & Care found the optimal sleep duration for preventing insulin resistance:...
Centene Latest Health Insurer To Shakeup Management Ranks
Centene announced creation of two senior executive roles, naming Daniel Finke as group president of markets and commercial and Michael Carson as group president of Medicare and specialty. The moves come as the insurer grapples with a $1 billion fourth‑quarter loss...
Aging Gut Loses Magnesium, Boosting Inflammation Risk
As a medical school professor, I never imagined a single mineral could be this important to gut health. But the data is staggering. A new study in Aging Cell found that magnesium levels decline specifically in the gut as we age...
Media Networks Sydney Pty Limited - 687044 - 09/18/2024
The U.S. Food and Drug Administration issued a closeout letter to Media Networks Sydney Pty Ltd confirming that the company has discontinued its U.S. listings for Mylanta 2go Antacid Double Strength and Microlax Enema after corrective actions. The agency noted that...
Non‑Drug Therapies Beat Pills for Back Pain
Better than drugs and injections for low back pain: -Exercise -Physical Therapy -Chiropractic -Acupuncture -Yoga -Tai Chi -Cognitive Behavior Therapy Prioritizing your MENTAL and PHYSICAL health is the best form of medicine.
The Dangerous Trap of “One-Drug Cancer Cures”
Recent commentary warns against the allure of one‑drug cancer cures, arguing that such reductionist approaches echo past failures in oncology. While repurposed agents like ivermectin and fenbendazole demonstrate laboratory activity, the author cites severe side effects, including a patient death,...
Oncology Revenue Dominated by Few Classes, KRAS Next.
Great tables from Wedbush listing small molecule oncology and hemonc drugs ordered by approval date. I counted ~20 different classes for solid tumors and ~6 for liquid, most revenues are driven by a handful of classes that reached multi...
Wireless Oxygen Implant Powers Engineered Cells Inside Body
What happens when you give engineered cells their own wireless oxygen supply inside a thumb-drive-sized implant? https://spectrum.ieee.org/biologic-drugs-implant-bioelectronics-medicine?share_id=9322774
Novel Approach to Clearing Brain Waste Shows Promise for Alzheimer's
Researchers have identified a novel method to boost the brain’s waste‑disposal system by targeting the DDR2 receptor, a protein previously studied for lung health. In mouse models, blocking DDR2 lowered amyloid‑beta production and enhanced clearance of toxic protein aggregates, leading...
Myeloma Survival Breakthrough: Two Decades After Dalton’s Wish
I remember interviewing Bill Dalton in 2005 about new developments in myeloma and how he wished for new regimens to take OS out beyond 3-4 yrs. Two decades on we've hit jackpot...
AI Can't Replace Human Empathy in Healthcare
The big issue here surely is the lack of true empathy and therapeutic relationship. Care is not just diagnosis and treatment-it involves emotional support, motivation, and reassurance that AI cannot fully replicate. #AI #health #healthcare #aichatbot https://t.co/ImuiD51Vna
MedTech Innovator Radar Forum April 7-9 Levels Up MedTech Industry’s Most Rigorous Evaluation Platform and Leading Accelerator Program
MedTech Innovator is debuting the Radar Forum, a single, invite‑only event held April 7‑9, 2026 in Manhattan Beach that replaces its previous multi‑city road‑tour pitches. The three‑day forum will host roughly 500 attendees, including 300 top experts who will evaluate the top...
FDA Backs Permanent Re‑authorization of Pediatric PRV Program
FDA calls to permanently re-authorize the rare pediatric disease PRV program in Friday's 2027 budget plan -- far cry from the FDA that complained to the GAO about PRVs as distracting from their public health priorities https://t.co/i79F7X1ECw
FDA Delay Shuts Down Small Biotech in Four Months
How a four-month FDA delay forced a small biotech company to close its doors https://t.co/6vMGJM5SjH
Affinia Therapeutics Receives Approval From Health Canada to Initiate the UPBEAT© Trial, a Phase 1/2 Clinical Trial to Investigate AFTX-201...
Affinia Therapeutics has secured Health Canada approval to launch the UPBEAT© Phase 1/2 trial of its gene‑therapy candidate AFTX‑201 for BAG3‑associated dilated cardiomyopathy. The investigational product delivers a full‑length BAG3 transgene via a proprietary low‑dose AAV capsid, aiming for a one‑time...
In OMB’s FY 2027 Proposed Budget, Healthcare Is the Big Loser
The White House Office of Management and Budget’s FY 2027 budget proposal slashes health‑care spending, cutting the Department of Health and Human Services by $15 billion (12% less than FY 2026) and proposing a $911 billion reduction in Medicaid over ten years. At the...
Re: Men Need Fair Information About Screening for Prostate Cancer
A recent letter highlights how the European Randomized Study of Screening for Prostate Cancer’s 23‑year data are being misread. The trial showed one prostate cancer death prevented for every 456 men invited to PSA screening, but the accompanying statistic of...
Neurocrine Will Pay $2.9B for Soleno and Its Prader-Willi Medicine
Neurocrine BioSciences announced a $2.9 billion acquisition of Soleno Therapeutics, paying $53 per share for the rare‑disease specialist. The deal brings Soleno’s late‑stage Prader‑Willi syndrome therapy into Neurocrine’s growing portfolio. Soleno, a profitable company, adds a commercial platform and additional rare‑disease...
Join Us Tomorrow: How Capitol Imaging Is Using AI-Enabled RIS, Scheduling Bots and Smart Staffing Strategies to Take Care of...
Capitol Imaging Services, a 60‑location outpatient imaging network in the Gulf South and Southeast, is piloting an AI‑enabled radiology information system (RIS) to automate front‑office tasks. Partnering with AbbaDox, the group uses an AI voice agent named Abby to parse...