Bayesian Designs Decide Faster than Frequentist Group Sequential Methods
Goal-Driven Flexible Bayesian Design presentation updated w/comparison of performance of frequentist group sequential designs: https://t.co/QCZ6DQrm07 . Frequentist approach takes far too long to make a decision by controlling something that is NOT an error prob. #Statistics #rct https://t.co/X2knbmzTuX
Trump's Drug Pricing Deals Promise Lower Consumer Costs
My @CNBC segment on how President Trump's drug pricing deals will achieve many of the initial aims set out by tariff proposals, with respect to reshoring drug manufacturing, and how the biggest consumer impact in terms of lower drug costs...
Automate Repeated Task Chains in Claude Code
Aim for deeper task chaining in Claude Code. If you find yourself always doing something back-to-back (like using skill-creator and spawning a fresh Claude or two to judge the first one's output), then just bake that in and automate it....
Turn One Proof Asset Into Two Claim Formats
Hot take: your audience isn’t consuming your content. They’re consuming someone else’s screenshot of it. Or a creator recap. Or an AI answer stitched from whatever looked most consistent online at the time. So “we posted 5 times this week”...
Nebius Price Target Lifted to $232 on $5.4B ARR Outlook
Nebius Group $NBIS price tgt raised to $232 at Northland Conservatively raising CY26 ending ARR estimate to $5.4B from $4B on strong 4Q25 incremental ARR and low end of CY26 capex plans. While we are not changing our...
Qualcomm's Rack‑Level AI
I am incredibly excited to see the first shipment of @Qualcomm’s rack‑level AI hardware and software solutions arrive in the Kingdom of Saudi Arabia for deployment at @HUMAIN data centers. This marks a major milestone for our data center business,...
AI Success Requires Human Transformation, Not Just Technology
Why do so many organizations report AI adoption, yet see limited returns? New data suggests it’s not just execution. Fear of becoming less relevant, or even replaced, leads employees to “use” AI without truly embracing it. The real shift? Treat AI...
Know Your Vision First, Then Let AI Amplify
🔥 Hot take: AI won't be effective if you don't know what "good" looks like. You can't simply prompt your way to wisdom—if you lack an understanding of your audience, your goals, or your craft, AI will only amplify the...
AI-Generated Review Spam Overwhelms Feeds—Proceed with Caution
Interesting find and I wasn't even looking for it... Pathetic over-optimized review shows up in my feedly. Gobs of content. Too much. No author listed... Sets off my internal "this looks AI-generated content" flag. Check the page, yep, 99% probability...
Deutsche Börse's Allfunds Deal Fuels Tokenization Ecosystem
Deutsche Boerse's record deal for Allfunds sends shares higher https://t.co/CzVp47tiwL It is an ecosystem play for a Tokenized future. My analysis https://t.co/GcECatMsVJ https://t.co/V39EtHorCX
Peak Capacity Shortage Drives Soaring Electricity Rates
We have been talking about peak electricity demand for several years. There is a smart way to solve it and a "vibes" way to solve it. We won't have a lack of annual energy, we have a lack of peak...
Rewards Drive AI Agents to Abandon Paper Checks
Ya'll realize people (and businesses) still use... paper checks, right? User payment preferences are rarely about fees. Will the AI agents get rewards for using a Colossuspay card? If not, why would their human switch from rewards CC? Bc it helps...
HR Examines $15K Reverse Recruiting Model
$15K to land a job? What HR can make of ‘#ReverseRecruiting’ @HR_Exec https://t.co/WiJQnzc2w6 #HCM #HRM #HumanResources #HRTech #CHRO #CPO #Hiring #Recruitment #PeopleManagement #Culture #Change #FutureofHR #HRCurator
Nonbank Expansion Fuels Money Laundering, Breaches, Weak Oversight
As we see nonbanks getting more and more involved in lending, payments, holding funds, etc. you’re going to see a lot more money laundering, breaches, and data selling with very little regulatory authority to fine or discipline.
