#393 ‒ AMA #85: A Guide to Medications and Supplements: Determining What to Take, What to Skip, and How to...
In this AMA, Peter Attia explains how to evaluate medications and supplements by first precisely defining a health problem with measurable metrics, targets, and timelines, rather than starting with a desired outcome. He stresses that the intended purpose of an intervention dictates the level of evidence and risk tolerance required, and that baseline risk and absolute versus relative risk reductions are crucial for judging real-world benefit. Attia also outlines how to weigh side effects, cost, inconvenience, and opportunity cost, and provides a practical framework for self‑experiments and periodic reevaluation, highlighting the high failure rate of many over‑the‑counter supplements and naming a few that offer a favorable risk‑reward profile.
#393 ‒ AMA #85: A Guide to Medications and Supplements: Determining What to Take, What to Skip, and How to...
In this 13‑minute AMA preview, Dr. Peter Atiyah explains how to choose medications and supplements by first defining a concrete health problem—specific metric, threshold, and timeline—rather than vague goals like “more energy.” He categorizes interventions into four "jobs"—disease treatment, symptom...
What Your Negative Emotions Are Trying to Tell You
In this episode of The Happiness Lab, host Laurie Santos talks with Harvard psychologist Susan David about how to handle negative emotions more skillfully. David explains that people typically either bottle up feelings or brood over them, both of which...
Paper Airplane Poet by Sheri Singerling (Audio)
In this episode of ClarksWorld Magazine, host Kate Baker reads Sheri Singerling’s short story “Paper Airplane Poet,” a companion piece to Singerling’s novel *Blessed is the Rot* from the Bit Trilogy. The narrative follows Tilly, a young woman confronting a...
Leonidas-Romanos Davranoglou: The Last Hellenes and the Children of the Yamnaya
In this episode of the Unsupervised Learning Podcast, host Razib Khan talks with Leonidas‑Romanos Davranoglu, a biologist‑historian who studies ancient DNA, about two of his recent papers on the genetic continuity of the Maniot Greeks and the ancient DNA of...
Paige Lewis on CANON
In this episode of Poured Over, bookseller Jen Nasiri chats with poet‑novelist Paige Lewis about Lewis’s debut novel *Canon*, a genre‑bending work that follows two parallel heroes—one sent by God, the other defying divine will—on a quest to kill the...
Leena Nair and Matthieu Blazy on Creativity and the Power of the Human Hand
In this episode, Imran Ahmed talks with Chanel CEO Leena Nair and creative director Matthieu Blazy about the resurgence of Chanel, driven by a blend of bold creative vision and deep operational investment. Nair, a former Unilever executive, emphasizes the...
Jonathan Tepper on Grief, Addiction, Empathy, and Growing Up Missionary
In this episode, host Frank Schaefer talks with Jonathan Tepper—chief investment officer at Prevac Capital and author of the memoir *Shooting Up*—about his unconventional upbringing in a Spanish missionary family that ran a heroin‑addiction rehab, the profound losses he endured,...
791: DAFs: 2026 Benchmark Report & Dashboards As Functional Powerhouses – Tony Martignetti Nonprofit Radio
In this episode, Tony Martinetti interviews Karen Kirchhoff of K2D Strategies and Mitch Stein of Chariot about the 2026 Donor‑Advised Fund (DAF) Benchmark Report, revealing rapid growth in DAF giving—30% year‑over‑year increase in 2024—while traditional individual donations slipped. They explain...
TLDR Jasper Johns | Flag
In this TLDR mini‑episode, host Kyle Wood outlines Jasper Johns’s life and artistic breakthrough, focusing on his iconic 1954‑55 "Flag" painting. He explains how a vivid dream spurred Johns to abandon abstract expressionism, destroy his early work, and adopt the...
