
DEA Fine Tunes Power of Attorney and DEA-222 Requirements
On March 20, 2026, the DEA issued a technical amendment to its 2019 final rule that clarifies who may execute and revoke Power of Attorney documents for DEA Form 222 and who may sign the form itself. The amendment aligns 21 C.F.R. § 1305.05(c) and § 1305.05(e) with the earlier requirement that only the registrant, an officer, or a partnership partner can authorize POAs, eliminating the previous loophole allowing the last registration applicant to sign. It also removes the obsolete transition provision for triplicate DEA‑222 forms, which had been phased out in 2021. The rule takes effect immediately.

How Spinal Cord Stimulation Offers Relief for Chronic Pain
Spinal cord stimulation (SCS) is gaining traction as a minimally invasive solution for patients whose chronic pain persists despite medication, physical therapy, or injections. A 2026 systematic review of 15 randomized trials involving 1,479 participants showed pain reductions of 2.4...
Fluorescent Microneedle Biosensors Turn Skin Biochemistry Into Scannable QR Codes
The article reports a new biodegradable microneedle patch that uses binary fluorescent probes to turn interstitial pH and glucose levels into a scannable QR code. Each of the 25 needles acts as an on/off switch at a predefined concentration, eliminating...

What March 2026 Is Telling Us About Healthcare’s Next Era
UnitedHealth Group projects its first revenue decline in a decade, forecasting 2026 revenue above $439 billion while its stock has fallen about 45% over the past year. The company filed a shelf registration to raise debt and equity, sparking concerns about...
It’s March Madness for Hospitals
U.S. hospitals, responsible for 31% of health spending, are confronting a convergence of financial, regulatory, and operational pressures. Medicaid reimbursement cuts, rising labor and drug costs, and higher capital expenses are eroding margins, especially for rural providers. At the same...

Managing Acute Heart Failure: Evidence From the DOSE Trial
The DOSE trial compared low‑dose versus high‑dose IV furosemide and bolus versus continuous infusion in 308 stable acute‑on‑chronic heart‑failure patients. High‑dose therapy (≈2.5 × oral dose) increased the proportion switching to oral diuretics by 48 hours without worsening 60‑day outcomes, while renal...

Now Is the Time for Detransition Diagnosis Codes
Dr. Kurt Miceli of Do No Harm urged the creation of specific ICD‑10‑CM diagnosis codes for detransition at the Detrans Awareness Day conference. The CDC’s ICD‑10 Coordination and Maintenance Committee has approved a remission code, F64.A, slated for October 2026, and...

The $2.3B Wake-Up Call: What GE HealthCare’s Intelerad Deal Actually Means for Imaging IT
GE HealthCare completed a $2.3 billion all‑cash acquisition of Intelerad, the largest recent enterprise‑imaging deal. The platform serves 1,500 health systems, processes 230 million exams annually and generates roughly $270 million in recurring revenue. The transaction underscores a strategic shift from hardware‑centric OEM...

Cultural Humility in Medicine: Why Respect Matters as Much as Science
Cultural humility is emerging as a core competency in modern medicine, urging clinicians to value patients' cultural, spiritual, and socioeconomic contexts alongside clinical science. By actively listening and integrating safe traditional practices, providers build trust that improves adherence and outcomes....

Severe COVID‑19 Pneumonia May Reprogram the Lung for Future Cancer
A new Cell paper demonstrates that severe SARS‑CoV‑2 or influenza pneumonia can reprogram the lung microenvironment, fostering accelerated lung cancer development. The authors attribute this effect to persistent immune activation and epigenetic alterations driven by the viral spike protein, which...

Lean Healthcare Study Tour in Japan: September 2026
Mark Graban is leading a twelve‑person, one‑week Lean Healthcare Study Tour in Japan this September, visiting three hospitals, a medical‑device maker, and a Toyota‑trained factory. The itinerary blends site visits with daily reflection sessions, a TPS‑style improvement simulation, and a...

Gain-of-Function at the Manchester Meningococcal Reference Unit?
A virulent meningococcal outbreak in Canterbury, England, has been traced to a nightclub and a secondary party, raising questions about drug‑related transmission vectors such as cocaine snorted through shared straws. The post highlights the presence of levamisole‑adulterated cocaine, which can...

