How To: Measure Simpson's Biplane Accurately
Aram K.’s latest post walks clinicians through the step‑by‑step process for measuring left‑ventricular ejection fraction using the Simpson’s biplane method on 2D echocardiography. It stresses acquiring both apical four‑chamber and two‑chamber views, precise endocardial tracing at end‑systole and end‑diastole, and optimal machine settings to avoid foreshortening. The guide also highlights common pitfalls, reproducibility tips, and when to cross‑check results with three‑dimensional echo. By standardizing these techniques, the article aims to improve EF accuracy across cardiac labs.
First National Book Ban Targets Trans Youth, Act Now
I wrote about the first national book banning bill, which effectively seeks to erase trans people. At the end I include a link to let your reps know that you oppose this bill and all it stands for. https://lithub.com/why-we-must-fight-to-stop-hr-7661-before-it-destroys-the-lives-of-american-children/
Carson Foster Flashes Strong Breaststroke Performance at Pro Series
Carson Foster posted a 2:11.62 finish in the 200‑meter breaststroke at the USA Swimming Pro Series stop in Westmont, Illinois, earning fourth place behind teammate Leon Marchand. The swim marked a personal best by nearly three seconds, improving on his...
At CNBC Cures, Becky Quick Leads Clarion Call for Rare Disease Research
The CNBC Cures Summit opened with Becky Quick urging families and innovators to accelerate rare‑disease research. Speakers highlighted a widening gap between rapid scientific breakthroughs—gene therapies, AI‑driven diagnostics, and modular “nodal biology”—and an aging regulatory framework. Leaders from Biogen, the...
Six Books to Read About Iran
The Economist highlights six essential books that explore Iran’s tumultuous century‑long journey from revolution to its current geopolitical prominence. The list mixes histories, memoirs, and investigative reportage, offering readers insight into the Islamic Republic’s political, cultural, and economic evolution. By...
Triumph of the Toons: How Animation Came to Rule the Box Office
Animation has become the dominant force at the global box office, eclipsing many live‑action franchises. Disney‑Pixar’s latest release, “Hoppers,” showcases a breakthrough technology that lets a teen’s consciousness inhabit a robotic beaver, merging sci‑fi concepts with environmental storytelling. The film’s...
CottonConnect Consults on New Standard
London‑based social enterprise CottonConnect has released a draft Version 1.0 of its REEL Chain of Custody (CoC) Standard for public consultation. The standard seeks to extend the REEL cotton programme’s traceability from the gin through to finished textile products, offering a...
Nothing Breaks Our Little Hearts In Two
The reviews spotlight Gena’s “Circlez,” praised for its meticulously calibrated mix that blends warm organ tones, precise percussion, and immersive spatial effects. Bebe Rexha’s “Çike Çike” draws heavily on early‑90s house and Madonna‑era pop while feeling contemporary, reflecting a streaming‑driven “flat‑time”...
FDA’s Hoeg Reportedly Trying To Hire Friend, Fellow Antidepressant Skeptic
The FDA’s acting CDER director Tracy Beth Høeg is reportedly moving to hire Adam Urato, a maternal‑fetal specialist known for his skepticism of antidepressants during pregnancy. Urato has publicly called for stronger warnings on SSRIs and has filed a citizen...
The Smart Kids Who Got Labeled “Problem”
In this episode of the Liquid Lunch Project, host Matthew Armahan interviews dyslexia researcher and entrepreneur Russell Van Brocklin, who shares his personal journey from being labeled a low‑reading student to developing a scalable, low‑cost intervention that teaches writing first...
Book of Churches’ Self Titled: A 48-Hour Blueprint of the Soul
Felix Mackenzie-Barrow’s debut solo album Book of Churches was recorded in a frantic 48‑hour session using only a couple of microphones and a cell phone. The resulting collection feels like a raw demo, emphasizing first‑thought urgency and stripped‑back arrangements. Critics...
