Corcept Therapeutics Shares Surge 20% on FDA Approval of Lifyorli
Corcept Therapeutics saw its shares climb almost 20% after the U.S. FDA approved its lead drug Lifyorli in combination with nab‑paclitaxel for platinum‑resistant ovarian, fallopian tube and primary peritoneal cancer. The approval, based on a 381‑patient trial, validates the company's cortisol‑modulation approach and ignites fresh investor enthusiasm.
Unplanned Nomad Life Cripples Productivity Across Time Zones
I'm a digital nomad right now... and I really hate it. I've spent the last 6 weeks in Bangkok + Germany, working on 12 hour time differences from New York, and I find it damn near impossible to accomplish my professional...
Locals Approve First Ski Resort In Nevada's "Swiss Alps", But There's a Private Catch
Elko County’s Planning Commission approved a private ski resort on Peter Christodoulo’s Ruby Mountain Ranch in a 5‑2 vote. The conditional use permit allows five three‑seat chairlifts, a lodge with five guest rooms, and limits use to the owner’s family...
Broad Collaboration Produces High-Resolution Atlas of Developing Human Brain
Johns Hopkins scientists have assembled the most detailed cellular atlas of the human neocortex, merging data from nearly 200 studies and over 30 million cells. The open‑access web portal makes the high‑resolution map available to researchers worldwide, facilitating exploration of gene‑expression...
Byte Sized Lessons Launches Cyber‑Safety Adventure Series for Kids
Byte Sized Lessons with Zola and Zena, written by cybersecurity expert Dr. Rae Rivera, has been released worldwide as a new educational adventure for young readers. The book combines storytelling with hands‑on activities to teach children core online‑safety skills, targeting...
Ken Griffey Jr. Named Primo Brands' First "CEO of H2O" For 2026 MLB Campaign
Primo Brands has appointed baseball legend Ken Griffey Jr. as its inaugural "CEO of H2O" and rolled out a unified healthy‑hydration campaign across its six regional spring‑water brands for the 2026 MLB season. The move ties a sports icon to...
Awe Shrinks Problems, Boosts Perspective
There's this thing that happens when you stand in front of something so big your brain can't quite process it. Dacher Keltner at UC Berkeley calls it awe, and his research suggests it does something interesting to us. It makes our...
AI's Influence on Human Thought Tops Amazon Rankings
🤔Something very interesting is happening. My book on AI and human cognition is now showing up on Amazon’s top lists in: 🔴Epistemology 🔴Cognitive Psychology 🔴Medical Cognitive Psychology Interestingly, this distribution wasn’t planned. The larger conversation is now shifting, and not about what AI can do, but...
The Bear House Rolls Out Shop-in-Shop Format Across 15 Shoppers Stop Stores
The Bear House, a smart‑casual menswear label, is launching a shop‑in‑shop (SIS) concept in more than 15 Shoppers Stop locations across India. The rollout spans seven cities—including Bengaluru, Pune, Hyderabad, Kolkata, Lucknow, Ahmedabad and Jaipur—aiming to broaden the brand’s offline...
TRIBE V2 Predicts Brain Responses to Any Stimulus
Today we're introducing TRIBE v2 (Trimodal Brain Encoder), a foundation model trained to predict how the human brain responds to almost any sight or sound. Building on our Algonauts 2025 award-winning architecture, TRIBE v2 draws on 500+ hours of fMRI recordings...
Are We Ready to Mine the Moon?
Interlune, a lunar‑resource startup, announced that its first customers are ready to purchase helium‑3 extracted from the Moon. Helium‑3 is touted as a fuel for next‑generation nuclear fusion reactors that produce no long‑lived radioactive waste. The company highlights the technical...
CCEM Lands $15.5 M CFI Grant to Boost Canada’s Nano‑characterisation Platform
The Canadian Centre for Electron Microscopy (CCEM) has been awarded a $15.5 million grant from the Canada Foundation for Innovation. The funding will expand national nano‑characterisation capabilities, linking atomic‑scale insights to Canada’s critical‑minerals strategy, semiconductor supply chain and electronic‑waste recycling efforts.