Dose as the Ultimate MPO Endpoint
Tristan Maurer’s Flash Talk framed dose as the definitive multiparametric optimization (MPO) endpoint for small‑molecule drug design. He argued that dose integrates exposure, pharmacology, and mechanism‑driven effects, making it the linchpin for balancing potency, ADME, and safety. The presentation highlighted...

A Resident’s First Surgery: When the Patient Teaches the Doctor
Kaylan Baban, an internal‑medicine physician, recounts his first solo enucleation as a senior resident, performed on a trauma patient who survived a bar‑stool injury. The patient, Mr. Krueger, expressed gratitude and asked the resident whether he had learned anything, turning the...

Saturday Report 3/21/26 — America’s Healthcare Collapse Is Here, and It Was Written Into Law by the GOP
The GOP‑backed "One Big Beautiful Bill" stripped away the latest Affordable Care Act subsidies, sending premiums soaring and leaving millions without health insurance. Simultaneously, the legislation delivered roughly $5 trillion in tax cuts to the ultra‑wealthy, including President Trump and his...
Claimed “100% Sensitivity and Specificity in Differentiating Autistic Individuals From Typically Developing Controls Using Retinal Photographs” . . . Yeah,...
Two recent JAMA Network Open studies report near‑perfect diagnostic performance for autism using retinal photographs and video‑based deep‑learning models. The retinal study claims 100 % sensitivity and specificity across 958 participants, while the video study reports an AUC above 0.99. Critics...

A Purple Public Health: Remembering the Values that Sustain Us
The Purple Public Health Project released a reflective essay linking public‑health practice to small‑l liberalism, emphasizing pluralism, consequentialism, and procedural values. It argues that recent illiberal trends have eroded public trust and that re‑engaging with liberal norms can restore legitimacy....

What World Leaders Can Learn From Diverse Medical Teams
The author, a 26‑year hospitalist, argues that world leaders should emulate the way diverse medical teams collaborated during the COVID‑19 pandemic. He recounts personal friendships with physicians of varied ethnicities, religions, and sexual orientations who united around patient care despite...

The ELU Multiverse Expands
Two new class‑action lawsuits have been filed that closely echo Epic Systems’ earlier litigation tactics, targeting Health Gorilla and its network partners after a massive data breach. The first case, Lott v. Health Gorilla, was lodged by an Illinois plaintiff...

The Controversy over Maintenance of Certification for Grandfathered Physicians
A physician who received a lifetime American Board of Internal Medicine certification in 1983 argues that the Maintenance of Certification (MOC) program adds little value for experienced doctors. He points to decades of continuing medical education, teaching, publishing, and patient...

Cancer Resistance and Interventions to Mitigate Resistance – Part 1
The post outlines how multi‑agent metabolic regimens—using repurposed drugs and nutraceuticals—initially suppress tumors but often trigger adaptive resistance after about two years. Resistance arises from metabolic plasticity, enrichment of cancer‑stem‑cell‑like subpopulations, and rewiring of stress‑signaling pathways. The author proposes press‑pulse,...

Why Medicare Isn’t as Simple as It Looks
Medicare does not enroll automatically for those who delay Social Security, so missing the sign‑up can leave retirees with secondary coverage and surprise bills. At age 65 Medicare becomes the primary payer, pushing other policies into a secondary role. Delaying...

Beyond Standard Protocols: How Translational Science Helps Difficult IVF Cases
Physicians are turning to translational fertility experts to rescue IVF patients with poor egg quality or recurrent embryo failures. By applying a revised ovulation paradigm, clinicians extended stimulation cycles and fine‑tuned hormone dosing, leading to viable embryos and live births...

Navigating Your Orthopedic Surgery Residency After Match Day
Orthopedic surgery remains one of the most competitive specialties, with 916 residency slots across 218 programs and a 74.3% match rate for U.S. allopathic seniors in 2024. Dr. John Klibanoff emphasizes that Match Day marks the start of a broader...

Evidence-Based Medicine Vs. Clinical Judgment: A Medical Student’s Perspective
A third‑year medical student describes how point‑of‑care calculators like MDCalc translate evidence‑based scores into actionable decisions during an emergency medicine clerkship. While these tools improve consistency, the author warns that they can solidify into rigid protocols, turning probabilistic aids into...

