Promises And Pitfalls Of Multi-Cancer Diagnostic Tests
Multi‑cancer early detection (MCED) tests analyze blood, urine or saliva for tumor‑derived DNA, RNA or proteins, promising a single‑sample screen for dozens of cancers. While early‑stage detection could complement established organ‑specific programs, sensitivity varies widely, with some cancers identified in as few as 30 % of early cases. High specificity still generates many false positives, leading to costly diagnostic follow‑ups. Medicare will begin covering approved MCED tests in 2028, but coverage is limited and clinical‑utility evidence remains sparse.
ZohoDay 2026 - How Newcross Healthcare Builds AI Apps on a Governed Platform - While Keeping AI Hype at Bay
At ZohoDay 2026, Newcross Healthcare showcased how it built a mission‑critical care‑management application on Zoho’s governed platform, unifying CRM, finance, workforce and analytics. By leveraging Zoho Creator, the team delivered a fully integrated solution in six months, cutting licensing costs...
Key Biosimilars Events of February 2026
February 2026 saw a surge of biosimilar activity, with key regulatory approvals for products such as Sandoz Enzeevu (Eylea), Accord Filkri (Neupogen), and STADA Gotenfia (Simponi) across the US, Canada and the EU. Companies forged new licensing and commercialization deals that extend biosimilar...
Quell Takes New Treg Into Clinic After Transplant Study Halt
Quell Therapeutics has launched the phase 1/2 CHILL trial of its autologous CAR‑Treg therapy QEL‑005 in rheumatoid arthritis and systemic sclerosis, after pausing the liver‑transplant program QEL‑001. The multi‑center study will enroll patients in the UK, Germany and Spain, with read‑out...
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Balancing the Role of Physicians and AI [Video]
At the ViVE conference, Smarter Technologies’ chief medical officer Ruben Amarasingham highlighted the firm’s AI strategy aimed at improving data accuracy while easing physicians’ documentation load. He cited positive customer feedback that the platform reduces administrative burden and delivers clear...
Cigna CEO David Cordani To Retire And Be Replaced By Internal Choice
Cigna announced that long‑time CEO David Cordani will retire on July 1, 2026, and be succeeded by internal candidate Brian Evanko, the current president and chief operating officer. Cordani, who will remain board chair, has led the firm for 17 years,...
Lynk Pharmaceuticals Reports Topline P-III Trial Data on Zemprocitinib in Atopic Dermatitis
Lynk Pharmaceuticals announced topline Phase III data for its oral JAK inhibitor zemprocitinib in 356 patients with moderate‑to‑severe atopic dermatitis. Both the 12 mg and 24 mg doses met the co‑primary endpoints at week 16, delivering 38‑46 percentage‑point improvements in EASI‑75 and roughly 30 percentage‑point gains...
Animal Drugs: Strengthening Federal Incentives Could Help Address Unmet Animal Health Needs
The GAO report reveals that, despite a conditional approval pathway introduced in 2004 and expanded in 2018, FDA‑approved animal drugs for minor species and niche uses remain scarce. From FY2018 through FY2025, only 13 drugs received conditional approval, all targeting...
STAT+: FDA Is ‘Not Convinced’ UniQure’s Huntington’s Therapy Has Benefit, Senior Official Says
The FDA concluded that UniQure’s experimental gene therapy for Huntington’s disease has not demonstrated therapeutic benefit based on existing clinical data. Reviewers said they are not persuaded by the evidence, prompting the agency to block the company from submitting a...
Exclusive: Anti-Ageing Skin Care Conference Keynote Reframes Skin Ageing as Biodesynchronosis
The anti‑ageing skin‑care conference introduced the concept of biodesynchronosis, framing skin ageing as a loss of regulatory coordination rather than merely chronological time. Speakers argued that traditional markers like wrinkles miss upstream failures, and that recovery speed after stress better...
Senate Bill Would Extend Burial Benefits for Veterans Who Receive Hospice Care
Senators John Boozman (R‑AZ) and Gary Peters (D‑MI) have introduced a bipartisan bill to extend Veterans Affairs burial benefits to veterans who die in hospice or other non‑VA health settings. The legislation builds on the 2023 Dole Act expansion, which...
CIOs Agree Variability the Enemy of Large-Scale IT Shops
At a ViVE conference, CIOs from Christus Health, SSM Health and HCA Healthcare warned that variability, not scale, is the primary cost driver for large health systems. They highlighted governance gaps that allow endless project approvals but few rejections, leading...