How Early Stress Shapes the Developing Brain
Decades of developmental research, highlighted by Professor Megan Gunnar’s work, show that stress in the first years of life reshapes brain circuitry and later behavior. Sensitive periods make early experiences especially potent, with misbehavior often serving as a visible cue...
PepGen’s Mid-Stage Myotonic Dystrophy Study Hit With ‘Surprise’ Pause
PepGen’s Phase 2 FREEDOM2 trial in myotonic dystrophy type 1 received a partial FDA clinical hold due to concerns over a sub‑chronic mouse study that showed blood‑pressure changes. The agency did not question the Phase 1 human data, and the company continues dosing...
Punjab Attracts US $ 82 Million Textile Investment as Yarn Maker Ganga Acrowools Expands Operations
Ganga Acrowools Limited announced a Rs 750 crore (US $81.85 million) expansion in Punjab, marking the state’s largest recent textile investment. The project will add more than 1,500 jobs to the company’s existing 5,600‑strong workforce and focus on specialised yarns for knitting, weaving, carpets...
Call for Textile Park in Shivamogga Ahead of Karnataka Budget
Chairman Chetan K. Gowda of Karnataka State Textile Infrastructure Development Corporation has pressed the state government to announce a dedicated textile park in Shivamogga during the upcoming budget. He met Chief Minister Siddaramaiah on March 2, submitting a memorandum that highlights...
D2C Channels Growing Faster Than E-Commerce Marketplaces in India: Report
McKinsey’s latest report finds India’s direct‑to‑consumer (D2C) market, now worth $10‑11 billion, is set to explode to $55‑60 billion by 2030, growing at a 38% CAGR. This outpaces traditional e‑commerce marketplaces, whose sales are expected to reach only $100 billion with a 10‑12%...
Dramatic Cuts in Nova Scotia Budget Will Greatly Impact Publishers and Writers
The Nova Scotia government’s 2026‑2027 budget proposes a 30% reduction in arts, culture and heritage funding, a $14 million cut to discretionary spending, and the elimination or reduction of more than 70 grant programs worth over $130 million. A coalition of national...
Blackberrys Brings Onboard Apparel Industry Veteran Sartaj Singh Mehta
Blackberrys, the Indian menswear label, has appointed Sartaj Singh Mehta to its senior team, tapping a veteran with nearly three decades in fashion and lifestyle. Mehta most recently served as Senior Director of Product and Design at Pepe Jeans London,...
The Untrustworthy Speaker
Louise Glück’s poem “The Untrustworthy Speaker,” originally published in her 1990 collection Ararat, resurfaced on a Substack literary blog. The work delves into the speaker’s self‑doubt, portraying passion as a barrier to trust and linking emotional wounds to mental distortion....
Your DNA Isn’t Your Destiny: The Science of Epigenetics and Experience
Epigenetics studies how environmental experiences modify gene expression without altering DNA sequences. A landmark McGill study demonstrated that maternal behavior in rats can imprint lasting epigenetic changes on offspring brain circuitry. The research links stress, pregnancy, and parenting to measurable...
With New Competition, IFLA Is Looking For the Next Masters of Library Science…Fiction
IFLA is celebrating its centennial by launching the Li‑Sci‑Fi short‑story competition, inviting librarians to imagine the future of their profession. The contest features two categories—flash (up to 1,000 words) and standard (1,001‑2,500 words)—with submissions due September 1 2026. Celebrity author Mary Robinette Kowal...
‘Dirty Work’
S. Yizhar’s 1949 novella Khirbet Khizeh dramatizes the forced expulsion and burning of a Palestinian village during Israel’s 1948 war, drawing on his own experience as a Givati Brigade officer. The real village, Khirbet al‑Khisas, was identified in 1978, confirming the author’s claim...
This Very Posh Belgian Chocolatier Is Opening a Flagship Store in Central London This Month, with a Macaron Carousel...
Belgian chocolatier Pierre Marcolini will launch its flagship store on Regent Street, London, on March 27, following a soft‑launch event on March 25‑26. The new West End location will showcase exclusive flavours such as strawberries‑and‑cream, a dedicated hot‑chocolate "grand cru"...