The Vaccine Mafia & Religion
The post promotes a recent interview titled “The Vaccine Mafia & Religion” featuring Livio Sanchez of the Vaccine Safety Research Foundation. The conversation, hosted on Rumble, examines how vaccine skepticism is framed through religious language and claims of liability. Readers...
Healthcare Requires a New System Design
Healthcare affordability is reframed as a system‑design challenge rather than a simple pricing issue. The article proposes three interlocking pillars—financial protection, cost discipline through strategic purchasing, and shared digital infrastructure—to achieve universal access without hardship. It cites Thailand’s Universal Coverage...

The Secret Sauce of Leadership Trust in Health Care Teams
The article argues that trust is the "secret sauce" for high‑performing health‑care teams, linking neuroscience to better collaboration, reduced burnout, and superior patient care. It presents Harvard Business School professor Frances Frei’s three‑pillar framework—authenticity, logic, and empathy—as practical levers for...
Health Gorilla and GuardDog Telehealth Set the Record Straight
Health Gorilla released a case study and 21 recorded meetings showing GuardDog consistently described its services as treatment‑focused telehealth. The materials confirm GuardDog’s claim that all data queries were made under HIPAA authorizations to support patient care, not for non‑treatment...

The New Chapter Added to My Vaccine Book
Dr. Gator’s latest update adds a new chapter to *Between a Shot and a Hard Place*, reflecting a year of rapid shifts in U.S. vaccine policy, legal battles, and scientific debate. The chapter details CDC schedule changes that now mirror...

Clinical Reasoning Vs. Documentation: The Next Battleground for Medical LLMs
The first wave of healthcare AI delivered clear ROI by automating clinical documentation, turning high‑entropy encounter notes into structured, billable outputs. Vendors like Nuance DAX, Abridge, and Epic have made ambient scribes a table‑stake feature, driving productivity gains of several...

Three Numbers That Could Prevent the Next Health Emergency
The 7-1-7 framework sets three time‑bound targets—detect an outbreak within seven days, notify authorities within one day, and launch essential response actions within the next seven days. A Lancet Global Health analysis of 41 events in five African nations found...

"Stay Home, Protect the NHS" May Have Cost Lives: Inquiry Stops Short – My Book Exposes the Full Truth
The UK Covid Inquiry’s Module 3 report, released on 19 March 2026, concluded that the "Stay Home, Protect the NHS" slogan likely discouraged people from seeking urgent medical care, contributing to avoidable non‑COVID deaths. The inquiry highlighted a sharp drop in A&E attendances,...

First-of-Its-Kind Implant Could Transform Tissue Loss Treatment
Researchers at Technion’s Levenberg Laboratory have created a first‑of‑its‑kind three‑dimensional implant that merges muscle, fat, a hierarchical blood vessel network and, uniquely, a lymphatic system. The construct is printed with a custom extracellular‑matrix bio‑ink and matured in a flow‑controlled bioreactor....
Vaccines Work. Here’s Why We Care About Your Unvaccinated Child.
The article underscores that measles remains deadly despite overall vaccine success, citing recent tragedies—including a child who died from subacute sclerosing panencephalitis and another who suffered severe encephalitis. It highlights how unvaccinated or under‑vaccinated children, as well as those with...

The 3 Levels of Psychiatric Treatment: Biological, Psychosocial, Moral
The authors propose a three‑level framework for psychiatric care that integrates biological, psychosocial, and moral‑existential interventions. Biological treatment with medication corrects neurochemical disruptions, while psychotherapy addresses social and psychological stressors. The moral‑existential layer, delivered through the therapeutic relationship, fosters meaning,...

Violence Against Health Care Workers: The Silence Must End
The article condemns the growing wave of violence against health‑care workers, underscored by the 2026 murder of nurse Alex Pretti in Minnesota. It blends personal testimony from a retired nurse with a broader call for systemic change, arguing that assaults...
First Surrogate Endpoint in Osteoporosis Clinical Trials with FNIH’s Dr. Tania Kamphaus — Episode 247
On December 2025 the FDA officially qualified dual‑energy X‑ray absorptiometry (DXA) bone density scans as the first surrogate endpoint for fracture outcomes in osteoporosis trials involving post‑menopausal women. The qualification, achieved through a request from the Foundation for the National...

