
In this episode, a16z’s Raghu Raghuram talks with Google’s Amin Vahdat and Cisco’s Jeetu Patel about the massive physical build‑out required for AI, covering everything from custom chips and power grids to global data‑center networks. They frame this as an "AI industrial revolution" where compute, power and networking become scarce resources, driven by geopolitical competition and the need for hardware‑software‑network co‑design. The guests explain that enterprises are only at the early stage of a CapEx super‑cycle, and that future AI workloads—especially inference, reinforcement learning and multi‑site computing—will reshape how systems are built and operated.
" Companies underestimate 23 and 24 year-olds. The new playbook for these AI startups is actually gonna be much more about hire the AI generalist, this 23, 24, 25-year-old who's really native in AI." @DavidCahn6 Do you agree and how do...
Tanay Tandon (@tanay_tandon) is the co-founder and CEO of Athelas/Commure, the AI operating system for healthcare. Commure powers 20M+ appointments annually and processes $25B+ in claims volume, helping clinicians and health systems work faster, smarter, and spend more time on...

In this episode, founder and mayor‑pro‑tem Nichole Sterling pitches My Town AI, an AI‑driven civic‑intelligence platform that gives small towns access to data, workflow automation and low‑cost digital twins to solve grant‑writing bottlenecks and operational blind spots. She illustrates how...
The single best way to meet a lot of high quality LPs fast. Find out when your competitors AGMs are. Reach out to their LPs knowing they will be in town on those dates. They always want to fill their...
So many on X say founders need to be “great storytellers.” Hogwash. And it leads to founders selling bulls**t. Look, you gotta tell the story. But no matter what, if you are successful, you’ll get good at the story by...

In this episode, Anastasia Soare recounts her journey from a Romanian immigrant running a one‑room Beverly Hills salon to creating a global beauty empire valued at roughly $3 billion, highlighting the power of relentless focus on a niche—eyebrows. She shares key...

Next-gen autonomous maritime defense leader SAILDRONE accepts $50M investment from legacy prime Lockheed partner for weaponized missile launchers 🤖+⛵️+🚀 = 🇺🇸 https://t.co/E9NrWbePNv

Decagon, founded in late 2023, scaled to eight‑figure ARR in roughly 18 months by selling AI customer‑service agents to major enterprises including Hertz and Chime, claiming roughly $800K in annual savings for every $250K spent. Backed by Accel at Series...
Excited to work with @ChEMcShane Evan and the team @ElectroflowTech on building globally competitive LFP production as part of our overall storage gap thesis
Trying to address all the questions on AI valuations, margins to AI vendors and infrastructure, huge investments in data centers, chips, circular economics, robotics, energy and more with @akshay of @theinformation: https://t.co/0qKruLwEvv

In this episode, Jan Szilagyi, co‑founder of Reflexivity, explains how his AI‑driven market research platform transforms raw market data into an analytical partner for top hedge funds, embedding principles from legends like Stanley Druckenmiller. He details the platform’s differentiation, its...
a day to remember: a new @airstreet epoch begins as @nvidia becomes the first 5t company fortuitous timing? i think not!

SaaS + large unsexy market = gold Live on @acquiredotcom: Referral SaaS helping contractors (plumbing, HVAC, roofing etc) share & track jobs. > $32K TTM revenue > $26K TTM profit > 84% margins Turning WOM into recurring income. Full listing: https://t.co/NqMh8TRUsA https://t.co/hiQW7jDrXJ

A curated collection of 40+ free investor databases has been published to simplify startup fundraising and offline outbound outreach, pooling lists vetted by The Venture Curator team. The compilation includes large, searchable rolls such as 2,000 US VCs, 900 climate...
Congrats to the @Whatnot team on raising at $11.5B A few unknown facts about this amazing cofounder duo @GrantLaFontaine and @loganhead13 1/ They launched in 2020 right before COVID hit. 2/ in the early days, they even funded payroll for some of the...
🦜Parrot (https://t.co/Vp7Z5oZ6Zj) is taking down Duolingo. Parrot is the TikTok for language learning - $715K ARR, doubling every two months. They're turning scrolling into learning. https://t.co/KR8mBvZS29 Congrats on the launch, @byAmirHanna, @TheErikDahl, and @JuliAndreeaH!

UNC Chancellor Lee Roberts outlined an ambitious strategy to make artificial intelligence the university’s guiding focus, merging the School of Data Science and Society with the School of Information and Library Science to dismantle academic silos. He acknowledged the loss...

OpenAI clarifies it has about 30GW of infra committed now. And aspires to a run-rate of one new GW/week at $20bn/GW, meaning (say) $1tr/year
If you aren’t sure how to get to $100m ARR, just get to $1m ARR Then just ask your customers They will basically tell you
Mazama Energy announced it has created the world’s hottest enhanced geothermal system at its Newberry, Oregon pilot, achieving a bottomhole temperature of 629°F (331°C) and targeting 750°F (400°C) by 2026. The company says the superhot EGS can yield up to...
From 1st female GP at @Benchmark to now fully devoting herself to AI, @SarahTavel’s career has been defined by deep intellectual rigor and first-principles thinking. In this minisode, @nchirls & I reflect on how Sarah’s approach offers something every GP &...
OpenAI conversion to PBC https://t.co/3tdPRWR4DU

In the episode, Patagonia CEO Ryan Gellert and Chobani founder Hamdi Ulukaya discuss how they align values with profit, navigating activist government pressure and anticipatory compliance while scaling their businesses. They share strategies for integrating environmental stewardship and immigration support...

