
AI-Driven Precision Oncology Breakthrough From Korean Researchers
One unexpected but very insightful paper in Nature BJC from a leading institution in Korea on precision oncology and AI-driven drug discovery. I read it with great pleasure and you should read it too. https://t.co/vpxofjt9Mn https://t.co/SXs4n72CcY
Create AI Solutions, Not Just Consume Them
Most people consume AI content. Few people actually create with it. That’s the gap. If you can build systems that: * save time * increase revenue * improve experience You’ll always be valuable.
Innovation Thrives in Quiet, Hands‑On Exploration
A typical Wednesday evening. Silence at home. And then: tech. 💡 Siemens TIA Portal open, the Siemens ET200MP in action testing a special output module with pulse width modulation driving an LED strip 🔧 And of course… some chocolate for...
China Trials Deep-Sea Submarine Cable Cutter at 3,500 M
China tests submarine cable cutter at 3,500-metre depth Maybe "salvage" and "maintenance" vice "cutter", the cutting is not the primarily capability.... https://t.co/i2Wo4yNkyq
Dishan Technology Near 2nm AI Chip, 40% More Efficient
China’s Dishan Technology nears 2nm AI chip breakthrough, reports say Shanghai-based start-up says its chip design is likely to improve energy efficiency by 40 per cent compared with its predecessor Technology finds a way around controls, eventually... https://t.co/gaSkdYcIks

Cadence Sets Ambitious 2026 IP Bandwidth Targets
IP targets for @Cadence in 2026. 😎 ➡️ HBM4/4E 16G ➡️ LP6 at 14.4G ➡️ PCIe 8.0 and 448G ➡️ Intel 18AP and 14AE #CadenceLive https://t.co/DYAF0yQT2Z

Speculating Apple’s Next Device: IPod Photo or Touch
@gruber iPod Photo? iPod touch? (I don’t think it’ll be called iPhone Fold either, fwiw)
General Atomics Plans Drone Ops From Rugged Mojave Fields
Hunting Drones From Sloppy Airstrips Is General Atomics’ Future Vision For Mojave Pushed forward to very rough fields, Mojave could also escort helicopters, strike targets, provide surveillance and networking, and even transport cargo. https://t.co/NlEFJn5GHa
All‑In‑One Creator Suite for $2499/Year
I'm working on a project to bring Jordan Crawford in your Claude Code terminal... but it will be a WHOPPING $2499/yr... but... Here's what you will get: 1. All of my work synced weekly or daily (abstracted from clients) in...

AI‑Powered Dashboards Turn Finance From Maintenance to Decision‑Making
AI dashboards > spreadsheets 📊🤖 Describe the question AI builds the dashboard You tweak logic & visuals Insights arrive in the meeting Finance shifts from maintenance → decisions. #AI #FPandA #Dashboards #GenAI #Analytics https://t.co/iiASiEm8I8
Cadence Tools Can Be Accelerated on Snapdragon CPU/GPU
Pretty sure I just heard Anirudh claim you can accelerate Cadence tools on Qualcomm Snapdragon CPU and GPU. 😉

Get Ready for AI Shopping and SEO Evolution
How to Prepare for AI Shopping & the Future of E-commerce SEO with Tim Resnik Post: https://t.co/yXnT36Bq2w https://t.co/UjNxYRqOrx
Enterprise Software Deals Now Driven by Rapid Customer Flux
"The deal" in enterprise software is fundamentally changing. One side of "the deal" has been written about a lot - the vendor side: * Recurring revenue => constantly re-evaluated * Finite direct competitors => everyone is a competetor * Gradually easier over time =>...

From Zero to 10K Followers in 3 Months
I grew the 𝕏 account of @vitaliidodonov from 0 to 10K followers in just 3 months. Lots of people have asked me how I did it. So I just wrote up an entire PDF explaining my strategy. If you want the full case...
Mac‑First AI Strategy Calls for Standalone Gemini
Mac users are a high-signal audience for AI tools, so a dedicated @GeminiApp here makes sense. @AnthropicAI has been running a Mac-first playbook for the same reason. Early adopters skew Apple, and that's where the feedback loops that actually shape...
Claude Downtime Forces Users to Switch to Grok
So, @AnthropicAI how am I supposed to use @claudeai when the service is unavailable? Right in the midst of a critical project all of my work is lost. Having greater capabilities is useless if the service is down. I pay...
AI Unifies B2B Site Pages Into Cohesive System
Most B2B websites die the same way. Someone ships a strong homepage, everyone celebrates, then every new page becomes a fresh writing project. The result is drift, repetition, and a site that does not feel like one thing. In the next live...

