Duchenne Kids Show Dramatic Improvement After Microdystrophin Treatment
A couple of weeks ago when I visited Solid Bio, they showed me some videos of Duchenne kids pre and post microdystrophin treatment that I was amazed by - but they weren't sharable yet. Bo just presented them at Needham this week. So cool. https://t.co/VB7ag7ole9
Uber Overspends AI Budget; Early Hype Soon Wanes
Uber has already exceeded its annual budget for AI tools due to internal usage of tools like Claude Code. We’re in a honeymoon period when it comes to AI agents which will end as companies figure out where it adds value...

Two ePA Routes for Same Drug Create Workflow Chaos
A rheumatologist prescribes Humira for a patient with Crohn's. The patient might self-inject at home with a prefilled pen or come into the infusion center for IV administration. Same drug, doctor and patient, so must be straightforward, right? Under CMS-0062, two...
Scammers Clone Slack Downloads to Distribute Silent Malware
Scammers are cloning Slack download pages almost perfectly. Same layout, same buttons, and the same Download experience. You have to install. But instead of Slack, you end up with malware running quietly in the background.
Institutions Bet Early on Digital Finance Infrastructure
The real money comes from institutional investment, and it's flowing into the infrastructure will supports the whole financial system. The smart bets are being placed on the utility layer, the backbone of digital finance. The biggest moves happen long before...
Kalshi Launches Commodity Markets, Deepening Finance Foothold
while all the legal fights continue, kalshi is really doing everything it can to entrench itself in the financial industry

Multi-Omics Integration: Complex Realities Beyond the Hype
Thread: Multi-omics sounds cool—until you actually try it. Here's are the nuances. 1/ You’ve got RNA-seq. Methylation. Proteomics. Time to “integrate” the data. But how? And why? Let’s break it down. https://t.co/Wxhcp6OJ68
Mythos Built on Modest, Globally Accessible Compute Resources
Great rejoinder to some of the worst analysis of the implications of Mythos from the predictable quarters... "First of all, Mythos was trained on fairly mundane capacity and a fairly mundane amount of it by an extraordinary company. The amount of...
AI Voice Tech Finally Sounds Natural, Not Robotic
This is a big shift for AI voice tech. Customer service calls, personal assistants, voice agents, audiobooks, and apps are all about to feel way more natural and less robotic. The age of “sounds okay on a demo but weird in real...

Comments Dominate; LinkedIn Profiles Poised for Growth
I'm writing a newsletter recap from Social Media Week — but first some bullet point thoughts: - Comments are and will be everything - LinkedIn has tons of growth potential (for personal profiles according to Metricool) - Molly McPherson is the GOAT -...

Proof Comes in Tiers: Rank Yours Strategically
Not all proof is created equal. How does yours rank up? So if you’ve been following me for a while or done any of my programs, then you already know that I talk about proof… A LOT. You can have the best product...

Edge Computing Slashes Latency, Boosts Safety and Bandwidth Efficiency
Edge computing cuts latency by processing data near its source, at the device. Services in factories and mobility push teams to deploy local intelligence, since milliseconds affect safety and uptime, and local processing trims bandwidth spend. Microblog by @antgrasso https://t.co/rCMiEIRtCQ
Delay Outsourcing Fulfillment; Leaders End up Packing Boxes
60% of online retailers already outsource at least part of their fulfilment. The ones who wait too long? They're the ones spending leadership time packing boxes instead of growing the business. Know the signs 👇 https://t.co/r4ctl4lH4h

Learn SQL Through Games, Not Dry Tutorials
You can learn SQL by playing a game. I am not joking. Most people quit SQL tutorials because dry exercises on fake datasets feel pointless. These free games give you a reason to write queries. A murder to solve. An island to...
Holistic Media Mix Beats Legacy Tactics in Furniture Marketing
In Episode 3 of From Screen to Store, sponsored by @JamLoop , Alex Back, CEO and Co-founder of Couch, joins hosts Jeremy Bloom and AdTechGod to discuss what’s actually working in modern marketing and why legacy industries are falling behind. The...
Predicting Human Behavior Lets Us Shape the Future
Another excellent feature from @mjnblack on Aaru, a startup founded by three teenagers that uses AI for predictive analytics. This line gave me chills: “To predict human behavior is to predict the future,” Fink argued. And “if you can...
AI Trends 2026: Transforming Teaching Beyond the Classroom
🎧 A new bonus episode explores emerging AI trends for 2026. 📊 @WillcottJulie and I discuss how AI is shaping teaching and learning beyond the classroom. 🤝 I’m excited to partner with @jotform to share insights educators can apply right away. ...