At TechCrunch Disrupt 2025, Sequoia managing partner Roelof Botha argued that venture capital should not be treated as an asset class, noting that VC returns are essentially uncorrelated and represent a “return‑free risk.” He pointed out that the number of...
Mantle (https://t.co/acxDq4HklH) is the operating system for every company. Tell Mantle about the grunt work you do and it does it for you in the background, exactly how you would, directly in your stack. Let Mantle do the boring stuff for...
Regarding Public Benefit Corporations: shareholders can insist on upholding the public benefit (cf my speech from 12 years ago after it was signed into law in Delaware). So if you care about AI governance and can afford to, you should...

At TechCrunch Disrupt 2025, Astro Teller, CEO of Alphabet’s X, explained that a moonshot must tackle a huge world problem, propose a product that could eliminate it, and rely on a breakthrough technology, noting X’s 2% hit rate and "fail...

some thoughts on @poolsideai's project horizon announcement last week: building a 2gw ai factory "This level of vertical integration - from model and agent development through to power generation and deployment - gives poolside a durable advantage as AI systems become...

today, @airstreet portfolio co PARIMA (fka Gourmey) has become the first european company to be granted regulatory approval to market a cultivated meat product! the first approval within PARIMA’s global regulatory pipeline was granted in singapore for its cultivated chicken. https://t.co/yCJcg3rH9d

Sequoia Capital managing partner Roelof Botha defended partner Shaun Maguire after Maguire’s July 4 X post calling NYC mayoral candidate Zohran Mamdani an “Islamist,” citing the firm’s commitment to free speech and opinion diversity. The remarks sparked a backlash, an open letter...
The biggest myth in tech is that great product automatically builds a great business.
" I do think margins matter in a world of AI. They're a directional indicator of how much product you've built on top of the foundation models." @DavidCahn6 Do you agree and how do you think about margin in the...
Congrats to @Whatnot on raising $225M at an $11.5B valuation—doubling their valuation in less than a year. Whatnot has built the leading US livestream shopping platform, with $6B+ in goods sold (2x 2024's total). Users now spend 80+ min daily on...

Congrats to @NelsonRay18966, @benrk100, @szymczyk06, and @salespatriot_ on their $5M seed! SalesPatriot is building the next-generation procurement platform for defense and aerospace – replacing decades-old systems with an AI-native platform that helps suppliers quote 7x faster. https://t.co/w4SUzjaqRh

Today is the day. https://t.co/pemXFmUb3A May our flag and our freedom forever wave. Thank you @jamesproud, the whole team @substrate, @ChrisOvitz and the whole team at @LongJourneyVC! Another fund defining moment for us. https://t.co/ND8TXNRbL2
Congrats to @aquariusacquah, @michaelssilver, and the @joinkaizen team on their $4M seed! Kaizen allows companies to deploy complex browser automation in minutes instead of weeks. Kaizen powers critical automation in healthcare, finance, and logistics.
I'm building a Product Hunt for investors. Looking for a few SF-based, early-stage investors to beta test. DM me if interested. :) (will delete this tweet shortly)
Congrats to @HenrikTaro, @LudvigSwanstrom, and @VesenceAI on their $9M seed! Vesence brings AI agents to Microsoft Office for law firms. Built for accuracy and quality control, Vesence helps lawyers avoid costly mistakes across Word & Outlook, already seeing 90% weekly...
We don't praise angels enough. I'd like to take a moment to really shine a light on @ChrisOvitz. He was the true second believer in @substrate. He had so much conviction in them and @jamesproud. He deserves every minute today...

The Power Law remains undefeated https://t.co/9EEvSYDfxl
"The lesson that punches you in the stomach in venture is you can't make companies succeed as a venture capitalist. The company succeeds because of the founder and maybe you helped a little bit." Love to hear your thoughts on this...
Founders don’t wait for perfect days. They work tired. They work late. They work when everyone doubts them. No one’s coming to save you. It’s on you to build it.
Today, we're launching @Sequoia's latest seed and venture funds to partner with outlier founders at the start of their journey. There's never been a more exciting time to be a founder. Nearly every industry will be disrupted by AI. So far, the...
"The best companies are going from $0-$100M in revenue very very quickly. As an investor, you have to believe that this company is going to be in the $0-$100M club". @DavidCahn6 Love to hear your thoughts on the required growth...

The latest data from @cartainc is brutal. Of 547 Series B deals in 2018: - Figma did 100x ... but - 39% are worth 1x or less - Only 34% are worth 2x or more after 7 years But - 11.7% do achieve...
Often it turns out that when backing very young founders it isn't as much about being right early, it's more about staying in the room when you're wrong…
"Most of the great investments I have made I was the only term sheet. This idea that the best companies are always super hot rounds is wrong." @DavidCahn6 Have your best investments always been competitive @chadbyers @infoarbitrage @honam @Alfred_Lin? https://t.co/MWp77TBZzR
Rebooting semiconductor supply chains is a moonshot silicon valley needed to take on for US resilience. GC backed Substrate 3+ years ago. Stoked to see this unveiled today. America invented semiconductors. We will lead again.

When 20VC led the Series A for Fyxer they were at $1M ARR. Today, they are adding $1M a week. 🚀 https://t.co/qvjg8Ke7uw