The 7 Things Parents Raising Grateful Kids Do that Feels Backwards
Psychologists identify seven counterintuitive habits that help parents raise genuinely grateful children, from thanking kids first to discussing gratitude casually. Research shows that modeling gratitude, setting clear limits, and being transparent about family finances foster authentic appreciation. Parents who call...
The Sea Monster Goes ‘Bloop’—Or Does It?
In 1997 NOAA’s hydrophone network captured an ultra‑low‑frequency, extremely loud underwater sound dubbed the “Bloop,” heard across sensors spaced over 3,000 miles. Initial speculation ranged from a giant sea creature to shifting ice, but acoustic analysis later matched the signature...
Sourdough Bread Benefits May Come From Specific Fiber
Scientists at Vrije Universiteit Brussel discovered that the acidic environment of sourdough activates wheat enzymes, breaking down arabinoxylan fibers. The conversion turns water‑extractable arabinoxylans into water‑unextractable forms, altering dough texture and digestibility. Specific bacteria, such as Lactococcus lactis and Limosilactobacillus...
Precigen Posts 149% Revenue Surge, Forecasts $18M Q1 as Papzimius Gains Momentum
Precigen (PGEN) reported fiscal Q4 2025 revenue of $9.7 million, up 149% year‑over‑year, and projected first‑quarter 2026 sales to exceed $18 million. The surge stems from the rapid commercial rollout of its FDA‑approved gene‑therapy Papzimius and broader payer coverage across the United...
ALBUM REVIEW: On ‘Hurts Like Hell,’ Charlotte Cornfield Lets It All In
Charlotte Cornfield’s new album *Hurts Like Hell* marks her most intimate work to date, directly inspired by her recent transition to motherhood. The record balances stark, confessional lyrics with lush folk‑rock arrangements, showcasing a vocal confidence that has deepened over six...
How to Turn a Chicken Egg Into a Drug Factory
Biotech start‑up Neion Bio is pioneering a method to turn chicken embryos into miniature drug factories. Scientists micro‑inject genetic constructs into three‑day‑old embryos, reprogramming the developing bird to synthesize pharmaceutical compounds within the egg. The approach promises faster, cheaper production...
March 26, 2014: A Ringed Centaur
In June 2013 a coordinated occultation campaign across South America captured the centaur Chariklo passing in front of star UCAC4 248‑108672, revealing two brief dimming events that indicated the presence of rings. The finding, published in *Nature* and announced on March 26 2014,...
Tim Blanks to Be Honoured at Canadian Arts & Fashion Awards
Fashion journalist Tim Blanks will be honored with the Vanguard Award at the Canadian Arts & Fashion Awards (CAFA) gala in Montreal on April 23. The ceremony, a marquee event for Canada’s fashion ecosystem, also recognizes designer Sophie Theallet, Groupe Dynamite CEO Andrew Lutfy, and...
Foreigner Adds Dates To 50th Anniversary Tour
Foreigner has expanded its 50th‑anniversary tour, adding new U.S. stops in Albuquerque, El Paso, Scottsdale and Reno, bringing the itinerary to over 90 shows through 2027. The celebration already includes acoustic shows in Colorado, a Las Vegas orchestral residency, a spring Florida...
Newfound Giant Virus Holds Clues to How Complex Life Evolved
Researchers have identified a new giant DNA virus, ushikuvirus, isolated from a freshwater pond near Tokyo. The virus infects the amoeba Vermamoeba vermiformis and carries a full complement of eukaryote‑like histone genes. Unlike its relative medusavirus, ushikuvirus destroys the host...