Anti‑amyloid Drugs Show Trivial, Non‑meaningful Cognitive Benefit
The effect of current anti-amyloid drugs vs Alzheimer's disease is "trivial" for cognitive function or dementia severity, not clinically meaningful, from a systematic @cochranecollab review of 17 trials, >20,000 patients https://t.co/9A6PeZOyAt https://t.co/c1PCOYZxws
Rapid AI Iteration: Essential for Every Modern Business
We just did a 90 minute hackathon as a team. We hired an ai consultant to build us a sourcing tool better than all the tools we previously used. We then spent 90 minutes all on a zoom using it,...

Anthropic Shuts Claude Max, Developers Migrate to Alternatives
Anthropic just pulled the plug on Claude Max for autonomous agents. If you were running 24/7 coding workflows on your $200/month plan, they stopped working four days ago. The devs who saw this coming already moved. Here's where they moved to: https://t.co/jVH3O0xvqJ
Midwest Boutique Says DRAM Price Forecasts Stabilizing
Did Midwest Boutique send a cautionary commentary out on $MU ? "Our work suggests conventional DRAM price forecasts are stabilizing somewhat after continued meaningful upside"

Cut SEO Update Work by 90% with AI Tool
I have 20+ content assets that need to be updated before a "re-rank" event. I call these updates "Rank Enhancement". The whole idea is to take whatever pages you have and improve them based on the data Google uses to rank them. The...
Avoid Offerwall: It Will Frustrate Your Users
Offerwall, or as I call it, "Navboost Killer" is now generally available to all publishers. I highly recommend NOT implementing Offerwall. You will anger and frustrate your users to no end. I have covered this before. Beware.

AI Drives Structural Transformation in Transportation
🚀 Artificial Intelligence is reshaping the future of transportation — from predictive maintenance and smart mobility, to logistics, infrastructure, and customer experience. In my latest article, I explore how AI is becoming a strategic lever for CEOs and entrepreneurs, helping organizations...
AI Breakthroughs in Language, Vision, Browsing Arrived Together
If you had told an AI researcher in 2016 that in 6 or 7 years, computers would be easily able to communicate in language?Would it have been obvious to them that other non-obviously linguistic capabilities (image generation, web browsing, etc)...

MGTX Buys Back XLRP Gene Therapy for $25 M
$MGTX just announced that it has entered into an asset purchase agreement with $JNJ to acquire back its bota-vec Gene Therapy program for the treatment of X-linked retinitis pigmentosa (XLRP) 🧵👇 for an upfront cash payment of $25M & a...

Pixel May Finally Support Per‑SIM Custom Ringtones
Your Google Pixel may finally start letting you set custom ringtones for each SIM card Some phone manufacturers already offer this feature for dual SIM users for a long time ✅ Details - https://t.co/q4spmZccsH https://t.co/dhnsjusRNj
AI Paranoia Exposes Publishing’s Quantity‑Over‑Quality Culture
I wrote about how AI in book publishing is a labor issue. "AI paranoia is a symptom of a larger problem: a corporate culture that values quantity over quality, quick output over the very human labor of poring over a...

Midday Fast Charging Leverages Low Solar Prices, Reducing Cost Exposure
Fastned: "Fast charging peaks at midday, exactly when solar generation pushes electricity prices to their lowest. ⚡️throughput naturally avoids the costly morning & evening peaks, creating a structural hedge: more MWh delivered doesn't mean proportionally higher cost exposure." https://t.co/HO96yJFNhp
Telegram‑sold Tools Let Scammers Breach Bank Security
Cyberscammers are bypassing banks’ security with illicit tools sold on Telegram | MIT Technology Review https://t.co/6F7Bho2ZXd
FDA Approves Kidney Drug Despite No Functional Benefit
This week's Biotech Scorecard newsletter: $TVTX Travere Therapeutics' drug for a rare kidney disease doesn’t improve kidney function. The FDA approved it anyway. https://t.co/63hDsPfOcT
Google Testing Real-Time Voice Live Mode on Gemini Desktop
Live Mode on Gemini desktop -> Google tests Live Mode with screen sharing for Gemini desktop "Hidden within the app's settings are configuration options for Gemini Live voice mode, including the ability to select from different voices, mirroring the...

Digital Tech Will Revolutionize Healthcare: 20 Future Trends
Digital technology could help transform unsustainable healthcare systems, provide cheaper, faster, and more effective solutions for diseases – and could lead to healthier individuals living in healthier communities. In this book, we analyze the top 20 trends shaping the future of...

