The 2026 SaaS market will be like the market for selling water. But what’s the difference between Dasani, Evian, and the tap in your kitchen? Brand. Nothing else. “Having a product” is no longer the most challenging part of selling software. Everything is horribly, relentlessly commoditized. Anyone can spin up whatever they want to sell in a second. So what do you do? Some combination of channel, awareness, and brand. What story are you telling? What channels are you getting into? For me, it’s LinkedIn. For someone else, maybe it’s getting into Clay ecosystems. It’s different for everybody. People are trying to sell me sh*tty copies of LinkedIn and email outreach apps. And it’s like, why would I buy from you when I can build exactly what I want in a week? That in itself is kind of depressing, but that’s how it’s going to be.
Robot companies gas up. This shows that the rich people see a big new market coming. Yesterday at JPMorgan event happening in San Francisco, lots of VCs said they are making robots a bigger part of their business. Bets are being...
In 15 minutes, Michael King is joining SparkToro Office Hours to present what to do *DIFFERENTLY* to appear in AI tools vs. classic Google results. You should probably be there. I threw in a few samples from his deck as...
$NVO CEO Mike Doustdar was our guest on this week's live taping of the Readout LOUD. And yes, he spoke fairly plainly about his ambition to acquire another developer of obesity drugs. $5B - $20B doesn't matter, it's more about...

This isn’t a “learn AI agents” roadmap. It’s a permission ladder for autonomy. Skills → memory → coordination → control → monetization. Skip steps and you don’t get scale — you get outages. https://t.co/VIRjpY0gmx
Startup people reach for the word “pivot” when they want a decision to sound intentional. I’ve seen teams use it for everything from a careful course correction to quietly walking away from a plan that stopped holding up. Same word....

One model calling 10 APIs is NOT a multi-agent system.❌ This is one of the most common mistakes I see. Tools are capabilities. Agents are decision-makers. If one model decides what to do next and calls multiple tools, you still have one agent, not many. Misunderstanding this...

The future of personalization is permission based. AI must serve customer needs, not cross trust boundaries. https://t.co/dpD6MT21TW
What if the most dangerous moment in innovation isn’t failure…but the moment we decide the failure cost is “acceptable”? Here's the funny thing - that's just Wednesday. We do this for every innovation. This video kicks off a new chapter...

By 2026, #AI Could #Automate Up to 70% of Everyday Work Tasks by @Khulood_Almani #ArtificialIntelligence #MachineLearning #ML https://t.co/3ogpp8txYd
You would never hire someone full-time who hasn’t done the job. So stop giving consultants and talking heads who’ve never done the work the spotlight or your $$$$$. Experience matters. If you’re going to bring someone in, vet them like...
Stop waiting for your startup’s product to be perfect because it never will be and that's okay so launch, get feedback, improve.

New mouse study shows cortisol, inflammation, and low SIRT1 activity all lead to depression caused by reduced neuronal cholesterol. Could statins exacerbate? And since SIRT1 is NAD⁺-dependent, could NAD⁺ boosting help treat depression?
Synchronized robots, tested in 3D, to boost uptime and cut integration errors: This setup uses RobotStudio to simulate dual-robot coordination with precise axis timing and collision checks. Every move is validated in a digital twin before going live. - Full...
Global payouts are becoming default stablecoins Especially for cross-border. Here's a practical guide to evaluating when and how to use stablecoins for this use case
The 8 Biggest AI Agent Trends for 2026 That Everyone Must Be Ready For AI agents are evolving fast — these 8 trends show how agent based AI will grow and influence business, work and everyday life by 2026. Read...
A dozen years old, but curious how many of these little lies are still told around the #JPM26 conference.... "Top 10 Little White Lies Told At The JP Morgan Healthcare Conference" https://t.co/0er4Beffn3
Seeing Is Counting: Object Counting Powered by Computer Vision by @Ultralytics #Innovation #EmergingTech #TechForGood https://t.co/ZsIsqh5MrO

AI for memory shaped cities: when long horizon AI starts designing urban life. Our cities soon will be planned out using AI. @IrenaCronin and I write this newsletter every week. Long horizon AI uses historical data and simulated futures to guide...
Superhuman to Integrate Saifr's AI Agents to Support Scalable Compliant Enterprise Communication in Financial Services Perfect pairing: Superhuman's email productivity meets Saifr's compliance-native AI (Fidelity Labs origin). Financial services firms need AI that doesn't just write emails - needs to understand...

Thrilled to share that our latest work on injectable #magnetoelectric #antenna is highlighted by IEEE APS as one of the 25 𝐦𝐨𝐬𝐭 𝐩𝐨𝐩𝐮𝐥𝐚𝐫 𝐚𝐫𝐭𝐢𝐜𝐥𝐞𝐬 published in 2025 , reflecting the advances and ideas that shaped the past year.
If your AI feature, your AI product, your AI team, your AI copilot didn’t materially boost revenue … 👎 It doesn’t count Try again
#Robots Take Over Solar Panel Installation for Faster, Safer Deployment by @lukas_m_ziegler #Robotics #ArtificialIntelligence #MI #ML #Tech #Innovation https://t.co/dVZ12660S3

How has AI impacted science? Analysis of >41m papers. A paradox: Expansion of individual's impact but contraction in breadth of topics researched collectively https://t.co/npovh0eSL8 https://t.co/iMY3cEd9LE https://t.co/iErtpnuJQR
Most product work feels busy because it hasn’t touched reality yet. Real feedback compresses time. Internal activity stretches it. The longer you delay contact with users, the more convincing the fake progress becomes.