God’s Impertinent Prophets
Naomi Baker’s *Voices of Thunder* uncovers a hidden wave of seventeenth‑century English women who wrote, preached, and staged prophetic acts amid religious turmoil. From blood‑stained Quaker protests at St. Paul’s to the radical visions of Seekers, Ranters and Levellers, these dissenters...
All of Us Yahoos
Dan Sperrin’s State of Ridicule offers an 800‑page, Roman‑to‑2010s survey of English satire, arguing that satire is fundamentally political and serves as a tool for interpreting power. The book adopts a “longue durée” label but actually traces decade‑by‑decade political events, pairing each...
Your Daily Rhythm Matters More Than You Think
The article argues that modern indoor lifestyles and constant connectivity disrupt our innate circadian rhythm, leading to heightened stress and poorer sleep. It contrasts city living—characterized by artificial light and fragmented rest—with a rural lifestyle that embraces daylight, physical activity,...
Use Principles Over Formulas to Structure Your Story
Try searching for “how to structure a story” and you'll get a panoply of instructions: Hero’s Journey Three-act structure Save the Cat Snowflake method Freytag’s Pyramid Fichtean Curve What do you do with them? Tiffany Yates Martin advises: https://janefriedman.com/base-your-story-structure-on-principles-not-systems/
A Most Particular Life
The early modern diary of Swiss physician Felix Platter, chronicling his teenage journey from Basel to Montpellier in 1552, has been reissued in a new paperback edition. The English translation, originally produced by Seán Jennett in 1961, now features a foreword...
I Took a Solo Railway Trip Across the Largest Landlocked Country in the World
Writer Kate Bettes embarks on a 26‑hour, 2,485‑km train journey from Almaty to Oskemen, traversing Kazakhstan’s vast steppe on a Soviet‑era platzkart carriage. The trip showcases the country’s 16,000‑km rail network, communal travel culture, and lingering Russian influence. Along the...
The Darkness From the Darkness
Darcey Steinke’s 2026 memoir *This Is the Door: The Body, Pain, and Faith* examines how chronic physical ailments, especially debilitating back pain, shape spiritual and existential outlooks. Drawing on personal anecdotes, interviews with artists, writers, and scholars, the book maps...
New Leadership Structure Set for Ferrero Group
Ferrero Group unveiled a revamped leadership structure aimed at accelerating global growth and innovation. Giovanni Ferrero will remain Executive Chairman while a newly created Chief Operating Officer role will be filled by longtime executive Pietro Ferrero. The reorganization consolidates the...
Scales in Comparison: Matter and Shape 2026’s Theme Spotlights Industry Giants and Artisans Alike
Matter and Shape 2026, a Paris design salon, spotlights the theme of scale, juxtaposing industry giants that account for roughly 15 % of the €470 billion global furniture market with boutique studios whose collectible pieces are achieving record prices, such as a...
Whitewater Kayak Review: Pyranha ReactR
In May 2024 Pyranha released the ReactR, a medium‑size whitewater kayak that combines a quarter‑slice stern with a high‑volume hull. The boat features the new Elite outfitting—extra foam padding, adjustable thigh grips, and a pulley‑based strap system—for enhanced comfort and...
Knee Pain Signals Years of Inactivity, Not Surgery Need
The hardest conversation I have in my office isn't about surgery. It's about time. A 58-year-old sat across from me with knee pain. She’s otherwise healthy, but menopause has been rough on her. Her MRI shows some cartilage changes — age-appropriate,...
LA Art Gold Rush Ends, Future Market Uncertain
The Art World’s Los Angeles Gold Rush Is Over. What Comes Next? My latest column on @artnet @artdetective @friezeofficial #artmarket https://t.co/E8tNfMFfwX
Joanna Barker’s A Love Most Daring Is Strong Regency Mystery
Joanna Barker’s third Bow Street novel, A Love Most Daring, launches March 3, 2026 as a paperback in Shadow Mountain’s Proper Romance line. The Regency‑set story follows Beatrice Lacey, a scandal‑tainted society miss, who teams with Bow Street officer Alexander...