Elon Bets, GLP‑1 Relevance, and Consumer Sentiment Slump
🆓 Wednesday links: betting on Elon, why GLP-1 pills matter, and what's driving poor consumer sentiment. https://t.co/wCKQe3osVm image: https://t.co/QkWrhkJpqj https://t.co/aCwEbtyhzI

Prepare Your Store for AI-Driven Shopping and SEO
New: How to Prepare for AI Shopping & the Future of E-commerce SEO Google, OpenAI, Amazon, and seemingly every platform are introducing new protocols + data feed attributes for folks who sell things online But what should folks in e-commerce do now?...
Soon We'll Nostalgically Recall This LLM Golden Era
Believe it or not -- I sense we are going to look back at this time as the "good old days" of LLMs (before they became either impossibly expensive, driven by advertising interests or other enshitiffication)
Run OpenClaw in the Cloud, Not on Your Laptop
OpenClaw is the best AI agent I've ever used. I run it every single day. But if you asked me to run it on my laptop full-time, I'd say you're making a mistake. OpenClaw is brilliant for accessing your files, reading your apps,...
Nokia, Orange Team up for AI‑RAN, 6G‑ready Platform
Nokia and Orange to work together on AI‑RAN including: -GPU-based radio processor -NVIDIA AI infrastructure -the upper 6 GHz band -6G-ready platform https://t.co/ELP6q2vGh8
Google Gemini Tests Built-In Shopping Cart for Seamless Checkout
Expanding agentic shopping soon? -> Google Gemini is testing a built-in Shopping Cart and revamped settings "A dedicated cart inside Gemini would give that checkout flow a persistent home, making multi-item purchases and comparison shopping more practical for everyday users."...
Allbirds Shifts to AI, Secures $50M Financing
Allbirds pivots to an AI company and raises $50M via convertible financing. Nothing surprises me anymore.
Starlink Drives 75%‑80% of SpaceX’s $1.75T Value
Here's what most people miss about SpaceX: 75–80% of its value isn't rockets. It's Starlink. The satellite internet business that nobody believed in is now the backbone of a $1.75 trillion company.
When Sneakers Turn Into AI GPU Service Providers
You know the world has gone cray cray when a shoe company is pivoting to an AI GPU as a service business. https://t.co/3fy14Wd8WE
Emotional Regulation Beats Marketing in E‑commerce Success
The most underrated ecom skill isn't marketing. It's emotional regulation. Staying calm when your best ad account gets banned. Not getting euphoric over one good sales day. That's the real game.
Solo Founders Need One Unified AI, Not 13 Agents
Most solo founders don’t need “13 AI agents.” They need one system that remembers the whole business and doesn’t hallucinate. AI feels useless when it lives in 5 different tabs, forgets every conversation, and can’t see your revenue or launches. The OS shift:...
Finance Teams Embrace Agentic AI, Yielding 3.5× ROI
44% of finance teams will use agentic ai in 2026. that is a 600%+ increase from the prior year, per wolters kluwer. gartner forecasts 40% of enterprise apps will embed ai agents by 2026. up from less than 5% in 2025. per...
CEOs Co‑author Quantum Verification Paper, Celebrate AQT Partnership
Delighted to be working with AQT. Fun fact: Horizon Quantum and AQT CEOs (along with many others) co-authored a paper back in 2021 using quantum computers to check each others work: https://t.co/GUKksFtBkV
Practitioner Input Needed: AI Can't Perfect Cloning Tools
Cloning tools suck so much I decided to make my own, lol. Low hanging fruit yes, but without input from people who actually regularly do molecular cloning its the same like any other tool not made by practitioners of said...
LLMs Reduce Geo Cannibalization: Favor Many Long‑Tail Pages?
Has anyone in SEO been able to validate (or disprove) the theory that content cannibalization matters LESS for GEO given that LLMs are prioritizing long-long tail pages? In other words, are there any credible studies that have shown it's better to...

