Rising Pediatric Diabetes Trends in US Medicaid, CHIP Enrollees
New JAMA Network Open analysis shows pediatric diabetes prevalence among Medicaid and CHIP enrollees rose from 2.73 to 3.04 per 1,000 between 2016 and 2021, an 11.4% increase. Type 2 diabetes drove most of the growth, climbing 24.3% with especially sharp rises among boys (48%) and children in the Western United States (52%). Rural children consistently exhibited higher absolute rates, though urban populations experienced a larger relative increase. The study highlights gaps in claims‑based identification and incomplete demographic data, underscoring the need for targeted screening and resource allocation.
FDA's Adverse Event Reporting System (FAERS)
The FDA Adverse Event Reporting System (FAERS) is a public database that collects adverse event, medication error, and product quality complaint reports for drugs and biologics after market approval. It follows the ICH E2B international safety reporting guidance and uses...
Early Add-On Therapy Associated With Strong Clinical Response in MG
A multicenter retrospective registry of 153 AChR‑positive generalized myasthenia gravis patients found that initiating add‑on immunotherapy within 24 months of diagnosis (early intensified treatment) produced faster and larger improvements in MG‑ADL, QMG, and quality‑of‑life scores than later escalation. Early patients...
Data From Insight Hospital and Medical Center Leaked on Dark Web
Insight Hospital and Medical Center disclosed that an unauthorized actor accessed its network from August 22 to September 11, 2025, compromising extensive personal and health data. The breach involved roughly 360 GB of files—about 900,000 records—including names, Social Security numbers, and medical images. On...
Tampa General Hospital Adopts LIBERTY Endovascular Robotic System
Tampa General Hospital has become the first health system in Florida to adopt Microbot Medical’s LIBERTY Endovascular Robotic System, following the device’s FDA 510(k) clearance. LIBERTY is a single‑use, remotely operated robot designed for peripheral endovascular procedures, promising greater precision...
Ultrasound Isn't Cutting It for Diagnosing Pediatric Appendicitis, New Data Show
A recent analysis in Emergency Radiology compared ultrasound, CT, and rapid MRI for diagnosing pediatric appendicitis. Ultrasound was nondiagnostic in over half the cases, delivering only 65.3% sensitivity, while rapid MRI achieved 96‑97% sensitivity and 98% specificity. Although ultrasound resulted...
Ultrasound Reporting Platform Gets FDA Approval
AS Software announced that its next‑generation ultrasound reporting platform, Asera, received 510(k) clearance from the U.S. Food and Drug Administration. The cloud‑based solution retains core reporting functions while delivering a redesigned user interface, streamlined workflows, and scalable architecture. Asera includes...
Water Interactions Reveal How Surface Coatings Reshape Nanoparticle Drug Delivery
Arizona State University researchers quantified how water interacts with biomolecule‑coated magnetite nanoparticles, revealing that surface coatings dramatically reshape hydration energetics, immune recognition, and drug‑delivery performance. Using a calorimetry‑gas adsorption system, they measured water adsorption on particles coated with bovine serum...
Best Practices for Conducting and Reporting Pharmacoepidemiologic Safety Studies Using Electronic Healthcare Data Sets
The FDA issued a final guidance document outlining best practices for conducting and reporting pharmacoepidemiologic safety studies that rely on electronic healthcare data, such as administrative claims and electronic medical records. It prescribes how sponsors should document study design, analytical...
Chair File: Leadership Dialogue — Insights and Innovation in Rural Hospitals with Mark Boucot of Potomac Valley Hospital
Mark Boucot, CEO of Potomac Valley Hospital, a 25‑bed critical access facility in West Virginia, received the inaugural AHA Rural Hospital Excellence in Innovation Award. He highlighted the hospital’s low‑cost virtual ICU, built with simple tablets for remote intensivist support,...
With Quantum Transformation Looming, No Time to Waste in Maturing Cryptography Management
Quantum computers can break RSA and ECC encryption in seconds, prompting urgent action for healthcare data security. At HIMSS26, DigiCert’s Mike Nelson and other experts will outline practical steps for post‑quantum cryptography (PQC) migration, emphasizing crypto agility and automated management....
Researchers Use Dynamic Digital Radiography to Quantify Functional Outcomes After Total Shoulder Arthroplasty
Emory Healthcare researchers used Konica Minolta's Dynamic Digital Radiography (DDR) to compare anatomic and reverse total shoulder arthroplasty (aTSA and rTSA) in 71 shoulders versus 32 healthy controls. The DDR cine‑loop analysis showed that both procedures restored scapulohumeral rhythm (SHR)...