T50.B25x - New ICD-10 Code for COVID-19 Vax Injury Thanks to React19
A new ICD-10 diagnosis code, T50.B25x, has been introduced to capture injuries linked to COVID‑19 vaccinations. The code is not yet reflected on the official ICD‑10 database, suggesting a brief rollout lag. Advocacy group React19 is credited with prompting the...

Is Omitting Data From a COVID-19 Study Conclusion a Lie?
The OpenSAFELY cohort study examined Pfizer vaccination in English children aged 5‑15, finding virtually no COVID‑related deaths and fewer than seven critical‑care admissions during an early‑pandemic window. Vaccine impact was limited to modest, short‑term reductions in infection and a slight...

Aligning Hub Services and Field Reimbursement Teams for Better Patient Support
CoverMyMeds senior manager Kimberly Howard explains that aligning hub services with field reimbursement teams creates a seamless patient‑support workflow. Hubs handle benefit investigations while field reimbursement managers guide providers through prior‑authorizations, and shared data bridges the two functions. When manufacturers...
![Why Early Detection Matters: Transforming Lung Cancer Care [PODCAST]](/cdn-cgi/image/width=1200,quality=75,format=auto,fit=cover/https://kevinmd.com/wp-content/uploads/unnamed-2-7.jpg)
Why Early Detection Matters: Transforming Lung Cancer Care [PODCAST]
Early detection of lung cancer, especially through low‑dose CT screening, can cut mortality by 20% and prevent one death per 320 screened. Yet only 18% of eligible U.S. patients undergo screening, due to awareness and access barriers. Eli Lilly’s senior oncology...

Why Clinician Education Must Prioritize Nutrition Training
U.S. medical schools allocate fewer than 20 hours to nutrition education, leaving many GI fellows without formal diet training for inflammatory bowel disease. A one‑hour online module dramatically improved fellows' knowledge, confidence, and intention to refer patients to nutrition services....

The Most Important Unanswered Question of the Pandemic
The author invites a high‑stakes debate on whether COVID‑19 vaccines produced a net mortality benefit, demanding analysis of all‑cause mortality data from mid‑2021 to the end of 2022. Participants must rely on up to three official government datasets and five...

Alberta Introduces Bill to Prohibit Assisted Suicide for Minors & the Mentally Ill
Alberta has tabled the Safeguards for Last Resort Termination of Life Act, which would bar medical assistance in dying (MAID) for anyone under 18, for patients whose sole condition is a mental illness, and for cases where death is not...

RFK 'Next To Go'
The blog reports that Robert F. Kennedy Jr. is likely to be ousted from the Health and Human Services post after a federal judge blocked his revised vaccine schedule, with 43% of Americans supporting his removal. It also notes the...

FDA’s New Program Injects Politics Into Drug Approval
The FDA has introduced the Commissioner’s National Priority Voucher (CNPV) pilot, offering ultra‑fast approval pathways for drugs that align with the current White House policy agenda. The program could slash review times for qualifying products, giving participating companies a market...

Why Residents Unionize: Systemic Reform, Not Entitlement
Physician residents are forming unions to confront entrenched hierarchies, unsustainable workloads, and a culture of silent endurance in academic hospitals. The article rebuts a recent JAMA Viewpoint that framed unionization as a perk‑seeking entitlement, emphasizing that burnout persists because systemic...

Looking Beyond Launch: Rethinking Long-Term Patient Support
Manufacturers concentrate patient support on the launch window, emphasizing financial aid and onboarding within the first 30‑60 days. Tina Valbh highlights that this front‑loaded model neglects the evolving barriers patients face throughout long‑term therapy. Without a holistic, multi‑phase strategy, programs...

What’s the #1 Fix When The Neuromonitor Beeps?
A retrospective series of 5,317 pediatric spinal deformity surgeries (1992‑2024) found intraoperative neuromonitoring (IONM) alerts in 4.2% of cases, most often during correction. The study recorded 237 alerts and 348 interventions, with raising mean arterial pressure (MAP) being the most...