Sanofi's Board Ousts Hudson, New CEO Faces Dupixent Gap
So Sanofi's board strikes again. Paul Hudson gets the old Paris boot 6 years after taking on the task of remaking the pipeline. It hasn't gone well. Next: Belen Garijo. She has a few years to get ready for the post-Dupixent era. Not easy. Great to have a giant cash cow, hard to line up new ones. https://t.co/xIA6r2BpRq
Choose AI for Purposeful Creation, Not Just Task Automation
Reading this essay made me ask myself a question: am I using this to „do the thing“ or just to „do a thing?“ Interesting nuance here. I personally use AI very much as a deliberate tool, both in building & running a...
Narrowing Focus Revives Growth After Overexpansion
Are you justifying 'how our product's different' on every sales call? There’s a reason and a counter-intuitive solution: Gilles Bertaux's company experienced this firsthand. They grew from $2M ARR to $9M ARR in one year during COVID. But then they almost lost...
Meet Your Audience Where They Live, Then Speak
When you need a message to resonate, start with the right questions. Who is the audience in this moment? What are they thinking about on a normal day? What do they care about when they wake up, go to work,...
AI Is Already Simplifying Online Scams, Experts Warn
AI is already making online swindles easier. It could get much worse. Some cybersecurity researchers say it’s too early to worry about AI-orchestrated cyberattacks. Others say it could already be happening. #fintech #tech #finserv #AI @BetaMoroney @efipm @BrettKing @spirosmargaris @jasuja @enricomolinari @mikeflache https://t.co/xbcVW86X8z
FDA Defends Skipping Review of Moderna's mRNA Flu Shot
FDA defends its decision not to review Moderna's mRNA flu shot. My comments with @NBCNews @BerkeleyJr https://t.co/h8PlaEUC3v
Teaching What You Learn Turns Struggle Into Mastery
I failed to complete my PhD. But I discovered something 10x more valuable along the way... In 2019, I was a Systems Engineering student who loved math. And I fit the typical stereotype for people in my area of study: - Quiet - Nerdy - Introverted -...
Nebius Q4 2025 Earnings Reveal AI Infrastructure Growth
Nebius, an AI infrastructure business, just released their Q4 2025 earnings. Here’s everything you need to know at a glance:
ASCO GU26 Highlights Litespark, Keynote B15, Flare
Key late-breakers at Asco #GU26 include Litespark-011 & 022, Keynote-B15... and who's heard of Flare Therapeutics? Via @ApexOnco -> https://t.co/bXcANMQu5m $MRK $PFE $ALMPF $CGON $VIR
Vulcan Launch Shows Possible Solid Booster Nozzle Failure
🚨 Vulcan Problems: Today’s ULA Vulcan launch from SLC 41 seems to have had some sort of solid booster problem. Possibly a nozzle burning through. The only official word from ULA is that they’ve made an “observation”. The sparks are clearly visible in...
Ex‑Trenchant Exec Sold Internal Hacks to Russian Broker
Former exec at exploit development firm Trenchant, owned by L3Harris, admitted to selling internal hacking tools to a Russian broker. Did the company notify the vendors whose products were exploited so that they could be patched? https://t.co/4wKJgZoIkl
EU Parliament Backs Digital Euro to Curb US Payment Dominance
Post-Trump assault on Greenland, the EU parliament delivers a big win for the digital euro as it wins 420-158 backing in EU Parliament straw poll The digital euro couldn't have better timing as the EU looks to the digital euro...
Batch 30 Days of Content by Filming Reusable Clips
If you want to batch 30 days of videos fast, stop filming full videos and start filming reusable clips.
Start AI Support Early to Scale Customer Experience
A lot of people think Fin is only necessary when you're "at scale" and until that point you should do your own support. I understand the thinking, but it misses out of what your customer's experience is. The reality is...
Bad Tools Drive Talent Loss and Competitor Advantage
Give engineers subpar tools, what could possibly go wrong? a) competitors out-ship AWS (eg Vercel, where Claude Code is used by so many and they are on 🔥) b) frustrated engineers interview elsewhere and take offers at places where Claude Code or...
Teach First, Offer Later: Simple Phrase Calms Audiences
You’re allowed to say, “I’m going to teach first, then I’ll share an offer.” That one sentence relaxes everyone.
AI Polishes Everyone, Erasing Unique Voices
Something honestly scared me today. I was scrolling LinkedIn and I couldn’t tell who wrote what anymore. • Same tone • Same structure • Same “smart” voice I use LLMs every day. I love them. But here’s the part nobody says out loud: LLMs don’t just help...
Stash Sold for $425M, Far Below $747M Raised
Ouch. Stash selling for $425MM after raising $747MM As a founder who has met a liquidation preference once in a while, this is PTSD. It is a tough hurdle to raise so much and then return the capital. Am sure the team...