Elevating the Role of Advanced Practice Providers in the Evolving Alzheimer Disease Landscape
Alzheimer disease is set to affect 152 million people by 2050, driving a trillion‑dollar economic burden. New anti‑amyloid monoclonal antibodies demand early, accurate diagnosis, prompting health systems to enlist advanced practice providers (APPs) for screening, treatment coordination, and caregiver support. Panels...
Why You Shouldn’t Panic About GLP-1 Muscle Loss
GLP‑1 agonists such as Wegovy are driving rapid weight loss, prompting concerns that users may experience significant muscle loss. While people with obesity typically possess more absolute muscle, weight reduction naturally sheds some lean tissue, and researchers have not yet...
Moderna’s Dual Covid-Flu Vaccine Poised for EMA Approval on Positive CHMP Take
The European Medicines Agency’s CHMP has issued a positive opinion on Moderna’s mCombriax, a combined COVID‑19 and influenza mRNA vaccine, after a Phase III trial showed stronger immune responses than a mixed regimen of Sanofi’s flu shot and Spikevax. EMA approval...
Other News to Note for March 2, 2026
At CROI 2026, researchers spotlighted the growing neurodegenerative burden among aging people living with HIV, emphasizing heightened risks of depression and cognitive vulnerability despite long‑term antiretroviral therapy. Parallelly, the University of Southern California announced a novel series of MAPT aggregation...
Virtual Crisis Care Helps Rural Communities Access Mental Health Resources in Emergencies
Virtual Crisis Care (VCC) programs give rural law enforcement instant video access to behavioral health clinicians, allowing real‑time assessment and de‑escalation of mental‑health emergencies. In South Dakota, the model has been active for over five years across more than 30...
In the Clinic for March 2, 2026
BioWorld’s “In the Clinic for March 2, 2026” page functions as a centralized gateway to the latest biopharma, med‑tech, and scientific content. It aggregates data snapshots, special reports, infographics, and market scorecards covering everything from GLP‑1 trends in China to mRNA vaccine...
Regulatory Actions for March 2, 2026
On March 2, 2026 BioWorld published a regulatory snapshot covering biopharma and med‑tech firms such as AS Software, Asieris, Boehringer Ingelheim, Deephealth, Eli Lilly, Ipsen, Moderna, Neurogene, Novartis, Optellum, Photocure, Regeneron, Sanofi, Sentynl, Synergy Spine Solutions and X4. The roundup highlights...
Pregnancy And Colon Cancer Share Symptoms, Often Delays Diagnosis.
Pregnant women may mistake colorectal cancer warning signs for normal pregnancy discomfort, leading to delayed diagnosis. Lori Charney’s case illustrates how constipation, abdominal pain and rectal bleeding were attributed to pregnancy until stage IV cancer was discovered postpartum. Experts note that...
Medicare's Continued Support for Telemedicine Signals Stability, Legitimacy
Medicare has extended its telehealth reimbursement flexibilities through 2027, preserving payment for a broad array of virtual services. Behavioral health telehealth restrictions were made permanent in 2021, removing geographic and originating‑site limits. The DEA also prolonged its telemedicine prescribing allowances...
Contributor: Personalized Heart Risk and How AI-Powered Plaque Analysis Is Changing Prevention
AI‑enhanced coronary CT angiography (CCTA) now quantifies total and non‑calcified plaque, delivering risk information that calcium scoring alone misses. Large studies show that incorporating AI‑driven plaque metrics reduces heart attack or cardiac death risk by up to 41% and boosts...
Income Inequality Fuels Worsening Birth Outcomes
A new JAMA Pediatrics study using PRAMS data from 2012‑2022 examined 380,499 births and found that low‑income mothers experienced a widening gap in low‑birth‑weight infants, rising 2.2 percentage points versus a 0.6‑point increase for higher‑income groups. The analysis revealed that...
Why Novo Nordisk's Ireland Expansion Is Key to Fighting Off Eli Lilly
Novo Nordisk announced a €432 million ($506 million) investment to expand its Athlone, Ireland facility, increasing capacity for oral products such as the newly launched Wegovy pill. The expansion is intended to secure supply outside the United States and help the company...
