AI's First Real Test: Designing Drugs at Isomorphic Labs
Isomorphic Labs Is About to Find Out If AI Can Actually Design a Drug https://t.co/vhQTwhIO85
Watch New Metrics, Not EPS, for Next $5T Shift
4 of the 5 biggest companies on earth report next week Stop watching EPS..watch these instead: $GOOGL - Cloud growth rate. If revenue this quarter $AAPL - China revenue and Vision Pro disclosure or omission The guide and the segment splits are where...
AI‑Enabled Engineers Command Premium Pay in Tech
They are paying this much for standout software engineers - who can generate better software, faster, using Claude Code vs “just” avg sw engineers (who do OK with it.) AI amplifies existing ability, and the best in any indusrty (who learn...
AI Misreads Banana: A Glimpse Into Machine Cognition
🤔Today's curious journey into AI computation vs. human cognition 🍌The Banana That Wasn't https://t.co/4PSoJn6Yee #AI

Hybrid Graph-Vector Retrieval Drives 97.9% Recall@5
For GBrain I built a proper eval harness. 145 queries, Opus-generated corpus. The retrieval stack uses graph based, vector based and Grep based strategies in combination. The graph layer is worth +31 points on precision. Vector-only misses 170/261 correct answers...
Spike in Phishing DMs Suggests X Account Breach
getting so much phishing email in my X DMs. either a lot of accounts have been hacked or someone has discovered a back door to posting DMs.
AI Showdown: Claude Vs. GPT Battle for Supremacy
I told Claude Code / Opus 4.7 and Codex / GPT 5.5 they would both be competing to see who could implement the prompt better. Winner gets to keep implementing, loser will die.
AI Opinions Split: Not Everyone Predicts Job Extinction
CC @mattyglesias and @KelseyTuoc. Yes, some AI people think AI will take all the jobs and possibly destroy the human race. But many others don't!

Students Should Not Use AI as Ghostwriters
Don’t let your students use #AI as a ghostwriter by Yanjun Shen @Nature Learn more: https://t.co/KuTaHIKesW #MachineLearning #ArtificialIntelligence #ML https://t.co/wT8bm9c178

Terrible Headline; Trails Filing for Divorce Soon
This is actually a terrible headline, lacks many elements critical to SEO best practices and does nothing for pickup via social media or A.I. ingestion. Please alert the local superior court that the Trails will be seeking a divorce in...
Judges Should Use Social Media to Democratize Courts
I look forward to chatting with my fellow Georgian @katieleebarlow on “In the Courts” (@fox5dc) this evening about my latest article, “Democratizing the Judiciary: Why Judges Should Engage ‘We the People’ Through Social-Media Platforms.” https://t.co/KRVMRkJ6uI
Rejecting AI Outputs Is the New Essential Skill
Are you rejecting more AI outputs than you are accepting? How often do you get an output and say no, then get a new output and say no., and then get another output and say no? Rejection is the new AI skill?...
MIB‑626 NMN Shows Lifespan Boost and New Mechanism
1. No living forever 🙈 2. Some MIB-626 (crystaline polymorph, pure NMN) human clinical trial results are in 😀 3. About to resubmit a revised mouse MIB-626 paper with Alice Kane, showing improved health measures + lifespan & a putative new mechanism...
Spam Texts Masquerading as Friends Signal Platform's
Latest sign of the end of x: overwhelming number of spam private text messages supposedly from people I know, but in fact, pure spam/phishing
Most Viral Clips Powered by Chinese AI Tools
That Video on Your Phone Might Be Made-in-China AI—From short clips to Hollywood, creators lean on AI programs, many of them Chinese @raffaelehuang https://t.co/oAC8UaLZZn https://t.co/oAC8UaLZZn
NTLA Set to Unveil First In‑Vivo CRISPR Phase 3 Data
Here is a video of me entering my office tomorrow knowing that $NTLA is about to present the first-ever Phase 3 data of an In Vivo (!) CRISPR Gene Editing Program. Somehow - and after @adamfeuerstein’s🧵👇- I have a feeling...
1999’s CIH Virus First to Attack PC BIOS
#ThisDayInTechHistory. April 26, 1999. The first known virus to target the flash BIOS of a PC, the CIH/Chernobyl Virus triggers its payload on this day, erasing hard drives and disabling PCs primarily in Asia and Europe. https://t.co/urNvbAJTbh
Philippines Boosts 2025 Solar Capacity by 899 MW
Philippines adds 899 MW of solar in 2025 #energysky -- via pv magazine global: https://t.co/SulKnMlSYE
Do Bots Appear in Google Trends Data?
Hey @danielwaisberg - can you comment on whether agent/bot activity would show up in Google Trends?

