Episode 1,001: My AI Journey So Far
In this milestone episode, the host reflects on the evolution of the show and their personal AI journey, contrasting early experiences with current developments. They highlight what has fundamentally changed in AI tools and practices, as well as enduring principles that remain relevant. The discussion points toward emerging opportunities and potential breakthroughs that stem from both the new advancements and the timeless insights gathered over the show's history.
Post‑generation Editing Makes AI Tools Far More Enjoyable
Editing things after AI generates them was very needed. Makes @lovart_ai much more fun to use.
Front Row with BioCentury: Inside the Turbulent Ride of Cell and Gene Therapy
Cell and gene therapy continues to attract attention despite a recent wave of setbacks that have slowed commercial momentum. Manufacturing complexities, heightened regulatory scrutiny, and pricing debates are creating a turbulent environment for developers. Nevertheless, breakthrough scientific data and expanding...
Why the Next AI Frontier Is Phone Calls, with Beside CEO Maxime Germain
In this episode, the hosts discuss the latest AI industry turbulence—including OpenAI’s alarm over Google’s Gemini and talent wars between Apple and Meta—before interviewing Maxime Germain, CEO of Beside, the AI-powered receptionist handling 2.5 million calls monthly for 20,000 businesses. Germain...
Enterprises Overwhelmed by, and Attracted to, AI Technology
OpenAI’s rapid rollout of GPT‑5.2, just weeks after GPT‑5.1, highlights a widening gap between AI model releases and enterprise adoption. Companies at the AI summit reported feeling overwhelmed by the flood of agentic AI tools from vendors like Microsoft, AWS,...
Science Spotlight: Chinese Researchers Advance PROTAC Design
Chinese scientists have unveiled a next‑generation PROTAC scaffold that delivers oral bioavailability and heightened target selectivity. The platform successfully degrades previously undruggable proteins, including KRAS(G12C), and demonstrates tumor‑growth inhibition in mouse models. By integrating AI‑guided linker optimization, the researchers mitigated...
Google Tests On-Article AI Breakdown Panels
The episode explores Google's new AI-powered "breakdown panels" that appear within articles to automatically highlight key events, people, and data. It discusses how these panels aim to enhance reader comprehension while noting publishers' wariness about depending on machine-generated summaries for...
Clive Kinross, CEO of Propel Holdings, on Building a Profitable Fintech Lender with Just $4 Million
Clive Kinross, CEO and co‑founder of Propel Holdings, explains how his accounting background drove a disciplined, unit‑economics focus that enabled the fintech lender to become profitable from its early days with just $4 million in seed capital. He details Propel’s AI‑powered...
GPT-5.2 Is Here
The episode dissects OpenAI's new GPT‑5.2, highlighting its stronger reasoning stability, extended context handling, and real‑world productivity features for coding, spreadsheets, and presentations. Early benchmark data and tester feedback illustrate tangible performance gains, while the hosts discuss OpenAI's pivot toward...
News Alert: INE Sees Surge in Q4 Budget Shifts as Enterprises Embrace Hands-On Training for AI Roles
Enterprises are reallocating Q4 learning‑and‑development budgets toward hands‑on, performance‑based training as AI reshapes cybersecurity, cloud, and IT operations. INE reports a surge in demand for immersive labs, simulations, and AI‑adaptive pathways that promise faster competency and measurable ROI. The shift...
Apple Loses Contempt Appeal in Epic Case
Apple lost its appeal of the district‑court contempt order in the Epic Games antitrust case. The Ninth Circuit affirmed Judge Gonzalez Rogers’ finding that Apple deliberately violated a 2021 injunction by restricting external payment links and imposing a 27% fee....
More AI Agents Help Rarely; Benefits Depend on Task
Major new research from Google and MIT. "More agents is all you need" has become a mantra for AI developers. We know multi-agent systems can be effective, but we do this mostly based on heuristics. ... but this study (180 configs across OpenAI/Google/Anthropic...
75: A Woken Record
In this episode, hosts Kathy Campbell and Alex Cox examine the rollout of autonomous delivery robots in Chicago, exploring both the technological promise and the community backlash over sidewalk safety and accessibility. They discuss real‑world case studies—from a day in...
1X Struck a Deal to Send Its ‘Home’ Humanoids to Factories and Warehouses
Robotics firm 1X announced a strategic partnership with EQT to ship up to 10,000 Neo consumer‑grade humanoid robots to more than 300 EQT portfolio companies between 2026 and 2030. The Neo, originally marketed for home use at a $20,000 price...