This Startup Wants To Use Mini Robots To Treat Alzheimer's
Jacksonville‑based startup MMI is preparing the first U.S. microrobotic surgeries to treat Alzheimer’s by clearing lymphatic drainage pathways in the neck. The FDA granted clearance for an initial safety cohort of 15 patients, with five slated for the first procedure...
Innovent Receives the NMPA Approval for Jaypirca to Treat R/R Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (CLL/SLL)
Innovent’s pirtobrutinib, marketed as Jaypirca, received Chinese NMPA approval for adults with relapsed or refractory chronic lymphocytic leukemia/small lymphocytic lymphoma who have undergone at least one prior therapy, including a BTK inhibitor. The decision follows the phase‑III BRUIN CLL‑321 trial,...
CMS Extends Deadline for MFN Pricing Pilot Scheme
The U.S. Centers for Medicare & Medicaid Services (CMS) has pushed back the deadline for manufacturers to join its GENEROUS pilot, extending the initial cut‑off to April 30 while keeping the final deadline at June 30. The voluntary program applies a Most‑Favoured...
Merck and Eisai Present P-III (LITESPARK-011) Trial Data on Welireg + Lenvima in Advanced Renal Cell Carcinoma (RCC) at ASCO...
Merck and Eisai disclosed Phase III LITESPARK-011 results showing that the oral combination of Welireg (belzutifan) and Lenvima (lenvatinib) outperformed cabozantinib in 747 patients with advanced renal cell carcinoma who progressed after anti‑PD‑1/PD‑L1 therapy. At a median follow‑up of 29...
Whitepaper: Digital PSA Surveillance: Using Remote Monitoring for Stable Cancer to Avoid Unnecessary Attendances and Optimise Clinical Capacity
Isla Health’s new whitepaper outlines how NHS trusts can digitise PSA surveillance to cut unnecessary urology follow‑ups. By automating data capture, trusts can process patients 87% faster and slash administrative work by up to 80%, freeing clinical nurse specialists for...
Dermatology Trials by the Numbers: Key Trends and Benchmarks for 2026
Dermatology research is booming, with more than 16,000 trials completed, ongoing, or planned by the end of 2025. The Asia‑Pacific region now hosts roughly 8,000 studies, a five‑fold increase over the past decade, matching North America and Europe combined. Low...
East Cheshire Shares Five Aims for 2026 and Beyond Following EPR Rollout
East Cheshire NHS Trust announced five strategic aims for 2026 following a smoother‑than‑expected Meditech EPR go‑live in June 2025. The plan includes a major system upgrade in March, digitising the top 50 high‑priority clinical documents, and expanding internal referral orders...
Few U.S. Doctors Have Seen Measles in Person. That’s a Problem.
In January, twin brothers with measles were treated at Mission Hospital in Asheville, North Carolina, but staff failed to isolate them for over four hours, exposing at least 26 other patients. A CMS investigation placed the hospital in Immediate Jeopardy,...
Clinically‐Relevant Static Magnetic Field Induces Release of Encapsulated Molecules From Magnetoliposomes
Researchers demonstrated that a clinically‑available 1.5 T static magnetic field can trigger the release of encapsulated molecules from magnetoliposomes (MLs). The study used citric‑acid‑stabilized Fe₃O₄ nanoparticles, with and without a chitosan coating, and monitored structural changes via SAXS and DLS. Fluorescence...
Designing Telehealth for Every Age: What Providers Need to Know About Serving Older Adults
Telehealth’s rapid expansion has left older adults behind because most platforms ignore age‑related cognitive, sensory, and usability challenges. Studies show that while over half of seniors are interested in video visits, only a third feel comfortable using them, highlighting a...
Navigating the FDA After the Storm To Advance Drug Candidates
After a wave of senior departures and a 3,500‑position cut, the FDA entered 2026 with a largely inexperienced workforce, raising uncertainty for drug developers. The agency’s new AI guidance, released in January, outlines best practices but emphasizes human oversight and...
60% Of Older Adults Prefer At-Home Care If Their Needs Increase
A Pew Research survey of 2,582 U.S. adults aged 65 and older finds that 60% would rather stay at home with a caregiver if they can no longer live independently, while only 18% prefer moving to an assisted‑living community. Preference...
Repeal Of Motorcycle Helmet Laws Are Dangerous And Expensive
A University of Michigan study examined the impact of Michigan’s 2022 repeal of its universal motorcycle‑helmet law. Researchers found hospital costs rose by $5,785 per injured rider—a 26% increase—adding more than $4.5 million in annual expenses, or $6.4 million when adjusted to...
