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In this episode Marc Andreessen, Erik Torenberg, and Replit CEO Amjad Masad explore how AI agents are reshaping programming, arguing that English‑based prompts are becoming the new coding language. Masad explains how reinforcement learning unlocked reasoning in large models, how verification loops enable reliable code generation, and why "good‑enough" AI could both accelerate and hinder progress toward true general intelligence. The discussion also traces computing history to the rise of agents that can plan, reason, and write software autonomously, and highlights Replit’s platform that lets anyone build complex applications via natural language. Overall, the conversation paints a future where software writes software, shifting the developer’s role toward prompting and orchestration.
"When we started a16z, we decided we wanted to treat venture as not only a craft, but also a product, and staff an organization set up for that goal" - @pmarca David is the best "venture as a product" builder I...
What I see CEOs at struggling start-ups do: - Go dark - Hide - Lash out - Tweet about lots of things non-work - Invest time on tiny expenses - Argue internally What should do: - Be Present - Be Honest - Be the Rock - Be Realistic/Optimistic You just plain grow...
Venture investor Tomasz Tunguz argues product-market fit (PMF) is no longer a one-time milestone but a continuous condition because rapid advances in AI are constantly reshaping customer needs and technical possibilities. He points to firms that lost PMF between 2021–2024,...
1. Excluding SpaceX - We have 30%-40% of our venture portfolio here. 2. Tel Aviv feels like the MOST exciting city in the world right now. There is an electricity...and it is inspiring! 3. Golden Age for the region. 4. Israel is defending...
When people trust humans, they trust intent. When they trust AI, they trust transparency. The best AI agent interfaces will reveal complexity with clarity. A good experience helps people see how an agent thinks, not just what it does. That’s how confidence...
TechCrunch Disrupt 2025 kicks off in San Francisco October 27–29, with last‑minute ticket discounts offering up to $444 off and 60% off a +1 pass ahead of price increases at the door. The conference expects 10,000+ founders, VCs and operators...
👀 @ChaseLochmiller and team @CrusoeAI are an unstoppable force that’s enabling the greatest infrastructure buildout of our lifetime. And it’s still early innings! $1.4b in fresh capital, let’s go! https://t.co/p8Hp8XVdGA
New!! "Who Will Buy The SaaS Companies?" https://t.co/m1tppdUsFM
In this episode, a16z partner Anish Acharya and host Kevin Rose discuss how AI is sparking a new consumer technology renaissance, emphasizing that the next wave of products will blend emotion, utility, and creativity rather than just code. They explore...
Just did a deep dive with @mariogabriele for The Generalist. The core idea: great seed investing isn’t prediction: It’s noticing the faint whispers from those already living in the future. 7 takeaways from that conversation. 🧵
It’s time. It’s time to get ahead of the pack in AI + B2B. Not next quarter. Not next year. Right now. Because the companies that figured out AI in GTM over the past 12 months are now scaling those...
Doctours founder Girum shares his personal experience with medical tourism that saved his brother, launching a marketplace that matches U.S. patients to vetted overseas clinics, starting with elective hair‑transplant procedures in Turkey. The platform handles patient intake, clinic verification, reviews,...
We're back! @HarryStebbings @rodriscoll + me: 🧵 1⃣The Great VC Shuffle: Benchmark's big hire 2⃣Why billion-dollar ARR companies that are "still early" 3⃣Why the smartest money might be doubling down on winners instead of hunting for the next big...
AI + video = huge market. This tool on @acquiredotcom helps creators generate and schedule short-form videos automatically. You can spin up YouTube Shorts, TikToks, and AI-style clips (even Pixar-like animations). Zero editing skills needed. > $107K TTM revenue > $79K profit > 100+ customers >...
The post is a EUVC roundup that first features Matti Rönkkö of Kiilto Ventures arguing that family capital, deep industrial expertise and a sustainability focus can reshape the built world. It then shifts to Kristaps Ronis of ION Pacific, who...
Congrats to @Saturn__OS on their $15M Series A! Saturn uses AI to automate compliance and admin work in UK financial advisory—cutting tasks that once took paraplanners 4 hours down to 20 minutes of review. This drops the cost to serve from £2,000...
Somewhere along the way, growth stopped meaning progress and started meaning more. More features. More dashboards. More categories to chase. Every successful product faces this moment. You build something people love. It works. Then comes the temptation to widen the story....
The episode spotlights several deep‑tech and angel‑investment stories, beginning with Charlie of Temperate who converts heat to light and beams it into space, offering a refrigerant‑free cooling system up to 20× more efficient for data‑centers and HVAC markets. It then...
BoxGroup is excited to continue to be in the business of funding early stage ambitious founders building products they dream about - we've raised two new funds, each $275m, to give to founders as early as possible BoxGroup More here:...
Many of the private SaaS founders we work with don't realize that recognizing revenue in accordance with principles of GAAP and accrual accounting is not just a practice for publicly traded companies. We've found that SaaS founders, for convenience and...
In this episode, host Prashant Choubey talks with Ganesh Padmanabhan, founder of Autonomize AI, about the emerging role of AI agents in medical practices. They explore how autonomous AI assistants can handle patient triage, appointment scheduling, and routine follow‑ups, potentially...
My single best investment from 20VC Fund I broke advice everyone gave me. Don’t write small checks. If it is less than 1% of the fund, it won’t move the needle. Wrong. I wrote a $50K check. Today it is...