Navigating AI: Insights From ProArch's Cloud Strategy Director
In this episode, host Jaeden Schafer talks with Jim Spignardo, ProArch's Director of Cloud Strategy and AI, about the rapid rise of AI tools like ChatGPT and how organizations can adopt them strategically. Jim emphasizes the need for robust AI...
Identity and Money: A Case Study
The episode examines Ireland’s 1966‑1976 bank strikes, showing how the economy survived without cash by relying on cheques, IOUs and locally‑issued substitutes backed by strong social capital. It highlights that reputation‑based identity networks—often mediated through pubs and community figures—enabled informal...
New York’s New Law Forces Advertisers to Say when They’re Using AI Avatars
New York Governor Kathy Hochul signed legislation requiring advertisers to clearly disclose the use of AI‑generated avatars in commercial spots. The law also mandates consent from heirs or executors before a deceased person’s likeness can be used for profit. Violations...
MIT Researchers Use AI to 'Speak' Objects Into Existence
MIT researchers have created a speech‑to‑reality system that turns spoken requests into physical objects by combining large‑language models, 3D generative AI, and robotic assembly of modular cubes. The platform generates a mesh, partitions it into buildable components, and directs a...
AI Trained in Space.
The episode explores the emerging frontier of space‑based AI and data infrastructure, highlighting Starcloud’s milestone of training the first large AI model in orbit and DARPA’s Phase 2 contract with BAE to develop autonomous space surveillance. Guest Jerome Hittle, CEO of...
AI Should Augment, Not Replace: Prioritize Human Skills
The biggest mistake leaders are making right now? Focusing only on AI automation. New AI roles are emerging but they aren't signals of replacement—they're signals of ✨human augmentation✨ and a fundamental shift from control to connection. 70% of employees see...
Top Tracking Issues We Help Our Clients With
NP Digital outlines the most common data‑tracking failures that undermine marketing ROI, from biased attribution and GA4 revenue gaps to consent‑management lapses and fragmented cross‑device IDs. The firm recommends a systematic audit, unified taxonomy, and integration of GA4 with a...
Key Triggers That Signal It's Time to Raise or Exit
We frequently get asked how a founder can tell when it's the best time to think about raising capital or making an exit. The truth is, it depends on a handful of factors. In this video, I walk through some...
CopilotKit v1.50 Brings AG-UI Agents Directly Into Your App With the New useAgent Hook
CopilotKit v1.50 rebuilds its frontend on the Agent User Interaction (AG‑UI) protocol and ships a new React hook, useAgent, that turns agent‑to‑UI communication into a single typed event stream. The hook subscribes to messages, streaming tokens, tool calls and shared state,...
GPT‑5.2 Boosts Reasoning, Yet Overwhelms with Verbosity
🚨 OpenAI has released GPT-5.2. I had early testing access (thank you, OAI team) and here is my honest take: 👍 On the upside, the thinking and problem-solving feel noticeably stronger. It gives much deeper explanations than I’m used to...
SaasRise CEO Mastermind Recaps for the Week of December 8-11, 2025
The SaaS Rise CEO Mastermind week of Dec 8‑11 tackled ten high‑impact growth challenges, from fake review mitigation to AI‑driven data scraping. Participants received actionable tactics such as temporary premium Trustpilot upgrades, swapping PDF lead magnets for direct sign‑ups, and building...
Most AI CRO Tools Miss Core Fundamentals
A lot of teams are trying new AI tools because the demos look smooth and the promise feels real. But when we evaluated each analyzer across the core dimensions of CRO, a surprising number scored zero. They failed on the fundamentals: Who is...
Disney Hits Google with Cease-and-Desist Claiming ‘Massive’ Copyright Infringement
Disney sent a cease‑and‑desist letter to Google, alleging massive copyright infringement by the company’s Gemini AI service, which it says reproduces and distributes protected characters at scale. The letter claims the AI‑generated images are branded with the Gemini logo, falsely...
AI-Driven Finance: MCP Bridges Data to Real Answers
The next era of finance won’t be dashboards and spreadsheets. It’s going to be AI sitting on top of clean, structured data and understanding how your business works. A few months back I got my hands on Maxio’s MCP (Model...
SAM-3 Runs on Gaming GPUs, Fuels Lightweight Models
Can SAM-3 run on a normal consumer GPU, or do you need massive compute and a billion-dollar data center? In this video, we break down the real answer. Spoiler: yes… and no. You’ll learn: ☑️Whether SAM-3 can run...
The Disney-OpenAI Tie-Up Has Huge Implications for Intellectual Property
Disney and OpenAI announced a three‑year partnership that will let ChatGPT and Sora users generate images and videos featuring more than 200 Disney characters, starting in early 2026. The agreement includes a joint steering committee to oversee how Disney’s intellectual...
