Today's Healthcare Pulse
Allogene Therapeutics CEO David Chang to step down
Allogene Therapeutics announced that chief executive David Chang will leave his role. The news was reported by STAT+ and echoed in a follow‑up piece covering broader pharma updates.
Also developing:
By the numbers: Boston Scientific invests $1.5B for 34% stake in MiRus
Health System CIOs Say EHR Downtime Resilience Requires Organization-Wide Ownership, Rehearsed Plans, and Structured Documentation
The panel explored how health systems can achieve operational resilience during EHR downtime, emphasizing that resilience is an organization‑wide capability rather than just an IT issue. CIOs Chris Akeroy (Lee Health) and Stuart James (Christus Health) highlighted the need for rehearsed, paper‑based and electronic fallback workflows, clear documentation, and cross‑departmental ownership, while Interlace Health CEO Allison Reichenbach stressed that downtime is fundamentally a documentation challenge. The discussion underscored the complexity of modern, automated workflows and the importance of structured e‑forms and training to ensure safe patient care when systems fail.
Pediatrix Expands Maternal Health Services in Tennessee in Partnership with Tennessee Maternal-Fetal Medicine
Pediatrix Medical Group announced a cash acquisition of Tennessee Maternal‑Fetal Medicine, adding four board‑certified MFM physicians and six advanced practice providers to its Nashville operations. The partnership expands Pediatrix’s presence to five Greater Nashville locations, enhancing access to high‑risk obstetric...
If You Got the Whooping Cough Vaccine (Aka, Tdap or Pertussis Vaccine) in NY Between May 20, 2016 and May...
A class-action settlement has been announced for New York residents who received the Tdap (whooping cough) vaccine between May 20 2016 and May 20 2020 after seeing a specific advertisement. Eligible individuals may file a claim to receive a monetary payment funded by GlaxoSmithKline. The...
GetHealthy Launches Script, an AI-Enabled Platform Expanding Practitioner Commerce Beyond Supplements Across Seven Product Categories
GetHealthy unveiled Script, an AI‑enabled clinical scripting platform that lets health practitioners prescribe comprehensive protocols across seven product categories, from supplements to pet health and diagnostic testing. The solution taps a catalog of over 400 vetted brands and integrates with...
Ophthalmologists Can Act as ‘First Responders’ for Stroke
Ophthalmologists are being urged to act as first responders for stroke by promptly referring patients with acute central retinal artery occlusion (CRAO) to stroke centers. CRAO signals a high risk of imminent cerebral stroke, with the first 48 hours being...
'A Dream Come True': Revolutionary AI Smart Glasses Win $1.4 Million ‘Nobel Prize’ to Combat Dementia
CrossSense’s AI‑enabled smart glasses have captured the £1 million (≈$1.4 million) Longitude Prize for dementia, a prize aimed at practical solutions rather than pure research. The device, equipped with the Wispy assistant, offers real‑time visual and auditory cues to help users with...
Beyond Lipid Nanoparticles: How Custom Polymers and AI May Reshape Gene Therapies
Researchers at Helmholtz‑Zentrum Hereon and partners propose a payload‑driven approach to nucleic‑acid delivery, designing polymeric carriers that are chemically tuned to each DNA, RNA or mRNA payload. The strategy contrasts with the one‑size‑fits‑all lipid nanoparticles that dominate current vaccines and...
My Brother Says Lawyers Can Get Him Into a Medicaid Nursing Home, Despite His Many Assets. Is This a Scam?
The Moneyist explains that while Medicaid generally requires applicants to have no more than $2,000 in countable assets, Florida offers several legitimate ways to preserve wealth, such as exempting a primary residence up to $730,000 equity and using “share‑of‑cost” programs....
Physician Burnout: A Poem on the Unseen Weight of Medicine
Physician burnout has surged as clinicians juggle endless charting, constant alerts, and productivity metrics that treat care like a timed transaction. The poem illustrates how administrative overload erodes compassion, turning the oath of service into a feeling of drowning. Surveys...
HHS Announces Members of Healthcare Advisory Committee
The U.S. Department of Health and Human Services and the Centers for Medicare & Medicaid Services announced the formation of a new Healthcare Advisory Committee. The panel, chaired by Bill Gassen of Sanford Health, includes Dennis Laraway of Cleveland Clinic...