AI Disruption Sparks Professional Boundary Battles
A thing I see missing from AI job debates is that as jobs are disrupted by AI, professions will compete over new boundaries Abbot's System of Professions is a good read on what happens historically. Here is a short cartoon summary...
HubSpot Extends Fetch Timeout to 120 Seconds for AI Apps
Current Status: Working on a major update to HubCode (The agentic coding tool for building HubSpot apps). The issue I (and other users) were running into was the 15 second timeout limit when using the fetch() function to call external...

Engage with Your Content or Lose Prospects
If you don't want to engage with your content, your prospects probably won't either @TBorreson11 https://t.co/goh06qr7OA #personalbranding #networking #community #digitaltransformation #digitalmarketing #digitalselling #socialselling #belonging #culture #customerexperience https://t.co/HcG8mAW2as
Earn Trust by Knowing Buyers' Problems Better Than They Do
If you can't describe your buyer's problem better than they can, you haven't earned the right to present a solution. I closed $3M in new ARR per year for two years running at Gong by living that rule on every single...
Robot Mirrors Human Motion with Near‑Zero Latency
Motion-Synced #Robot Mirrors Human Movements with Near-Zero Delay by @IntEngineering #Robotics #Engineering #Innovation #Technology https://t.co/ALRFvbvnDJ

IOS 26.3 Beta Adds New Live Weather Wallpapers
Apple keeps enhancing and expanding the live weather wallpaper and lock screen options in iOS 26. Here are some of the latest options in iOS 26.3 [release candidate beta] and how to try them... https://t.co/iwvpGcmjUL #iphone #ios26 #weather https://t.co/z6jW7As0Rj
SAP Rollout Costs Companies Millions; Risks Must Be Managed
SAP implementation led to a 16% sales decline, an $8% revenue drop, $25M inventory write-off, and a $330M revenue guidance reduction. Understanding the root causes and fallout is crucial for managing SAP project risks. #SAP #ProjectManagement #RiskManagement https://t.co/rJBHSGzEII

Moto Razr Pricing Pairs High‑end Chips with Low‑end Models
The 2026 Moto Razr lineup Razr Fold: $1899 Razr Ultra: $1499 Razr Plus: $1099 Razr: $799 Snapdragon 8 Gen 5 for $1899 and Snapdragon 8s Gen 3 for $1099 are some very odd choices
Autonomous Nomadic Drones Boost Grid Resilience
Nomadic #Drones Revolutionize Grid Resilience with #Autonomous, Self-Recharging Inspection Systems via @WevolverApp #EmergingTech #Innovation #Technology #Tech https://t.co/1WN35ORJtB
Twitter Still Calls It “Major Spam,” Ignoring Scaled Abuse
Interesting that they still send “major spam” and not “scaled content abuse” manual actions Goes to show you how they really feel about scaled content 😅
SpaceX’s 2025 Launch
How did SpaceX spend $3.6B of capex in its launch business in 2025 (compared to $4.1B of revenues and $3.5B of expenses)? How much of that was on Starship (it is reported that Starlink was a separate $4.2B capex line...
5 MW Battery Ready This Year Cuts Peak Costs
“A distribution-connected 5 MW battery can be deployed this year, at a fraction of the cost, and begin shaving coincident peak exposure immediately. “The number the transmission utility has to solve for, then, is lower,” https://t.co/hKXw8KnF7M

Waymo's Safety Hinges on Local Street Regulations
Waymo cannot make streets safer (or not). City and state policies make streets safer (or not). Waymo will act within whatever street-safety regime cities and states decide to adopt, for better or for worse. If SF penalized the company for...
Italy Issues 30 MW Floating Solar Tender
Italy launches tender for 30 MW of floating PV #energysky -- via pv magazine global: https://t.co/C9e5XA9jum
Dedicated AV Lanes Boost Traffic Flow and Cut Latency
Once self-driving cars are sufficiently deployed, we can create dedicated lanes for them with higher speed limits and closer following distances between cars. This will both improve throughput and reduce latency.