Weekly SEO Recap: Google Volatility, Review Disappearances, AI Updates
Catch up on last week with the SEO Video Recap covering the week long super heated Google volatility, Google reviews are disappearing again, links in AI Mode and AI Overviews are updated, Google Ads news and more https://t.co/e9yXgyFhbD
Sitemaps Don't Guarantee Indexing Without Valuable Content
Sitemaps aren't a directive. You still need to prove a site's worth to Google... -> From John: "One part of sitemaps is that Google has to be keen on indexing more content from the site. If Google's not convinced that...
Stop GTM Theater: Focus on ICP‑Driven Strategy
If your GTM looks impressive but revenue is flat, that’s not bad luck. You're stuck in the classic GTM Theater vs. GTM Strategy trap. Let me explain... GTM Theater is when... 1) You've got that Agency running ADs, and they're showing you all the...
Google Admits Indexing Data Gaps Are Just Side-Effect
Google's @johnmu on the page indexing data missing issue - "just a side-effect" - story updated at https://t.co/y7yTnWMPqo https://t.co/Aa09Vs5Avg
Record 2025 Sales Bolster Case for New Satellite
.@OvzonAB: Our combined satellite capacity and mobile terminal sales in 2025 delivered record revenue, profit and backlog. Results add argument to our assessement re: building another satellite to meet demand.https://t.co/j7A2bpoBC9 https://t.co/abyH109gpe
AI Now Handles Text, Images, and Audio Simultaneously
Early AI models could only handle one type of input. Now they can process text, images, and audio at the same time. That's multimodality. Reasoning models work differently. They break problems into steps first. Like a built-in "let's think step by step." Swipe through the carousel...
US Policy Shifts Risk Turning Economy Into Petrostate
The US risk drifting toward petrostate economics. Regulatory rollbacks and clean energy policy U-turns aren’t just about climate — they affect jobs, industrial competitiveness, health and investment certainty. https://t.co/6Jn5YrWN68
Google Ignores Sitemaps Lacking Fresh, Valuable Content
Google won't use your Sitemap file if it isn't convinced of new/important content says John Mueller of Google https://www.seroundtable.com/google-index-sitemap-content-40973.html #google #seo #googleseo #sitemaps
Sell Ideas, Not Time: The Wealth of Ownable Concepts
Top paid experts all have one thing in common: They sell ideas (not just time). And iIdea owners get rich. Simon Sinek charges $100K+ for a keynote today. But before his famous “Start With Why” TED Talk? He was a relatively unknown marketing consultant. One...
Doctor-in-the-Loop AI Enh
Evaluating a doctor-in-the-loop AI-agent for multiple myeloma chart reviews [Nov 3, 2025] Karla Mariana Castro Bórquez et al. @HealthTree #ASH25 abs25-15262 PID 4424 https://t.co/MvBeHqOxCg #mmsm #AI #EMR #RWD https://t.co/onY817NfVr
Histopathology Genomics Predicts Myeloma Risk in 1,429 Patients
Individualized treatment risk stratification using histopathology-based genomics prediction in multiple myeloma: A multicenter Study in 1429 participants [Nov 3, 2025] Rajanna et al. @DrOlaLandgren #ASH25 abs25-11635 PID 4008 https://t.co/gOprMCjfgh #mmsm #AI #oncopath https://t.co/pjikEsgfHC