Ruth from @VendrHQ is the AI negotiation agent for SaaS. Trained on data billions in spend data, she helps you benchmark prices, plan negotiations, and save money. https://t.co/7Y962NhyWR https://t.co/7mYfR4sVsy
On The Bear Roars podcast, Dan Caruso and guest explored how advances in AI, quantum computing and robotics are reshaping not just technology but learning, leadership and collaboration, with a central claim that equitable access — broadband, curiosity and freedom...
Even a terrible startup idea can turn into a great one with the right team.
Mulligan (https://t.co/KlkcVLe0fK) is an end-to-end AI automation platform for commercial insurance brokerages. It can quote, generate submissions and proposals, compare policies, and more. https://t.co/JgQmbPdU3T Congrats on the launch, @araghuvanshi2! https://t.co/onyFYz8ylh
A simple, reusable financial forecast model — with a free Google Sheets template — is presented as essential for startups to project cash flow, prioritize spending, and guide fundraising and hiring decisions. The model focuses on five core sections: customer...
Every major platform shift rewrites the playbook for founders and investors. Sarah Tavel saw it during the rise of mobile — and now knows that to truly excel in a new era, you can’t just observe from the sidelines. You...
AI is a pretty big threat to CRM. Not the need for CRM, but to its value proposition. I didn’t totally get it until we deployed 11+ AI Agents. But what they do is push your CRM to the background....
TechCrunch revealed the full Disrupt Stage lineup for Disrupt 2025, headlined by 200+ sessions across five stages and marquee appearances from Alphabet moonshot chief Astro Teller, Microsoft CTO Kevin Scott, Netflix CTO Elizabeth Stone, Vinod Khosla and Sequoia’s Roelof Botha....
If Adaption Labs is right, the next leap forward in AI won’t come from trillion parameter models, it’ll come from systems that learn on the fly. https://t.co/t4EXiWHf8Z
Congrats to @akeed23, @twopac, and @cerclihq on their $12M Series A! Cercli is the single platform for enterprises to hire, manage, and pay their global workforce in the AI era. They've grown 10x over the last 12 months, processed over...
In this episode, a16z host Martin Casado interviews Kong co‑founder and CEO Augusto "Aghi" Marietti about his journey from a Milan garage to building a leading API infrastructure firm, highlighting the relentless grind, near‑death moments, and the bootstrap funding that...
One of the best CEOs I know said to me the other day, "I wish we'd never allowed work from home I know this is a complex issue even today, and for many, a triggering one. What I can tell you in...
I love simple tools like this on @acquiredotcom. Manage team emails directly inside Slack. > $22K TTM revenue > $20K profit > 200+ customers > Runs on autopilot > Lean, profitable, dead simple Full listing: https://t.co/b3BlAnxTAb https://t.co/1DDfmVFl2z
well put (on eu vs us) “When you build something ambitious, you realize geography isn’t neutral. It either multiplies your luck or quietly kills your momentum. I chose to go where luck compounds.”
Finalizing our next LP update with @vedikaja_in. It's nearly 6,000 words. Maybe we should ask Chat to generate a shorter version for "2x podcast people". 🤔
MarkIt is building AI agents for trade compliance—helping suppliers, importers, and customs brokers classify products, manage documents, and navigate government requirements. https://t.co/tTaCTxaPR9 Congrats on the launch, @ch6nkim and @supadupacoda! https://t.co/cxhpOAGgFV
"At Deel, we do two types of acquisitions. 1. Buy an asset in our core market. Buy the team, revenue, bring them in-house, rip and replace their infrastructure with ours pretty fast. 2. Buy smaller companies that are in adjacent...
Every founder faces moments where they’re not sure what to do next — such as how to go to market with AI products, when to pivot, and who/when to hire. In this episode of Office Hours, YC partners @koomen, @bradflora, @dessaigne,...
Congrats to https://t.co/c9C4WZdYZj on their $10.6M Series A! Letter AI's enablement platform helps sales teams ramp up faster with AI-powered training and coaching, instantly find and personalize collateral for customers, and engage their buyers. https://t.co/mX4rRd1JVo https://t.co/mIGGfzxkUE
Early on traction is a story problem, not a metrics problem. The best founders know which narrative unlocks the next stage.
VC irony: We preach agility, yet often take forever to respond…
Tempo (@Tempo_Labs) has raised $5M to build the best design tool for design engineers. Unlike other vibecoding tools, Tempo integrates with any React codebase and allows designers to control every pixel by hand. Congrats to the team! https://t.co/GmPMka8o0H https://t.co/27HsMZBzkd
Wondering how you stack up? Try the new https://t.co/iXj7ZJdxfx VC Pitch Deck Analyzer -> https://t.co/S5UFYzoN7a We’ll share how you stack up against 4,000+ other start-ups. And we’ll provide you honest and confidential feedback on how to do better. https://t.co/YtZxaYnamq
I had a blast having Thomas Laffont on Uncapped. He's the cofounder of Coatue, a $70B AUM firm investing from inception through IPO. We discussed how he makes sense of the current AI cycle, what he thinks will happen to software...
Congrats to @alexchantavy, @kunaalsikka, and @SubImageSec on their $4.2M seed! From the creators of Cartography at @Lyft, SubImage is an open-core alternative to Wiz, using AI to show how vulnerabilities and access paths lead to compromise. https://t.co/HpMp0e8sfN https://t.co/KMyFtUYNkC
Very good cold emailing advice from @HeidiRoizen of @thresholdvc https://t.co/Ak8orSOI2F
Project Europe has product market fit so much faster and so much stronger than even we hoped. In the first 6 months: - 10 cracked teams invested in So what… of those 10: - 1 acquired by category leader - 1...