AHA: Anthem Facility Administrative Policy Sets Providers up to Fail
The American Hospital Association (AHA) warns that Anthem’s new facility administrative policy forces hospitals in 12 states to guarantee every physician treating an Anthem enrollee is in‑network. Non‑compliance could cut hospital reimbursements by roughly 10% or result in removal from...
Study: Premature Placental Separation Could Increase Child’s Risk of Heart Disease by Age 28
An American Heart Association study of nearly three million pregnancies found that children born after placental abruption—affecting about 1 % of U.S. pregnancies—face a significantly higher risk of cardiovascular disease by age 28. The analysis shows almost a three‑fold increase in hospitalizations for...
Chronilogix Announces Dr. Geoffrey Williams’ Appointment to Advisory Committee, Supporting Expansion Into AI-Driven Mental Health Coaching
Chronilogix, an AI-driven digital health firm, announced that Dr. Geoffrey Williams has joined its Advisory Committee as the company launches a new AI-powered mental health coaching module. The addition expands Chronilogix’s portfolio beyond chronic conditions like diabetes and obesity to...
Frank Harrell on Why and How to Do Bayes for Clinical Trials and the Recent FDA Draft Guidelines
Frank Harrell, a former FDA statistician, responded to recent JAMA commentary on the agency’s draft guidance promoting Bayesian methods for clinical trials. He highlighted that while the guidance is a step forward, FDA reviewers still rely on traditional frequentist approaches...
Clinical AI API Enables Easy Evidence‑Based Diagnostics
Evidence-based clinical intelligence is becoming a critical infrastructure for many healthcare technology companies. We've made building with our clinical AI agent exceptionally easy with in-app self-serve access to the Glass Developer API. Developers can get started building with our AI today and...
Blossom Health Secures $20 Million to Launch AI Copilot for Psychiatry
Blossom Health announced a $20 million seed and Series A financing led by Headline, with participation from Village Global, TA Ventures, Operator Partners and Correlation Ventures. The funds will be used to roll out an AI “copilot” that assists psychiatrists with...
FDA Releases 2026 Guidance Overhauling Supplement GMP, Labeling and NDI Rules
The U.S. Food and Drug Administration issued a comprehensive 2026 guidance that updates current Good Manufacturing Practice (cGMP) standards, labeling requirements, and New Dietary Ingredient (NDI) notification procedures for dietary supplement manufacturers. The guidance, detailed in a Qalitex Laboratories briefing,...
Hengrui Posts 13% Revenue Rise and Record $1.1B Net Profit in 2025
Jiangsu Hengrui Medicine announced 2025 results showing a 13% jump in revenue to RMB 31.63 billion ($4.4 billion) and a 21.8% rise in net profit to RMB 7.72 billion ($1.1 billion). The surge was powered by strong innovative‑drug sales and a landmark Hong Kong...
Ophthalmologists Need to Identify Different Types of Ptosis
Ophthalmologists must differentiate among dermatochalasis, blepharoptosis, brow ptosis and mixed forms to select appropriate therapy. Dr. Jennifer Murdock highlighted that accurate diagnosis often requires moving the brow and eyelid to expose the underlying cause, whether traumatic, neurogenic or aponeurotic. Non‑surgical...
Bulk Drug Substances Used in Compounding
The FDA issued guidance clarifying how compounding pharmacies may use bulk drug substances, also known as active pharmaceutical ingredients. Under section 503A, state‑licensed physicians and pharmacists can compound with bulk substances that meet USP/NF monographs, are components of FDA‑approved drugs, or...
AI Simulates Patient Tumors, Transforming Oncology Research
@Ronalfa is speaking at @SynBioBeta in May and you probably already know who he is if you've been paying any attention to the AI x bio space. Ron spent years at @RecursionPharma as SVP of Research and acting CSO, helping build...
Agentic AI, Virtual Cell, LNP Vaccine Boosters, Engineered Organs, and Mergers
In this episode of Touching Base, the Gen editorial team discusses the latest advances in AI for life sciences, including NVIDIA’s GTC announcements on agentic AI, the deployment of 3,500 GPUs by Roche, and the emergence of open‑source autonomous agents...
AI Tool Can Screen Unknown Bacteria for Disease-Linked Genes, Moving Closer to Preventing Pandemics
Researchers at Denmark's DTU unveiled PathogenFinder2, an AI system that screens unknown bacteria for disease‑linked genes using protein language models. Trained on over 21,000 genomes, the tool predicts pathogenic potential even for species with no known relatives and highlights the...