Race‑agnostic AI Accurately Predicts M‑protein in Myeloma
Race agnostic models maintain accuracy in predicting M-protein levels in multiple myeloma [Nov 3, 2025] @rahul2u et al. #ASH25 abs25-11347 PID 2810 https://t.co/A27ozBoW8h #mmsm #AI #CancerDisparities https://t.co/ubJ6NGMFUE
Unstructured Serum Data Hinders AI in Myeloma Care
Unstructured serum electrophoresis data limits real world AI models in multiple myeloma: Evaluation of 384 institutions across United States [Nov 3, 2025] @MalekEhsanMD et al. #ASH25 abs25-11278 PID 2809 https://t.co/mAC8l7xnaG #mmsm #cancerdisparities #hpeonc https://t.co/veJxBV5S0N
Side Effect Severity Shapes Patient Autonomy in Myeloma Care
Patient-Centered Care in Hematology: How Side Effect Severity Influences Decision-Making Autonomy in Relapsed Refractory Multiple Myeloma [Dec 8, 2024] Martinez et al. #ASH24 Abst 706 https://t.co/l7SHPBwbna #mmsm HT @Taxkourel
Patient‑Driven Platform Accelerates Multiple Myeloma Research
.@HealthtreeMM Hub: A Patient-Derived, Patient-Driven Clinical Cancer Information Platform Used to Overcome Hurdles & Accelerate Research in Multiple Myeloma [3/10/22] @NSweeneyPhd @AhlstromJenny @FaithEDavies1 @mtmdphd @JCOCCI_ASCO https://t.co/WOwLb9Eozv @myelomacrowd #mmsm https://t.co/dZzhU3N32Q
Patient Portal Streamlines Myeloma Imaging and Pathology Reporting
. @HealthtreeMM Patient Portal mediated myeloma patient reported diagnostic imaging and pathology testing - @NSweeneyPhd @AhlstromJenny @mtmdphd J Clin Oncol 38: 2020 (suppl; abstr e20565) #ASCO20 https://t.co/CRLXETpeMm #mmsm #oncorad #oncopath https://t.co/m1UGDimLWm
Low‑dose Dexamethasone Improves Survival in Newly Diagnosed Myeloma
Lenalidomide + high-dose dexamethasone (RD) vs lenalidomide + low-dose dexamethasone (Rd) as initial therapy for newly diagnosed multiple myeloma: an open-label RCT [10/22/2009] @VincentRK et al. @TheLancetOncol https://t.co/hXxlFINejC #NCT00098475 #EAonc E4A03 #mmsm #caxtx #ctsm https://t.co/FjBnt6yIox
Daratumumab Boosts Revlimid Efficacy in Smoldering Myeloma
#EAonc EAA173 - Daratumumab to Enhance Therapeutic Effectiveness of Revlimid in Smoldering Myeloma (DETER-SMM) - PI: @nsc_natalie https://t.co/VtBMJUjI5X Activated: Apr 30, 2019 #mmsm @eaonc #NCT03937635 @VincentRK @mweissmdphd https://t.co/QdWETmSoiR
New Trial Compares Dara‑Bor‑Dex vs Cy‑Bor‑Dex for Myeloma‑Induced Kidney Damage
EAA241 - Ph 2 RCT Dara-Bor-Dex vs Cy-Bor-Dex in the treatment of Newly Diagnosed Multiple Myeloma with Light Chain Cast Nephropathy (LCCN) [Study activated 8/11/25] @keruakous https://t.co/1NgvVZ3fTA #NCT07085728 #mmsm @eaonc https://t.co/paGRlHV1Dv
Search Spikes Don’t Harm Google Search, Says John Mu
Google's @johnmu said a spike in search impressions does not cause problems with Search https://t.co/Gx8bDf2WoW https://t.co/cLxH8TBMF9
Economists Needed to Assess AI’s Macro Economic Impact
We need real economists (@ModeledBehavior, @arpitrage, @tylercowen, Krugman etc) to take a crack at the fast AI scenarios from an NGDP, RGDP, productivity growth, inflation, 30,000-foot macro standpoint. What are the tech/VC/hedge fund people missing?