FDA Clears Ultrasound AI Tool for Accurate Delivery-Date Prediction
The U.S. Food and Drug Administration granted De Novo clearance to Ultrasound AI’s Delivery Date AI, a cloud‑based software‑as‑a‑medical‑device that predicts a pregnant woman's delivery date using only standard ultrasound images. The model was trained on more than one million...
Where Are the Doctors? Patients Leading the Conversation on TikTok About Hidradenitis Suppurativa in Skin of Color
A new JMIR Dermatology study finds TikTok is the primary education source for patients with hidradenitis suppurativa (HS) in skin of color. Researchers analyzed 50 videos and discovered that nearly half were patient‑generated, while only about 20% featured dermatologists. Physician‑authored...
908 Devices Inc (MASS) Q4 2025 Earnings Call Transcript
908 Devices reported Q3 2025 revenue of $14 million, a 4% year‑over‑year decline but an 8% sequential increase, driven largely by FTIR‑based Explorer devices. Adjusted EBITDA loss narrowed to $1.8 million, a 53% quarter‑over‑quarter improvement, marking the smallest loss since the company...
Cryoport Inc (CYRX) Q4 2025 Earnings Call Transcript
CVRx reported fourth‑quarter 2025 revenue of $16 million, a modest 4% year‑over‑year increase, while gross margin improved to 86% driven by higher selling prices and manufacturing efficiencies. Net loss widened to $11.9 million as SG&A and R&D expenses outpaced revenue growth, but...
Evolus Inc (EOLS) Q4 2025 Earnings Call Transcript
Evolus Inc. reported fourth‑quarter 2025 net revenue of $90.3 million, a 14% year‑over‑year increase, and full‑year revenue of $297.2 million, marking a sixth consecutive double‑digit growth year. Jeuveau drove the bulk of sales, achieving over 14% U.S. market share, while the newly...
Neuropace Inc (NPCE) Q4 2025 Earnings Call Transcript
NeuroPace reported fourth‑quarter 2025 revenue of $26.6 million, a 24% year‑over‑year increase driven primarily by a 26% rise in RNS system sales to $22.4 million. Gross margins improved to 77.4% overall and 80.5% for the RNS product, while operating expenses grew slower...
SOPHiA GENETICS SA (SOPH) Q4 2025 Earnings Call Transcript
SOPHiA GENETICS reported Q4 2025 revenue of $19.5 million, up 23% year‑over‑year, marking the third consecutive quarter of accelerating growth. The company added 31 new customers, bringing total 2025 signings to 94, and saw U.S. revenue rise 30%, highlighting strong market...
Investors Welcome Bradesco Healthcare Shakeup
Brazilian financial giant Bradesco announced it will consolidate all of its healthcare holdings into a single, publicly listed division. The restructuring creates a dedicated health platform that will house hospitals, insurance operations, and ancillary services under one corporate umbrella. Investors...
NDA and BLA Calendar Year Approvals
The FDA’s Center for Drug Evaluation and Research (CDER) has published its annual New Drug Application (NDA) and Biologics License Application (BLA) approval reports for calendar years 2015 through 2025, each linked in a consolidated list. These reports detail the...
Cost and Trust Drive Post-Acute Care Decisions, Nursing Home Choices – U.S. News Survey
The U.S. News survey of 206 recent discharges found trust to be the dominant factor—93% rated it extremely or very important—slightly outweighing clinical quality. Cost was the top driver when choosing between home health and skilled nursing, yet many respondents...
5 Notable Health Tech Funding Announcements in February
February saw a wave of sizable health‑tech financings, with Talkiatry closing a $210 million Series D, Honest Health raising $140 million, Solace securing $130 million in Series C, Garner Health obtaining $118 million in Series D, and Midi Health completing a $100 million Series D that pushes its valuation...
Frontline Honors Award Winner: Ashley Lott, Certified Nursing Assistant, Litchfield Health & Rehab Center
Ashley Lott, a Certified Nursing Assistant at Litchfield Health & Rehab Center, has been named to the Frontline Honors Awards Class of 2025 by Skilled Nursing News. The award, driven by peer nominations, recognizes frontline workers who deliver exceptional resident...