Assessing the Implementation of National Sodium Reduction Policies in Nigeria: An Interim Qualitative Evaluation of Stakeholder Perspectives
Nigeria’s National Multi‑sectoral Action Plan (NMSAP), launched in 2019 to curb dietary sodium, was evaluated three years later through 47 interviews and five focus groups. Stakeholders highlighted emerging nutrient‑profiling tools and school‑based nutrition education as facilitators, but noted critical gaps...
Top 5 Use Cases of Healthcare Strategy Management Software | ClearPoint Strategy Blog
ClearPoint Strategy’s February 2024 blog outlines five core use cases for its strategy‑management platform in hospitals: boosting 5‑star quality ratings, optimizing revenue‑cycle management, supporting value‑based pricing, driving continuous quality improvement, and tracking HEDIS metrics. The post explains how the software integrates...
Pharmaceutical Executive Daily: Trump Administration Misses Deadline to Nominate Permanent CDC Director
The Trump administration failed to meet the 210‑day deadline to nominate a permanent CDC director, leaving the agency without confirmed leadership for most of the second term. Meanwhile, the FDA granted accelerated approval to Denali Therapeutics’ Avlayah, the first enzyme...
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The Link Between Lithium and Weight Gain
Lithium remains a cornerstone mood‑stabilizer for bipolar disorder, but roughly one‑quarter of patients report weight gain, typically 10–26 lb. Recent meta‑analyses show lithium’s impact on weight is modest compared with antipsychotics such as olanzapine or quetiapine, and often comparable to placebo....
Partial Knee Replacement Had Higher Patient Satisfaction vs TKA
A recent analysis of 105 knees shows that partial knee arthroplasty delivers higher patient satisfaction and greater range of motion than total knee arthroplasty, though it carries a higher re‑operation rate. The cohort included 56 partial and 49 total procedures...
New AI Platform Uncovers Hidden Cancer Targets, Raises $10M
Most cancer drugs go after the same targets: EGFR. PD-L1. HER2. Not because they’re the best targets. Because they’re the only ones we’ve been able to see. RyboDyn Inc. is going after what’s been invisible. The San Diego team, led by Imad Ajjawi, PhD,...
Insights on FDA, AI, and Misinformation with Rob Califf
What a joy to chat with my old friend Rob Califf @DrCaliff_FDA about the FDA under his leadership, the FDA today, AI regulation, misinformation, clinical research & more. We also discussed his memories of being a @UCSF medicine resident back...
Let Cuba Live
The author’s visit to Havana highlights how the U.S. embargo fuels dire shortages in Cuban hospitals, exemplified by premature twins battling formula scarcity. The piece also underscores Cuba’s deep Black cultural roots, with public reverence for African heritage and a...
AI Smart Glasses Secure Funding for Dementia Care, Efficacy Unclear
AI smart glasses win major funding to support dementia care, though real-world effectiveness and long-term impact remain uncertain despite early promising observations. https://t.co/vX7jBV2aJt
Hospitals Must Ask: Will Clinicians Actually Use AI?
What should hospitals consider before adopting a new AI tool? Start simple: will people actually use it? That’s a key takeaway from our panel at #vMed26: “Translating AI Findings into Real-World Clinical Impact.” https://t.co/dTZgscHIOM
How Medicare’s MIPS Impacts Skilled Nursing Facilities and Clinicians
Medicare’s Merit‑based Incentive Payment System (MIPS) now directly ties skilled‑nursing facility (SNF) documentation to clinicians’ reimbursement, with adjustments of up to ±9% of Part B payments. As CMS rolls out MIPS Value Pathways, data from SNFs—vaccinations, screenings, care transitions—feed the clinician’s...
Low‑cost, Patent‑free Vaccines Have Helped 100 Million
A “kazarian?” Is that like a Kardashian? What planet are these X trolls from? I develop low-cost often patent-free vaccines for global health and to help humanity. So far 100 million have benefited from access to our vaccine technologies developed...
Current Evidence on NAD⁺ Supplements Remains Inconclusive.
NAD⁺ supplementation for anti-aging and wellness: a PRISMA-guided systematic review of preclinical and clinical evidence https://t.co/au5YIC11Hw https://t.co/fMsAOSQF6f
The Natural “Biological Clock” Of Stroke Recovery
The ESPRESSO trial tested whether adding 90 minutes of high‑intensity hand and arm therapy each day for the first two weeks after stroke improves recovery. Sixty‑four participants received either immersive video‑game‑based or conventional therapy alongside standard care, but three‑month outcomes...
