Today's Healthcare Pulse
FDA greenlights four new oncology products, including AstraZeneca’s Truqap
The FDA approved four oncology products in mid‑June 2026: AstraZeneca’s AKT inhibitor Truqap for PTEN‑deficient metastatic prostate cancer, Roche’s VENTANA PTEN companion diagnostic, Bayer’s low‑dose MRI contrast agent Ambelvist, and MSD’s Keytruda‑Welireg combo for high‑risk renal cell carcinoma. Truqap demonstrated a 19% reduction in disease‑progression risk and added 7.5 months of progression‑free survival. The approvals were reported by Pharmaceutical Technology and PharmaShots.
Also developing:
Veradigm Cut 15% of Its Workforce in 2025
Veradigm announced a 15% workforce reduction in 2025, closed three offices and plans two more closures, and will discontinue six low‑revenue products as part of a broader turnaround. The health‑IT firm is also focused on updating its financial filings after a 2024 Nasdaq delisting, aiming to release its 2023 and 2024 reports and seek relisting. Revenue for 2025 is projected between $584 million and $589 million, a modest 1% decline. These moves are intended to streamline operations, restore compliance, and position the company for profitable growth.
Blood P‑tau217 Test Predicts Alzheimer’s Symptoms 20 Years Ahead
Predicting when symptoms of Alzheimer's disease will occur with elevated p-tau217 blood test and a person's age, even 20+ years in advance @NatureMedicine https://t.co/EYaGglBh1H
STAT+: Pharmalittle: We’re Reading About the FDA Pushing OTC Meds, Its New Trial Standards, and Much More
The FDA, under Commissioner Marty Makary, is pushing to expand over‑the‑counter (OTC) availability for safe prescription drugs such as nausea treatments and vaginal estrogen. Simultaneously, the agency proposes dropping the long‑standing requirement for two pivotal clinical trials, moving to a...
How Medplum Secured Their Healthcare Platform with Docker Hardened Images (DHI)
Medplum, an open‑source headless EHR serving over 20 million patients, migrated its production containers to Docker Hardened Images (DHI) with just 54 lines of code changes across five files. The switch replaced custom hardening scripts with Docker’s secure‑by‑default base images, eliminating...
Gossamer Lung Trial and ProMis Alzheimer Therapy Spotlight
This week's Biotech Scorecard newsletter: -- What to expect from $GOSS Gossamer Bio’s late-stage lung disease study -- A better, safer Alzheimer’s treatment? ProMis $PMN takes its shot https://t.co/YaA8kvUR4Z
Profusa Enables Real‑Time Tissue Biochemistry Monitoring
👍Profusa is my pick for 2026. Fascinating technology to measure real time tissue biochemistry. This is a fundamental shift from blood to tissue to shine a new light on cellular status and metabolism. https://t.co/gfduGvgJTX @ProfusaInc #medicine $PFSA #diabetes
4 Ways a Technology-Enabled Medical Center Can Improve Your Weight Loss Journey
Obesity affects over 42% of U.S. adults, prompting a surge in weight‑loss solutions. Technology‑enabled medical centers combine clinical expertise with digital tools to deliver data‑driven, personalized programs. By continuously monitoring biomarkers, body composition and activity, they adapt nutrition and exercise...
Treg Pioneer Bluestone Joins Vie Ventures as It Builds Autoimmune Portfolio
Vie Ventures has hired immunology veteran Jeff Bluestone to strengthen its autoimmune‑focused venture portfolio. Bluestone, founder of the Immune Tolerance Network and former CEO of the Parker Institute for Cancer Immunotherapy, previously co‑founded Sonoma Biotherapeutics and created Tzield teplizumab, the...
LPM-5140276 Shows Enhanced Antitumor Efficacy in Combination with RMC-4550
Researchers reported that the novel KRAS G12D inhibitor LPM-5140276 markedly improves antitumor activity when paired with the SHP2 inhibitor RMC-4550. The combination demonstrated synergistic tumor regression in preclinical models of pancreatic and colorectal cancers harboring KRAS G12D mutations. Data suggest enhanced pathway...
FNIH Biomarkers Consortium Study Shows “Clock Model” Blood Test Can Predict Onset of Alzheimer’s Symptoms Years in Advance
The FNIH Biomarkers Consortium unveiled a “clock model” that uses a single blood test to forecast Alzheimer’s disease symptom onset 3‑4 years before clinical presentation. The model aggregates plasma biomarkers into a temporal trajectory, and a new web‑based visualization tool...
SEQSTER Launches 1-Click Data Refinery™ to Power Scalable AI Across Clinical Trials
SEQSTER PDM, Inc. unveiled its 1-Click Data Refinery™ – an enterprise‑grade engine that converts raw, patient‑consented EHR data into clean, structured, AI‑ready records. The platform normalizes, deduplicates and harmonizes data across health systems, delivering longitudinal patient views suitable for rapid...