Google Debuts ‘Disco,’ a Gemini-Powered Tool for Making Web Apps From Browser Tabs
Google unveiled Disco, an AI experiment powered by Gemini 3 that creates custom web applications—called GenTabs—from users' open browser tabs. The tool proactively suggests interactive apps tailored to browsing activity, such as study visualizations, meal plans, or travel itineraries, and allows...
Test‑time Adaptation Unlocks Fluid Intelligence, but AGI Still Distant
Back in 2019, ARC 1 had one goal: to focus the attention of AI researchers towards the biggest bottleneck on the way to generality, the ability to adapt to novelty on the fly, which was entirely missing from the legacy...
Build a Highly Autonomous Yet Unreliable Agent in Minutes
Sharing a fun recipe for building a highly autonomous, moderately capable, and very UNreliable agent using the open source aisuite package that Rohit Prasad and I have been working on. With a few lines of code, you can give a frontier...
Scale Revenue by Targeting the Right Customers First
I asked 100 successful sales leaders why startups fail to scale revenue. Their answer? It was not because the product is bad. They stall because they’re growing on the backs of the wrong customers. In this The Science of Scaling...
RunwayML's World Models Launch Holodeck‑Style Virtual Beings
OK, I think everyone is missing just how big a deal @runwayml's World Models, just announced, are, along with a raft of other new things, including new avatars that really are virtual beings that are very high quality. Hey @TrishaCode...
Transform with AI Agents, Not Just Automate Processes
Are you automating the insanity or transforming your business? Most leaders get AI agents wrong; they speed up old processes instead of reimagining them. Chris Hallenbeck from @Boomi shared how @serco transformed annual certification checks into continuous real-time monitoring. It resulted in...
AI‑driven Startups Will Hit $100M per Employee
Surge CEO Edwin Chen expects to see many $100M revenue/employee startups in the next couple of years "When we started Surge, we wanted to build it differently. With a super small, super elite team. What's crazy is that we actually...
Build a Playful Autonomous LLM Agent in Minutes
Sharing a fun recipe for building a highly autonomous, moderately capable, and very UNreliable agent using the open source aisuite package that Rohit Prasad and I have been working on. With a few lines of code, you can give a...
Discovering Hidden Replit Features After Extensive Use
I’ve been using Replit for 5 months and probably 300 hours in And just saw this feature … now Exposing features once you are feature-rich is a non-trivial task https://t.co/xkt2ZQNvbC
AI's Power Already Here; Change Unfolds Gradually
You can argue timelines, risks, or regulation. Existing AI capabilities are already sufficient to drive long-term change. What people miss is how disruption actually unfolds. It takes time for systems, incentives, and habits to reorganize around what already exists.
Never Miss a Brand Mention: Monitor Online Now
Five Reasons Why You Absolutely, Positively Need to do Online Brand Monitoring https://t.co/cpOBPyWl4W So you don't miss brand mentions like these pubs.🫤 https://t.co/pEPTwabw0t
AI Startups Racing Ahead; I’ll Miss Christmas Dinner
Gemini, OpenAI, Cursor… everyone’s cooking like crazy. Keep this pace and I’ll be at Xmas dinner like: https://t.co/z7YZV7vTlu
Delian AI Neutralizes Aerial Threats From Desert to Arctic
from the desert to the arctic, @delian_ai detects and takes down aerial threats
Streamlined Car Dealership Service with Fizzy Columns
Nice column setup for managing customer service at a car dealership using Fizzy.
A Decade with OpenAI: Unimaginably Special
It has been a very cool last 10 years; OpenAI has been more special to work on than I could have possibly imagined.
World Model War Unleashed: Enter the Holodeck
The war of the world models is on! AKA the Holodeck.
AI Can Outperform Human Account Executives—See Proof
Think AI can't beat a human AE? Try https://t.co/XobWWB7nQi You might be surprised https://t.co/e6UjVoZEgC
Remarkable Advances Beyond GPT‑5.1 in New Model
It is a very smart model, and we have come a long way since GPT-5.1: https://t.co/6FJG5FbOQG
World Model Unveiled as Key to General Simulation
At about 19 minutes into this they announce their world model. "The best way to achieve general purpose simulation." Really stunning stuff.
Actionable Strategies to Reduce Customer Churn
RT @VisionEdgeMktg 📉 Combat customer churn with actionable strategies and lower your churn rate. https://t.co/ukddWvztPO #Churn #CustomerSuccess #Growth