Quantum Software Alliance Launches Site to Accelerate Practical Computing
Quantum software is essential to make quantum technology work. The #QuantumSoftwareAlliance is a network of research institutions focused on making quantum computing practical through software, with an emphasis on co-design, algorithm discovery, verification, benchmarking, and interoperability. The web page is now...
AI Safety Lead Quits, Warns World Spiraling Apart
My morning headline: Anthropic’s AI safety lead quits, saying the world is drifting into peril as our values and actions keep diverging. Just a casual day in 2026. https://t.co/xHc7rZBTzE
1994 Lillehammer Winter Olympics Suffer First Major Cyber Attack
On this day in 1994, the winter Olympics in Lillehammer were hit with a cyber attack. https://t.co/AZfPpQUjAr https://t.co/xox3MFDt75
Proton Rocket Launches Elektro‑L5 Weather Satellite From Baikonur
Proton rocket lifts off from Baikonur, Kazakhstan, with the Elektro-L5 weather satellite. DETAILS, UPDATES: https://t.co/XRGzszk0qi https://t.co/3ZESECT8GH
Run OpenClaw Securely in the Cloud, No Setup
You don't need a Mac Mini to run @OpenClaw. Use https://t.co/jeP0nebHIv instead. With it you can safely run OpenClaw in the cloud. It's always on, so you can finally close your laptop without killing your agent. You can join the OpenClaw revolution...
Shift From Tech Fixes to Economic Agility with Agentic AI
Most companies don’t have a technology problem. They have an economics problem. That’s why this extract stayed with me. In this conversation with Mike Sutcliff, CEO of Thoughtworks, he names what many leaders feel but rarely challenge. As he says: “𝐖𝐞 𝐧𝐞𝐞𝐝 𝐭𝐨 𝐞𝐧𝐚𝐛𝐥𝐞 𝐚...
China's CO2 Em
NEW ANALYSIS: China's CO2 has now been 'flat or falling' for 21 months * Down in 2025 * Still below Mar 2024 * Clean energy wave a key factor If this is China's peak (TBC) it's the climate story of the century so...
Ripple Secures Full EU E‑Money License in Luxembourg
Ripple Granted Full EU Electronic Money License in Luxembourg - Fintech Schweiz Digital Finance News - FintechNewsCH https://t.co/qV8sL92Tof https://t.co/Cczo1Sx4QO
Own Your Brand, Work It, Grow Exponentially
Kevin Hart built a tequila brand in a declining market and grew it 85% in one year. Gran Coramino sold 300,000 cases, passed $200M in retail sales, and became a top 25 tequila worldwide. He joins weekly sales calls, meets distributors, and...
Robots Should Adapt to Humans, Not the Reverse
This is the kind of robotics progress I care about. Toyota introduced Walk Me, a walking wheelchair that climbs stairs and handles rough terrain instead of relying on wheels. The point is independence. Moving through the real world as it is, not as...
Voice‑First Tools Are Redefining Workspaces and Productivity
Voice is exploding. I talk to Claude Code and other tools almost exclusively in voice and screenshots. Office spaces are changing and will continue to change because of it. I can’t work for long periods at certain places because I...
Continuous Batching Eliminates Slow AI Chat Bottlenecks
Why Your AI Chat is Slow (Static Batching) ⏳ Static batching means one slow request blocks everyone else for seconds. Here is how Continuous Batching solves the "slowest user" problem #Coding #DevOps #AIModel #Latency https://t.co/CRe945HeYs
CIOs Learn to Extract Value From AI Investments
Our fourth episode together. I'm thrilled to be back on @CXOTalk with # @tcrawford to guide CIOs on getting value from AI investments. Join Friday at 1pm ET -> https://t.co/xTvbca0YxB #CXOTalk #AI #GenAI #CIO https://t.co/K1bs8u1afg
Electric Cars Make up 3.5% of Jan Sales
🇮🇳About 3.5% of total passenger cars sold in January 2026 in India were electric (these are actual cars and do not include two- and three-wheelers).
Adopt Only Tools That Boost Output 30%+
Every week a new AI tool goes viral. Every month half of them die. Stop falling for it. Before adopting anything, ask one question: "Does this give me 30% more output, savings, or speed?" No → move on. Yes → go all in. I've watched founders waste...
Texans Use More Power, Paying 28% More Per Capita
Despite CA having 2x the elec price as TX, Texans pay 28% more per cap for elec yearly because TX uses 2.7x the elec per cap as CA (vs 2.1x in 2001, so nothing to do with weather) even with...