Blackbird-Backed Telehealth Startup Eucalyptus Sells for $1.6 Billion to US Listed Rival
Australian telehealth startup Eucalyptus is being acquired by NYSE‑listed Hims & Hers for $1.15 bn, valuing the company at A$1.6 bn. The deal includes an upfront $240 m payment and deferred cash or stock plus earn‑out provisions through 2029. Eucalyptus reports an ARR north...
ViiV Healthcare Reports P-III (LATITUDE) Trial of Cabenuva in Adherence-Challenged HIV Patients
ViiV Healthcare presented results from the Phase III LATITUDE trial evaluating Cabenuva, a long‑acting injectable of cabotegravir and rilpivirine, in 453 adults with adherence challenges. Among 306 virally suppressed participants, the quarterly injection reduced cumulative regimen failure to 22.8% versus...
Radiopharmaceutical Therapy Use Has Increased 2,000% Among Medicare Population
Radiopharmaceutical therapy (RPT) utilization among Medicare beneficiaries surged 2,000% between 2013 and 2023, climbing from 529 to 12,395 IV administrations. The study identified a 37% compound annual growth rate, with diagnostic and interventional radiology delivering 45.2% of services and nuclear...
High Risk Research: HHS Should Publicly Share More Information on How Risk Is Assessed and Mitigated
The Government Accountability Office (GAO) reports that the Department of Health and Human Services (HHS) conducts risk assessments for gain‑of‑function research but does not consistently share those findings with the public. While the research has expanded understanding of pathogen transmission,...
Roland DGA Launches Elevate Denture Solution for Digital Workflows
Roland DGA has introduced the Elevate Denture Solution, a digital denture kit that bundles Ivoclar Ivotion discs, hyperDENT CAM strategies, adapters and PMMA tooling for use with DGSHAPE DWX‑53 series mills. Developed with Ivoclar and FOLLOW‑ME! Technology, the solution offers...
Private Health Insurance: Provider Participation and Payments for Selected Services Before and After the No Surprises Act
The Government Accountability Office examined how the No Surprises Act affected provider participation and payment levels for emergency medicine, radiology, anesthesiology and air‑ambulance services from 2019 through 2023. After the act’s protections took effect on January 1 2022, the share of in‑network...
INSM Projects 2026 Brinsupri Sales Minimum $1B
$INSM guides to 2026 Brinsupri sales of "at least $1B" in line with consensus. https://t.co/o7JhPKU3m1
Who’s the Agent? Building the Identity Layer Healthcare AI Actually Needs
The episode explains that traditional user‑centric identity systems are insufficient for autonomous AI agents in healthcare, which need a dedicated agentic identity layer to manage fine‑grained PHI access, audit trails, and delegation across humans and machines. It highlights the regulatory...
CMS Broadens Drug Price Negotiations to Part B Therapies
The Centers for Medicare & Medicaid Services announced a third round of drug price negotiations that for the first time includes Part B physician‑administered therapies. By extending the Inflation Reduction Act’s pricing provisions to infused medicines, the move pulls doctors into...
FDA Clearance Sets Stage for U.S. Commercialisation of Eyonis LCS
Median Technologies has named veteran imaging executive Oran Muduroglu as President of its U.S. subsidiary, Median eyonis Inc., to spearhead the commercial launch of eyonis LCS, an AI‑powered lung‑cancer‑screening SaMD that recently received FDA 510(k) clearance. The rollout will leverage a defined Medicare reimbursement...
Oral Nanozyme Treats Colitis-Linked Mental Disorders via Gut-Brain Axis
Researchers at Yangzhou and Nanjing Universities have created an oral polysaccharide‑engineered nanozyme—fucoidan‑cerium nanocomplexes (FucCeNCs)—to treat colitis‑associated anxiety and depression. The nanocomplex combines cerium’s superoxide dismutase‑like activity with fucoidan’s prebiotic properties, enabling simultaneous reactive oxygen/nitrogen species scavenging and gut microbiota modulation....
CRISPR Therapeutics Gains After Earnings as Pipeline Hope Grows
CRISPR Therapeutics shares rose over 12% after reporting Q4 2025 earnings that showed a larger‑than‑expected loss and minimal recognized revenue. The company’s flagship therapy CASGEVY generated $54 million in sales, but under its revenue‑sharing deal with Vertex only $0.86 million was recorded. CRISPR...
Take Two: EP398: Why Are Commercial Carrier Marketplaces Completely Boring? Maybe Because There Isn't a Marketplace, With Jacob Asher, MD
In this episode of the "No Market" series, host Stacey Richter talks with Dr. Jacob Asher, a former chief medical officer for major health plans, about why commercial carrier marketplaces—especially in California—are stagnant and lack true competition. They identify six...