Industry Highlights $6.5B Solar Waste Opportunity Amid Politics
“This is a $6.5 billion opportunity:” Industry claps back at toxic political fear-mongering on solar waste #energysky -- via Renew Economy: https://t.co/ROFCOP4mYU https://t.co/gzxLpbgXHX
Meta Events Manager Faces Random Purchase Outages, Performance Plummets
We are seeing purchase outages left and right on Meta events manager with some of the worst performance in the last 3 days. There doesn't seem to be any rhyme or reason here.
Human Safeguards Lower Risk, but Can't Fully Prevent It
However, Yampolskiy pointed out, “human safeguards can reduce risk, but they do not eliminate it.”
Nuvacore AI Emerges, Targeting AI‑optimized Datacenter CPUs
Congrats to @NUVACOREAI coming out of stealth and the @sequoia investment. The value prop makes sense. Agents are driving the need for more and better datacenter CPUs, particularly in the hyperscalers. The company says it wants to overcome the limitations of...

2TB Archive Drive Costs $90 More Over Time
Here’s a 2TB drive I’ve been filling up with my archived photo and video projects over the past couple of years. I bought it for $220 and now it goes for $310.
Accelerating AI in the Workforce Through Real‑World Stories
Thanks Ashley Goldsmith and Christy Pambianchi for sharing these amazing stories of testing, learning, building, and accelerating AI in the workforce.
AI Outpaces Teams in Bug Detection; Adapt Response
AI discovers bugs faster than teams can respond https://t.co/2YNTbiuIjn < call me crazy, but I don't think the solution will be "stop finding bugs." We need to change how we respond to the valid influx.
Effective Prompts Turn AI From Trash to Useful Content
I've tried ChatGPT, Claude, and Gemini for complex writing tasks, and here's my verdict All LLMs are trash if you're not a good writer BUT, you can teach them to generate content that is 70% there, rather than word salad filled...
Testing AI Media Buyer Before Full Autonomy at 99% Accuracy
We’re about to start testing an AI media buyer. Essentially how it’s going to work is the AI buyer will come up with optimization ideas based on correlation between in platform, our MTA and MMM. Each optimization will be manually approved by...
Celebrating AI Job Cuts Is Socially Tone‑deaf
Being *excited* about AI eliminating the need for humans is anti-social behavior. ANTI. SOCIAL. BEHAVIOR. Don't get me wrong: If AI makes your company more profitable because you don't need to hire as many people, that's wonderful. As a rational business actor, I'm here...
Core Go‑to‑Market Principles Endure Amid Growing Complexity
🎧 I had a great conversation with Julian Castelli on the Growth Elevated Leadership Podcast. We dug into how go-to-market is evolving, from predictable revenue playbooks to the realities of today’s more complex, less linear growth environment. A lot is...
AI's Cycle: Hype, Minor Wins, Questionable Breakthroughs
This is becoming a pattern in AI that makes talking about capabilities challenging. First, there are overstated claims (like the flubbed Erdos problems last year), then minor wins (AI helps with discovery) then breakthroughs. The first stage feels like (&...
United's Starlink Shift Leaves Flights Wi‑Fi Dead
A bunch of anecdotes making me think that as @united moves the fleet over to Starlink their ground station partner has cut them off. I know of 5 people on 5 EWR-SFO flights who haven't had wifi in the last...

Essential AI Toolkit for Every Modern Professional
20+ AI tools every working professional should know 🧠⚡ From writing and research to meetings, design, and automation this is the stack. Which ones do you already use? Any I missed? 👇🏾
AI Trust Grows with Constructive Feedback, Not Flattery
Want to know what would make me trust AI more? I share my next big idea with it and it responds: "LMFAO. What a dumb idea. Next." Instead I get: "Chris you're so pretty and everything you say is correct."
MSL Pledges AI Safety with New Preparedness Reports
As we develop more capable models at the frontier, MSL is committed to safety and preparedness for AI. To demonstrate this commitment, we will be publishing preparedness reports for our models, in line with our new Advanced AI Scaling Framework. See our...

Canva Teases Game‑Changing Create Feature Launch Tomorrow
Zach Kitschke CMO Canva with Cliff Obrecht, and Cameron Adams co-founders kicking off with a preview of Canva Create's announcements tomorrow. Very interesting to see the disruption here. (Can't say anything till tomorrow) https://t.co/eLdvW8xiUm
Generic Patch Urgings Trigger My Context‑blind Security Advice
This is my "psychoanalysis by X" thread, yes, another one. Why am I so triggered by advice "patch this immediately" given with no awareness of my business/mission? (1/5)