Today's Healthcare Pulse
Lawmakers push to codify wearable device regulations
U.S. legislators are consulting with wearable‑device stakeholders to draft legislation that would codify existing FDA guidance into law, creating a clear regulatory pathway for fitness trackers and smart watches that fall outside the current medical‑device definition.
Also developing:
By the numbers: Kardigan targets $1.4B valuation in US IPO
Nurses Aren’t Burned Out, They’re Being Burned by the System
Recent data shows 53% of nurses consider leaving monthly, indicating systemic burnout. The national turnover rate of 16.4% costs about $61,110 per replacement, harming patient care and morale. HR leaders must address root causes—understaffing, erratic schedules, limited autonomy—through workforce planning, clear role design, and leadership training. Implementing intentional career pathways and continuous feedback can stabilize the nursing workforce.
AngioDynamics Expands European Indications for NanoKnife System
AngioDynamics announced that its NanoKnife system now holds European CE‑mark indications for soft‑tissue ablation of liver, kidney, prostate and pancreas tumours, including intermediate‑risk prostate cancer. The device uses irreversible electroporation (IRE), a non‑thermal technology that destroys cancer cells while sparing...
Serina Therapeutics Enrols First Patient for SER-252 Trial
Serina Therapeutics has enrolled the first patient in its Phase Ib registrational trial of SER‑252 for advanced Parkinson’s disease. The study, conducted with Parkinson’s Australia and Neuroscience Trials Australia, will assess safety, pharmacokinetics, tolerability and early efficacy, with dosing slated to...
Syngene and VivaMed Collaborate on Therapeutic Programmes
Syngene International has entered a strategic collaboration with VivaMed BioPharma to advance AI‑derived drug repurposing programmes. The partnership combines Syngene’s pre‑clinical development capabilities with VivaMed’s AI‑generated therapeutic hypotheses, creating a pathway from computational hits to translational validation. Together they will...
Application Spotlight: AI-Designed Patient-Specific Spinal Implants Set for First In-Human Procedures in 2026
Nivalon, founded by Todd Hodrinsky and Marcel Janse, is preparing to launch its AI‑designed, patient‑specific spinal implant system, EvoFlex, in first‑in‑human trials slated for 2026. The implants are generated through machine‑learning algorithms that model each patient’s vertebral geometry, aiming to...
Accelerating Rare Disease Cures with ASOs, Gene Editing, and AI
Professor Matthew Wood, Oxford’s leading neuroscientist, heads the Oxford‑Harrington Rare Disease Centre, a partnership designed to fast‑track therapies for rare neuromuscular and genetic disorders. He outlines a vision to make antisense oligonucleotides (ASOs) and gene‑editing tools more modular, scalable, and...
4.2m Eye Health Research Hub Set for North East
A £4.2 million Northern Ophthalmic Research and Innovation Institute (NORI) is being established in North East England to turn routine eye scans into early‑warning tools for serious illnesses. The hub, hosted by the University of Sunderland, will link eye images with...
AM Best’s Briefing – Health: Medicare Advantage – Challenges and Opportunities
The episode provides an overview of the current Medicare Advantage (MA) landscape, highlighting regulatory changes, enrollment trends, and financial pressures facing insurers. It examines challenges such as rising cost of care, tighter network requirements, and the impact of the Medicare...
Leica Launches CM1950 Cryostat with DualEcoTec Cooling System
Leica Biosystems, a Danaher subsidiary, unveiled the Leica CM1950 cryostat equipped with DualEcoTec cooling. The device cools specimens up to three times faster and chambers up to twice as fast, slashing setup and case times. It employs a near‑zero global...
Boehringer Ingelheim Secures US FDA’s EUA for NexGard and NexGard COMBO to Treat NWS
Boehringer Ingelheim received an Emergency Use Authorization (EUA) from the U.S. FDA for its NexGard chewable tablets to treat New World screwworm (NWS) infestations in dogs and puppies, and for NexGard COMBO topical solution to treat NWS in cats and...
It’s Time for an End to Two-Tier Tech in the NHS
The NHS is rapidly adopting AI and patient‑facing tools, yet back‑office staff such as roster managers remain stuck with outdated systems. This digital divide fuels stress, mismatched rotas, and higher temporary‑staff costs, contributing to the wider retention crisis. Trusts that...