Prioritizing Donut Debate Over School PE Mandates
RFK/MAHA: dunkin donuts is the enemy... Also RFK/MAHA: still no mandatory daily physical education requirement in public schools... https://t.co/DxhEGNvCs0
How to Walk Through a Cathedral
Visitors often rush cathedrals, missing the layered experience designed by medieval builders. The author argues the journey should begin with the façade, which functions as an introductory narrative, before moving inside to appreciate height, light, sound, and geometry. Examples from...
Bent‑over Rows Are Fading—
We don’t talk about the disappearance of the bent over row enough. 5 x 5 lunchtime today. https://t.co/SwES1NaMQh
Master Sodium Use: Decision Tree Webinar Guide
Join the webinar and walk away with a clearer understanding and a no-nonsense decision tree to guide when to use sodium, how to dose it, and when not to bother. Secure your spot: https://t.co/qvjELFGgfZ https://t.co/R3SCs3n4vx
Snake Eyes’ Cash Rich: Unleashing Calculated Chaos
Snake Eyes have finally released their long‑awaited album Cash Rich on Alcopop! Records after five years of careful curation. The 12‑track record showcases a lo‑fi fuzz‑driven sound mixed with heavy distortion and occasional acoustic moments, reflecting the band’s gear‑obsessed production...
Circular RNA MT-RNR2 in Mitochondrial Function and Aging
Researchers identified mitochondrial circular RNA MT‑RNR2 as abundant in young cells but depleted in older individuals and senescent fibroblasts. The RNA‑binding protein GRSF1 binds both linear and circular MT‑RNR2, linking it to TCA‑cycle enzymes and glucose metabolism. Loss of GRSF1...
Enhancing Mitochondrial Function Improves Memory in Flies and Mice
Researchers discovered that boosting mitochondrial metabolism in neurons enhances long‑term memory formation in both fruit flies and mice. By reducing expression of the mitochondrial calcium exporter Letm1, calcium accumulates in the mitochondrial matrix, over‑activating metabolic pathways and increasing ATP production...
How to Get Out of a Slump 🤷♀️
The Good Trade article "How to get out of a slump" offers practical steps for breaking personal inertia, blending mindset shifts with tangible lifestyle tweaks like vegan street tacos, a productivity podcast, and ergonomic pillows. It emphasizes diagnosing the slump’s...
Maya Hawke Announces Fourth Album ‘Maitreya Corso’ and Releases Lead Single
Maya Hawke, known for her roles in "Stranger Things" and "The Hunger Games," announced her fourth studio album, Maitreya Corso, slated for release on May 1. The lead single, "Devil You Know," showcases stripped‑back folk influences and reflects her desire...
Finding Our Way
The author recounts a journey from alcohol‑driven darkness in Juneau to a life anchored in Zen practice and recovery. By immersing in the San Francisco Zen Center, he discovers that brokenness, when faced, becomes a source of healing, illustrated through...
ŌURA Acquires Doublepoint to Expand AI-Driven Interaction Capabilities
Oura announced the acquisition of Doublepoint, a Helsinki‑based AI gesture‑recognition startup, to embed natural, biometric interactions into its wearable platform. The deal brings Doublepoint’s four founders and AI architects into Oura’s R&D, reinforcing a roadmap that blends voice and gesture...
The Beginner Strongman Program by Matt Mills
Matt Mills, a veteran strongman coach, released a 16‑week Beginner Strongman Program aimed at newcomers and first‑time competitors. The plan features basic barbell lifts, event‑specific drills, and accessory work, with a mid‑program deload and optional post‑program deload for recovery. Progression...
Happiness Break: A Meditation For Connecting In Polarized Times
The Science of Happiness podcast released a "Happiness Break" episode featuring author Scott Shigeoka leading a guided visualization that trains listeners to approach contentious conversations with curiosity. The practice combines breathwork, mental rehearsal, and vivid imagination to reframe tense moments,...