Decoding the Phosphorus Puzzle: How Microplastics and Hydrochar Transform Nutrient Dynamics in Rice Paddies
Researchers at Nanjing University found that adding manure‑derived hydrochar or thermoplastic polyurethane microplastics to rice‑paddy soils significantly boosts labile phosphorus—by 21.1% and 14.2% respectively. Hydrochar supplies readily degradable carbon, spurring fast‑growing copiotrophic bacteria that rapidly solubilize phosphorus. In contrast, the...
Scion by Thomas Ha (Audio)
In this episode of The Fourth Story, host Kate Baker narrates Thomas Ha’s speculative short story “Scion,” set in a constantly reconfiguring manor that mirrors the deteriorating mind of the protagonist’s father, the Leavenlord. The tale follows a young heir...
Red Kettle Rebound: Salvation Army Raised $154 Million
The Salvation Army reported $154 million raised during the 2025 holiday season, combining $103 million from its iconic red kettle street collections and $51 million from digital donations. Contributions grew 4% in‑person and 8% online despite a shorter holiday period. The total approaches...
March Heat Forces Another Colorado Ski Resort To Close Early
Purgatory Resort in Colorado announced it will shut down on March 29, 2026, a full month earlier than usual because of an unusually warm winter and depleted snowpack. The decision follows a historic heat wave that left the Western U.S....
African Safari: On Three Legs
During a 2024 African safari, the author and guide CJ pursued a prized kudu named Half‑Horn but were diverted by a juvenile wildebeest missing a hind leg, trapped by a poacher’s snare. The author shot the crippled animal twice, delivering...
Exercise Beats Optional: Key for Prostate Cancer Survival
As a medical school professor, I can tell you: the textbooks got this one wrong. We taught that once you have prostate cancer, exercise is nice but optional. New data says it may be the most powerful tool in your arsenal. 828...
New Title for Herbert Blomstedt
Renowned Swedish conductor Herbert Blomstedt, now 98, was appointed honorary conductor of the Norrköping Symphony on March 26, 2026. The orchestra marks the occasion as a homecoming, since Blomstedt launched his professional career there in 1954 and led as principal...
The Twilight Sad Make a Welcome Return
After a seven‑year hiatus, Scottish indie‑rock band The Twilight Sad returns with *It’s the Long Goodbye*, their first studio album since 2016. The record draws on frontman James Graham’s personal turmoil, including his mother’s early‑onset dementia and subsequent death, delivering...
IBM Quantum Computer Accurately Simulates Real Magnetic Materials
IBM announced that its 127‑qubit quantum processor successfully simulated the magnetic properties of real‑world materials, achieving 99% fidelity compared with laboratory measurements. The experiment reproduced the behavior of iron oxide at room temperature, a benchmark previously out of reach for...
Agrivoltaics for Turnips
Researchers at the University of Western Ontario tested 13 photovoltaic modules, including semi‑transparent cadmium telluride (CdTe) and low‑transparency crystalline silicon (c‑Si), in field‑scale agrivoltaic trials with turnips. The 60 % transparent CdTe panel delivered the highest fresh root weight (176.5 g) and...
When Love Becomes a Sacred, Unheld Whisper
Thursday Poem: Have you ever loved someone so deeply you almost whisper their name to God then stop because you are not sure if you are asking for them or asking to be released Has it been love if it lives more in your spirit...
The Top 7 Questions Advisor Coaches Use to Help You (and Why They Change Everything)
Top advisor coaches use a seven‑question framework to unlock growth, clarity, and accountability for financial advisors. The questions surface unexpected wins, eliminate low‑impact tasks, and challenge comfort zones while addressing bottlenecks, over‑delivery, and personal development. Each prompt includes actionable homework...
Girl, 9, Gets to Play Mozart’s Half-Size Violin
Freya Chen, a 9‑year‑old student in Juilliard’s Pre‑College program, was granted the rare opportunity to perform on Mozart’s half‑size violin, a historic instrument from the International Mozarteum Foundation currently exhibited at New York’s Morgan Library and Museum. The violin, once...