Smart Insole to Predict and Prevent Elderly Falls
University of Bristol engineer Dr. Jiayang Li has created a smart shoe insole equipped with 253 micro‑sensors that map pressure and gait in real time. The device consumes only 100 microwatts, enabling up to three months of operation on a...
Could Medical Care Help Cure China’s Services Trade Deficit?
China’s medical tourism is gaining traction as foreign patients praise rapid, affordable care in megacities like Shanghai and Beijing. While the absolute number of inbound patients remains modest, industry insiders see a growing pipeline driven by visa‑free entry, expanding international...
Grail's Cancer Test Misses Primary Study Goal in UK Study
Grail announced that its Galleri multi‑cancer blood test failed to achieve the primary endpoint in a large United Kingdom clinical trial. The study, which evaluated the test’s ability to detect early‑stage cancers across dozens of tumor types, showed promising signals...
Rare Disease Month Developments – Part 3: The Ugly (Just Kidding) – See You at Rare Disease Week
Rare Disease Week convenes on Capitol Hill, bringing patients, advocates, regulators, and industry together to shape policy for rare disease therapies. Hyman, Phelps & McNamara will be prominently represented, highlighted by Frank Sasinowski receiving the EveryLife Foundation’s Abbey Lifetime Achievement...
HHS OCR Settles HIPAA Security Rule Investigation with Top of the World Ranch Treatment Center
The U.S. Department of Health and Human Services Office for Civil Rights settled with Top of the World Ranch Treatment Center after a phishing attack exposed ePHI for 1,980 patients. OCR fined the provider $103,000 and imposed a two‑year corrective...
Electronic Mesh Spurs Islet Cell Maturation, Could Aid Diabetes Care
Researchers at the University of Pennsylvania and Harvard have created an ultrathin, flexible electronic mesh that can be implanted into developing pancreatic tissue. The mesh delivers a 24‑hour rhythmic electrical pulse, coaxing stem‑cell‑derived islet cells toward functional maturity and synchronized...
Combining PET and MRI Data May Be Key to Differentiating New Type of Dementia
Researchers have demonstrated that combining 18F‑FDG PET with high‑resolution MRI can reliably separate limbic‑predominant age‑related TDP‑43 encephalopathy (LATE) from Alzheimer’s disease in living patients. By creating stereotactic surface projection PET templates from autopsy‑confirmed cases and integrating MRI volumetry, the team...
Vaccine Protects Against Multiple Respiratory Viruses, Bacteria, and Allergens in Mice
Stanford researchers have created an intranasal vaccine that elicits a combined innate‑adaptive response, providing broad lung protection in mice. The formulation, containing TLR agonists and a harmless antigen, shielded animals for at least three months against SARS‑CoV‑2, other coronaviruses, two...
Rising Healthcare Costs Strain Health System Margins
Healthcare spending surged as higher service volume boosted hospital revenues but also drove operating costs higher, pushing the median health‑system margin down to 1.3% in December from 1.5% in November. Labor expenses rose 4.2% year‑over‑year while supply costs jumped 12.3%,...
Cityblock Health Makes The Home ‘Even More Central,’ Expands Long-Term Services, Supports
Cityblock Health announced the rollout of its long‑term services and supports (LTSS) program across more than ten states, extending the model that began in Massachusetts and is already active in New York, North Carolina and Indiana. The offering blends regular...
Utah Launches State-Approved AI Prescription Refill Pilot as States Expand Health AI Oversight
Utah’s Department of Health has green‑lit a 12‑month pilot that lets an approved artificial‑intelligence system automatically process prescription refills for chronic medications. The AI checks dosage, patient history, and insurance eligibility before sending the order to participating pharmacies, aiming to...
Gel Helps Mini Spinal Cords to Heal From Injury
Researchers have engineered miniature, three‑dimensional spinal‑cord organoids that can be deliberately injured and subsequently repaired with a biocompatible gel. The gel promotes cell survival and rapid axonal regrowth, effectively modeling the healing cascade observed in vivo. This human‑derived platform provides...
Are Obesity Drugs Causing a Severe Complication? What the Science Says
The United Kingdom and Brazil have issued safety warnings linking GLP‑1 weight‑loss drugs to acute pancreatitis after recording 19 and 6 deaths respectively. Reports include roughly 1,300 UK and 145 Brazilian pancreatitis cases among millions of users, though the overall...