Champion Insights Opens Nationwide Enrolment to Study ALS Risk in High-Performance Groups
Champion Insights has launched a nationwide enrollment to recruit up to 500 elite athletes, military veterans and first responders for a study investigating their elevated risk of amyotrophic lateral sclerosis (ALS). The remote study will collect blood samples and online...
HAP Foundation, Northwestern University Launch Palliative, Hospice Care Educational Initiative
The HAP Foundation and Northwestern University’s EPEC program have launched a 12‑month clinical training initiative aimed at Illinois‑based hospice and palliative care providers serving rural communities. Beginning in April, the curriculum combines monthly virtual video sessions with in‑person kickoff and...
Bioresearch Monitoring Information System (BMIS)
The FDA’s Center for Drug Evaluation and Research has released the Bioresearch Monitoring Information System (BMIS), a searchable database that catalogs clinical investigators, contract research organizations, and institutional review boards linked to IND submissions since October 1, 2008. The dataset is updated...
Victoria Leeds Admits Randox Health for Regional Debut
Victoria Leeds, owned by Redical, announced that Randox Health will open its first standalone clinic in Yorkshire, occupying a 734 sq ft unit in the Victoria Quarter. The clinic will provide a full suite of blood tests, comprehensive health checks, specialised diagnostics...
Medicare Advantage Reckoning Hits 2026 Enrollment: Mark Meiselbach, PhD
New research predicts that nearly 3 million Medicare Advantage (MA) enrollees—about 10 % of the market—will be forced out of their plans in 2026 as payment reforms curb historic over‑payments. The exits will hit rural beneficiaries hardest and will deepen the divide...
Ventricular Recovery Program Enables Kids to Have VADs Explanted
A standardized ventricular recovery program at Children’s Hospital of Philadelphia enabled 26% of pediatric VAD patients to have the device explanted, far exceeding the typical 4‑6% national rate. The protocol, built on four pillars—mindset, goal‑directed medical therapy, standardized surveillance, and...
Looking Beyond AI Implementation at HIMSS26
HIMSS CEO Hal Wolf announced that the AI track at HIMSS26 will move beyond pure deployment discussions. The conference will spotlight AI governance frameworks, the impact on clinical and administrative workflows, and concrete methods for calculating return on investment. By...
CPHI Middle East 2026 | 11-13 May, Riyadh
CPHI Middle East will return to Riyadh in May 2026, building on the 2024 edition that attracted over 30,000 visitors from more than 100 countries. The event promises expanded networking opportunities, direct market access, and the latest regulatory and innovation...
The Paper-Thin Implant That Listens To Your Brain Signals
Researchers published in Nature Electronics a hair‑thin, flexible patch called BISC that places 65,536 micro‑electrodes on the brain’s surface for high‑resolution electrocorticography. The device can address up to 1,024 channels simultaneously and transmits data wirelessly, eliminating percutaneous cables. Animal tests...
Virtual Reality Takes Next Step in Eye Care
Virtual reality is moving from experimental demos to practical tools in ophthalmology, highlighted by the FDA‑cleared Luminopia therapy for amblyopia and patient‑focused IOL simulators such as VirtuaLens and InSightVR. Surgeons are adopting VR for training, with platforms like Eyesi and...
Victoria Leeds Admits Randox Health for Regional Debut
Victoria Leeds, operated by Redical, has secured Randox Health for its first standalone clinic in Yorkshire, occupying a 734 sq ft space in the Victoria Quarter. The new clinic will provide a full suite of preventative health services, including comprehensive blood tests,...
Johnson & Johnson Launches 3 New Stroke Devices
Johnson & Johnson MedTech launched three new stroke devices—Cereglide 42 and Cereglide 57 aspiration catheters and the Innerglide 7 delivery aid—expanding its aspiration‑first portfolio. The catheters feature a multi‑axial shaft, radiopaque tips and hydrophilic coating to improve navigation of distal clots. Innerglide 7 provides...
Bioxytran Reports Positive Phase 1b/2a Results for Antiviral ProLectin‑M
Bioxytran announced positive phase 1b/2a data for its oral antiviral ProLectin‑M in a randomized, double‑blind, placebo‑controlled trial of 39 mild‑to‑moderate COVID‑19 patients in India. The highest dose (16,800 mg/day) achieved viral clearance in 90% of participants by day 5 versus 20% on placebo,...
From Principle to Practice: New Checklist Supports Patient Engagement in Rare Disease Value Research
The Center for Innovation & Value Research launched the Rare Disease Patient Engagement (RDPE) Guidance and Checklist, a practical toolkit to embed patient and caregiver input throughout rare‑disease comparative effectiveness research, value assessment, and economic modeling. The resource bundles best‑practice...