Instagram Adds In‑Reel Affiliate Tags, Boosting Creator Earnings
ICYMI: Instagram is rolling out the ability to use affiliate links to tag products in Reels. 🛍️ This removes friction that often comes with creators driving audiences to their link in bio or using comment automations to share affiliate links, likely...

GLP‑1 Drugs Don’t Disproportionately Reduce Functional Muscle, DXA Misleads
1/2) New research suggests GLP-1 weight loss drugs probably do NOT cause disproportionate loss of functional lean muscle. The confusion has arisen from the fact that DXA scans capture and pool a lot of different organs and tissues into the category...

Google Ads PMax Spend Trends Across Channels
Google Ads PMax channel performance report on the insights report that shows spend over time per channel https://t.co/1qbNeb12Tq via @AndrewLolk https://t.co/FE8snV6sFF
Join Our Autonomous Labs Q&A Session Today
Excited to share details on our Autonomous Labs and do Q&A today for @SLAS_Org ! Can register at link below 👇

Progress MS-32 Adjusts ISS Orbit for Soyuz Missions
Progress MS-32 conducts ISS orbit correction in preparation for Soyuz MS-28 landing and Soyuz MS-29 launch. DETAILS: https://t.co/pRxO5i4W6h https://t.co/67eNSveV1q
AI Shifts to Supply Shortage, Security Holdbacks, Utility Regulation
New newsletter: AI’S TRIPLE VIBE SHIFT We’re passing into a new era of AI, thanks to several phase changes 1. From fears of a demand shortage (ie, a bubble) to the reality of a supply shortage (ie, not enough compute for...

FinTech Fund Helps CarryHQ Secure AngelList Sale
Big congrats to @ankurnagpal and the team at @carryhq_ on the sale to @AngelList. Glad that we could support you from @thefintechfund 🙌 https://t.co/ToMKqLpS99
Local LLMs Empower Diverse Cultures Beyond Big Tech
One corollary of the current local LLM drive is that it puts the power to train and finetune new models into the hands of people outside big tech giants. The result? More representation of global majority cultures and language. My...

McKinsey Reveals Blueprint for Effective Agentic AI
🚨McKinsey just dropped how to build agentic AI (that works) Here's everything you need to know in 2 minutes:
Turn PAA Questions Into Subheadings for SEO Wins
Most bloggers ignore this goldmine: “People Also Ask” (PAA) Every question in the PAA box is a ranking opportunity. Take those questions, turn them into subheadings, and answer them directly. Now your post is optimized for: • Featured snippets • More SERP real estate • Higher authority...
Roche Initiates New Elevidys Trial Targeting EU Approval
Roche to launch another Elevidys trial, with eyes on European approval https://t.co/eAANNiihpt via @DrewQJoseph $SRPT
AI Micro‑Drones Replicate Insect Flight and Smarts
#AI-Powered Micro #Drones Mimic Insect Flight and Intelligence by @pascal_bornet #Innovation #EmergingTech #TechForGood #Technology https://t.co/qVeqLsvs4O

Soyuz‑5 Launch Window Closes Amid Swirling Rumors
The inaugural launch of the new Soyuz-5 launch vehicle approaches the end of its available window without any official news, so I tried to untangle a morass of rumors and hints about the zig-zag path to flight for our subscribers:...
If You Worry About Windows Privilege Escalation, Your Security Fails
Repeat after me: Your security program is not good enough to have to worry about escalation of privilege on Windows
Sun‑Tracking Solar Panels Boost Yield, Yet Add Cost
Solar panels that automatically track the sun sound like a clear upgrade. More exposure. Higher efficiency. Better output throughout the day. And in many cases, that’s true. Tracking systems can significantly increase energy yield compared to fixed installations, especially in regions with strong, consistent sunlight. But...

Claude Code Routines Replaces Drag‑Drop Automation for Everyone
i think anthropic just killed n8n they launched Claude Code Routines and it's a direct 1:1 replacement for drag-and-drop automation builders here's why this is a big deal for non-technical people: the hard part of automation was always the middle layer. the logic....
AI Design Tool Replaces Figma for Fast, Affordable Wireframes
I cancelled my Figma subscription a few months ago, and I haven't missed it once. I've been using an AI design tool instead ([https://t.co/W5sOEuK90l](https://t.co/W5sOEuK90l), if you're curious), and the workflow is genuinely different. You paste in your content, it generates complete...