Local Content Rules Halve EV Subsidy Effectiveness
New @nberpubs: "Industrial Policies for Multi-Stage Production: The Battle for Battery-Powered Vehicles" https://t.co/DX6XB7e1R0 "local content requirements... drive up costs and reduce subsidy uptake, undoing more than half of the EV adoption stimulus coming from pure buyer subsidies" 😲
AI Threatens Jobs, Forces Us to Rethink Food Allocation
Think you might be getting a bit ahead of yourself here... If AI makes human labor obsolete, who decides who gets to eat? https://t.co/3kx7WjAcRC
Bandages Evolve: From Passive Cover to Active Healing
Bandages have been a central component of wound healing for centuries. In the digital health era, the wound healing process will transform the role of bandages from a passive to an active one. We dive into the current and future innovations of...
Top Recruiting Trends Unveiled in Issue 256 of This Week, In Recruiting
Check out the latest article in my newsletter: This Week, In Recruiting - Issue 256 https://t.co/XcJqoF4avU
General Atomics Names Fighter Drone “Dark Merlin”
Dark Merlin Is Now General Atomics’ YFQ-42A ‘Fighter Drone’s’ Nickname Merlins are small but fierce birds that attack in groups and are known for their stealthy attacks. https://t.co/H0oZhFL1j9
Critical Thinking Must Outpace AI in Healthcare
Jan Herzhoff, president of global health businesses at Elsevier, emphasized the importance of critical thinking over sole reliance on AI to prevent de-skilling in healthcare at the India AI Impact Summit 2026. https://t.co/hexOguFdCt #AI #Elsevier #health #India
Skip Semantic Layer Early; Use Native Metrics First
Controversial opinion: don't start with a semantic layer. A semantic layer makes sense when: - You have multiple consumers (BI, notebooks, apps) - KPIs are defined inconsistently across teams - You need a universal API for metrics If you're early stage with one BI tool,...
AI ROI Proven, Yet CIOs Lag Behind
The AI ROI is Real, But Are CIOs Ready? Insights from Lenovo’s 2026 Playbook by @Timothy_Hughes https://t.co/EMAEj0YnH9 @DLAIgnite #SocialSelling #DigitalSelling #artificalintelligence #ArtificialInteligence #Technology #Innovation #Tech #TechNews #Leadership #Cloud #CloudComputing #SaaS
AI Drives Intelligence Cost to Zero, Human Cognition Devalues
This is an interesting scenario like AI 2027 and in line with my book https://t.co/R8VoeGs69Q However one thing under appreciated is that the cost of useful intelligence is going to 0 & value of human cognition is going negative https://t.co/s2JNhGmxyd
James Tour's Laser‑Induced Graphene Powers New Artwork
📰 🧪 James Tour Group in the News: An article featuring Joseph Cohen’s artwork mentions that was created at Rice using laser-induced graphene, a technique pioneered by James […] https://t.co/QipzjwJuap
Critical Thinking Beats Prompt Engineering as 2026 Moat
Hot take: The most valuable skill in 2026 is not prompt engineering. It is critical thinking. Claude 3 Opus tops out at 70% on causal reasoning. LLM accuracy drops as data gets fresher. The humans who never outsourced their judgment? They are now...
Insurers' Biggest Hurdle: Leveraging Tech for Incumbents
Which is insurers major challenge ? → https://t.co/YWi9QjcUaF It's not a matter of innovation per se but how tech could benefit incumbents. https://t.co/bJYiaUkE4h
Prediction Powers AI: Master It for Business Edge
Prediction is not just a human trait; it’s the foundation of AI. As we harness artificial intelligence, we’re tapping into our natural ability to foresee patterns and trends. Leaders who understand this can leverage AI to their advantage and drive smarter decisions. In...
Robot Competition Heats up as New Rivals Emerge
Hey @Tesla_Optimus your competition is growing. Damn impressively too. Yes, I know that they aren't generalized. Or safe enough to bring into our homes. But wow. What a show. Hey @cixliv I could see multiple robots...
Samsung Turns Phone Into AI Switchboard, Redefining Competition
The AI battlefield just moved to your pocket. This week, Samsung expanded Galaxy AI on the new Samsung Galaxy S26. I have been watching the AI race closely, and this move stood out. On one device, you can now tap into: → Perplexity...