
Claude and ChatGPT have very limited memories So I decide to build one with an infinite memory To remember everything about your business, goals, plans, etc. Try it and LMK what think -> https://t.co/KDuiuVY1GI https://t.co/4uuvWjUo8J
NASA's annual Spinoff report -- Spinoff 2026 -- is out, celebrating its 50th anniversary. https://t.co/nXOeQdaTn7

Continuous glucose sensor (GGM) foundation model predicts Type 2 diabetes and cardiovascular deaths better than the standard blood biomarker, HbA1c
If you keep saying “I don’t have time,” start with a 2 hour offer. Time is not the issue. Decision is.
NASA says the Artemis II Wet Dress Rehearsal is now as early as Jan 31. https://t.co/bj6ypJWE9L
Of course @tiktok_us is building world models to run robotics, and other things. An effort to watch.
Now your AI agents can do customer research by using simulated humans that are based on real humans. In other words, a new way of building your business is here. @runrehearsals cofounder @liambolling gives me one of the most interesting conversations about...
Your competitors are sending their whole leadership team to SaaStr AI 2026. You can skip it. But don't be surprised when their AI roadmap is 6 months ahead of yours by June. May 12-14. SF Bay. https://t.co/4U2DOAE1gc
The AI researchers are emulating the human brain and here's an interesting report about it. (From my neuroscientist list).
Replit is now known as one of the fastest-growing AI companies in the world, but what's less recognized is our adoption in the enterprise. Our sales team officially started last year, and since then we've closed some of the largest...
Still no date for the WDR or launch, but Artemis II crew is getting ready. They entered quarantine on Friday in Houston. Pending outcome of the WDR or other operations considerations they can come out and reenter 14 days before...

$60CPM's... No conversion tracking... "confident in unique ad value despite limited analytics" Ugh. Brands need to learn from AppLovin's rollout to new ad channels. https://t.co/v4qSx7wveH
Attention Ph.D’s!🚨🔔 Registration for the CMU 3 Minute Thesis Competition ends next week. All Ph.D students regardless of year are welcome to compete. Get started below 👇👇 https://t.co/yXFM6UMc0q https://t.co/dsVieQDeWI
My biggest takeaways from Jason Cohen : 1. “Too expensive” is never the real reason customers cancel. They already saw your pricing and decided to buy, so something else changed. When customers cite price, dig deeper—the actual reason might be changing...
I'm a co-investor with a mega VC fund we don't talk about as much here but they are wildly successful in many top IPOs and top decile returns. And they have a really simple way they do follow-on checks: ✅If the company...
The Sultanate of Oman is the latest Artemis Accords signatory. Oman is hosting the Middle East Space Conference this week. https://t.co/vdZQAZ2n6w
Hospital group seeks to have new Eli Lilly policy on 340B claims data blocked https://t.co/Uz0lDrgL1y
Zoom is up 10% today, or about what its Anthropic position would be worth (I'd guess closer to 50x than 85x). It's trading at a $28B market cap as of right now, and its Anthropic position is probably worth ~$2-3B. Insane this...
I had a friend recently ask me if he should run ads for pre-orders while he's out of stock until March. His raw material sources are backed up from Chinese New Year, and he can't manufacture again for weeks. But when it...
After 15 years heading The Planetary Society, Bill Nye "The Science Guy" is transitioning from CEO to a new role as Chief Ambassador as well as Vice Chair of the Board of Directors. Current COO Jennifer Vaughn will be...

That *is* an excellent report abt the realities of spacewalking on the Moon, esp v the ISS, and Axiom's suits. Incl stmts by astronauts Kate Rubins (ret) and Mike Barratt to the Natl Academies recently (plus an interview w/Rubins). Snip:...
GEO anxiety is the new FOMO. And it's everywhere. We just surveyed 50 mid-market B2B marketing leaders through Wynter platform. Everyone is scrambling to figure out AEO/GEO. Why? Because the old playbook is bleeding out. 46% of these leaders are actively pulling back...

Canada's @MDA_space and Korea's #Hanwha Systems Co sign MoU to explore collaborating on Korean govt K-LEO military constellation using MDA's Aurora software-defined satelite platform. https://t.co/6vSjdppt4v
My friends at Pragmatico are hiring a Head of Content Marketing, and it's a super interesting role. Outside of working with Randy Stocklin and Santiago (Santi) Jaramillo (which should be enough), this is a super interesting role because it's more than...
Claude now supports MCP Apps, which means you can get interactive experiences in Claude responses. We're excited to partner with Anthropic to support Box file previews for nearly any file type directly in your Claude chat experience.
Every founder should be creating content and that’s a hill I’ll die on. Your content is a landing page for literally everyone. - Investors - Agencies - Partners - People you want to hire They are all going to your profile to figure out what...
Nailing the first sales hire has historically been one of the biggest hurdles in kicking off the scaling process. They’re a unique breed: half Account Executive, spending all week in conversations with prospective customers, and half Product Manager, distilling those insights...