'Obsession' Compulsion and 'Shrek'-Cavation
In this lively episode of the Box Office Podcast, host Scott Mendelson and a rotating panel of film analysts—including Jeremy Fuster, Lisa Layman, Max Deering, and guest Randy Jones—delve into the enduring appeal of the Shrek franchise, dissecting favorite scenes,...
The Next Era of Healthcare Is Personal
In this episode, McKinsey’s Eric Kutcher talks with Moderna CEO Stéphane Bancel about how mRNA technology and AI are reshaping healthcare from rapid vaccine development to truly personalized medicines. Bancel explains that mRNA is an "information molecule" that can be programmed...
You’re Not Broken: Why You People-Please, Feel Anxious, & Never Feel Good Enough – and How to Heal
In this episode, Mel Robbins talks with therapist and bestselling author Kelly McDaniel about "mother hunger," an invisible childhood wound stemming from unmet needs for nurturing, protection, and guidance. McDaniel explains how this deficit fuels adult issues like people‑pleasing, perfectionism,...
Staying Human with Dr. Vivek Murthy
In this brief 1‑hour‑23‑minute episode, Dr. Vivek Murthy, the U.S. Surgeon General, explores what it takes to lead a life of lasting peace, joy, and love. He argues that technology and modern pressures are eroding core human qualities—relationships, compassion, and...
TRIBE With Sebastian Junger - Episode 4 - Richard Wrangham
In this episode, host Sebastian Junger talks with Harvard evolutionary biologist Richard Wrangham about the stark differences between chimpanzee and bonobo societies and what they reveal about human violence and cooperation. Wrangham explains how male chimpanzees engage in organized, often...
Why Speed Is a Byproduct, Not the Goal (with Dawna Ballard)
In this episode, organizational communication professor Dawna Ballard explains her research on chronemics—the study of time in human interaction—and how deliberately slowing down can actually accelerate outcomes. She illustrates this with the Children’s Advocacy Centers model, where regular, slower-paced meetings...
Beyond Senolytics: Senoadaptive Drugs & Clinical Data on GPX4 Modulation (Dr. Marco Quarta, Rubedo)
In this episode, Dr. Marco Quarta, co‑founder and CSO of Rubedo Life Sciences, discusses the company’s breakthrough first‑in‑class GPX4‑modulating drug RLS1496, which has just reported preliminary Phase 1 basket‑trial data across multiple skin indications. He explains how Rubedo’s AI‑enabled single‑cell multi‑omics...
Turning Abandoned Drugs Into Breakthroughs
In this episode, PureTech Health president Eric Alenko explains the company’s hub‑and‑spoke model for rescuing abandoned therapeutics, focusing on systematic identification of unmet needs, validation of human pharmacology, and solving the specific liabilities that halted development. He details how PureTech...
He's Spent 25 Years Using Earth-Based Traditions to Turn Boys Into Men. Here's What He Knows.
In this episode of Front Row Dads, host Jon Broman sits with Tim Corcoran, founder of Twin Eagles Wilderness School, to explore how nature‑based rites of passage can transform boys into men. Tim shares his personal journey—from a disconnected childhood...
3 Brain Tricks For Expanding Attention and Handling Stress
In this solo episode of the Sunlight Tax Podcast, host Hannah Cole shares three brain‑reset strategies for expanding attention and managing stress: taking a purposeful pause by clearing non‑essential tasks, using structured co‑working sessions as accountability to tackle dreaded work,...
Part 3: The Art and Science of Peaking
In this third installment of their "Peaking" series, coaches Steve Magnus and John Marcus dissect the elusive concept of peaking, arguing that it’s less about a magical performance boost and more about eradicating fatigue while preserving fitness. They emphasize the...
Gen Z and Mental Health with Dr. Mary Collins
In this episode of the HR Chat Show, host Bill Banham talks with Dr. Mary Collins, a chartered psychologist and senior leadership coach, about the unique challenges and strengths of Gen Z in the workplace. They discuss how AI is...