Nutrients, Not Empty Calories, Drive Athletic Performance
I see a lot of athletes chasing calories because they were told '"just eat more", but not prioritizing nutrient dense foods. Calories provide energy but nutrients determine how well you perform, recover, and adapt. If you want strength, speed, and endurance, you...
Explaining the Wide Gap Between Country Stars and Everyone Else
Luminate’s 2025 Year‑End Music Report applied the Gini coefficient to streaming data, showing country music as the most top‑heavy genre with a 0.79 score, followed by pop at 0.75. Electronic/Dance recorded the lowest Gini at 0.54, indicating a more even...
Vagus Nerve Stimulation Shows Promise as a Way to Counter Alzheimer’s Disease- and Age-Related Memory Loss
Researchers are investigating vagus nerve stimulation (VNS) as a way to preserve the health of the locus coeruleus, a tiny brainstem region where tau protein first accumulates and predicts Alzheimer’s disease. The locus coeruleus produces norepinephrine, essential for sleep, attention,...
Live Journal Club Check-In
Emily P. Freeman’s fourth Journal Club check‑in recaps the four journals she relies on daily, emphasizing how each supports her personal productivity and reflection. The post dives deeper into her use of *The Next Right Thing Guided Journal*, spotlighting the...
Success Now Depends on Capability, Not Job Title
Hot take: I think we are moving from a world defined by roles to a world defined by capability. The old labels still exist, but they are getting less useful. Marketer. Developer. Designer. Strategist. What matters more is whether you can think clearly,...
New Big Ticket Episode Features Star‑studded Trailer for April Release
Zendaya. Robert Pattinson. Alana Haim. Mamoudou Athie. It’s a new episode of @Fandango’s Big Ticket, live now. Here’s a clip. In theaters April 3. https://t.co/Kvhfntn06u
Juni Habel Shares New Single “Pearl Cloud Song”
Norwegian singer‑songwriter Juni Habel has issued the instrumental single “Pearl Cloud Song” from her upcoming album Evergreen In Your Mind, out April 10 on Basin Rock. The four‑minute‑plus track blends steel‑string guitar, Herman Wildhagen’s pedal steel and co‑producer Stian Skaaden’s subtle...
Match Athlete Speed to Zones, Ditch Mileage Metrics
If you know your athletes, and you know how fast they should be going in each zone, they are one and the same.
Finding Joy in Silly Morning Moments Together
Drove my daughter to school this morning mostly in silence until we saw a lady speed walking, just flailing her arms around, looking a bit silly. We both looked at each other and chucked. Me: Nice technique. 14: You go, Queen. Love our...
"Masterpiece" Thriller One Battle After Another Is Finally Available to Stream in the UK
One Battle After Another, the Leonardo DiCaprio‑led thriller that swept six Oscars, is now streaming in the UK on HBO Max, Sky Cinema and NOW. The film, directed by Paul Thomas Anderson and adapted from Thomas Pynchon’s novel Vineland, boasts a 94%...
We Plan Weekends, Not Our Futures—Change Needed
I'm absolutely blown away by the amount of people who spend more time planning their weekend than planning their next decade. Two hours choosing a restaurant Zero minutes designing their life And wonder why nothing changes...
Break the Fitness Fad Cycle for Lasting Sustainability
Fitness is a carousel of recycling fads, the key is exiting the cycling and finding something meaningfully sustainable.
London Food Icons Morley’s and Roti King Are Teaming up for a Game-Changing Collab
London’s iconic fried‑chicken chain Morley’s has partnered with Malaysian eatery Roti King to launch a limited‑time pop‑up called Bossman Mamak in Brixton Village from April 9 to April 12. The collaboration will showcase four hybrid dishes that marry Morley’s signature...
Under the Leadership of Prime Minister, India Will Achieve Global Leadership in 6G: Scindia
Union Minister Jyotiraditya Scindia told Parliament that India is accelerating toward global 6G leadership under Prime Minister Narendra Modi. The newly operational Anusandhan National Research Foundation (ANRF) will mobilise roughly $6 billion in funding through 2028, including a $1.7 billion central budget...