New Diagnostic Markers for Multiple Sclerosis Discovered in Cerebrospinal Fluid
Researchers from the Max Planck Institute of Biochemistry and the Technical University of Munich applied high‑throughput mass spectrometry to cerebrospinal fluid from more than 5,000 patients, measuring roughly 2,000 proteins per sample. They identified a 22‑protein panel that distinguishes multiple...
What ‘The Pitt’ Gets Right About Obesity That Real Medicine Often Misses
A recent episode of the TV drama *The Pitt* highlighted a stark contrast between typical obesity‑related bias in medical settings and a model of care that treats the patient’s acute condition without judgment. The show depicted clinicians adapting equipment and...
One PSMA Agent Outshines Competitors at Detecting Prostate Cancer Recurrence
A head‑to‑head study of 55 post‑prostatectomy patients compared two FDA‑cleared PSMA PET agents, Posluma (flotufolastat F‑18) and Pylarify (piflufolastat F‑18). Posluma demonstrated markedly lower bladder radioactivity, with a median bladder SUV of 10.9 versus 29 for Pylarify. This reduction translated into higher...
Frontline Honors Award Winner: Vanessa Valerio, RN, CMC, CHCA, Vice President and Chief Operating Officer, Care Indeed
Vanessa Valerio, RN, CMC, CHCA, Vice President and COO of Care Indeed, has been named to the Frontline Honors Awards Class of 2025 by Home Health Care News. The award recognizes frontline workers who deliver exceptional experiences, advocate for the...
How Flatworms Keep Their Regeneration Powers on Track
Scientists have identified a molecular checkpoint that guides planarian stem cells during regeneration. The roundabout A receptor (RoboA) suppresses inappropriate pharyngeal differentiation by regulating the transcription factor FoxA, while the extracellular protein Anosmin1a partners with RoboA to fine‑tune cell identity...
Ultrasound-Activated 'Nanoagents' Kill Superbugs Hiding in Biofilms
Scientists at the University of Birmingham and Nottingham Trent University have created silica‑based nanoagents that encapsulate the hydrophobic antibiotic rifampicin and release it only when exposed to low‑frequency ultrasound. The ultrasound‑triggered particles penetrate deep into Staphylococcus aureus biofilms, achieving a...
Plan to Attend 2026 AHA Annual Meeting
The American Hospital Association (AHA) is intensifying its policy engagement ahead of the 2026 AHA Annual Meeting, issuing recommendations on health data deregulation and technology interoperability. It submitted statements to multiple congressional hearings, addressing physician burnout, health‑care cost reduction, and...
FDA Adverse Event Reporting System (FAERS) Electronic Submissions
The FDA has mandated electronic submissions to the FAERS database using the ICH‑endorsed E2B(R3) standard, beginning January 16 2024 for post‑marketing drug and biologic reports and April 1 2024 for pre‑marketing IND safety reports. Companies have until April 1 2026 to transition fully, after which only...
AHA’s Hood Shares How Governance, Trust Can Shape Health Care Organizations
American Hospital Association’s Trustee Insights features Executive Vice President and COO Michelle Hood, who draws on four decades of leadership to discuss how strong governance, trust, and active board engagement can build resilient health‑care organizations. The piece underscores the need...
Report: Colorectal Cancer Rates Continue Declining Among Older Adults While Incidents Climb for Younger Adults
A new American Cancer Society report shows colorectal cancer rates keep falling among adults 65 and older, while incidence climbs sharply for younger adults. The surge in younger patients is driven by a rise in rectal cancer, now accounting for...
Insurance Exec: ‘We Are All To Blame’ For Failure Of US Health System
Ascendiun CEO Paul Markovich announced Worthy, a new lobbying effort funded by his company to overhaul the U.S. health‑care system. The initiative, launched with Mark Cuban, targets insurer‑driven inefficiencies such as outdated provider directories, burdensome prior‑authorization, and excessive administrative costs. Markovich...
How Healthcare Organizations Can Build Ransomware Resilience
Scott Doerr, virtual CISO at Fortified Health Security, will present a session on ransomware resilience at HIMSS 2026. He outlines a phased approach that moves ransomware from a reactive crisis to a managed operational risk, emphasizing assessment, planning, simulation, execution,...
VA Health Care: Recommendations and Observations to Improve Community Care and Support for Caregivers Related to the Dole Act
GAO reports that the Veterans Health Administration has yet to fully implement recommendations aimed at improving the Veterans Community Care Program and Caregiver Support Program, as mandated by the 2025 Dole Act. Staffing shortfalls, missing wait‑time metrics, and inconsistent referral...