GLM‑5 Surpasses Gemini 3 Pro on Intelligence Index
GLM-5 is now the highest-scoring open-weight model, ranking above Gemini 3 Pro on @ArtificialAnlys’ Intelligence Index 🤯 https://t.co/2zWxmZSYV0
Grid Batteries Displace Fossil Gas, Australia Leads
HEY FRIENDS A rare treat: I'm talking about something not only good but so good that it makes the cynics and climate delayers look amusingly silly. Big grid batteries are pushing dirty, expensive fossil gas out of the power grid,...
Recruiters Overlook Security While Demanding Identity Verification
I just saw a Recruiter say "people share their data with every app out there, I don't understand why adding extra security layers to the ATS asking people to verify their identity is a problem."
Beacon AI Showcases Pilot Assistance Autonomy Beyond Symposium
Outside of the Special Air Warfare Symposium, how Beacon AI is touting pilot assistance autonomy https://t.co/AK7QFrzgvz
First Like Drives Clicks, Later Likes Lose Power
RT @Frank_Strong "A new Journal of Marketing study finds that the first like on a social ad has a profound impact, significantly boosting both clicks and likes. However, as the number of likes increases, their influence on clicks diminishes." ...
Heat Pumps Cut Gas Use Even with Gas‑generated Electricity
Most people don’t know this: Heat pumps REDUCE gas consumption even if running 100% on electricity from a gas fired power plant. More here in my piece for @CarbonBrief 👇 https://t.co/rKlRE0ug1S https://t.co/DTnKDp9lZp
Claude as Thought Partner Uncovers Hidden GA4 Insights
[VIDEO walkthrough] - Here's me asking Claude about my GA4 data, I got a thought partner surfacing things buried in my data that I didn't even know was there. In my "data chat" with Claude I found: 📈 Notebook LM was a...
90% Want Free AI Mammograms, Yet None Receive It
Over 90% of responders believe it's time for mammography to incorporate AI for every readout, whereas close to 0% who get screened are getting that interpretation now, and at no out-of-pocket charge https://t.co/hITOBNd7pg https://t.co/x1I6Ffxfio
Nvidia Chips Generate $8‑10 Economic Ripple per Dollar
"When I look out over the next two, three years, a ripple effect for every dollar spent on $NVDA chips, there's an $8-10 multiplier across software and infrastructure" 🎙️ @DivesTech joins Dan on the latest Okay, Computer. https://t.co/kyBad40Wln
AI Personas Turn Weeks of Work Into Seconds
What took me a week to build out a year ago just took me about 15 seconds. Since late 2022, I've been assigning personas to LLMs to have them poke the hell out of my work. "Review this product launch...
Algorithm Shift Cuts Blog Traffic, Boosts AI Citations
I've been looking closely at organic traffic trends vs. LLM citations: The below site's blog was hit by recent algo changes: 1st screenshot: organic traffic to blog 2nd: ChatGPT citations to the blog 3rd: AI Mode citations 4th: AI Overview citations https://t.co/1bSsAAUsWh
AI‑Powered Wealth Management Meets Human Expertise
probably a good time to announce that there’s a better way: @clovefi a new uk wealth manager that combines ai with the best of human advice. https://t.co/Nz9FBbJgnQ
OpenClaw + GPT5.3 + Opus 4.6 Supercharges Productivity
I'm one of the most advanced users of OpenClaw. OpenClaw + GPT5.3 Codex + Opus 4.6 has been the trifecta that changed everything. I made a video going over everything I'm doing with these tools. Learn these tools, stay ahead. Watch this...
Zero‑Click Buyers Push B2B Marketing Back to Fundamentals
B2B marketing is in a wicked transformation. Buyer behavior exposes the fallacy of the obnoxious idea that B2B buying follows a funnel. Traffic to your website is down because buyers are asking LLMs for answers to their questions. Your email...
Scientists Overstate Precision by Ignoring Significant Figures
Pet peeve: why do "scientists" forget about the concept of significant figures? Happens all the time, in biotech & beyond. Too many decimal places scream lack of credibility. "Sig figs" is a simple concept: measurement readings should not push beyond instrument...
Vercel Sandbox Adds Simple Network Isolation Support
Vercel Sandbox isolation levels: ✅ Compute & memory resource isolation ✅ Filesystem and durability isolation 🆕 Network isolation Wild how easy this is: --𝚊𝚕𝚕𝚘𝚠𝚎𝚍-𝚍𝚘𝚖𝚊𝚒𝚗 (CLI) or 𝚗𝚎𝚝𝚠𝚘𝚛𝚔𝙿𝚘𝚕𝚒𝚌𝚢 in 𝚂𝚊𝚗𝚍𝚋𝚘𝚡.𝚌𝚛𝚎𝚊𝚝𝚎. Try it out: https://t.co/UoWXCW9Ien