Samsung Hints at New Flagship Camera Design
Samsung is apparently planning a camera redesign for the next flagships Picture is of the Xperia 1 VIII

Unpredictable AI Shouldn't Be Treated as Ordinary Software
The Future of Life Institute released a video about my work and message. I did not know they were making it, which is charming, because most unannounced developments in AI safety begin with “we observed unexpected behavior” and end with...

Ultimate Claude Code Resource Compiled in One Thread
🚨 CLAUDE CODE BUILDERS 🚨 Bookmark this immediately. You'll thank me later. THIS is the ultimate resource bible for Claude Code, and I’ve curated all the links for you in this 🧵↓ https://t.co/sXwRVKBDPN
Free, Accessible Robotics Lessons for Real Understanding
Robotics education built for people who actually want to understand it… not just pass an exam. [📍FREE ] Peter Corke’s Robot Academy breaks down robotics into short, focused video lessons. What it focuses on: • Robot motion and coordinate frames...

User Calls for Unified Usage Dashboard Across All Claude Products
@bcherny @felixrieseberg I like the Claude Code dashboard in the app, but I wish there was a similar dashboard for my full account, showing me token and model use across Chat/Cowork/Claude Code. The current one has such a big blindspot...
China's Solar Exports Could Brighten Africa's Underused Sunlight
“Africa is the sunniest continent on the planet. But despite its abundance of natural light it generates less than five percent of its electricity from solar energy. China’s surging exports of solar panels could change that.” @economicsnoah https://t.co/iEIden3G7Z
Organization Design Drives Modern Strategic Workforce Planning
Organization Design in 2026: The Heart of Strategic Workforce Planning Today @visier https://t.co/W2AIe1WRMs #HCM #HRM #HumanResources #HRTech #CHRO #FutureofHR

Top 25 AI Tools Across Every Workflow Category
25 killer AI tools across the stack 🔥 🤖 Bots: ChatGPT, Claude, Bard/Gemini, Bing AI 🎬 Video: Runway, HeyGen, Veed, Pictory 🎨 Images: Midjourney, DALL-E 3, Leonardo, Firefly 📊 Slides: Tome, https://t.co/6DMRN1K0uS, Decktopus, https://t.co/16XgbWqxwl ⚙️ Productivity: Taskade, Notion AI, Xembly ✍️ Writing: https://t.co/CU0yRbEKbN, Grammarly, Jasper, Wordtune 🔎...
True Topical Maps Show Page Linking, Not Keyword Lists
Most "topical maps" are just keyword lists in a spreadsheet. A real one tells you which page links to which, in what order, with what anchor. If yours doesn't show the wiring, you aren't there yet.
General-Purpose Humanoid Robot Uses Single Brain for Multiple Tasks
"One Brain for Diverse Uses" General-Purpose Humanoid #Robot via @ZappyZappy7 #Robotics #Tech #Engineering #Innovation #RPA https://t.co/gbVN5sFf9z
Rate Limiting Essential to Curb Runaway API Costs
i have the minimax ultra plan that gives me 30,000 api calls/5 hours. i had to build a rate limiter to keep it from maxing out and getting other 429 rate limits. several times claude code unfortunately added opus as...
Why We Overcomplicate Simple Tasks with Prompt Chains
The preference for writing 10 sequential prompts to fix something that would take 10 seconds to do by hand must be studied
Banking Is Now Fully Scriptable via Command Line
All banks are now in the command line Think about that for a second Your grandmother's checking account Your mortgage Your savings All accessible via terminal commands We went from marble lobbies to APIs in one generation The friction is gone The gatekeepers are code The future is scriptable Finance...
Mapping Global Semiconductor Process Nodes in One Guide
#Technology #Newsletter #Semiconductor #Manufacturing #Node NLOG-301 | Semiconductor And Beyond Newsletter | The Semiconductor Node Map: https://newsletter.chetanpatil.in/p/semiconductor-and-beyond-newsletter-301

Deploy AI, Not Just Pilot, to Transform Banking
Pilot programs don’t create value. Deployment does. The banks that operationalize AI will turn investment into impact while others fall behind. Download your free copy of Agentic AI: Powering the Self-Driving Bank: https://t.co/BkPDkgVWre https://t.co/JvZFvOF49a
True E‑commerce Flex: Automated Freedom, Not Luxury Cars
The ultimate ecom flex isn't a Lambo. It's a month-long vacation where you don't check your phone once because your systems are running the business for you. Build for freedom, not for flexing.