Amicus Therapeutics Inc (FOLD) Q4 2025 Earnings Call Transcript
Amgen reported double‑digit revenue and earnings growth for 2025, driven by strong performance across its oncology, rare‑disease, biosimilar and general‑medicine portfolios. Fourteen products surpassed $1 billion in sales, with Repatha, Evenity and Tespire each posting over 30% year‑over‑year growth. The company...
![[Correspondence] Why Ukraine's Energy Insecurity Is a Maternal Health Crisis](https://hixhlmpcokxhartfkpyi.supabase.co/storage/v1/object/public/images/thumbnails/b09028a36dc3b49cdea2e70aeb73b513.webp)
[Correspondence] Why Ukraine's Energy Insecurity Is a Maternal Health Crisis
The Russian invasion has turned Ukraine’s energy grid into a weapon, leaving maternity hospitals without reliable power, heat, and medical equipment. Repeated strikes have caused 23 major attacks on health facilities this year, pushing premature‑birth rates to twice the national...
ViVE
ViVE 2025 convened leading health‑tech innovators to examine how security, artificial intelligence and other emerging technologies are reshaping digital health. Speakers highlighted AI‑driven diagnostics, robust cybersecurity frameworks, and interoperable platforms as essential for scaling patient‑centric care. The event also showcased...
'Digital Blood Testing' Now at Hand
A collaborative team led by UNSW and Nutromics has demonstrated a wearable patch that continuously measures vancomycin levels using DNA‑based aptamer sensors. Published in Nature Biotechnology, the pilot trial showed the patch can track drug concentration in interstitial fluid, offering...
AHA Unveils ‘We Care, We Vote’ Campaign To Engage Candidates Ahead Of Midterms
The American Hospital Association (AHA) has launched the “We Care, We Vote” campaign to mobilize its member hospitals ahead of the 2026 midterm elections. The initiative offers a dedicated website featuring voter‑registration tools, turnout guides, and a questionnaire that helps...
NSA Issues Guidelines on Zero Trust Architecture
The National Security Agency has issued a two‑phase Zero Trust Implementation Guidelines to help organizations adopt zero‑trust architecture in line with Department of Defense standards. The guidance details specific activities and requirements, acknowledging that implementation can be resource‑intensive and costly....
STAT+: Key Study of Grail’s Cancer Detection Test Fails in Setback for Company
Grail’s multi‑cancer blood test Galleri failed to meet its primary endpoint in a large NHS‑partnered study, casting doubt on its early‑detection claims. The test, priced at $1,000, generated $136.8 million from 185,000 units sold in 2025 but remains unapproved by the...
ASPR Announces Investment to Increase Domestic Production of Essential Drugs
The Administration for Strategic Preparedness and Response (ASPR) announced its first Defense Production Act Title III investment to boost U.S. manufacturing of essential drugs. The funding targets the chronic shortage of oseltamivir, the antiviral known as Tamiflu, by supporting domestic production...
Study Finds Nearly 3 Million MA Beneficiaries Forced to Find Alternative Coverage for 2026
A JAMA study released Feb 18 reveals that 10 % of Medicare Advantage (MA) beneficiaries—about 2.9 million people—must secure alternative coverage for 2026 as plans exit the market, up from 6.9 % in 2025. The displaced enrollees are disproportionately in preferred‑provider‑organization, non‑special‑needs, small‑carrier, and...
Physicians Must Evolve Leadership Beyond Clinical Skills
What got you here won’t get you there: a physician’s guide to leadership http://dlvr.it/TR3W2k Physician #HealthIT
Healthcare Confuses PE with VC; Transparency Needed
I've noticed that PE and VC are getting lumped together by healthcare industry folks that I know as if they're the same thing. I'm not sure how we solve this problem but I suspect having more transparent conversations about it...
STAT+: In First Speech to Her FDA Staff, Høeg Says She’ll Scrutinize RSV Shots and SSRIs in Pregnancy
FDA Commissioner Tracy Beth Høeg, in her inaugural staff address, announced a renewed focus on evaluating the safety of antidepressants prescribed during pregnancy and monoclonal antibody RSV prophylaxis for infants. She highlighted gaps in existing safety monitoring and pledged more...
Galleri Test Misses Primary Goal, Shows Secondary Promise
A key study of $GRAL's Galleri test in the UK failed to reach its primary endpoint, but showed benefits on a secondary endpoint. Tell me what you all think. https://t.co/CDrvokqPop
HopeHealth CEO: Hospice in ‘Significant Growth’ Period
HopeHealth, a nonprofit health system serving Rhode Island and southeastern Massachusetts, celebrated its 50th anniversary as the nation’s second hospice and highlighted a period of significant growth in hospice and palliative care. CEO Diana Franchitto noted that aging demographics and...