Welldoc® Honored with 2026 Artificial Intelligence Excellence Award
Welldoc® received the 2026 Artificial Intelligence Excellence Award from the Business Intelligence Group, marking its third consecutive win in the Health Product category. The award highlights Welldoc’s responsible, outcomes‑driven AI that combines clinical precision with regulatory compliance. The company’s platform...
259: Dr. Matt Bernstein, Metabolic Psychiatrist: Your Sleep & Mental Health Problems Might Start With Food
In this episode, host Molly Eastman talks with Dr. Matt Bernstein, a psychiatrist and CEO of Accord, about metabolic psychiatry and how diet—particularly ketogenic nutrition—affects mental health, anxiety, and sleep. Dr. Bernstein explains the science behind ketosis, its impact on...
Some Antiseizure Medications May Be Safer than Others During Pregnancy
Researchers analyzing U.S. insurance claims from 2000‑2021 found that prenatal exposure to valproate and possibly zonisamide increased the risk of neurodevelopmental disorders in offspring, while levetiracetam, lamotrigine, and phenytoin showed no such associations. The study evaluated 14,993 pregnancies exposed to...
Doctor Cleared, Nurses Detained as Injection Error Kills Two Sisters
A medical panel cleared the prescribing doctor after a fatal medication error killed two young sisters at Zuru General Hospital, while two nurses remain in police custody. The children, aged six and three, received the wrong injection on March 18,...
Senate Rejects Proposal to Overturn VA’s Abortion Ban
The Department of Veterans Affairs reinstated a near‑total abortion ban, limiting procedures to life‑threatening emergencies. A Senate vote of 50‑48 rejected Sen. Richard Blumenthal's amendment to overturn the ban, keeping the restriction in place. The 2022 policy that allowed abortions...
March 2026 Dispatch for the CV Team
The March 2026 CV Dispatch highlights a range of new findings, from a Chinese cohort linking elevated blood pressure at embryo transfer to lower live‑birth rates, to the PROMISE trial showing women experience similar major cardiovascular events despite lower plaque...
AI Could Improve Accuracy of PD-L1 Scoring for NSCLC
AI algorithms scored PD‑L1 expression in non‑small cell lung cancer with accuracy comparable to, and in some cases exceeding, manual pathologist assessment, especially for the SP142 assay. The study analyzed 80 slides from the Blueprint project against consensus scores from...
Biopharma Industry Pushes Back on FDA's 'America First' User Fee Proposals
The FDA’s upcoming user‑fee framework, dubbed "America First," seeks to tighten eligibility for the small‑business waiver, limiting it to U.S.‑based applicants. Industry groups argue the change politicizes fee policy and could disadvantage foreign‑owned biotech firms that rely on the waiver...
The Scoreboard on Biden’s Vaccine Purge: 8,000 Kicked Out. One by One, They’re Coming Back.
The Biden administration’s COVID‑19 vaccine mandate led to the discharge of nearly 8,000 service members across all branches. Federal courts have ruled the mandate’s implementation unlawful, prompting a wave of reinstatements. The Air Force has cleared the records of roughly...
BREAKING: UK Government Releases New “PANDEMIC PLAN”
The UK government unveiled a new “All Pandemics Hazard Bill” as part of a £1 billion (≈$1.25 billion) pandemic preparedness plan. The strategy adds an AI‑driven contact‑tracing system slated for 2030, a £250 million (≈$312.5 million) biosecurity hub in Harlow expected to be operational...
Attention Failures May Predict Dementia Better Than Memory
Researchers at Swansea University argue that attention impairment, not memory loss, is the earliest detectable sign of dementia. Their new book presents the "Attention First" theory, showing that deficits in filtering and sustaining focus can precede measurable memory decline across...
TACC Launches CFDE Cloud Workspace for NIH Common Fund Datasets
The Texas Advanced Computing Center (TACC) has publicly launched the Common Fund Data Ecosystem (CFDE) Cloud Workspace, a collaborative effort with Johns Hopkins, Penn State and the San Diego Supercomputer Center’s CloudBank. The platform gives researchers instant, no‑cost access to...
How to Build Trust and Retention in Patient Support Programs
Patient support programs (PSPs) are growing alongside specialty drugs, but manufacturers often miss early warning signs of disengagement. Tina Valbh highlights patient abandonment—unanswered calls and missed follow‑ups—as a primary indicator that a program isn’t meeting needs. She argues that many...