Why do so many apparently healthy people die or get severely ill from infections that would be considered low risk? For one, we don't have any way of assessing a person's immune system function in the clinic https://t.co/CshtAxDep9 https://t.co/uk5nDnyjnr

Continuous glucose monitoring sensor data, with a foundation model, predicts risk of Type 2 diabetes and cardiovascular outcomes better than HbA1c New @Nature @segal_eran @WeizmannScience @GLutsker "66% of incident diabetes cases and 69% of cardiovascular deaths occurred in the top risk...
There are no leaders on my team." That's not an observation. It's a confession. What you're really saying is one of two things: 1. I'm not creating the conditions for leadership to emerge 2. I don't have a method for...
Dismantling US vaccination policy will lead to more vaccine-preventable disease in kids. But how easy will it be to monitor the impact of the erosion of vaccine coverage? New data collection rule changes raise serious concerns about how visible results...

Space could be a testing ground for age reversal elonmusk. In 4 astronauts, epigenetic age of blood cells rose ~2 yrs by day 7 of orbit & returned to normal (or even younger) upon return 🚀 🌎 mason_lab @davefurman onlinelibrary.wiley.com/doi/10.1111/acel.70360
The AI insight problem that nobody's talking about 😳 We added AI to our customer research process. Suddenly, everything is labeled an "insight" 🤯 🫣 🫠 Customer mentioned pricing twice? Insight. Someone used the word "integration" in feedback? Insight. Pattern...
I’ve gotten a lot of messages asking about my BioPick selection for this year, $TENX. I’ve responded to a few but don’t have the time to respond to everyone. I actually considered making $TENX an official “pitch”, but I don’t...
Seven reasons why your AISDR pilot may have failed: 1️⃣ The playbooks and workflows were never developed and tested to begin with Technology is only as good as the strategy and processes built to enable it. Your AISDR tool isn't...
It’s officially event season again. And guess what? Conferences, RKOs, tradeshows... they are super hard. The planning, the logistics, the on-site craziness... the swag... 💙 Great experiences are super hard to produce and reproduce and reproduce I get asked fairly...
What's the connection between B2B influence, research and thought leadership? 74% of B2B marketers who frequently collaborate with influencers say their research-based content is very effective, versus only 29% of everyone else. That's a finding from our newest research report,...
Could you tell when an AI is nudging you to buy? That’s the next big trust test. https://t.co/hWNXoDpJXO @ConversationUS
"The UI is dead. Everything will be chat." This is the most dangerous myth in AI right now. I was talking about this with Lucas Puente , Slack 's VP of Research – and what we landed on changes how...
Wait, is he... endorsing sanctions evasion? Coinbase, per Pitchbook data, led Venezuelan crypto app @kontigo_app's funding round announced last Dec.
I nearly barfed on the boat. Why did I tell American Marketing Association CEO Bennie F. Johnson this on his podcast?! To illustrate a point about storytelling. And emotion. And the type of authenticity AI cannot conjure. (Also the type...
Nice ALS market map 👇 When precision approaches go broad….looks like yes that can happen. “…a third category being overlooked: 28 programs that are genetically informed but not mutation-restricted. Examples: drugs targeting TDP-43 protein clumps or repeat RNA toxicity. These mechanisms...

There are about 100m Americans with pre-diabetes. But who will progress? Enhanced risk prediction of Type 2 diabetes from a 44 -metabolite signature @NatureMedicine https://t.co/UxmQaD88s4 https://t.co/jhmP3enyTa

How to Build #AIAgents from Scratch by @Python_Dv #AI #LLM #GenAI #ArtificialIntelligence #MachineLearning #ML https://t.co/DCPijpKvrm
Looks like @Mastercard-issued cards still operating for Venezuelan sanctions evasion app @kontigo_app If anyone knows who the issuer is (Rain?) or can share BIN/IIN (first 6 digits), would appreciate it!
The Saudi FDA approved $IBRX Anktiva in lung cancer based on a discontinued randomized study with inconclusive post-hoc data + a non-randomized study with a made-up nonsense responder analysis. These are the data that @DrPatrick and $IBRX tried to submit...

1/ Bioinformaticians get mediocre results with Claude Code and blame the tool. You are doing it wrong. Here's what actually works for genomics analysis: https://t.co/GDOq7SPzla
Learn from my favorite B2B writer’s long (…LONG 😂) career helping brands tell stories around their tech ✏️
Lately I’ve been thinking about how craft is the antidote to ubiquitous AI slop. Quality still matters, and it might even matter more than before when it’s easy to make something mid and hard to make something special. I’ve found...
CasiVision Introduces CASIVIBOT: A Wheeled Humanoid for Smart Factory Inspection by @CyberRobooo #Robotics #MachineLearning #ArtificialIntelligence #ML #MI #Innovation https://t.co/0Nmc67NKuD
So what are you really going to do at your Sales kickoff? I encourage you to listen. Sales, please listen to Marketing. Marketing, please listen to Sales. Think about what you hear and respond with the an attitude of “help...
Serving the underserved is no longer optional for financial institutions. It is the strategy gap holding the industry back, according to this powerful discussion. Watch the full episode now: https://t.co/m6PArSdD2z https://t.co/lwFdWSL0yg