Pharmaceutical Executive Daily: FDA Plans to Remove Two Study Requirement for New Drug Approvals
The FDA announced it will drop the historic requirement for two adequate and well‑controlled studies in certain new‑drug approval pathways, a move that could accelerate timelines and lower development costs. The change is especially relevant for therapies targeting unmet medical...
Overlooked and Undervalued: Why Novo Nordisk Stock Deserves Attention
Novo Nordisk’s shares have slumped 66% from their 2024 peak, reflecting weak 2026 guidance and fierce competition from Eli Lilly in the GLP‑1 arena. The Danish firm recently introduced the first oral GLP‑1 pill, positioning it ahead of Lilly’s upcoming tablet and...
ACIP February Meeting Cancelled: Report
The Advisory Committee on Immunization Practices (ACIP) cancelled its scheduled February 25‑27, 2026 meeting, and no new date has been announced. The cancellation occurs amid a wave of senior HHS leadership changes, including the departure of Deputy Secretary Jim O’Neill and General...
Lower Glucose by Living High
Researchers at Gladstone Institutes discovered that red blood cells (RBCs) act as a primary glucose sink during hypoxia, explaining why people living at high altitude have lower blood sugar. PET/CT scans showed 70% of the extra glucose clearance in hypoxic...
Examining Vaccine Development Amid America's Science‑Anti‑Science Divide
Many thanks to Freedom Together Foundation medical research consortium for hosting my remarks this week @RockefellerUniv discussing our vaccine development program and my work on the history of medical science vs anti-science in America https://t.co/etbLqiezEA
Chronilogix Integrates with Balance for Life to Expand AI-Driven Behavioral Health and Chronic Care Support
Chronilogix announced an integration that embeds its AI‑powered coaching technology into the Balance for Life wellness app. The combined solution delivers on‑demand behavioral health support for depression, anxiety and stress, while also addressing chronic condition management. By offering 24/7 personalized...
Understanding the 4 Models of Health Care: Where the U.S. Fits
The article outlines the four canonical health‑care system models—Beveridge, Bismarck, national single‑payer, and hybrid—and shows that the United States operates a hybrid structure combining elements of each. It highlights WHO’s six criteria for high‑performing systems and notes that despite world‑class...
Eli Lilly Announces Positive Results for Treating Crohn’s Disease with Omvoh
Eli Lilly reported that its biologic Omvoh (mirikizumab) sustained steroid‑free remission for three years in Crohn’s disease patients in the Phase 3 VIVID‑2 open‑label extension study. More than 90% of participants remained in remission, with 80% experiencing relief from bowel urgency. The...
Dock Health Introduces Its Productivity Platform at Mayo Clinic to Modernize Operational Workflows
Dock Health announced that its productivity platform is now deployed at Mayo Clinic to automate referral and specialty workflows across cardiovascular, e‑consult and contract programs. The solution creates structured, real‑time workflows that trigger when orders enter the EHR, automatically assigning...
IL-6 as a Measure of Peripheral Inflammation Is More Often Elevated in Cognitively Impaired Individuals
A recent open‑access study of 514 Canadian seniors examined peripheral inflammation using IL‑6 and C‑reactive protein. The analysis revealed that elevated IL‑6 levels were present in 12% of cognitively normal participants but rose sharply to 36‑55% among Alzheimer’s, mixed dementia,...
Lonza Boosts Advanced Synthesis Capabilities for Bioconjugates
Lonza has expanded its advanced synthesis portfolio to provide end‑to‑end support for antibody‑drug conjugates (ADCs) and other bioconjugates. The company fully integrated the Synaffix‑derived ADC platform—including GlycoConnect® conjugation, HydraSpace® spacers and toxSYN® linker payloads—into its services. A new dual‑payload ADC...
EBV DNA Linked to Multiple Autoimmune Diseases in 800k Genomes
🆕@Nature Genome sequencing of >800,000 people finds Epstein-Barr virus reads and their association with other autoimmune diseases besides multiple sclerosis, including type 1 diabetes, inflammatory bowel disease, and hypothyroidism https://t.co/FKCV4OInT5