STAT+: What to Expect From Gossamer Bio’s Late-Stage Lung Disease Study
Gossamer Bio is set to announce results from its Phase 3 trial in pulmonary arterial hypertension (PAH) before the end of February. The readout follows a Phase 2 study that delivered modest, sub‑par efficacy, which the company attributes to an...
DHL Expands Airfreight Cold Chain Network
DHL Group is expanding its dedicated air‑freight cold‑chain network, adding more than 30 GDP‑compliant aviation hubs and a new Brussels‑Cincinnati corridor. The rollout is part of a €2 bn investment in DHL Health Logistics and includes a dedicated Boeing 777 freighter painted...
Partial Reprogramming of Neurons Encoding Memory Improves Cognitive Function in Aged Mice
Researchers applied cyclic OSK (Oct4‑Sox2‑Klf4) gene therapy to memory‑encoding neurons in aged mice, achieving partial cellular reprogramming without full pluripotency. The intervention reversed senescence‑related gene expression, restored youthful epigenetic patterns, and normalized synaptic plasticity in both hippocampal and prefrontal engrams....
Anthropic: It’s “Critical” To Bring Company Products to EHR
Anthropic is pushing its Claude AI model into electronic health record (EHR) systems, arguing that integration is essential for real‑time clinical value. The company highlighted a roster of 25 healthcare partners, including Abridge, Novo Nordisk, Genmab and Banner Health, to showcase both...
Pharma Pulse: FDA’s Moderna Reversal and Eli Lilly’s $100 Million IL-6 Bet
The FDA has reversed its earlier refusal-to-file and will review Moderna’s seasonal mRNA influenza vaccine, with a decision slated for August 5, 2026. Moderna now seeks full approval for adults aged 50‑64 and accelerated approval for those 65 and older. Meanwhile, Eli Lilly...
Scotland’s First Photon-Counting CT Scanner Set to Advance Multi-Organ Research and Enhance Patient Diagnosis & Care
The University of Edinburgh has installed Scotland’s first photon‑counting CT scanner, the Siemens Healthineers NAEOTOM Alpha, funded jointly with the British Heart Foundation. This technology captures each X‑ray photon, delivering ultra‑high‑resolution, spectral images that surpass conventional CT capabilities. It will...
Prevention Is Turning a Corner as Public Demand Surges – but NHS Digital Infrastructure Is Still Lagging Behind
Public demand for preventative health in the UK is surging, with NHS App registrations now at 33.6 million – roughly twice the nation’s Netflix subscriber base. A PA Consulting survey shows eight‑in‑ten NHS leaders believe digital tools can cut health inequalities,...
Antioxidant Nanoparticles May Protect Male Fertility During Chemotherapy
A preclinical study published in Reproductive and Developmental Medicine found that combining melatonin with zinc oxide nanoparticles mitigates cyclophosphamide‑induced reproductive toxicity in male rats. The antioxidant duo restored testosterone and luteinizing hormone levels, lowered oxidative stress markers, and preserved spermatogenic...
Nevada Debuts Public Option Amid Tumultuous Federal Changes to Health Care
Nevada launched its Battle Born public option health plans last fall, aiming to lower premiums and expand coverage. Early enrollment reached just over 10,000 members, far short of the 35,000 target set by state officials. The program must cut premiums...
MSD and Mayo Clinic Team up to Advance AI in Drug Development
Merck (MSD) and Mayo Clinic have launched a research partnership that blends Mayo's Platform architecture and multimodal clinical‑genomic data with MSD's virtual‑cell technologies. The collaboration gives MSD direct access to de‑identified imaging, lab, molecular and notes data to train and...
Alira Health Sued for Stock Manipulation and Fraud
Alira Health and its CEO Gabriele Brambilla face multiple lawsuits from startup founders alleging fraud, unjust enrichment, and violations of the Securities Exchange Act. The plaintiffs claim Alira used inflated stock to acquire companies, set unattainable performance targets, and then...
Opinion: My Biggest GLP-1 Ethical Problem: Patients Who Don’t Want to Stop
GLP‑1 agonists have moved from scarcity to abundance, reshaping weight‑management practice. In 2023, shortages forced clinicians to ration these drugs, often off‑label for obesity. Today, the surplus creates a new dilemma: patients seeking extreme, unsustainable weight loss and refusing to...
Verily Launches Self-Serve Access to Pre Platform with New Segmed and RefinedScience Datasets
Alphabet’s Verily has introduced a free, self‑serve Standard tier for its Pre precision‑health platform, allowing researchers to access the Exchange catalog and Workbench environment with just a Google account. The rollout adds three high‑impact datasets: a single‑cell AML cohort from...