very excited to share a project i've been iterating on for 3+ years: an AI-powered startup "accelerator" inspired by my time at Techstars and seeing similar programs, I've wondered what an AI-first version could look like check out what i made this weekend...
I've been watching this company since its very beginnings. Back then it could barely make blurry photos with hands that had an unnatural number of hands. I tried to get some investors interested in it and they passed. Now 4x faster...
High-speed food packaging only makes sense if automation actually changes the economics. At Anı Bisküvi A.Ş., a robotic box-filling system from Robentex now runs two lines at a combined 800 products per minute. They moved to a tray-and-lid concept instead of classic...
Bombas made $100M selling socks with ONE differentiator: donate one pair per purchase. Meanwhile you're adding 15 features nobody asked for. That's the gap.
The Adolescence of Technology: an essay on the risks posed by powerful AI to national security, economies and democracy—and how we can defend against them: https://t.co/0phIiJjrmz
I’m building the next billion-dollar SaaS. (At least that’s the goal) I’m documenting the whole thing so you might be able replicate it. Welcome to episode 1.
Will IonQ really allow other QC companies to use SkyWater, as the press release claims? What if someone asks to tape out a device superior to what they have at a given time?
🧠 The ABC of AI use cases is useful—but incomplete. Lists like this help name opportunities. Leaders need help prioritizing and sequencing them. Here’s the strategic reframe: 🔹 Most use cases collapse into 4 enterprise intents 1. Predict (risk, demand, churn, downtime) 2. Optimize (costs, workflows,...
A number of Washington Post journalists asked for tips from government workers last year and posted their personal phone numbers for @signalapp. Please know that Signal allows you to create a username, meaning you can keep your phone number private....
I think you should always listen to Peter Sandman, even if you don't agree. "Shared decision-making on vaccines is not the enemy," one of the great experts on medical decision-making writes in STAT. https://t.co/1XZnI9JZ1m
AI is getting better at answers. The next step is knowing when not to rush one. New research argues for artificial metacognition: giving AI systems the ability to reflect on their own thinking, detect uncertainty, spot conflicts, and slow down when...
Rahul warns us about Clawdbot. I'm not too worried about the nerds here who load it, but it got so popular over the weekend that non-techies will get drawn in. And that's where the trouble starts. I don't know how...

I don't know how to ask for a moment of silence amid the madness that is X. But please take a moment to reflect on the heroism of William Foege. Foege, who died Saturday at 89, was a key architect of...
Developers: fresh meat. Added to my AI developer tools list. Now more than 1,400 companies. My friends say this one is a good one, will it get you to change off of Claude?
As @jasonlk said a few days ago, it won’t be long until most of us have at least one agent working for us almost 24/7. More and more, I give an agent (usually coding or research) a task before jumping on...

.@defis_eu Iris2 multi-orbit network expands low-LEO component to allow more industry experimentation; @esa agrees to modify its rules to permit reimbursement of NRE expenses needed to scale tech to constellation-level production rate. https://t.co/oxaKaZk6Vf

NRF is drowning in “AI for fashion” demos, from styling assistants like Ask Ralph to one-click shopping via Copilot/Gemini/ChatGPT. Do customers want this… or is it just retail tech cosplay? If AI doesn’t reduce returns or improve trust, it’s innovation theater. https://t.co/Lym3BLrso4
A recent Science #Robotics study describes an interlaced origami-based structure that enables mobile robots to extend arms to press elevator buttons or form frames to support heavy 3D printing systems. https://t.co/fgD4ZjcnPp https://t.co/M4GVUcZKYH

.@OHB_SE confirms it's in talks with @RheinmetallAG "regarding a cooperation for participation in possible public procurement processes," which @handelsblatt reported was the proposed multi-billion $ broadband constellation for the German @bundeswehrInfo. https://t.co/npkoQGwWoo
I’m gonna be honest about Clawdbot. I’ve seen dozens of tweets on it, watched tons of videos, read whatever docs and guides I could find, and I’m with @omooretweets on this one. I’m glad tinkerers are loving it. I’m glad...
This is good news indeed. Ethiopia has declared its first recorded #Marburg outbreak is over, after going 42 days without new cases. There were 14 confirmed cases & 9 deaths.
Kontigo looks and acts like a neobank, but there’s no bank standing behind it. At least with BaaS middleware, the end user had a legal and contractual relationship with a bank. So, there's a clear line of responsibility (whether the issue was...
Most B2B SaaS companies are sitting on a goldmine. (they just don't know it). Here's what I see: A customer gets their first win. They're excited. They tell their team "this works." That's a wow moment, but nobody captures it. Marketing keeps spending $50K/month on...