How to Resist the Attention Economy — with Bill Burnett and Dave Evans
In this episode, Stanford educators Bill Burnett and Dave Evans discuss how the attention economy—driven by billion‑dollar tech firms—saps our focus and fuels doom‑scrolling. They argue that the antidote isn’t simply unplugging, but designing personal habits and environments that are...
The Lagniappe Sessions :: Resavoir & Matt Gold
The episode titled "The Lagniappe Sessions :: Resavoir & Matt Gold" appears to consist primarily of brief interjections and a thank‑you message, with no discernible discussion topics, guest insights, or substantive content. No clear themes, takeaways, or expert perspectives are...
Philosophy of Physics Meets Quantum Engineering with Elise Crull
In this episode, host Sebastian Hassinger talks with Elise Crull, an associate professor of philosophy of physics, about the growing relevance of philosophical analysis to quantum engineering. Crull explains how the rise of quantum computing forces physicists to confront interpretive...
UK Politics, AI Boom and Market Resilience
In this episode, Anna MacDonald and Matt Britsman dissect the fallout from the recent UK local elections, noting rising gilt yields and the potential for higher risk premiums as political uncertainty looms. They then shift to global market dynamics, highlighting...
Walter De Maria | The Lightning Field (Encore)
In this episode of Who Arted?, host Kyle Wood chats with Tim Bogatz of Art Ed Radio about minimalist artist Walter De Maria, focusing on his iconic work, The Lightning Field. They explore De Maria’s eclectic background—drummer for an early...
Start Where You Are: #1 Orthopedic Surgeon’s Proven Protocol to Feel Stronger & Look Younger in Weeks
In this episode, Mel Robbins talks with Dr. Vonda Wright, a double‑board‑certified orthopedic surgeon and longevity researcher, about how women can prevent the frailty they fear in aging. Dr. Wright shares that the body can respond positively to small, consistent...
The Hidden Beliefs That Shape Your Happiness with Shawn Achor
In this episode of The Happiness Lab, host Dr. Laurie Santos talks with happiness researcher Shawn Achor about the hidden beliefs that shape our well‑being. Achor explains that beliefs act as a lens that influences everything from academic performance to...
783: How to Take Back Your Evenings, with Guy Winch
In this episode, psychologist and author Guy Winch discusses how work can hijack our evenings through autopilot behavior and rumination, explaining why stress often resurfaces after hours. He outlines practical strategies to break the cycle, such as recognizing and labeling...
Can We Reverse Aging?
The episode explores the rapidly advancing field of longevity science, focusing on cellular rejuvenation techniques that aim to reverse aging at the cellular level. It traces the discovery of Yamanaka factors, their initial cancer risks, and subsequent refinements by researchers...
Kate Bowler Wants You to Know Joy Is Still Yours
In this episode, author and cancer survivor Kate Bowler explores the paradox of feeling a deep, almost mystical sense of joy and wholeness even amid profound suffering. She reflects on the fleeting moments of peace she experienced right after her...
Jon Krakauer on INTO THIN AIR
In this episode of Poured Over, host Miwa Messer interviews author Jon Krakauer about his seminal book *Into Thin Air* and the broader arc of his career. Krakauer reflects on the 1996 Everest disaster, the rise of commercial expeditions, the...
If You’re Feeling Stuck in Life, Listen to This
In this episode, Mel Robbins tackles the universal feeling of being stuck, explaining that it’s a signal of untapped potential rather than a personal flaw. She outlines three "traps" that keep people immobilized, focusing first on the most common: not...
Redefining What Efficiency Means in the Age of AI
In this episode, neuroscientist and physician Mitou Steroni explains that true efficiency in the AI era means prioritizing the quality of human output over sheer quantity. She argues that generative AI handles repetitive tasks, freeing brains to engage in deeper,...
The Architecture of Artificial Desire: Schopenhauer and the Algorithm of Envy
In this episode, host explores the philosophical roots of modern consumer desire by linking Arthur Schopenhauer’s concept of the ‘will’ to today’s algorithm-driven envy on social media. The discussion illustrates how curated feeds act like a pawn‑shop window, constantly presenting...