Stratasys Introduces Multi-Material 3D Printed Anatomical Model Preset for Dental Training
Stratasys has launched a multi‑material 3D‑printed dental anatomical model preset using its PolyJet technology, enabling realistic, customizable training devices. The preset defines material ratios and distribution patterns to consistently mimic bone, teeth, nerves, and soft tissue. Models can be personalized...
Gold@MnFe‐Prussian Blue Analog Yolk@Shell Nanoparticles for Light‐Triggered and pH‐Sensitive Drug Release
Researchers have engineered Au@MnFe‑Prussian Blue Analog yolk‑shell nanoparticles that combine a hollow cavity with a functional shell for biomedical use. The synthesis creates a ~75 nm interior, achieving roughly 50% loading efficiency for the chemotherapeutic doxorubicin. Partial etching and redeposition of...
Achieving High‐Efficiency Type I Multimodal Photosensitizers via a Synergistic Rigidity‐Flexibility Strategy for Hypoxia‐Resistant Tumor Therapy
Researchers introduced a donor‑acceptor (D‑A) molecular design that couples a rigid coplanar backbone with flexible side chains, dramatically raising near‑infrared molar extinction and fluorescence brightness. The resulting phenothiazine‑based photosensitizer, EL‑TPO2F, also exhibits strong type‑I reactive oxygen species (ROS) production and...
Hana Health by DSS Imagetech Partners with Overture Life to Bring World-First Automated Egg-Freezing Technology to India
Hana Health by DSS Imagetech has signed an exclusive agreement with Overture Life to launch DaVitri, the world’s first automated egg‑freezing platform, in India. The system standardises the vitrification step of IVF, cutting variability and enabling clinics to handle more...
Swedish CubaseBio Emerges From Stealth with €5.9 Million to Scale Volumetric DNA Microscopy
Swedish startup CubaseBio has emerged from stealth after raising €5.9 million in blended financing – a €2 million European Innovation Council grant plus €3.9 million from Voima Ventures, Nordic Science Investments, Illumina Ventures and other life‑science investors. The capital will accelerate development of...
Hampshire Hospitals NHS Foundation Trust Boosts Imaging Productivity and Resilience Following Major CT Upgrade
Hampshire Hospitals NHS Foundation Trust has completed a major CT upgrade, standardising imaging across Basingstoke, Winchester and Andover with a unified fleet of Canon Aquilion ONE/PRISM and Aquilion Prime SP scanners. The project introduced a dedicated cold‑site CT in Basingstoke,...
9 Companies Hiring Now in Pennsylvania
Pennsylvania’s Greater Philadelphia corridor remains a biotech hotbed, housing over 1,200 life‑science firms including AstraZeneca, GSK and Johnson & Johnson. Eli Lilly announced a new injectable weight‑loss manufacturing plant in the Lehigh Valley, projected to create roughly 850 jobs by 2031....
Lancashire and South Cumbria NHS Chooses EBO’s Patient Portal
Lancashire and South Cumbria NHS Foundation Trust is rolling out EBO’s Intelligent Patient Portal (IPP) as part of its digital transformation, offering a conversational AI interface that guides patients through appointment management and care tasks. The portal is built on...
ElliQ Robot Tackles Loneliness, Featured in NYT
“A robot with soul” ElliQ from @intuitionrobo can help address loneliness & isolation in the @nytimes https://t.co/ydLLNCwnHS
NHS Transformation Directorate Launches Best Practice and Content Guidance for Patient Messaging
The NHS Transformation Directorate has issued best‑practice and content guidance to help NHS staff decide when and how to message patients via NHS Notify, the NHS App, text, email or letters. The guidance combines clinical safety, governance and digital best...
Elsevier ClinicalKey AI Adds NEJM, The Lancet, and HIPAA Compliance
Elsevier has upgraded its ClinicalKey AI platform by adding full‑text access to more than 130 top‑tier medical journals, including NEJM and The Lancet, and by integrating clinical guidelines from leading societies. The new version introduces real‑time traceability, linking AI‑generated answers...
Big Food Pours Millions Into Rebrands as Obesity Drugs Reshape US Demand
US food and beverage giants are accelerating rebranding and product reformulation as GLP‑1 obesity drugs reshape consumer demand. Appetite‑suppressing medications are projected to erase up to $12 billion in snack sales over the next decade, prompting companies like PepsiCo, Coca‑Cola and...
Master Bond Debuts UV26DCMed Dual-Cure Adhesive
Master Bond introduced UV26DCMed, a single‑component, dual‑cure adhesive for medical device assembly that combines UV light for rapid fixturing with a heat bake for full polymerization. The formulation tolerates repeated sterilization methods—including steam autoclave, ethylene oxide, glutaraldehyde, and hydrogen‑peroxide—while meeting...