Curbside Consult with Dr. Jayne 3/2/26
The article sketches a typical week for a clinical informaticist, showing how patient care, system design, feedback loops, governance, safety, and evidence assessment intertwine. It highlights that a single day can involve everything from bedside interaction to long‑term technology strategy....
4 Large-Cap Pharma Stocks to Watch as Industry Recovery Gains Steam
The large‑cap pharmaceutical sector is rebounding in 2026 after a muted 2025, buoyed by strong quarterly results, aggressive M&A, and robust pipeline activity. Zacks ranks the industry at #172, but it posted a 10.8% gain over the past year, outpacing...
Vueway Expands Pediatric Use: Alberto Spinazzi Shares Bracco Group’s Vision
The European Union has granted approval for Vueway (gadopiclenol) to be used in neonates, infants, and toddlers, marking a pivotal expansion of pediatric MRI contrast agents. Vueway delivers diagnostic‑grade imaging at half the dose of conventional macrocyclic GBCAs, thanks to...
Safety Concerns Spur Aardvark to Halt Key Prader-Willi Drug Trial
Biotech Aardvark Therapeutics announced a voluntary pause of the Phase 3 HERO trial for its Prader‑Willi drug ARD‑101 after routine safety monitoring identified reversible cardiac observations in healthy volunteers receiving supratherapeutic doses. The pause affects both the main trial and an...
Merck, Pfizer’s Drug Combo ‘Rewrites the Standard of Care’ in Bladder Cancer
Merck and Pfizer’s Keytruda‑Padcev doublet delivered a dramatic survival advantage in the Phase 3 EV‑304 study of muscle‑invasive bladder cancer. The regimen cut the risk of disease progression, recurrence or death by 47% compared with gemcitabine‑cisplatin and lowered overall‑mortality risk by...
Sexual Health Education: HHS Could Improve Efforts to Assess Grantee Performance
The GAO report finds that the Department of Health and Human Services (HHS) administers Sexual Risk Avoidance Education (SRAE) grants but relies mainly on near‑term performance measures focused on program reach rather than youth outcomes. While HHS reviews curricula for...
Tuesday Health Expands Footprint to Ohio With Buckeye Health Plan Partnership
Tuesday Health has partnered with Buckeye Health Plan to extend its palliative‑care model across Ohio, reaching the plan’s 400,000 Medicaid, Medicare and Marketplace members. The collaboration delivers an interdisciplinary team—including nurses, social workers, NPs and physicians—through in‑person, hybrid and virtual...
Big Pharma’s Next Entrant Could Come From China
Chinese drugmakers, led by Jiangsu Hengrui Pharmaceuticals, are emerging as global biotech contenders. Hengrui topped 2024 trial sponsorship, boasts a pipeline of 100 investigational drugs and 400 trials, and secured a $500 million partnership with GSK that could yield $12 billion. Analysts...
Radiology Artificial Intelligence Firm Asks FDA to Exempt Certain Devices From Premarket Review
Harrison.ai filed a citizen petition asking the FDA to grant optional pre‑market exemption for radiology computer‑aided detection (CAD) devices, allowing manufacturers with an existing cleared product to launch similar tools without a new 510(k). The agency must issue a rapid...
Nuclear Medicine Firm Shine Technologies Raises $240M
Shine Technologies announced a $240 million financing round led by Patrick Soon‑Shiong’s NantWorks, bringing its total capital raised to over $1 billion. The infusion will accelerate the company’s commercial fusion initiatives and expand its Lu‑177 isotope production, a cornerstone of targeted cancer...
Segmed Partners with Verily to Expand Access to Real-World Imaging Data
Segmed, a leader in real‑world medical imaging, announced a partnership with Verily to make its de‑identified, diagnostic‑grade imaging datasets available on Verily’s AI‑native Pre Exchange and Workbench platforms. The initial offering is a longitudinal breast‑cancer cohort featuring digital breast tomosynthesis...
Clinical Labs Gain Ground with Noninvasive Dd-cfDNA Transplant Surveillance
A new donor‑derived cell‑free DNA (dd‑cfDNA) blood test is transforming post‑transplant surveillance by providing real‑time, noninvasive insight into graft health. The assay quantifies donor DNA fragments released when a transplanted organ is injured, offering a high negative predictive value that...