CGI 2026 Meditation #2: Visualization
In this 12‑minute guided meditation, the Clock Global Institute host leads listeners through a visualization exercise that moves from a calm breathing foundation to an imagined walk toward the ocean, engaging all five senses. The practice emphasizes mindful awareness of...
PSP 470: Helping Kids with Just Right OCD
In this episode of the AT Parenting Survival Podcast, child therapist Natasha Daniels explains the often‑overlooked "Just Right" subtype of OCD, emphasizing that it is driven by a feeling of incompleteness rather than fear. She outlines how this theme can...
The Leadership Skills That Make Transformation Stick
In this episode, Adi Ignatius and Alison Beard interview Julia Darr, Managing Director and Partner at Boston Consulting Group and founder of BCG’s Behavioral Science Lab, about why more than 70% of organizational transformations fail. Darr explains that failures stem...
Coaching Successfully Series Part 2: Defining Your Training Approach
In this second episode of the Coaching Successfully series, Steve Magnus and Jonathan Marcus discuss the pitfalls of both overly vague and overly rigid training philosophies, emphasizing the need for a balanced, adaptable approach. They explore how environmental factors—such as...
Get Ready for a Reading Retreat
In this episode of What Should I Read Next?, host Anne Bogle and Modern Mrs. Darcy Book Club community manager Ginger Horton unveil the 15th edition of their Summer Reading Guide, themed "Reading Retreat," which drops on May 14. They...
Behind Kalshi’s $22B Rise: Betting on Addiction with Dr. Rian Kabir
In this episode of Lifers, host Christina Farr talks with psychiatrist and medical AI specialist Dr. Rian Kabir about the rapid rise of online prediction marketplace Kalshi, now valued at $22 billion. Dr. Kabir explains that, despite legal arguments framing Kalshi...
Tested and Proven Audio 544
Daily Devotional for Women published its latest episode, "Tested and Proven Audio 544," as part of its evening devotional series. The audio piece is delivered through Substack and is available exclusively to paying subscribers. Listeners can stream the episode via...
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The Lagniappe Sessions :: The Sleeves
In this experimental episode of The Lagniappe Sessions, the band The Sleeves perform a stream-of-consciousness lyrical piece that blends surreal imagery with themes of anxiety, longing, and the search for escape. The recurring motif of a mysterious train heading to...
Chocolate-Olive Oil Spread
In this episode, host (presumably the author of The Great Book of Chocolate) teams up with longtime food blogger Deb Perlman of Smitten Kitchen to create a chocolate‑olive oil spread for her upcoming chocolate cookbook. They walk through the recipe—sifting...
Thinking Inside the Box (with David Epstein)
In this EconTalk episode, author David Epstein discusses his new book *Inside the Box: How Constraints Make Us Better*, arguing that modern life overvalues unrestricted freedom while undervaluing the creative boost that smart boundaries provide. He illustrates this with historical...
Lead Better - The Leader’s Antidote for Worry
In this episode of Lead Better, hosts Scott Baker and Mikey explore how leaders can transform worry into productive action. They discuss the psychological distinction between threat monitoring and agency, illustrating the point with surfer Shane Dorian’s rapid return to...
Hrishikesh Hirway and the Perfect Song Myth
In this episode, host Jeremy chats with musician and creator Hrishikesh Hirway, best known for the acclaimed podcast Song Exploder. They explore Hirway's journey from his early 1 AM Radio projects to feeling stuck, which led him to launch Song...
864: Investigating How Brain Inflammation May Contribute to Compulsivity - Dr. Laura Bradfield
In this episode, Dr. Laura Bradfield, a senior lecturer in psychology at the University of Sydney, discusses her research on how neuroinflammation in the brain may drive compulsive behaviors across disorders such as OCD, substance use, Parkinson's and Huntington's disease....